Calvin Klein || Skin Deep: Cosmetic Safety Reviews

BRAND: Calvin Klein

Manufacturer: Coty, Inc.

BRAND SUMMARY

product score range	3	to	10
product count	101 (browse)
ingredient count	163
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 101 products by Calvin Klein

Product type(s) by this brand in Skin Deep: after shave (2), antiperspirant/deodorant (men's) (2), body spray (1), concealer (1), facial moisturizer/treatment (1), facial powder (1), fragrance for men (6), fragrance for women (2), lip gloss (1), lip plumper (1), mascara (1), moisturizer (2)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	5 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
OXYBENZONE (BENZOPHENONE-3)	9	55%	3 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	14 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	6	65%	3 products	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
SILICA	7	69%	1 products	Cancer, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
EUGENOL	7	56%	5 products	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
COUMARIN	7	46%	7 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BUTYLPARABEN	6	79%	2 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
LAURYL PEG/ PPG-18/ 18 METHICONE	6	76%	1 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8	4	76%	2 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
EXT D&C VIOLET 2	5	73%	4 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
LECITHIN	3	70%	1 products	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
BENZYL ALCOHOL	6	64%	2 products	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
LILIAL	6	64%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BENZYL SALICYLATE	6	62%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity
HYDROXYCITRONELLAL	6	62%	3 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LYRAL	6	62%	3 products	Violations, restrictions & warnings, Allergies/immunotoxicity
BHT	6	61%	1 products	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
GERANIOL	6	61%	7 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CINNAMYL ALCOHOL	6	60%	3 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ISOEUGENOL	6	59%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
TRIETHANOLAMINE	6	58%	3 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
CITRAL	6	57%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	9 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ETHYLPARABEN	5	80%	2 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
D&C RED 30 LAKE	4	72%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
ALCOHOL DENATURED	5	71%	4 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	5 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	2 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
BENZOPHENONE-2	5	67%	3 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
HEXYLENE GLYCOL	5	67%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BENZYL BENZOATE	5	65%	3 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
CITRONELLOL	5	65%	7 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	9 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
EVERNIA FURFURACEA (OAKMOSS LICHEN) EXTRACT	5	63%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
D&C RED 27 LAKE	3	91%	1 products	Developmental/reproductive toxicity, Neurotoxicity
D&C YELLOW 5 ALUMINUM LAKE	4	91%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C BLUE 1 ALUMINUM LAKE	4	91%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5 ALUMINUM LAKE	4	91%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
D&C YELLOW 6 ALUMINUM LAKE	3	89%	1 products	Developmental/reproductive toxicity, Neurotoxicity
SODIUM LAURETH-12 SULFATE	4	88%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-20	3	87%	2 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
POLOXAMER 407	2	82%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO)	4	81%	5 products	Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	2 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
SD ALCOHOL 1	4	77%	5 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
D&C RED 7 LAKE	4	73%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA-COPPER	1	73%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
FD&C RED 4	1	73%	4 products	none identified
D&C RED 28 ALUMINUM LAKE	4	72%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 6	1	70%	1 products	none identified
ALPHA-ISOMETHYL IONONE	4	68%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity
OCTISALATE	3	68%	3 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PHENOXYETHANOL	4	67%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
UREA	4	67%	1 products	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
BENZYL CINNAMATE	4	65%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYL CINNAMAL	4	65%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL	4	60%	4 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LAURETH-4	3	96%	1 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CHROMIUM OXIDE GREENS	3	86%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards
MENTHOL	3	85%	1 products	Organ system toxicity (non-reproductive), Multiple, additive exposure sources
ISOBUTYLPARABEN	3	83%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5	2	82%	6 products	Neurotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE	2	79%	3 products	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
FERRIC FERROCYANIDE	3	76%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
ZINC STEARATE	3	76%	1 products	Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
CI 77491	3	76%	5 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
ACRYLATES COPOLYMER	3	75%	1 products	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
D&C RED 6	0	75%	1 products	none identified
D&C RED 7	0	75%	1 products	none identified
MICA	3	75%	5 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
DIMETHICONE	2	74%	4 products	Violations, restrictions & warnings
D&C YELLOW 10	1	73%	1 products	none identified
ULTRAMARINES	2	90%	1 products	Multiple, additive exposure sources
TOCOPHEROL	2	87%	2 products	Contamination concerns (HYDROQUINONE)
ASPARTIC ACID	2	85%	1 products	Neurotoxicity
GLUTAMIC ACID	2	85%	1 products	Organ system toxicity (non-reproductive), Biochemical or cellular level changes
IRON OXIDES	2	85%	5 products	Persistence and bioaccumulation, Enhanced skin absorption
CHROMIUM HYDROXIDE GREEN	1	84%	1 products	Persistence and bioaccumulation
CYCLOMETHICONE	2	83%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
FD&C BLUE 1	1	83%	4 products	none identified
CYCLOHEXASILOXANE	1	82%	1 products	Persistence and bioaccumulation
TETRASODIUM EDTA	2	81%	4 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PARAFFIN	2	80%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM DEHYDROACETATE	2	78%	2 products	Organ system toxicity (non-reproductive), Occupational hazards
GLYCERIN	2	74%	3 products	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	3 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)	2	73%	3 products	Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE)
AMINOMETHYL PROPANOL	2	71%	1 products	Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE)
SODIUM PCA	2	71%	2 products	Contamination concerns (NITROSAMINES)
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	1 products	none identified
CARMINE	0	94%	3 products	none identified
DIETHYLHEXYL SEBACATE	1	94%	1 products	none identified
CETEARYL ALCOHOL	0	93%	2 products	none identified
PHENYL TRIMETHICONE	0	93%	1 products	none identified
SQUALANE	1	93%	2 products	Irritation (skin, eyes, or lungs)
POLYBUTENE	1	92%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ASCORBIC ACID (VITAMIN C)	1	91%	1 products	none identified
BISMUTH OXYCHLORIDE	1	89%	1 products	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	3 products	none identified
GLYCERYL MONOSTEARATE	1	88%	2 products	none identified
SORBITOL	1	88%	1 products	none identified
CETYL ALCOHOL	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SYNTHETIC BEESWAX	1	87%	1 products	Irritation (skin, eyes, or lungs)
TRISODIUM EDTA	1	86%	1 products	Enhanced skin absorption
PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE	1	86%	1 products	Persistence and bioaccumulation
FRUCTOSE	1	85%	1 products	none identified
POTASSIUM SORBATE	1	85%	3 products	none identified
SODIUM STEARATE	1	83%	2 products	Occupational hazards
GLUCOSE	1	82%	1 products	none identified
POLYSORBATE-60	1	81%	1 products	none identified
PVP	1	81%	1 products	Organ system toxicity (non-reproductive)
SODIUM CHONDROITIN SULFATE	1	80%	1 products	none identified
BUTYLENE GLYCOL	1	79%	3 products	Irritation (skin, eyes, or lungs)
D&C RED 6 LAKE	1	76%	1 products	none identified
TRIDECYL SALICYLATE	1	76%	1 products	none identified
CAPSICUM FRUTESCENS	1	76%	1 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	2 products	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	2 products	none identified
ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER	0	100%	2 products	none identified
DIMETHICONE CROSSPOLYMER	0	100%	2 products	none identified
DIMETHICONE/ VINYL DIMETHICONE CROSSPOLYMER	0	100%	1 products	none identified
FD&C GREEN 5	0	100%	1 products	none identified
HYDROGENATED POLYISOBUTENE	0	100%	1 products	none identified
HYDROLYZED JOJOBA ESTERS	0	100%	2 products	none identified
HYDROXYCELLULOSE	0	100%	1 products	none identified
ISODODECANE	0	100%	1 products	none identified
ISONONYL ISONONANOATE	0	100%	4 products	none identified
PALMITOYL HYDROXYPROPYLTRIMONIUM AMYLOPECTIN/ GLYCERIN CROSSPOLYMER	0	100%	1 products	none identified
PENTAERYTHRITYL TETRAISOSTEARATE	0	100%	1 products	none identified
PHOSPHOLIPIDS	0	100%	2 products	none identified
POLYVINYLALCOHOL CROSSPOLYMER	0	100%	1 products	none identified
SILICA DIMETHYL SILYLATE	0	100%	1 products	none identified
SILICA SILYLATE	0	100%	1 products	none identified
TREE MOSS OIL	0	100%	1 products	none identified
ATELOCOLLAGEN	0	100%	1 products	none identified
CAPRYLYL DIMETHICONE ETHOXY GLUCOSIDE	0	100%	1 products	none identified
CI 77492	0	100%	1 products	none identified
POLYDODECANAMIDEAMINIUM TRIAZADIPHENYLETHENESULFONATE	0	100%	1 products	none identified
ACETYL HEXAPEPTIDE-8	0	100%	1 products	none identified
CETEARYL METHICONE	0	99%	1 products	none identified
CETYL DIMETHICONE	0	99%	1 products	none identified
SORBITAN ISOSTEARATE	0	99%	1 products	none identified
ALANINE	0	94%	1 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER)	0	94%	3 products	none identified
C18-36 ACID TRIGLYCERIDE	0	94%	1 products	none identified
CAPRYLYL GLYCOL	0	94%	1 products	none identified
DEXTRIN	0	94%	1 products	none identified
DICALCIUM PHOSPHATE	0	94%	1 products	none identified
NYLON-12	0	94%	1 products	none identified
THEOBROMA CACAO (CACAO) SEED BUTTER	0	94%	1 products	none identified
XANTHAN GUM	0	94%	1 products	none identified
CARBOMER	0	93%	1 products	none identified
COPERNICIA CERIFERA (CARNAUBA) WAX	0	93%	1 products	none identified
GLYCERYL STEARATE SE	0	93%	2 products	none identified
PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL	0	93%	1 products	none identified
SODIUM CHLORIDE	0	0%	1 products	innocuous
SUCROSE	0	0%	1 products	innocuous
WATER	0	0%	16 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Cancer - not classifiable/not likely to be human carcinogen	products that may be aerosolized (airborne)	SILICA
Cancer - not classifiable/not likely to be human carcinogen		BHT, CHROMIUM OXIDE GREENS, COUMARIN, LIMONENE, FD&C BLUE 1, FD&C RED 4, FD&C YELLOW 6, PVP, TRIETHANOLAMINE, CI 77491, CHROMIUM HYDROXIDE GREEN
Not likely to be carcinogenic in humans		EUGENOL, STEARIC ACID
Cancer - limited evidence		ALCOHOL DENATURED, EXT D&C VIOLET 2, RETINYL PALMITATE, SD ALCOHOL 1
One or more in vitro tests on mammalian cells show positive mutation results		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)
One or more in vitro tests on mammalian cells show positive mutation results		ASCORBIC ACID (VITAMIN C), ASPARTIC ACID, BENZOPHENONE-2, BENZYL ALCOHOL, BUTYLPARABEN, D&C RED 28 ALUMINUM LAKE, DISODIUM EDTA, ETHYLPARABEN, FD&C YELLOW 5, GERANIOL, GLUCOSE, GLUTAMIC ACID, GLYCERIN, ISOEUGENOL, MENTHOL, METHYLPARABEN, POTASSIUM SORBATE, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM CHLORIDE, SODIUM DEHYDROACETATE, SODIUM HYDROXIDE, SORBITOL, SUCROSE, TOCOPHEROL, TOCOPHERYL ACETATE, UREA
One or more animal studies show tumor formation at moderate doses		PARAFFIN, PEG-100 STEARATE,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests non-mammalian cells show positive mutation results		CINNAMYL ALCOHOL, LINALOOL, OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL
One or more animal studies show tumor formation at high doses		POLYSORBATE-60, CITRAL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		SD ALCOHOL 1
Human nervous system toxicant - moderate evidence		D&C RED 27 LAKE, D&C RED 28 ALUMINUM LAKE, D&C RED 30 LAKE, D&C RED 7 LAKE, D&C YELLOW 5 ALUMINUM LAKE, D&C YELLOW 6 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, FD&C YELLOW 5 ALUMINUM LAKE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3), ALCOHOL DENATURED
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, PROPYLENE GLYCOL,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at high doses		BENZYL ALCOHOL, BHT, BUTYLENE GLYCOL, LILIAL, CINNAMYL ALCOHOL, CITRAL, COUMARIN, DISODIUM EDTA, ETHYLPARABEN, FD&C YELLOW 5, ISOEUGENOL, POLYSORBATE-60, SODIUM DEHYDROACETATE, UREA, PEG-100 STEARATE, SODIUM CHONDROITIN SULFATE, FD&C YELLOW 6

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	products for use around the mouth, lips, eyes, or on damaged skin	EXT D&C VIOLET 2, FD&C RED 4
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C RED 6, D&C RED 7, D&C YELLOW 10, DISODIUM EDTA-COPPER, FD&C YELLOW 6
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-20, LAURYL PEG/ PPG-18/ 18 METHICONE, PEG-8, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), PHENOXYETHANOL, OCTISALATE, OXYBENZONE (BENZOPHENONE-3)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		RETINYL PALMITATE, UREA
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)		LIMONENE, LINALOOL, ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BENZYL CINNAMATE, BENZYL SALICYLATE, LILIAL, CINNAMYL ALCOHOL, CITRAL, CITRONELLOL, COUMARIN, EUGENOL, EVERNIA FURFURACEA (OAKMOSS LICHEN) EXTRACT, GERANIOL, HEXYL CINNAMAL, HYDROXYCITRONELLAL, ISOEUGENOL, LYRAL, BENZYL ALCOHOL, DIMETHICONE, EXT D&C VIOLET 2
Determined safe for use in cosmetics, subject to concentration or use limitations - any		D&C RED 28 ALUMINUM LAKE, D&C RED 30 LAKE, D&C RED 6 LAKE, D&C RED 7 LAKE, ACRYLATES COPOLYMER, ALOE BARBADENSIS (ALOE VERA) GEL, AMINOMETHYL PROPANOL, BENZYL ALCOHOL, CETEARETH-20, EXT D&C VIOLET 2, LAURYL PEG/ PPG-18/ 18 METHICONE, LECITHIN, PEG-8, PROPYLENE GLYCOL, SODIUM PCA, TRIDECYL SALICYLATE, TRIETHANOLAMINE, CAPSICUM FRUTESCENS, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		BENZYL ALCOHOL, D&C RED 27 LAKE, D&C RED 28 ALUMINUM LAKE, D&C RED 30 LAKE, D&C RED 7 LAKE, D&C YELLOW 5 ALUMINUM LAKE, D&C YELLOW 6 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, FD&C YELLOW 5 ALUMINUM LAKE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		FD&C YELLOW 5, SODIUM HYDROXIDE, STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		ASPARTIC ACID, BHT, DISODIUM EDTA, EUGENOL
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at moderate doses		AMINOMETHYL PROPANOL, LILIAL, CETEARETH-20, CITRONELLOL, COUMARIN, FERRIC FERROCYANIDE, GERANIOL, GLUCOSE, GLUTAMIC ACID, ISOEUGENOL, LECITHIN, LINALOOL, MENTHOL, METHYLPARABEN, PHENOXYETHANOL, UREA
One or more animal studies show brain and nervous system effects at high doses		BENZYL CINNAMATE, BUTYLENE GLYCOL, CITRAL, FD&C BLUE 1, FD&C YELLOW 6, FRUCTOSE, GLYCERIN, HEXYL CINNAMAL, OXYBENZONE (BENZOPHENONE-3), POTASSIUM SORBATE, PROPYLENE GLYCOL, RETINYL PALMITATE, SODIUM DEHYDROACETATE, ULTRAMARINES, POLOXAMER 407, SODIUM CHONDROITIN SULFATE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		HEXYLENE GLYCOL, SD ALCOHOL 1

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BENZOPHENONE-2, BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN
One or more animal studies show endocrine system disruption at high doses		ALCOHOL DENATURED, BHT, BUTYLENE GLYCOL, CYCLOHEXASILOXANE, DISODIUM EDTA, GLYCERIN, HEXYLENE GLYCOL, PVP, SODIUM PCA, TRIETHANOLAMINE, SODIUM CHONDROITIN SULFATE
Associated with endocrine disruption		BENZYL BENZOATE, BENZYL SALICYLATE, LILIAL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZYL SALICYLATE, BHT, CINNAMYL ALCOHOL, CITRAL, COUMARIN, LIMONENE, EUGENOL, EVERNIA FURFURACEA (OAKMOSS LICHEN) EXTRACT, FRAGRANCE, GERANIOL, HEXYLENE GLYCOL, HYDROXYCITRONELLAL, ISOEUGENOL, LYRAL, TRIETHANOLAMINE
Possible human immune system toxicant		ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BENZYL CINNAMATE, LILIAL, CITRONELLOL, HEXYL CINNAMAL, LINALOOL, OXYBENZONE (BENZOPHENONE-3)
Human immune and respiratory toxicant - strong evidence	AND products that may be aerosolized (airborne)	LECITHIN
Human immune system toxicant - strong evidence	products that may be aerosolized (airborne)	SILICA, POLOXAMER 407
Human skin toxicant - strong evidence		BENZOPHENONE-2, BUTYLPARABEN, ETHYLPARABEN, EXT D&C VIOLET 2, ISOBUTYLPARABEN, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of immune system toxicity		ZINC STEARATE, PROPYLENE GLYCOL
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more human case studies show possible allergenic effects		BENZYL ALCOHOL, OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL
One or more animal studies show gastrointestinal effects at moderate doses		MICA
Associated with immunotoxicity		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE)

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife and humans	products that may be aerosolized (airborne)	SILICA
Persistent, bioaccumulative in wildlife and humans		MICA, IRON OXIDES
Persistent, bioaccumulative in wildlife		CHROMIUM HYDROXIDE GREEN, CYCLOHEXASILOXANE, CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C RED 30 LAKE, DISODIUM EDTA-COPPER, ZINC STEARATE, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		ALANINE, ALPHA-ISOMETHYL IONONE, AMINOMETHYL PROPANOL, ASCORBIC ACID (VITAMIN C), ASCORBYL PALMITATE (VITAMIN C PALMITATE), ASPARTIC ACID, BENZOPHENONE-2, BENZYL BENZOATE, BENZYL CINNAMATE, BENZYL SALICYLATE, BUTYLENE GLYCOL, BUTYLPARABEN, C18-36 ACID TRIGLYCERIDE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CAPRYLYL GLYCOL, CARMINE, CETEARETH-20, CETEARYL ALCOHOL, CINNAMYL ALCOHOL, CITRAL, CITRONELLOL, COUMARIN, D&C YELLOW 10, DIETHYLHEXYL SEBACATE, DIMETHICONE, LIMONENE, DISODIUM EDTA, ETHYLPARABEN, FD&C RED 4, FD&C YELLOW 6, FRUCTOSE, GERANIOL, GLUCOSE, GLUTAMIC ACID, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, HEXYL CINNAMAL, HEXYLENE GLYCOL, HYDROXYCITRONELLAL, ISOBUTYLPARABEN, ISOEUGENOL, LECITHIN, LINALOOL, LYRAL, MENTHOL, METHYLPARABEN, OCTISALATE, PHENOXYETHANOL, POTASSIUM SORBATE, PROPYLPARABEN, RETINYL PALMITATE, SODIUM DEHYDROACETATE, SODIUM PCA, SODIUM STEARATE, SORBITOL, SQUALANE, STEARIC ACID, SUCROSE, SYNTHETIC BEESWAX, TRISODIUM EDTA, UREA, OLETH-20, PEG-100 STEARATE
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), BISMUTH OXYCHLORIDE, LILIAL, CARBOMER, D&C RED 6, D&C RED 7, D&C RED 7 LAKE, D&C YELLOW 6 ALUMINUM LAKE, DICALCIUM PHOSPHATE, EXT D&C VIOLET 2, FD&C BLUE 1, FD&C YELLOW 5, FERRIC FERROCYANIDE, NYLON-12, PHENYL TRIMETHICONE, SODIUM CHLORIDE, TOCOPHEROL, TOCOPHERYL ACETATE, WATER, CI 77491
Not suspected to be bioaccumulative		ALCOHOL DENATURED, CHROMIUM OXIDE GREENS, PVP, SODIUM HYDROXIDE, TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, POLOXAMER 407, POLYBUTENE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN, FERRIC FERROCYANIDE
Known human respiratory toxicant	products that may be aerosolized (airborne)	SILICA
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		TRIETHANOLAMINE, MICA
One or more animal studies show cardiovascular effects at very low doses		GLUTAMIC ACID, GLYCERIN, SODIUM HYDROXIDE, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	EUGENOL, STEARIC ACID, TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ALCOHOL DENATURED, HEXYLENE GLYCOL, HYDROXYCITRONELLAL, MENTHOL, PHENOXYETHANOL, SODIUM LAURETH-12 SULFATE
One or more animal studies show broad systemic effects at low doses		COUMARIN, DISODIUM EDTA, GERANIOL, POLOXAMER 407,
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT, CI 77491
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	BENZOPHENONE-2, CETEARETH-20, CITRONELLOL, LINALOOL, SODIUM CHLORIDE, OLETH-20
Classified as toxic or harmful	products for use around the mouth; products for use on the lips	SODIUM DEHYDROACETATE
Classified as toxic or harmful	products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne)	BENZYL ALCOHOL
Limited evidence of any toxicity	products that may be aerosolized (airborne)	D&C RED 27 LAKE, D&C RED 30 LAKE, D&C RED 7 LAKE, D&C YELLOW 5 ALUMINUM LAKE, D&C YELLOW 6 ALUMINUM LAKE, ZINC STEARATE
Limited evidence of any toxicity		D&C RED 28 ALUMINUM LAKE, FD&C BLUE 1 ALUMINUM LAKE, FD&C YELLOW 5 ALUMINUM LAKE, SD ALCOHOL 1
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	DISODIUM EDTA-COPPER
Limited evidence of sense organ toxicity		BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, LAURYL PEG/ PPG-18/ 18 METHICONE, PEG-8, PROPYLPARABEN, PEG-100 STEARATE, RETINYL PALMITATE
One or more animal studies show blood effects at moderate doses (low dose studies may be unavailable for this ingredient)		FRUCTOSE, ALOE BARBADENSIS (ALOE VERA) GEL, CHROMIUM OXIDE GREENS, CITRAL, DIETHYLHEXYL SEBACATE, GLYCERYL MONOSTEARATE, ISOEUGENOL, OCTISALATE, POLYSORBATE-60, POTASSIUM SORBATE, PVP, SODIUM STEARATE, TOCOPHERYL ACETATE,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3), FD&C BLUE 1
One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient)		TRISODIUM EDTA,
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	AMINOMETHYL PROPANOL, LILIAL, UREA
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL, CETYL ALCOHOL, CYCLOMETHICONE, CYCLOPENTASILOXANE, LYRAL, PARAFFIN, SYNTHETIC BEESWAX
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ASCORBYL PALMITATE (VITAMIN C PALMITATE), ASPARTIC ACID, BENZYL SALICYLATE, BISMUTH OXYCHLORIDE, CINNAMYL ALCOHOL, D&C YELLOW 10, LIMONENE, HEXYL CINNAMAL, SODIUM PCA, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE, BENZYL CINNAMATE, FD&C YELLOW 6, SORBITOL, SODIUM CHONDROITIN SULFATE, ULTRAMARINES, CYCLOHEXASILOXANE,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	GLUCOSE
One or more animal studies show no adverse any effects at high doses		CHROMIUM HYDROXIDE GREEN
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as expected to be toxic or harmful		POLYBUTENE
Classified as not expected to be potentially toxic or harmful		ALANINE, ALPHA-ISOMETHYL IONONE, ASCORBIC ACID (VITAMIN C), AVOBENZONE (PARSOL 1789 \| BUTYL METHOXYDIBENZOYLMETHANE), BENZYL BENZOATE, BUTYROSPERMUM PARKII (SHEA BUTTER), C18-36 ACID TRIGLYCERIDE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CAPRYLYL GLYCOL, CARBOMER, CARMINE, COPERNICIA CERIFERA (CARNAUBA) WAX, CETEARYL ALCOHOL, D&C RED 6, D&C RED 7, DEXTRIN, DICALCIUM PHOSPHATE, EXT D&C VIOLET 2, FD&C RED 4, GLYCERYL STEARATE SE, LECITHIN, NYLON-12, PHENYL TRIMETHICONE, SQUALANE, SUCROSE, IRON OXIDES, THEOBROMA CACAO (CACAO) SEED BUTTER, TOCOPHEROL, WATER, XANTHAN GUM, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Prohibited for use in food		COUMARIN
Occupational hazards related to handling		ALCOHOL DENATURED, LIMONENE, SODIUM HYDROXIDE, SD ALCOHOL 1

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED, LECITHIN, MENTHOL, ULTRAMARINES, SD ALCOHOL 1
Designated as safe for general or specific, limited use in food	products that may be aerosolized (airborne)	SILICA
Designated as safe for general or specific, limited use in food		ALANINE, ALCOHOL DENATURED, ALOE BARBADENSIS (ALOE VERA) GEL, ALPHA-ISOMETHYL IONONE, ASCORBIC ACID (VITAMIN C), ASCORBYL PALMITATE (VITAMIN C PALMITATE), ASPARTIC ACID, BENZYL ALCOHOL, BENZYL BENZOATE, BENZYL CINNAMATE, BENZYL SALICYLATE, BHT, BUTYLENE GLYCOL, BUTYLPARABEN, CARMINE, COPERNICIA CERIFERA (CARNAUBA) WAX, CETYL ALCOHOL, CINNAMYL ALCOHOL, CITRAL, CITRONELLOL, D&C YELLOW 5 ALUMINUM LAKE, D&C YELLOW 6 ALUMINUM LAKE, DEXTRIN, DICALCIUM PHOSPHATE, DIMETHICONE, LIMONENE, DISODIUM EDTA, EUGENOL, FD&C BLUE 1, FD&C BLUE 1 ALUMINUM LAKE, FD&C YELLOW 5, FD&C YELLOW 6, FRUCTOSE, GERANIOL, GLUCOSE, GLUTAMIC ACID, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, HEXYL CINNAMAL, HYDROXYCITRONELLAL, ISOEUGENOL, LAURYL PEG/ PPG-18/ 18 METHICONE, LECITHIN, LINALOOL, MENTHOL, METHYLPARABEN, PARAFFIN, PEG-8, POLYSORBATE-60, POTASSIUM SORBATE, PROPYLENE GLYCOL, PROPYLPARABEN, PVP, RETINYL PALMITATE, SODIUM CHLORIDE, SODIUM DEHYDROACETATE, SODIUM HYDROXIDE, SODIUM STEARATE, SORBITOL, STEARIC ACID, IRON OXIDES, TETRASODIUM EDTA, THEOBROMA CACAO (CACAO) SEED BUTTER, TITANIUM DIOXIDE (NON-NANO), TOCOPHEROL, TOCOPHERYL ACETATE, TRIETHANOLAMINE, UREA, XANTHAN GUM, ZINC STEARATE, CI 77491, PEG-100 STEARATE, POLOXAMER 407

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		AMINOMETHYL PROPANOL, CITRAL, LIMONENE, HEXYLENE GLYCOL, PHENOXYETHANOL, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL, LAURETH-4, POLYBUTENE, SODIUM LAURETH-12 SULFATE
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, CITRONELLOL, EUGENOL, GERANIOL, HEXYL CINNAMAL, ISOEUGENOL, LINALOOL, SODIUM HYDROXIDE, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, BENZYL ALCOHOL, BHT, LILIAL, CETEARETH-20, CINNAMYL ALCOHOL, HYDROXYCITRONELLAL, METHYLPARABEN, OCTISALATE, SQUALANE, STEARIC ACID, SYNTHETIC BEESWAX, TETRASODIUM EDTA, UREA, OLETH-20
One or more animal studies show skin irritation at moderate doses		BENZYL CINNAMATE, BUTYLPARABEN, CYCLOMETHICONE, CYCLOPENTASILOXANE, GLYCERIN, LYRAL, MENTHOL, PARAFFIN, SODIUM CHLORIDE
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		CI 77491
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), BENZYL ALCOHOL, BENZYL BENZOATE, PHENOXYETHANOL, SODIUM DEHYDROACETATE, TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		BHT, CHROMIUM OXIDE GREENS, FERRIC FERROCYANIDE, MICA, PARAFFIN
Allowed workplace exposures restricted to moderate doses		GLYCERIN, SODIUM STEARATE, SUCROSE, TRIETHANOLAMINE, ZINC STEARATE
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		GLUTAMIC ACID, SILICA,
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT, CI 77491
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		COUMARIN, FRUCTOSE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, ASPARTIC ACID, BENZOPHENONE-2, CINNAMYL ALCOHOL, CITRAL, CYCLOMETHICONE, CYCLOPENTASILOXANE, GLUCOSE, GLYCERIN, ISOEUGENOL, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE