Exuviance || Skin Deep: Cosmetic Safety Reviews

BRAND: Exuviance

Manufacturer: NeoStrata

BRAND SUMMARY

product score range	5	to	9
product count	53 (browse)
ingredient count	142
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 53 products by Exuviance

Product type(s) by this brand in Skin Deep: anti-aging (3), around-eye cream (1), facial cleanser (1), facial moisturizer/treatment (3), lip balm (1), mask (1), moisturizer (1), sunscreen: lip balm (1), toners/astringents (3)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	10 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
OCTOXYNOL-11	9	68%	3 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS, ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS)
FRAGRANCE	8	100%	8 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-80 SORBITAN LAURATE	6	70%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
POLYETHYLENE	6	69%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OCTOXYNOL-9	8	68%	1 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (C9 PHENOLS, ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	8	65%	1 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
ZINC OXIDE (Z-COTE, 60nm)	3	74%	1 products	Violations, restrictions & warnings, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
PEG-100 STEARATE	4	69%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TRICLOSAN	7	67%	1 products	Violations, restrictions & warnings, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (CHLOROFORM, DIOXIN)
BUTYLPARABEN	6	79%	1 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
GLYCERYL STEARATE/ PEG-100 STEARATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	6	75%	3 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
LECITHIN	3	70%	1 products	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
BHT	6	61%	1 products	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
DIAZOLIDINYL UREA	6	59%	1 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	4 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHYLPARABEN	5	80%	1 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ALCOHOL DENATURED	5	71%	2 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	5 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	4 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
RETINYL ACETATE	5	67%	1 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
COCAMIDOPROPYL BETAINE	5	63%	1 products	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
SODIUM LAURETH SULFATE	4	88%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ALUMINUM HYDROXIDE	4	86%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO)	1	81%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	5 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
SD ALCOHOL 1	4	77%	1 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
D&C RED 33	4	75%	2 products	Violations, restrictions & warnings
GLYCOLIC ACID	4	70%	2 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
OCTISALATE	3	68%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PHENOXYETHANOL	4	67%	7 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
CHOLECALCIFEROL	4	61%	1 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Occupational hazards
PROPYLENE GLYCOL	4	60%	10 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LAURETH-7	3	100%	2 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
HYDROGENATED PALM KERNEL OIL	3	93%	1 products	Contamination concerns (ORGANOCHLORINES, PCBS, BENZO[A]PYRENE)
AMMONIUM LAURETH SULFATE	3	87%	1 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ISOBUTYLPARABEN	3	83%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5	2	82%	4 products	Neurotoxicity, Organ system toxicity (non-reproductive)
ARGININE	3	79%	5 products	Neurotoxicity, Organ system toxicity (non-reproductive)
DISODIUM EDTA	3	78%	4 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
AMMONIUM CHLORIDE	3	77%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DIMETHICONE	2	74%	7 products	Violations, restrictions & warnings
MENTHA PIPERITA (PEPPERMINT) OIL	3	73%	1 products	Enhanced skin absorption, Contamination concerns (LIMONENE, MENTHOL, MENTHONE)
CITRIC ACID	3	72%	1 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
POLYACRYLAMIDE	3	71%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
PETROLATUM	2	94%	3 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
PANTHENOL	2	88%	2 products	Multiple, additive exposure sources
TOCOPHEROL	2	87%	1 products	Contamination concerns (HYDROQUINONE)
CYCLOMETHICONE	2	83%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
FD&C BLUE 1	1	83%	2 products	none identified
ETHOXYDIGLYCOL	2	82%	4 products	Organ system toxicity (non-reproductive)
AMMONIUM HYDROXIDE	2	81%	5 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CASTOR OIL	2	80%	2 products	Developmental/reproductive toxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PARAFFIN	2	80%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
POLYSORBATE-80	2	80%	3 products	Developmental/reproductive toxicity
ZEA MAYS (CORN) OIL	2	79%	1 products	Neurotoxicity
SODIUM DEHYDROACETATE	2	78%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
GLYCERIN	2	74%	9 products	Organ system toxicity (non-reproductive), Occupational hazards
HYDROGENATED LECITHIN	2	74%	3 products	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
MYRISTIC ACID	2	74%	1 products	Neurotoxicity, Irritation (skin, eyes, or lungs)
STEARIC ACID	2	74%	3 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CHLORPHENESIN	2	72%	8 products	Violations, restrictions & warnings
SODIUM PCA	2	71%	1 products	Contamination concerns (NITROSAMINES)
CITRUS GRANDIS (GRAPEFRUIT) FRUIT EXTRACT	1	100%	2 products	Multiple, additive exposure sources
SYMPHYTUM OFFICINALE (COMFREY) EXTRACT	1	95%	1 products	Organ system toxicity (non-reproductive)
ARACHIDYL ALCOHOL	0	94%	1 products	none identified
C12-15 ALKYL BENZOATE	0	94%	1 products	none identified
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	1 products	none identified
C13-14 ISOPARAFFIN	1	93%	2 products	none identified
CETEARYL ALCOHOL	0	93%	2 products	none identified
GLUCONOLACTONE	1	93%	11 products	none identified
GLYCOL DISTEARATE	1	93%	1 products	Multiple, additive exposure sources
BATYL ALCOHOL	1	93%	1 products	none identified
HYDROXYPROLINE	1	92%	1 products	none identified
SORBITAN STEARATE	1	92%	1 products	none identified
POLYBUTENE	1	92%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OZOKERITE	1	91%	1 products	none identified
ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT	1	90%	1 products	none identified
MANDELIC ACID	1	89%	2 products	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	2 products	none identified
GLYCERYL MONOSTEARATE	1	88%	2 products	none identified
STEARETH-2	1	88%	2 products	none identified
CETYL ALCOHOL	1	87%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DISODIUM COCOAMPHODIACETATE	1	87%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL PALMITATE	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LYSINE	1	87%	1 products	none identified
ARACHIS HYPOGAEA (PEANUT) OIL	1	85%	1 products	Irritation (skin, eyes, or lungs), Enhanced skin absorption
GLYCYRRHIZA GLABRA (LICORICE)	1	85%	1 products	none identified
1-DODECANOL	1	84%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POLYSORBATE-20	1	84%	5 products	none identified
STEARYL ALCOHOL	1	84%	1 products	Irritation (skin, eyes, or lungs)
SODIUM HYALURONATE	1	83%	6 products	none identified
HYDROXYETHYLCELLULOSE	1	82%	3 products	none identified
ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT	1	80%	3 products	Enhanced skin absorption
BUTYLENE GLYCOL	1	79%	7 products	Irritation (skin, eyes, or lungs)
GLYCINE	1	79%	2 products	none identified
POLYVINYL ALCOHOL	1	79%	1 products	none identified
PALMITIC ACID	1	76%	1 products	Neurotoxicity
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT	1	75%	2 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	1 products	none identified
BETA-GLUCAN	0	100%	1 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER) FRUIT	0	100%	1 products	none identified
C12-15 ALKYL ETHYLHEXANOATE	0	100%	1 products	none identified
CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) LEAF EXTRACT	0	100%	1 products	none identified
CAPRYLIC/ CAPRIC/ STEARIC TRIGLYCERIDE	0	100%	1 products	none identified
CHAMOMILLA RECUTITA (MATRICARIA) FLOWER EXTRACT	0	100%	1 products	none identified
CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT	0	100%	3 products	none identified
EUCALYPTUS GLOBULUS (TASMANIAN BLUE GUM) LEAF EXTRACT	0	100%	1 products	none identified
GLUCOHEPTONOLACTONE	0	100%	1 products	none identified
GLYCOSPHINGOLIPIDS	0	100%	1 products	none identified
LACTOBIONIC ACID	0	100%	3 products	none identified
MANGIFERA INDICA (MANGO) SEED OIL	0	100%	1 products	none identified
OCTYLDODECYL BEHENATE	0	100%	1 products	none identified
OCTYLDODECYL MYRISTATE	0	100%	2 products	none identified
CITRUS AURANTIUM DULCIS (ORANGE) PEEL WAX	0	100%	1 products	none identified
PHOSPHATIDYLCHOLINE	0	100%	1 products	none identified
ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT	0	100%	2 products	none identified
TETRAHEXYLDECYL ASCORBATE	0	100%	1 products	none identified
ALGAE	0	100%	3 products	none identified
LAURYL BEHENATE	0	100%	1 products	none identified
LIMNANTHES ALBA (MEADOWFOAM) SEED OIL	0	100%	1 products	none identified
MEADOWFOAM ESTOLIDE	0	100%	1 products	none identified
WHEAT AMINO ACIDS	0	100%	1 products	none identified
CALENDULA OFFICINALIS (POT MARIGOLD) EXTRACT	0	100%	1 products	none identified
MENTHA VIRIDIS (SPEARMINT) LEAF OIL	0	100%	1 products	none identified
METHICONE	0	99%	1 products	none identified
ALEURITES MOLUCCANA (KUKUI) SEED OIL	0	94%	1 products	none identified
ALGAE EXTRACT	0	94%	4 products	none identified
ETHYLHEXYL HYDROXYSTEARATE	0	94%	2 products	none identified
HYDROGENATED VEGETABLE OIL	0	94%	2 products	none identified
MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL	0	94%	1 products	none identified
MENTHYL LACTATE	0	94%	1 products	none identified
PERFLUOROPOLYMETHYLISOPROPYL ETHER	0	94%	1 products	none identified
XANTHAN GUM	0	94%	3 products	none identified
ALTHAEA OFFICINALIS ROOT EXTRACT	0	94%	2 products	none identified
BEESWAX	0	93%	2 products	none identified
HYDROGENATED LANOLIN	0	93%	1 products	none identified
POLYQUATERNIUM-10	0	93%	2 products	none identified
SODIUM CHLORIDE	0	0%	1 products	innocuous
WATER	0	0%	10 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Cancer - not classifiable/not likely to be human carcinogen		BHT, FD&C BLUE 1, POLYETHYLENE, POLYVINYL ALCOHOL, TRIETHANOLAMINE
Not likely to be carcinogenic in humans		MYRISTIC ACID, PALMITIC ACID, STEARIC ACID
Cancer - limited evidence		ALCOHOL DENATURED, RETINYL ACETATE, RETINYL PALMITATE, SD ALCOHOL 1
One or more in vitro tests on mammalian cells show positive mutation results		AMMONIUM CHLORIDE, ARGININE, BUTYLPARABEN, DIAZOLIDINYL UREA, DISODIUM EDTA, ETHYLPARABEN, FD&C YELLOW 5, GLYCERIN, GLYCINE, HYDROXYPROLINE, LYSINE, METHYLPARABEN, OCTOXYNOL-9, POLYSORBATE-80, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM CHLORIDE, SODIUM DEHYDROACETATE, TOCOPHEROL, TOCOPHERYL ACETATE, OCTOXYNOL-11,
One or more in vitro tests on mammalian cells show positive mutation results		ZINC OXIDE (Z-COTE, 60nm)
One or more animal studies show tumor formation at moderate doses		PARAFFIN, PEG-100 STEARATE
One or more in vitro tests non-mammalian cells show positive mutation results		AMMONIUM HYDROXIDE, ARACHIS HYPOGAEA (PEANUT) OIL, D&C RED 33, ETHOXYDIGLYCOL, GLUCONOLACTONE, GLYCYRRHIZA GLABRA (LICORICE), MENTHA PIPERITA (PEPPERMINT) OIL, PHENOXYETHANOL, TRICLOSAN
One or more animal studies show tumor formation at high doses		1-DODECANOL, STEARYL ALCOHOL, ZEA MAYS (CORN) OIL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		CASTOR OIL, SD ALCOHOL 1
Human nervous system toxicant - moderate evidence		ALUMINUM HYDROXIDE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show reproductive effects at very low doses		POLYSORBATE-80
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL ACETATE, RETINYL PALMITATE
Limited evidence of reproductive toxicity		ALCOHOL DENATURED
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		ARGININE, CHOLECALCIFEROL, GLYCERIN, PROPYLENE GLYCOL, SODIUM HYALURONATE,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show developmental effects at high doses		ZINC OXIDE (Z-COTE, 60nm)
One or more animal studies show reproductive effects at high doses		BHT, BUTYLENE GLYCOL, DISODIUM EDTA, ETHOXYDIGLYCOL, ETHYLPARABEN, FD&C YELLOW 5, GLYCOLIC ACID, HYDROXYETHYLCELLULOSE, LYSINE, OCTOXYNOL-9, PEG-80 SORBITAN LAURATE, POLYSORBATE-20, POLYVINYL ALCOHOL, SODIUM DEHYDROACETATE, TRICLOSAN, ZEA MAYS (CORN) OIL, OCTOXYNOL-11, PEG-100 STEARATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C RED 33
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		GLYCOLIC ACID
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-20, GLYCERYL STEARATE/ PEG-100 STEARATE, PEG-40 HYDROGENATED CASTOR OIL, PEG-80 SORBITAN LAURATE, POLYETHYLENE, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any		ZINC OXIDE (Z-COTE, 60nm), PHENOXYETHANOL, CHLORPHENESIN, OCTISALATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CHOLECALCIFEROL, CITRIC ACID, GLYCOLIC ACID, RETINYL ACETATE, RETINYL PALMITATE, TRICLOSAN
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE, OCTOXYNOL-11
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics		D&C RED 33, OCTOXYNOL-9, ALOE BARBADENSIS (ALOE VERA) GEL, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, CETEARETH-20, COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, GLYCERYL STEARATE/ PEG-100 STEARATE, GLYCOLIC ACID, HYDROGENATED LECITHIN, LECITHIN, MENTHA PIPERITA (PEPPERMINT) OIL, PEG-40 HYDROGENATED CASTOR OIL, PEG-80 SORBITAN LAURATE, POLYACRYLAMIDE, POLYETHYLENE, PROPYLENE GLYCOL, SODIUM PCA, TRIETHANOLAMINE, OCTOXYNOL-11, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ALUMINUM HYDROXIDE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		ARGININE, FD&C YELLOW 5, STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		BHT, DISODIUM EDTA, MYRISTIC ACID, PALMITIC ACID, ZEA MAYS (CORN) OIL
One or more animal studies show brain and nervous system effects at moderate doses		AMMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, CETEARETH-20, CHLORPHENESIN, CHOLECALCIFEROL, GLYCOLIC ACID, LECITHIN, GLYCYRRHIZA GLABRA (LICORICE), MENTHA PIPERITA (PEPPERMINT) OIL, METHYLPARABEN, PHENOXYETHANOL, POLYVINYL ALCOHOL, SODIUM HYALURONATE
One or more animal studies show brain and nervous system effects at high doses		BUTYLENE GLYCOL, DIAZOLIDINYL UREA, ETHOXYDIGLYCOL, FD&C BLUE 1, GLYCERIN, GLYCINE, HYDROXYETHYLCELLULOSE, ZINC OXIDE (Z-COTE, 60nm), POLYACRYLAMIDE, POLYETHYLENE, POLYSORBATE-80, PROPYLENE GLYCOL, RETINYL ACETATE, RETINYL PALMITATE, SODIUM DEHYDROACETATE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 1

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN
One or more studies show endocrine disruption at very low doses		TRICLOSAN
Limited evidence of endocrine disruption		OCTOXYNOL-9, OCTOXYNOL-11
One or more animal studies show endocrine disruption at moderate doses		ARGININE, ISOBUTYLPARABEN, GLYCYRRHIZA GLABRA (LICORICE)
One or more animal studies show endocrine system disruption at high doses		ALCOHOL DENATURED, AMMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BHT, BUTYLENE GLYCOL, DIAZOLIDINYL UREA, DISODIUM EDTA, ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT, GLYCERIN, GLYCINE, SODIUM PCA, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BHT, COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, FRAGRANCE, TRIETHANOLAMINE
Human immune and respiratory toxicant - strong evidence		ZINC OXIDE (Z-COTE, 60nm)
Human immune and respiratory toxicant - strong evidence	AND products that may be aerosolized (airborne)	LECITHIN
Human skin toxicant - strong evidence		BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, METHYLPARABEN, OCTOXYNOL-9, PEG-80 SORBITAN LAURATE, PROPYLPARABEN, TOCOPHERYL ACETATE, OCTOXYNOL-11
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human immune system toxicant - moderate evidence		POLYETHYLENE
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more human case studies show possible immune effects		OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE, ZINC OXIDE (Z-COTE, 60nm), TRICLOSAN
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Not suspected to be persistent		AMMONIUM LAURETH SULFATE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, ARACHIDYL ALCOHOL, ARGININE, ASCORBYL PALMITATE (VITAMIN C PALMITATE), BUTYLENE GLYCOL, BUTYLPARABEN, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CASTOR OIL, CETEARETH-20, CETEARYL ALCOHOL, CHLORPHENESIN, CHOLECALCIFEROL, CITRIC ACID, COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, DIMETHICONE, DISODIUM COCOAMPHODIACETATE, DISODIUM EDTA, ETHYLHEXYL HYDROXYSTEARATE, ETHYLPARABEN, GLUCONOLACTONE, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCINE, GLYCOL DISTEARATE, GLYCOLIC ACID, HYDROXYPROLINE, ISOBUTYLPARABEN, ISOPROPYL PALMITATE, LECITHIN, LYSINE, MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL, MANDELIC ACID, MENTHA PIPERITA (PEPPERMINT) OIL, MENTHYL LACTATE, METHYLPARABEN, MYRISTIC ACID, OCTISALATE, PALMITIC ACID, PANTHENOL, PHENOXYETHANOL, POLYVINYL ALCOHOL, PROPYLPARABEN, RETINYL ACETATE, RETINYL PALMITATE, SODIUM DEHYDROACETATE, SODIUM PCA, SORBITAN STEARATE, STEARIC ACID, STEARYL ALCOHOL, PEG-100 STEARATE, STEARETH-2
Not suspected to be persistent		1-DODECANOL, CETYL ALCOHOL, OCTOXYNOL-9, OCTOXYNOL-11
Not suspected to be bioaccumulative		ARACHIS HYPOGAEA (PEANUT) OIL, D&C RED 33, FD&C BLUE 1, FD&C YELLOW 5, HYDROGENATED LANOLIN, HYDROGENATED PALM KERNEL OIL, PERFLUOROPOLYMETHYLISOPROPYL ETHER, POLYETHYLENE, SODIUM CHLORIDE, TOCOPHEROL, TOCOPHERYL ACETATE, WATER, ZEA MAYS (CORN) OIL
Not suspected to be bioaccumulative		ALCOHOL DENATURED, ALUMINUM HYDROXIDE, AMMONIUM CHLORIDE, AMMONIUM HYDROXIDE, PETROLATUM, POLYACRYLAMIDE, TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, POLYBUTENE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Limited evidence of any toxicity		SYMPHYTUM OFFICINALE (COMFREY) EXTRACT
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		POLYETHYLENE, TRIETHANOLAMINE
One or more animal studies show broad systemic effects at very low doses		AMMONIUM CHLORIDE, ARGININE, GLYCERIN, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	STEARIC ACID, TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ALCOHOL DENATURED, AMMONIUM HYDROXIDE, CITRIC ACID, DISODIUM COCOAMPHODIACETATE, GLYCOLIC ACID, PHENOXYETHANOL, SODIUM LAURETH SULFATE
One or more animal studies show broad systemic effects at low doses		ALUMINUM HYDROXIDE, CHOLECALCIFEROL, DISODIUM EDTA, ISOPROPYL PALMITATE, TRICLOSAN, OCTOXYNOL-11,
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CETEARETH-20, ETHOXYDIGLYCOL, OCTOXYNOL-9, SODIUM CHLORIDE
Classified as toxic or harmful	products for use around the mouth; products for use on the lips	SODIUM DEHYDROACETATE
Limited evidence of any toxicity	products that may be aerosolized (airborne)	ZINC OXIDE (Z-COTE, 60nm)
Limited evidence of gastrointestinal or liver toxicity		SD ALCOHOL 1, BUTYLPARABEN, ETHYLPARABEN, GLYCERYL STEARATE/ PEG-100 STEARATE, ISOBUTYLPARABEN, PEG-40 HYDROGENATED CASTOR OIL, PEG-80 SORBITAN LAURATE, PROPYLPARABEN, PEG-100 STEARATE, RETINYL ACETATE, RETINYL PALMITATE
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)		C13-14 ISOPARAFFIN
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		1-DODECANOL, ALOE BARBADENSIS (ALOE VERA) GEL, AMMONIUM LAURETH SULFATE, GLYCERYL MONOSTEARATE, OCTISALATE, TOCOPHERYL ACETATE, BATYL ALCOHOL, STEARETH-2,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCYRRHIZA GLABRA (LICORICE), POLYACRYLAMIDE, ZEA MAYS (CORN) OIL,
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, CHLORPHENESIN, MENTHA PIPERITA (PEPPERMINT) OIL
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL, CASTOR OIL, CETYL ALCOHOL, CYCLOMETHICONE, MYRISTIC ACID, OZOKERITE, PARAFFIN, POLYSORBATE-80, SODIUM HYALURONATE, STEARYL ALCOHOL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ASCORBYL PALMITATE (VITAMIN C PALMITATE), DIAZOLIDINYL UREA, GLYCINE, MANDELIC ACID, PANTHENOL, POLYVINYL ALCOHOL, SODIUM PCA, HYDROXYETHYLCELLULOSE, POLYSORBATE-20,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as expected to be toxic or harmful		PETROLATUM, POLYBUTENE
Classified as not expected to be potentially toxic or harmful		ALEURITES MOLUCCANA (KUKUI) SEED OIL, ALGAE EXTRACT, ARACHIDYL ALCOHOL, ARACHIS HYPOGAEA (PEANUT) OIL, BEESWAX, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CETEARYL ALCOHOL, COCAMIDOPROPYL BETAINE, D&C RED 33, ETHYLHEXYL HYDROXYSTEARATE, GLUCONOLACTONE, GLYCOL DISTEARATE, HYDROGENATED LANOLIN, HYDROGENATED PALM KERNEL OIL, HYDROGENATED VEGETABLE OIL, HYDROXYPROLINE, LECITHIN, LYSINE, MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL, MENTHYL LACTATE, PALMITIC ACID, PERFLUOROPOLYMETHYLISOPROPYL ETHER, POLYQUATERNIUM-10, SORBITAN STEARATE, TOCOPHEROL, WATER, XANTHAN GUM, ALTHAEA OFFICINALIS ROOT EXTRACT

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		ALCOHOL DENATURED, AMMONIUM HYDROXIDE, SD ALCOHOL 1
Occupational hazards related to handling	products for use around the mouth; products for use on the lips; products for use on skin	CHOLECALCIFEROL

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED, GLYCOL DISTEARATE, LECITHIN, OCTOXYNOL-9, PANTHENOL, CITRUS GRANDIS (GRAPEFRUIT) FRUIT EXTRACT, OCTOXYNOL-11, SD ALCOHOL 1
Designated as safe for general or specific, limited use in food		1-DODECANOL, ALCOHOL DENATURED, ALOE BARBADENSIS (ALOE VERA) GEL, ALUMINUM HYDROXIDE, AMMONIUM CHLORIDE, AMMONIUM HYDROXIDE, ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, ARACHIS HYPOGAEA (PEANUT) OIL, ARGININE, ASCORBYL PALMITATE (VITAMIN C PALMITATE), BEESWAX, BHT, BUTYLENE GLYCOL, BUTYLPARABEN, CASTOR OIL, CETYL ALCOHOL, CHOLECALCIFEROL, CITRIC ACID, DIMETHICONE, DISODIUM EDTA, ETHOXYDIGLYCOL, FD&C BLUE 1, FD&C YELLOW 5, GLUCONOLACTONE, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE/ PEG-100 STEARATE, GLYCINE, ISOPROPYL PALMITATE, LECITHIN, GLYCYRRHIZA GLABRA (LICORICE), LYSINE, MENTHA PIPERITA (PEPPERMINT) OIL, MENTHYL LACTATE, METHICONE, METHYLPARABEN, ZINC OXIDE (Z-COTE, 60nm), MYRISTIC ACID, PALMITIC ACID, PARAFFIN, PEG-40 HYDROGENATED CASTOR OIL, PEG-80 SORBITAN LAURATE, PETROLATUM, POLYACRYLAMIDE, POLYETHYLENE, POLYSORBATE-20, POLYSORBATE-80, POLYVINYL ALCOHOL, PROPYLENE GLYCOL, PROPYLPARABEN, RETINYL ACETATE, RETINYL PALMITATE, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, SODIUM CHLORIDE, SODIUM DEHYDROACETATE, SORBITAN STEARATE, STEARIC ACID, STEARYL ALCOHOL, TITANIUM DIOXIDE (NON-NANO), TOCOPHEROL, TOCOPHERYL ACETATE, TRIETHANOLAMINE, XANTHAN GUM, PEG-100 STEARATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		AMMONIUM CHLORIDE, PHENOXYETHANOL, TRICLOSAN, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	AMMONIUM LAURETH SULFATE, BUTYLENE GLYCOL, CASTOR OIL, OCTOXYNOL-9, POLYETHYLENE, SODIUM LAURETH SULFATE, STEARYL ALCOHOL, OCTOXYNOL-11, POLYBUTENE
Human skin irritant - moderate evidence		AMMONIUM HYDROXIDE
One or more animal studies show skin irritation at very low doses		1-DODECANOL, CETYL ALCOHOL, DISODIUM COCOAMPHODIACETATE, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, ARACHIS HYPOGAEA (PEANUT) OIL, BHT, CETEARETH-20, ISOPROPYL PALMITATE, METHYLPARABEN, MYRISTIC ACID, OCTISALATE, STEARIC ACID
One or more animal studies show skin irritation at moderate doses		ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BUTYLPARABEN, CITRIC ACID, CYCLOMETHICONE, ETHOXYDIGLYCOL, GLYCERIN, ZINC OXIDE (Z-COTE, 60nm), OZOKERITE, PALMITIC ACID, PARAFFIN, PEG-80 SORBITAN LAURATE, POLYSORBATE-20, SODIUM CHLORIDE, SODIUM HYALURONATE, SORBITAN STEARATE, ZEA MAYS (CORN) OIL

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		CHOLECALCIFEROL
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), AMMONIUM CHLORIDE, PHENOXYETHANOL, SODIUM DEHYDROACETATE
Allowed workplace exposures restricted to low doses		BHT, ZINC OXIDE (Z-COTE, 60nm), PARAFFIN
Allowed workplace exposures restricted to moderate doses		GLYCERIN, TRIETHANOLAMINE
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
No workplace limits set		GLYCOLIC ACID

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, ARGININE, CITRIC ACID, CYCLOMETHICONE, GLYCERIN, GLYCINE, POLYACRYLAMIDE, POLYETHYLENE, POLYVINYL ALCOHOL, ZEA MAYS (CORN) OIL, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL ACETATE, RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE