Dark & Lovely || Skin Deep: Cosmetic Safety Reviews

BRAND: Dark & Lovely

Manufacturer: L'Oréal

BRAND SUMMARY

product score range	7	to	10
product count	69 (browse)
ingredient count	113
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 69 products by Dark & Lovely

Product type(s) by this brand in Skin Deep: hair color and bleaching (6), hair relaxer (1), styling gel/lotion (1)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	6 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
P-PHENYLENEDIAMINE	10	52%	5 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	10	52%	4 products	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-AMINOPHENOL	8	57%	3 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
OXYBENZONE (BENZOPHENONE-3)	9	55%	2 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	8 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	5 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
SILICA	1	69%	1 products	Biochemical or cellular level changes
ETHANOLAMINE	7	66%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BUTYLPARABEN	6	79%	6 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
DIMETHICONE PEG-7 COCOATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-2 OLEAMINE	4	75%	5 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	5 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-75 LANOLIN	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
EXT D&C VIOLET 2	5	73%	5 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
SODIUM METABISULFITE	6	70%	5 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROGEN PEROXIDE	3	65%	5 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
M-AMINOPHENOL	6	65%	2 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
LILIAL	5	64%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
BENZYL SALICYLATE	6	62%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
LYRAL	5	62%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
P-METHYLAMINOPHENOL SULFATE	5	60%	1 products	Cancer, Allergies/immunotoxicity, Occupational hazards
LIMONENE	6	56%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
ETHYLPARABEN	5	80%	6 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ALCOHOL DENATURED	5	71%	5 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	6 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PHENYL METHYL PYRAZOLONE	5	68%	5 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
4-AMINO-2-HYDROXYTOLUENE	5	67%	2 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
HEXYLENE GLYCOL	4	67%	5 products	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
COCAMIDOPROPYL BETAINE	5	63%	6 products	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
HYDROLYZED RICE PROTEIN	4	99%	5 products	Contamination concerns (GOSSYPOL, HEAVY METALS, ORGANOCHLORINES, PESTICIDES)
SODIUM LAURETH SULFATE	4	88%	6 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-20	3	87%	1 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TITANIUM DIOXIDE (NON-NANO)	1	81%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	6 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
COCAMIDE MEA	2	75%	6 products	Contamination concerns (NITROSAMINES)
D&C RED 33	1	75%	1 products	none identified
ORYZA SATIVA (RICE) BRAN OIL	4	74%	5 products	Contamination concerns (GOSSYPOL, HEAVY METALS, ORGANOCHLORINES, PESTICIDES)
FD&C RED 4	1	73%	1 products	none identified
MINERAL OIL	2	73%	8 products	Organ system toxicity (non-reproductive), Occupational hazards
LANOLIN	4	71%	2 products	Allergies/immunotoxicity
ALPHA-ISOMETHYL IONONE	4	68%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
6-HYDROXYINDOLE	3	67%	3 products	Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PHENOXYETHANOL	4	67%	8 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HEXYL CINNAMAL	4	65%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
PROPYLENE GLYCOL	4	60%	8 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
ISOBUTYLPARABEN	3	83%	6 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
CI 15510	2	83%	1 products	Developmental/reproductive toxicity
FD&C YELLOW 5	2	82%	3 products	Neurotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	6 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
CHLOROXYLENOL	3	74%	2 products	Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DIMETHICONE	2	74%	2 products	Violations, restrictions & warnings
CITRIC ACID	2	72%	6 products	Violations, restrictions & warnings
PETROLATUM	2	94%	3 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
POLYQUATERNIUM-7	2	93%	6 products	Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
PANTHENOL	2	88%	8 products	Multiple, additive exposure sources
POLYQUATERNIUM-6	2	87%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
CALCIUM HYDROXIDE	1	83%	1 products	Occupational hazards
FD&C BLUE 1	1	83%	1 products	none identified
AMMONIUM ACETATE	2	82%	5 products	none identified
OLEIC ACID	1	82%	5 products	Irritation (skin, eyes, or lungs)
SUCCINIC ACID	2	82%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive)
TETRASODIUM PYROPHOSPHATE	2	82%	5 products	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
AMMONIUM HYDROXIDE	2	81%	5 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CHOLESTEROL	2	74%	5 products	Persistence and bioaccumulation
GLYCERIN	2	74%	7 products	Organ system toxicity (non-reproductive), Occupational hazards
SODIUM PCA	2	71%	3 products	Contamination concerns (NITROSAMINES)
POLYQUATERNIUM-37	0	94%	7 products	none identified
CETEARYL ALCOHOL	0	93%	8 products	none identified
DENATONIUM BENZOATE	1	90%	1 products	none identified
DICETYLDIMONIUM CHLORIDE	1	90%	5 products	none identified
PROPYLENE GLYCOL DICAPRYLATE	0	90%	1 products	Enhanced skin absorption
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE	0	90%	5 products	Enhanced skin absorption
COCOS NUCIFERA (COCONUT) OIL	1	89%	1 products	none identified
DICAPRYLYL MALEATE	1	89%	1 products	none identified
GUANIDINE CARBONATE	1	89%	1 products	Organ system toxicity (non-reproductive)
STEARETH-21	1	89%	2 products	none identified
OLEA EUROPAEA (OLIVE) OIL	1	88%	2 products	Irritation (skin, eyes, or lungs)
PHENOLSULFONPHTHALEIN	1	88%	1 products	Organ system toxicity (non-reproductive)
SODIUM STANNATE	1	88%	5 products	Occupational hazards
SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX	1	88%	1 products	none identified
STEARETH-2	1	88%	2 products	none identified
ERYTHORBIC ACID	1	87%	5 products	none identified
GLYCOL STEARATE	1	87%	5 products	none identified
OLEYL ALCOHOL	1	87%	5 products	Irritation (skin, eyes, or lungs)
PERSEA GRATISSIMA (AVOCADO) OIL	1	87%	2 products	Irritation (skin, eyes, or lungs)
SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL	1	87%	2 products	none identified
ISOPROPYL MYRISTATE	1	86%	1 products	Irritation (skin, eyes, or lungs)
POTASSIUM SORBATE	1	85%	6 products	none identified
POLYSORBATE-20	1	84%	6 products	none identified
2,4-DIAMINOPHENOXYETHANOL HCL	1	75%	2 products	Cancer
PENTASODIUM PENTETATE	0	74%	5 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	5 products	none identified
BEHENTRIMONIUM METHOSULFATE	0	100%	1 products	none identified
BIS-P-PHENYLENEDIAMINE SULFATE	0	100%	2 products	none identified
DICAPRYLATE/ DICAPRATE	0	100%	1 products	none identified
HYDROXYPROPYLTRIMONIUM HONEY	0	100%	3 products	none identified
POLYGLYCERYL-2 OLEYL ETHER	0	100%	5 products	none identified
POLYGLYCERYL-4 OLEYL ETHER	0	100%	5 products	none identified
POLYQUATERNIUM-22	0	100%	1 products	none identified
POLYQUATERNIUM-39	0	100%	2 products	none identified
POLYQUATERNIUM-47	0	100%	5 products	none identified
PPG-1 TRIDECETH-6	0	100%	7 products	none identified
SILYBUM MARIANUM (BLESSED THISTLE) ETHYL ESTER	0	100%	1 products	none identified
SODIUM DIETHYLAMINOPROPYL COCOASPARTAMIDE	0	100%	5 products	none identified
TRIDECETH-2 CARBOXAMIDE MEA	0	100%	5 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER)	0	94%	2 products	none identified
HYDROGENATED STYRENE/ ISOPRENE COPOLYMER	0	94%	1 products	none identified
HYDROGENATED STYRENE/BUTADIENE COPOLYMER	0	94%	1 products	none identified
POLYQUATERNIUM-10	0	93%	5 products	none identified
PROPYLENE GLYCOL DICAPRATE	0	90%	1 products	Enhanced skin absorption
WATER	0	0%	8 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Cancer - not classifiable/not likely to be human carcinogen	products that may be aerosolized (airborne)	SILICA
Cancer - not classifiable/not likely to be human carcinogen		CHOLESTEROL, LIMONENE, FD&C BLUE 1, FD&C RED 4, HYDROGEN PEROXIDE, P-PHENYLENEDIAMINE, RESORCINOL
Mutagen - limited evidence		P-AMINOPHENOL
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		2,4-DIAMINOPHENOXYETHANOL HCL, 4-AMINO-2-HYDROXYTOLUENE, 6-HYDROXYINDOLE, ALCOHOL DENATURED, EXT D&C VIOLET 2, M-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, PHENYL METHYL PYRAZOLONE
Cancer - not classifiable/not likely to be human carcinogen		AMMONIUM ACETATE
One or more in vitro tests on mammalian cells show positive mutation results		BUTYLPARABEN, CALCIUM HYDROXIDE, DISODIUM EDTA, ERYTHORBIC ACID, ETHANOLAMINE, ETHYLPARABEN, FD&C YELLOW 5, GLYCERIN, METHYLPARABEN, OLEIC ACID, POTASSIUM SORBATE, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM METABISULFITE, SUCCINIC ACID, TOCOPHERYL ACETATE, CI 15510
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE, CHLOROXYLENOL, D&C RED 33, LINALOOL, OLEA EUROPAEA (OLIVE) OIL, OXYBENZONE (BENZOPHENONE-3), PHENOLSULFONPHTHALEIN, PHENOXYETHANOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human nervous system toxicant - moderate evidence		P-PHENYLENEDIAMINE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		CI 15510
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3), ALCOHOL DENATURED
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		CHOLESTEROL, DICETYLDIMONIUM CHLORIDE, GLYCERIN, P-AMINOPHENOL, PROPYLENE GLYCOL
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at high doses		LILIAL, DISODIUM EDTA, ETHANOLAMINE, ETHYLPARABEN, FD&C YELLOW 5, M-AMINOPHENOL, PHENYL METHYL PYRAZOLONE, POLYSORBATE-20, SODIUM METABISULFITE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Banned or found unsafe for use in cosmetics	product not intended as hair dye/bleach	HYDROGEN PEROXIDE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	products for use around the mouth, lips, eyes, or on damaged skin	EXT D&C VIOLET 2, FD&C RED 4
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C RED 33
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	products that may be aerosolized (airborne)	COCAMIDE MEA
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-30, DIMETHICONE PEG-7 COCOATE, PEG-2 OLEAMINE, PEG-40 HYDROGENATED CASTOR OIL, PEG-75 LANOLIN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed off	products that are intended to be left on the skin	ETHANOLAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL, RESORCINOL, OXYBENZONE (BENZOPHENONE-3), CITRIC ACID, P-PHENYLENEDIAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics	products for use on the lips	HYDROGEN PEROXIDE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)		LIMONENE, LINALOOL, ALPHA-ISOMETHYL IONONE, BENZYL SALICYLATE, LILIAL, HEXYL CINNAMAL, LYRAL, 4-AMINO-2-HYDROXYTOLUENE, DIMETHICONE, EXT D&C VIOLET 2, M-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE
Determined safe for use in cosmetics, subject to concentration or use limitations - any		2,4-DIAMINOPHENOXYETHANOL HCL, 4-AMINO-2-HYDROXYTOLUENE, 6-HYDROXYINDOLE, M-AMINOPHENOL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, RESORCINOL, D&C RED 33
Determined safe for use in cosmetics, subject to concentration or use limitations - Determined safe for use when formulated to avoid irritation, in assessment by industry safety panel (Cosmetic Ingredient Review, CIR)	products for use on damaged skin or infants	PENTASODIUM PENTETATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel		ORYZA SATIVA (RICE) BRAN OIL, ALOE BARBADENSIS (ALOE VERA) GEL, CETEARETH-30, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, DIMETHICONE PEG-7 COCOATE, ETHANOLAMINE, EXT D&C VIOLET 2, PEG-2 OLEAMINE, PEG-40 HYDROGENATED CASTOR OIL, PROPYLENE GLYCOL, SODIUM PCA, PEG-75 LANOLIN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		FD&C YELLOW 5, HYDROGEN PEROXIDE, SUCCINIC ACID
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA, TETRASODIUM PYROPHOSPHATE
One or more animal studies show brain and nervous system effects at moderate doses		AMMONIUM ACETATE, LILIAL, CETEARETH-30, DENATONIUM BENZOATE, ETHANOLAMINE, LINALOOL, M-AMINOPHENOL, METHYLPARABEN, OLEIC ACID, P-AMINOPHENOL, PHENOXYETHANOL, POLYQUATERNIUM-6, RESORCINOL, SODIUM METABISULFITE
One or more animal studies show brain and nervous system effects at high doses		4-AMINO-2-HYDROXYTOLUENE, CHOLESTEROL, FD&C BLUE 1, GLYCERIN, HEXYL CINNAMAL, OXYBENZONE (BENZOPHENONE-3), PHENYL METHYL PYRAZOLONE, POTASSIUM SORBATE, PROPYLENE GLYCOL
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		HEXYLENE GLYCOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, PROPYLPARABEN, RESORCINOL
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show endocrine disruption at moderate doses		AMMONIUM ACETATE, ISOBUTYLPARABEN
One or more animal studies show endocrine system disruption at high doses		4-AMINO-2-HYDROXYTOLUENE, ALCOHOL DENATURED, CHOLESTEROL, DISODIUM EDTA, GLYCERIN, HEXYLENE GLYCOL, HYDROGEN PEROXIDE, P-PHENYLENEDIAMINE, SODIUM PCA, SUCCINIC ACID
Associated with endocrine disruption		BENZYL SALICYLATE, LILIAL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZYL SALICYLATE, COCAMIDOPROPYL BETAINE, LIMONENE, FRAGRANCE, HEXYLENE GLYCOL, LANOLIN, LYRAL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, P-PHENYLENEDIAMINE, RESORCINOL, SODIUM METABISULFITE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Possible human immune system toxicant		ALPHA-ISOMETHYL IONONE, LILIAL, HEXYL CINNAMAL, LINALOOL, OXYBENZONE (BENZOPHENONE-3)
Human immune and respiratory toxicant - strong evidence		ETHANOLAMINE
Human immune system toxicant - strong evidence	products that may be aerosolized (airborne)	SILICA
Human skin toxicant - strong evidence		4-AMINO-2-HYDROXYTOLUENE, BUTYLPARABEN, ETHYLPARABEN, EXT D&C VIOLET 2, ISOBUTYLPARABEN, M-AMINOPHENOL, METHYLPARABEN, PHENYL METHYL PYRAZOLONE, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of immune system toxicity	products for use on skin	6-HYDROXYINDOLE, CHLOROXYLENOL
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife and humans	products that may be aerosolized (airborne)	SILICA
Persistent, bioaccumulative in wildlife		CHLOROXYLENOL, CHOLESTEROL
Ingredient is suspected or measured to accumulate in people		OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		4-AMINO-2-HYDROXYTOLUENE, ALPHA-ISOMETHYL IONONE, AMMONIUM ACETATE, BENZYL SALICYLATE, BUTYLPARABEN, CETEARETH-30, CETEARYL ALCOHOL, CITRIC ACID, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, DENATONIUM BENZOATE, DICAPRYLYL MALEATE, DIMETHICONE, LIMONENE, DISODIUM EDTA, ERYTHORBIC ACID, ETHYLPARABEN, FD&C RED 4, GLYCERIN, GLYCOL STEARATE, GUANIDINE CARBONATE, HEXYL CINNAMAL, HEXYLENE GLYCOL, ISOBUTYLPARABEN, ISOPROPYL MYRISTATE, LANOLIN, LINALOOL, LYRAL, METHYLPARABEN, OLEIC ACID, OLEYL ALCOHOL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, P-PHENYLENEDIAMINE, PANTHENOL, PEG-2 OLEAMINE, PHENOLSULFONPHTHALEIN, PHENOXYETHANOL, PHENYL METHYL PYRAZOLONE, POTASSIUM SORBATE, PROPYLENE GLYCOL DICAPRATE, PROPYLENE GLYCOL DICAPRYLATE, PROPYLPARABEN, SODIUM PCA, SUCCINIC ACID, OLETH-20, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, STEARETH-2, STEARETH-21
Not suspected to be bioaccumulative		LILIAL, CALCIUM HYDROXIDE, COCOS NUCIFERA (COCONUT) OIL, D&C RED 33, EXT D&C VIOLET 2, FD&C BLUE 1, FD&C YELLOW 5, HYDROGENATED STYRENE/ ISOPRENE COPOLYMER, M-AMINOPHENOL, OLEA EUROPAEA (OLIVE) OIL, PENTASODIUM PENTETATE, PERSEA GRATISSIMA (AVOCADO) OIL, POLYQUATERNIUM-37, POLYQUATERNIUM-7, TETRASODIUM PYROPHOSPHATE, TOCOPHERYL ACETATE, WATER, CI 15510, HYDROGENATED STYRENE/BUTADIENE COPOLYMER
Not suspected to be bioaccumulative		ALCOHOL DENATURED, AMMONIUM HYDROXIDE, PETROLATUM, POLYQUATERNIUM-6, SODIUM METABISULFITE, TITANIUM DIOXIDE (NON-NANO)

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN, P-PHENYLENEDIAMINE
Known human respiratory toxicant	products that may be aerosolized (airborne)	SILICA
Limited evidence of eye toxicity	products for use around the eyes	6-HYDROXYINDOLE, SODIUM METABISULFITE
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		ETHANOLAMINE, P-AMINOPHENOL
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, PHENOLSULFONPHTHALEIN, SUCCINIC ACID, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	OLEIC ACID, TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ALCOHOL DENATURED, AMMONIUM HYDROXIDE, CALCIUM HYDROXIDE, CITRIC ACID, HEXYLENE GLYCOL, HYDROGEN PEROXIDE, PHENOXYETHANOL, RESORCINOL, SODIUM LAURETH SULFATE
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, TETRASODIUM PYROPHOSPHATE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CETEARETH-30, CHLOROXYLENOL, GUANIDINE CARBONATE, LINALOOL, M-AMINOPHENOL, MINERAL OIL, OLETH-20
Classified as toxic or harmful	products for use around the mouth; products for use on the lips	P-METHYLAMINOPHENOL SULFATE
Limited evidence of sense organ toxicity		BUTYLPARABEN, DIMETHICONE PEG-7 COCOATE, ETHYLPARABEN, ISOBUTYLPARABEN, PEG-2 OLEAMINE, PEG-40 HYDROGENATED CASTOR OIL, PROPYLPARABEN, PEG-75 LANOLIN
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		4-AMINO-2-HYDROXYTOLUENE, ALOE BARBADENSIS (ALOE VERA) GEL, GLYCOL STEARATE, OLEA EUROPAEA (OLIVE) OIL, POTASSIUM SORBATE, TOCOPHERYL ACETATE, STEARETH-2, STEARETH-21,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3), FD&C BLUE 1
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	AMMONIUM ACETATE, LILIAL, POLYQUATERNIUM-6
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	LYRAL, OLEYL ALCOHOL, PHENYL METHYL PYRAZOLONE
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		BENZYL SALICYLATE, DICAPRYLYL MALEATE, LIMONENE, ERYTHORBIC ACID, HEXYL CINNAMAL, ISOPROPYL MYRISTATE, PANTHENOL, SODIUM PCA, POLYSORBATE-20, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, COCOS NUCIFERA (COCONUT) OIL, CI 15510,
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CHOLESTEROL, PERSEA GRATISSIMA (AVOCADO) OIL
Classified as expected to be toxic or harmful		DIMETHICONE, POLYQUATERNIUM-37, POLYQUATERNIUM-7
Classified as expected to be toxic or harmful		PETROLATUM
Classified as not expected to be potentially toxic or harmful		ALPHA-ISOMETHYL IONONE, BUTYROSPERMUM PARKII (SHEA BUTTER), CETEARYL ALCOHOL, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, D&C RED 33, DENATONIUM BENZOATE, EXT D&C VIOLET 2, FD&C RED 4, HYDROGENATED STYRENE/ ISOPRENE COPOLYMER, LANOLIN, PENTASODIUM PENTETATE, POLYQUATERNIUM-10, PROPYLENE GLYCOL DICAPRATE, PROPYLENE GLYCOL DICAPRYLATE, WATER, ORYZA SATIVA (RICE) BRAN OIL, HYDROGENATED STYRENE/BUTADIENE COPOLYMER, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		ALCOHOL DENATURED, AMMONIUM HYDROXIDE, LIMONENE, ETHANOLAMINE, HYDROGEN PEROXIDE, SODIUM METABISULFITE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED, PANTHENOL
Designated as safe for general or specific, limited use in food	products that may be aerosolized (airborne)	SILICA
Designated as safe for general or specific, limited use in food		ALCOHOL DENATURED, ALOE BARBADENSIS (ALOE VERA) GEL, ALPHA-ISOMETHYL IONONE, AMMONIUM ACETATE, AMMONIUM HYDROXIDE, BENZYL SALICYLATE, BUTYLPARABEN, CALCIUM HYDROXIDE, CITRIC ACID, COCOS NUCIFERA (COCONUT) OIL, DIMETHICONE, DIMETHICONE PEG-7 COCOATE, LIMONENE, DISODIUM EDTA, ERYTHORBIC ACID, ETHANOLAMINE, FD&C BLUE 1, FD&C YELLOW 5, GLYCERIN, HEXYL CINNAMAL, HYDROGEN PEROXIDE, ISOPROPYL MYRISTATE, LANOLIN, LINALOOL, METHYLPARABEN, MINERAL OIL, OLEIC ACID, PEG-2 OLEAMINE, PEG-40 HYDROGENATED CASTOR OIL, PETROLATUM, POLYSORBATE-20, POTASSIUM SORBATE, PROPYLENE GLYCOL, PROPYLPARABEN, RESORCINOL, SODIUM METABISULFITE, SUCCINIC ACID, TETRASODIUM PYROPHOSPHATE, TITANIUM DIOXIDE (NON-NANO), TOCOPHERYL ACETATE, PEG-75 LANOLIN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		6-HYDROXYINDOLE, CHLOROXYLENOL, LIMONENE, HEXYLENE GLYCOL, P-PHENYLENEDIAMINE, PHENOXYETHANOL, RESORCINOL, SODIUM METABISULFITE, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	ISOPROPYL MYRISTATE, OLEYL ALCOHOL, SODIUM LAURETH SULFATE
Human skin irritant - moderate evidence		AMMONIUM HYDROXIDE, ETHANOLAMINE, HYDROGEN PEROXIDE
One or more animal studies show skin irritation at very low doses		HEXYL CINNAMAL, LINALOOL, PERSEA GRATISSIMA (AVOCADO) OIL
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, LILIAL, CETEARETH-30, METHYLPARABEN, OLEA EUROPAEA (OLIVE) OIL, OLEIC ACID, OLETH-20
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN, CITRIC ACID, GLYCERIN, GLYCOL STEARATE, LYRAL, M-AMINOPHENOL, MINERAL OIL, P-AMINOPHENOL, POLYSORBATE-20
One or more animal studies show skin irritation at high doses		4-AMINO-2-HYDROXYTOLUENE, CHOLESTEROL, P-METHYLAMINOPHENOL SULFATE
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), 6-HYDROXYINDOLE, CHLOROXYLENOL, ETHANOLAMINE, HYDROGEN PEROXIDE, M-AMINOPHENOL, P-AMINOPHENOL, P-METHYLAMINOPHENOL SULFATE, PHENOXYETHANOL, RESORCINOL, SODIUM METABISULFITE
Allowed workplace exposures restricted to low doses		SODIUM STANNATE
Allowed workplace exposures restricted to moderate doses		CALCIUM HYDROXIDE, GLYCERIN, MINERAL OIL, TETRASODIUM PYROPHOSPHATE
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		SILICA,
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL, SODIUM METABISULFITE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, CHOLESTEROL, CITRIC ACID, GLYCERIN, HYDROGEN PEROXIDE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, CI 15510, SIMMONDSIA CHINENSIS (JOJOBA) SEED WAX, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN