

Compact for Safe Cosmetics
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Animal Testing Policy |


| Ingredients used by this brand: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. This chart indicates that research studies have found that exposure to one or more ingredients in products by this brand -- not the products themselves -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
See all 45 products by Ion Color Brilliance
Product type(s) by this brand in Skin Deep: hair color and bleaching (45)
| score | data gap | products * | concerns | |
| RESORCINOL | 8 | 55% | 26 products | Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| P-PHENYLENEDIAMINE | 10 | 52% | 39 products | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| CETEARETH-50 | 5 | 71% | 44 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| ETHANOLAMINE | 7 | 63% | 1 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| P-AMINOPHENOL | 8 | 57% | 34 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| FRAGRANCE | 8 | 100% | 45 products | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| PROPYLENE GLYCOL | 4 | 58% | 45 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| SODIUM LAURETH-5 SULFATE | 4 | 86% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE | 4 | 76% | 40 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| DIMETHICONE PEG-8 MEADOWFOAMATE | 4 | 76% | 40 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-15 COCOPOLYAMINE | 4 | 76% | 5 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-40 HYDROGENATED CASTOR OIL | 4 | 75% | 40 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| HC RED 3 | 6 | 67% | 4 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| M-AMINOPHENOL | 6 | 65% | 7 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| P-METHYLAMINOPHENOL SULFATE | 5 | 59% | 1 products | Cancer, Allergies/immunotoxicity, Occupational hazards |
| 5-AMINO-6-CHLORO-O-CRESOL | 5 | 73% | 6 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity |
| ALCOHOL DENATURED | 4 | 72% | 1 products | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| 2-AMINO-6-CHLORO-4-NITROPHENOL | 5 | 71% | 1 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity |
| 4-AMINO-2-HYDROXYTOLUENE | 5 | 68% | 8 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity |
| TOLUENE-2,5-DIAMINE SULFATE | 5 | 68% | 5 products | Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| COCAMIDOPROPYL BETAINE | 5 | 63% | 40 products | Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| LAURETH-3 | 4 | 95% | 1 products | Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| TETRASODIUM EDTA | 1 | 80% | 1 products | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| AMMONIA | 3 | 79% | 45 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| ETHOXYDIGLYCOL | 1 | 77% | 40 products | Organ system toxicity (non-reproductive) |
| T-BUTYL HYDROQUINONE | 4 | 69% | 1 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| SODIUM SULFITE | 3 | 84% | 45 products | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| EDTA | 2 | 78% | 44 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| 2-METHYL-5-HYDROXYETHYLAMINOPHENOL | 3 | 73% | 9 products | Cancer, Allergies/immunotoxicity |
| AMMONIUM LAURYL SULFATE | 1 | 73% | 4 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARIC ACID | 2 | 72% | 4 products | Neurotoxicity, Irritation (skin, eyes, or lungs) |
| BASIC RED 2 | 2 | 72% | 5 products | Cancer, Neurotoxicity |
| N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE | 3 | 69% | 1 products | Cancer, Allergies/immunotoxicity |
| 2-METHYLRESORCINOL | 2 | 84% | 31 products | Allergies/immunotoxicity |
| OLEIC ACID | 1 | 82% | 1 products | Irritation (skin, eyes, or lungs) |
| GLYCERIN | 2 | 74% | 45 products | Organ system toxicity (non-reproductive), Occupational hazards |
| CETEARYL ALCOHOL | 0 | 93% | 40 products | none identified |
| CETYL ALCOHOL | 1 | 87% | 44 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ERYTHORBIC ACID | 1 | 87% | 41 products | none identified |
| OLEYL ALCOHOL | 1 | 87% | 4 products | Irritation (skin, eyes, or lungs) |
| 1-DODECANOL | 1 | 84% | 41 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| MYRISTYL ALCOHOL | 1 | 84% | 41 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARYL ALCOHOL | 1 | 84% | 40 products | Irritation (skin, eyes, or lungs) |
| 2,4-DIAMINOPHENOXYETHANOL HCL | 1 | 76% | 23 products | Cancer |
| PALMITIC ACID | 1 | 76% | 4 products | Neurotoxicity |
| POLYQUATERNIUM-22 | 0 | 100% | 44 products | none identified |
| SIMETHICONE | 0 | 100% | 44 products | none identified |
| WHEAT GERM PROTEIN | 0 | 100% | 45 products | none identified |
| WATER | 0 | 0% | 45 products | innocuous |
* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human nervous system toxicant - moderate evidence | P-PHENYLENEDIAMINE | |
| Limited evidence of reproductive toxicity | ALCOHOL DENATURED | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN, P-AMINOPHENOL, PROPYLENE GLYCOL | |
| One or more animal studies show reproductive effects at high doses | EDTA, ETHANOLAMINE, ETHOXYDIGLYCOL, M-AMINOPHENOL, T-BUTYL HYDROQUINONE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin | products for use on damaged skin | BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, DIMETHICONE PEG-8 MEADOWFOAMATE, PEG-15 COCOPOLYAMINE, PEG-40 HYDROGENATED CASTOR OIL, CETEARETH-50 |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off | products that are intended to be left on the skin | ETHANOLAMINE |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | RESORCINOL, P-PHENYLENEDIAMINE, T-BUTYL HYDROQUINONE | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | 2-AMINO-6-CHLORO-4-NITROPHENOL, 4-AMINO-2-HYDROXYTOLUENE, HC RED 3, M-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, TOLUENE-2,5-DIAMINE SULFATE, 5-AMINO-6-CHLORO-O-CRESOL | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - any | 2,4-DIAMINOPHENOXYETHANOL HCL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, M-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, P-PHENYLENEDIAMINE, RESORCINOL, TOLUENE-2,5-DIAMINE SULFATE, 5-AMINO-6-CHLORO-O-CRESOL, BASIC RED 2, 2-AMINO-6-CHLORO-4-NITROPHENOL, AMMONIUM LAURYL SULFATE, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, COCAMIDOPROPYL BETAINE, DIMETHICONE PEG-8 MEADOWFOAMATE, ETHANOLAMINE, HC RED 3, PEG-15 COCOPOLYAMINE, PEG-40 HYDROGENATED CASTOR OIL, PROPYLENE GLYCOL, T-BUTYL HYDROQUINONE, CETEARETH-50 |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Strong evidence of human neurotoxicity | P-PHENYLENEDIAMINE | |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at very low doses | STEARIC ACID, BASIC RED 2 | |
| One or more animal studies show brain and nervous system effects at low doses | PALMITIC ACID, SODIUM SULFITE | |
| One or more animal studies show brain and nervous system effects at moderate doses | EDTA, ETHANOLAMINE, M-AMINOPHENOL, OLEIC ACID, P-AMINOPHENOL, RESORCINOL, CETEARETH-50 | |
| One or more animal studies show brain and nervous system effects at high doses | 4-AMINO-2-HYDROXYTOLUENE, ETHOXYDIGLYCOL, GLYCERIN, PROPYLENE GLYCOL |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of endocrine disruption | RESORCINOL | |
| One or more animal studies show endocrine system disruption at high doses | 4-AMINO-2-HYDROXYTOLUENE, ALCOHOL DENATURED, ETHANOLAMINE, ETHOXYDIGLYCOL, GLYCERIN, HC RED 3, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, P-PHENYLENEDIAMINE, PROPYLENE GLYCOL, STEARIC ACID |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | COCAMIDOPROPYL BETAINE, FRAGRANCE, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, P-PHENYLENEDIAMINE, RESORCINOL | |
| Human immune and respiratory toxicant - strong evidence | ETHANOLAMINE | |
| Human skin toxicant - strong evidence | 2-AMINO-6-CHLORO-4-NITROPHENOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, HC RED 3, M-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, TOLUENE-2,5-DIAMINE SULFATE, 5-AMINO-6-CHLORO-O-CRESOL | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human immune system toxicant - moderate evidence | SODIUM SULFITE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human respiratory toxicant | P-PHENYLENEDIAMINE | |
| Known human respiratory toxicant | products that may be aerosolized (airborne) | AMMONIA |
| Limited evidence of eye toxicity | products for use around the eyes | TETRASODIUM EDTA |
| Limited evidence of respiratory toxicity | products that may be aerosolized (airborne) | PROPYLENE GLYCOL |
| Possible human immune system toxicant | ETHANOLAMINE, P-AMINOPHENOL, SODIUM SULFITE | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, T-BUTYL HYDROQUINONE, | |
| One or more animal studies show respiratory effects at very low doses | products that may be aerosolized (airborne) | OLEIC ACID, STEARIC ACID, BASIC RED 2 |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | ALCOHOL DENATURED, RESORCINOL, SODIUM LAURETH-5 SULFATE |
| One or more animal studies show broad systemic effects at low doses | EDTA, TOLUENE-2,5-DIAMINE SULFATE, | |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | AMMONIUM LAURYL SULFATE, ETHOXYDIGLYCOL, M-AMINOPHENOL, CETEARETH-50 |
| Classified as toxic or harmful | products for use around the mouth; products for use on the lips | P-METHYLAMINOPHENOL SULFATE |
| Limited evidence of sense organ toxicity | BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, DIMETHICONE PEG-8 MEADOWFOAMATE, PEG-15 COCOPOLYAMINE, PEG-40 HYDROGENATED CASTOR OIL | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | 1-DODECANOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, | |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | CETYL ALCOHOL, MYRISTYL ALCOHOL, OLEYL ALCOHOL, STEARYL ALCOHOL |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | ERYTHORBIC ACID, 2-AMINO-6-CHLORO-4-NITROPHENOL, HC RED 3 | |
| Classified as not expected to be potentially toxic or harmful | CETEARYL ALCOHOL, COCAMIDOPROPYL BETAINE, PALMITIC ACID, WATER |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE | |
| Occupational hazards related to handling | ALCOHOL DENATURED, AMMONIA, ETHANOLAMINE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Used in food or as an additive with limited or no toxicity information available | ALCOHOL DENATURED | |
| Designated as safe for general or specific, limited use in food | 1-DODECANOL, ALCOHOL DENATURED, AMMONIA, BISAMINO PEG/ PPG-41/ 3 AMINOETHYL PG-PROPYL DIMETHICONE, CETYL ALCOHOL, DIMETHICONE PEG-8 MEADOWFOAMATE, ERYTHORBIC ACID, ETHANOLAMINE, ETHOXYDIGLYCOL, GLYCERIN, MYRISTYL ALCOHOL, OLEIC ACID, PALMITIC ACID, PEG-15 COCOPOLYAMINE, PEG-40 HYDROGENATED CASTOR OIL, PROPYLENE GLYCOL, RESORCINOL, SODIUM SULFITE, STEARIC ACID, STEARYL ALCOHOL, T-BUTYL HYDROQUINONE, TETRASODIUM EDTA |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as irritant | EDTA, P-PHENYLENEDIAMINE, RESORCINOL, PROPYLENE GLYCOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | OLEYL ALCOHOL, STEARYL ALCOHOL, SODIUM LAURETH-5 SULFATE |
| Human respiratory irritant - strong evidence | products that may be aerosolized (airborne) | AMMONIA |
| Human skin irritant - moderate evidence | ETHANOLAMINE | |
| One or more animal studies show skin irritation at very low doses | 1-DODECANOL, AMMONIUM LAURYL SULFATE, CETYL ALCOHOL | |
| One or more animal studies show skin irritation at low doses | ALCOHOL DENATURED, MYRISTYL ALCOHOL, OLEIC ACID, STEARIC ACID, TETRASODIUM EDTA, CETEARETH-50 | |
| One or more animal studies show skin irritation at moderate doses | ETHOXYDIGLYCOL, GLYCERIN, M-AMINOPHENOL, P-AMINOPHENOL, PALMITIC ACID | |
| One or more animal studies show skin irritation at high doses | 4-AMINO-2-HYDROXYTOLUENE, P-METHYLAMINOPHENOL SULFATE, SODIUM SULFITE, T-BUTYL HYDROQUINONE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to very low doses | P-PHENYLENEDIAMINE | |
| Allowed workplace exposures restricted to low doses | AMMONIA, ETHANOLAMINE, M-AMINOPHENOL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, RESORCINOL, TETRASODIUM EDTA, TOLUENE-2,5-DIAMINE SULFATE | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN | |
| Allowed workplace exposures restricted to high doses | ALCOHOL DENATURED |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | T-BUTYL HYDROQUINONE | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | P-AMINOPHENOL | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ALCOHOL DENATURED, GLYCERIN, PROPYLENE GLYCOL |
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