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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| Ingredients used by this brand: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
See all 24 products by Bull Frog
Product type(s) by this brand in Skin Deep: insect/pest repellant (1), sunscreen: SPF 15-30 (1), sunscreen: SPF greater than 30 (16)
| score | data gap | products * | concerns | |
| OXYBENZONE (BENZOPHENONE-3) | 9 | 55% | 17 products | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| FRAGRANCE | 8 | 100% | 17 products | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) | 8 | 65% | 14 products | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| SILICA | 1 | 69% | 3 products | Biochemical or cellular level changes |
| IODOPROPYNYL BUTYLCARBAMATE | 4 | 65% | 1 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| DIAZOLIDINYL UREA | 6 | 59% | 1 products | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| SD ALCOHOL 40 | 5 | 77% | 11 products | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN) |
| TITANIUM DIOXIDE (NON-NANO) | 1 | 81% | 1 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| TOCOPHERYL ACETATE | 4 | 81% | 16 products | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| HOMOSALATE | 4 | 74% | 3 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Enhanced skin absorption, Contamination concerns (SALICYLIC ACID, TRIMETHYLCYCLOHEXANOL) |
| OCTISALATE | 3 | 68% | 14 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PROPYLENE GLYCOL | 4 | 60% | 1 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| DISODIUM EDTA | 3 | 78% | 1 products | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| OCTOCRYLENE | 3 | 71% | 17 products | Violations, restrictions & warnings, Biochemical or cellular level changes |
| CYCLOMETHICONE | 2 | 83% | 3 products | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | 2 | 73% | 3 products | Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE) |
| C12-15 ALKYL BENZOATE | 0 | 94% | 11 products | none identified |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | 3 products | none identified |
| ISOSTEARYL ALCOHOL | 0 | 93% | 5 products | none identified |
| MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA) | 1 | 93% | 2 products | Organ system toxicity (non-reproductive) |
| ETHYLHEXYL PALMITATE | 1 | 92% | 3 products | Irritation (skin, eyes, or lungs) |
| MENTHYL ANTHRANILATE | 1 | 92% | 1 products | Organ system toxicity (non-reproductive) |
| SORBITAN STEARATE | 1 | 92% | 1 products | none identified |
| OZOKERITE | 1 | 91% | 2 products | none identified |
| PHENYLETHYL BENZOATE | 1 | 89% | 3 products | none identified |
| HYDROXYPROPYLCELLULOSE | 1 | 88% | 4 products | none identified |
| ISOPROPYL PALMITATE | 1 | 87% | 12 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ISOPROPYL MYRISTATE | 1 | 86% | 12 products | Irritation (skin, eyes, or lungs) |
| PROPIONIC ACID ETHYL ESTER | 1 | 81% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT | 1 | 75% | 13 products | none identified |
| ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT | 1 | 73% | 2 products | none identified |
| ALOE BARBADENSIS (ALOE VERA) OIL | 1 | 73% | 1 products | none identified |
| ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER | 0 | 100% | 12 products | none identified |
| DICAPRYLYL CARBONATE | 0 | 100% | 2 products | none identified |
| NEOPENTYL GLYCOL DIOCTANOATE/ DIISOSTEARATE | 0 | 100% | 1 products | none identified |
| SUCROSE COCOATE | 0 | 100% | 1 products | none identified |
| POLYESTER | 0 | 100% | 3 products | none identified |
| HELIANTHUS ANNUUS (SUNFLOWER) OIL | 0 | 94% | 1 products | none identified |
| XANTHAN GUM | 0 | 94% | 1 products | none identified |
| BEESWAX | 0 | 93% | 2 products | none identified |
| WATER | 0 | 0% | 1 products | innocuous |
* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of carcinogenicity | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| Cancer - not classifiable/not likely to be human carcinogen | products that may be aerosolized (airborne) | SILICA |
| Cancer - limited evidence | SD ALCOHOL 40 | |
| One or more in vitro tests on mammalian cells show positive mutation results | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), MENTHYL ANTHRANILATE | |
| One or more in vitro tests on mammalian cells show positive mutation results | DIAZOLIDINYL UREA, DISODIUM EDTA, PROPYLENE GLYCOL, TOCOPHERYL ACETATE | |
| One or more in vitro tests non-mammalian cells show positive mutation results | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of reproductive toxicity | SD ALCOHOL 40 | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT, ALOE BARBADENSIS (ALOE VERA) OIL | |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL, | |
| One or more animal studies show reproductive effects at moderate doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at high doses | DISODIUM EDTA |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR) | products that may be aerosolized (airborne) | IODOPROPYNYL BUTYLCARBAMATE |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), HOMOSALATE, OCTOCRYLENE, IODOPROPYNYL BUTYLCARBAMATE, OCTISALATE, OXYBENZONE (BENZOPHENONE-3) | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | products for use around the eyes; products for use on the lips | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | ALOE BARBADENSIS (ALOE VERA) FLOWER EXTRACT, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, ALOE BARBADENSIS (ALOE VERA) OIL, DIAZOLIDINYL UREA, IODOPROPYNYL BUTYLCARBAMATE, PROPYLENE GLYCOL |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Moderate evidence of human neurotoxicity | FRAGRANCE | |
| One or more animal studies show brain and nervous system effects at low doses | DISODIUM EDTA | |
| One or more animal studies show brain and nervous system effects at high doses | DIAZOLIDINYL UREA, OXYBENZONE (BENZOPHENONE-3), PROPYLENE GLYCOL | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | SD ALCOHOL 40 |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| One or more studies show weak endocrine disruption | HOMOSALATE | |
| One or more animal studies show endocrine system disruption at high doses | DIAZOLIDINYL UREA, DISODIUM EDTA |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | DIAZOLIDINYL UREA, FRAGRANCE | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) | |
| Human any toxicant - strong evidence | IODOPROPYNYL BUTYLCARBAMATE | |
| Human immune system toxicant - strong evidence | products that may be aerosolized (airborne) | SILICA |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| One or more animal studies show immune effects at low doses | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more human case studies show possible immune effects | OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Associated with immunotoxicity | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human respiratory toxicant | products that may be aerosolized (airborne) | SILICA |
| Limited evidence of respiratory toxicity | products that may be aerosolized (airborne) | PROPYLENE GLYCOL |
| One or more animal studies show respiratory effects at very low doses | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more animal studies show broad systemic effects at low doses | DISODIUM EDTA, ISOPROPYL PALMITATE, | |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | PROPIONIC ACID ETHYL ESTER |
| Limited evidence of gastrointestinal or liver toxicity | IODOPROPYNYL BUTYLCARBAMATE, SD ALCOHOL 40 | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | HYDROXYPROPYLCELLULOSE, OCTISALATE, TOCOPHERYL ACETATE, | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | CYCLOMETHICONE, OZOKERITE |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | DIAZOLIDINYL UREA, ISOPROPYL MYRISTATE, PHENYLETHYL BENZOATE, OCTOCRYLENE, | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Classified as expected to be toxic or harmful | HOMOSALATE, MENTHYL ANTHRANILATE | |
| Classified as expected to be toxic or harmful | MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA) | |
| Classified as not expected to be potentially toxic or harmful | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), BEESWAX, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, ETHYLHEXYL PALMITATE, HELIANTHUS ANNUUS (SUNFLOWER) OIL, ISOSTEARYL ALCOHOL, SORBITAN STEARATE, WATER, XANTHAN GUM |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FRAGRANCE | |
| Occupational hazards related to handling | SD ALCOHOL 40, PROPIONIC ACID ETHYL ESTER |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Used in food or as an additive with limited or no toxicity information available | SD ALCOHOL 40 | |
| Designated as safe for general or specific, limited use in food | products that may be aerosolized (airborne) | SILICA |
| Designated as safe for general or specific, limited use in food | BEESWAX, DISODIUM EDTA, HYDROXYPROPYLCELLULOSE, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, PHENYLETHYL BENZOATE, PROPYLENE GLYCOL, SORBITAN STEARATE, TITANIUM DIOXIDE (NON-NANO), TOCOPHERYL ACETATE, XANTHAN GUM, PROPIONIC ACID ETHYL ESTER |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Classified as skin irritant | PROPYLENE GLYCOL | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | ETHYLHEXYL PALMITATE, ISOPROPYL MYRISTATE |
| One or more animal studies show significant but moderate pulmonary irritation at low doses | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more animal studies show skin irritation at low doses | ISOPROPYL PALMITATE, OCTISALATE, PROPIONIC ACID ETHYL ESTER | |
| One or more animal studies show skin irritation at moderate doses | CYCLOMETHICONE, OZOKERITE, SORBITAN STEARATE | |
| One or more animal studies show skin irritation at high doses | IODOPROPYNYL BUTYLCARBAMATE | |
| Not likely to be a skin irritant in humans | OXYBENZONE (BENZOPHENONE-3) |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | TITANIUM DIOXIDE (NON-NANO) |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | SILICA, | |
| One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CYCLOMETHICONE, PROPYLENE GLYCOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE), OCTOCRYLENE | |
| Does not produces excess reactive oxygen species or other harmful biochemical changes. | OCTISALATE |
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