Kenneth Cole || Skin Deep: Cosmetic Safety Reviews

BRAND: Kenneth Cole

Manufacturer: Coty, Inc.

BRAND SUMMARY

product score range	5	to	9
product count	30 (browse)
ingredient count	62
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 30 products by Kenneth Cole

Product type(s) by this brand in Skin Deep: after shave (2), antiperspirant/deodorant (1), antiperspirant/deodorant (men's) (2), body spray (1), fragrance for men (2), fragrance for women (2)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	1 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	8 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
PEG-2 DISTEARATE	5	74%	1 products	Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
TRICLOSAN	7	67%	1 products	Violations, restrictions & warnings, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (CHLOROFORM, DIOXIN)
COUMARIN	7	46%	2 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BUTYLPARABEN	6	79%	1 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-8	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 DISTEARATE	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-2 STEARATE	4	74%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
LILIAL	6	64%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BENZYL SALICYLATE	6	62%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity
HYDROXYCITRONELLAL	5	62%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LYRAL	6	62%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity
BHT	6	61%	1 products	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
GERANIOL	6	61%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOEUGENOL	6	59%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
TRIETHANOLAMINE	6	58%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
CITRAL	6	57%	6 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LIMONENE	6	56%	7 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
DIETHYLENE GLYCOL	5	81%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
ETHYLPARABEN	5	80%	1 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ALCOHOL DENATURED	5	71%	3 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	1 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	1 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
BENZYL BENZOATE	5	65%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Occupational hazards
CITRONELLOL	4	65%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
LINALOOL	5	65%	7 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OLETH-20	3	87%	1 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
POLOXAMER 407	2	82%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE	4	81%	1 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
SD ALCOHOL 1	4	77%	3 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
ALPHA-ISOMETHYL IONONE	4	68%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity
PHENOXYETHANOL	4	67%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	3 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
ISOBUTYLPARABEN	3	83%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5	2	82%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE	2	79%	1 products	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SODIUM MYRISTATE	2	92%	2 products	Multiple, additive exposure sources
SODIUM PALMITATE	2	92%	2 products	Multiple, additive exposure sources
SODIUM LAURATE	2	87%	1 products	Multiple, additive exposure sources, Irritation (skin, eyes, or lungs)
TOCOPHEROL	2	87%	1 products	Contamination concerns (HYDROQUINONE)
FD&C BLUE 1	1	83%	1 products	none identified
CYCLOHEXASILOXANE	1	82%	1 products	Persistence and bioaccumulation
TETRASODIUM EDTA	2	81%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
GLYCERIN	2	74%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
POTASSIUM STEARATE	1	85%	1 products	Occupational hazards
SODIUM STEARATE	1	83%	2 products	Occupational hazards
BUTYLENE GLYCOL	1	79%	1 products	Irritation (skin, eyes, or lungs)
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	1 products	none identified
DIMETHICONOL	0	100%	1 products	none identified
MENTHYL PCA	0	100%	1 products	none identified
SODIUM BEHENATE	0	100%	1 products	none identified
SODIUM ARACHIDATE	0	100%	1 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER)	0	94%	1 products	none identified
MENTHYL LACTATE	0	94%	1 products	none identified
VANILLYL BUTYL ETHER	0	94%	1 products	none identified
ETHYL MENTHANE CARBOXAMIDE	0	94%	1 products	none identified
CARBOMER	0	93%	1 products	none identified
WATER	0	0%	8 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - not classifiable/not likely to be human carcinogen		BHT, COUMARIN, LIMONENE, FD&C BLUE 1, TRIETHANOLAMINE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence		ALCOHOL DENATURED, RETINYL PALMITATE, SD ALCOHOL 1
One or more in vitro tests on mammalian cells show positive mutation results		BUTYLPARABEN, DISODIUM EDTA, ETHYLPARABEN, FD&C YELLOW 5, GERANIOL, GLYCERIN, ISOEUGENOL, METHYLPARABEN, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM HYDROXIDE, SODIUM LAURATE, SODIUM MYRISTATE, SODIUM PALMITATE, TOCOPHEROL, TOCOPHERYL ACETATE
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests non-mammalian cells show positive mutation results		LINALOOL, PHENOXYETHANOL, TRICLOSAN
One or more animal studies show tumor formation at high doses		DIETHYLENE GLYCOL, CITRAL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		SD ALCOHOL 1
Human nervous system toxicant - moderate evidence		DIETHYLENE GLYCOL
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of reproductive toxicity		ALCOHOL DENATURED
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, PROPYLENE GLYCOL
One or more animal studies show developmental effects at high doses		LIMONENE
One or more animal studies show reproductive effects at high doses		BHT, BUTYLENE GLYCOL, LILIAL, CITRAL, COUMARIN, DISODIUM EDTA, ETHYLPARABEN, FD&C YELLOW 5, ISOEUGENOL, TRICLOSAN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	PEG-2 STEARATE, PEG-8, PEG-8 DISTEARATE, PEG-2 DISTEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL, RETINYL PALMITATE, TRICLOSAN
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association)		LIMONENE, LINALOOL, ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BENZYL SALICYLATE, LILIAL, CITRAL, CITRONELLOL, COUMARIN, GERANIOL, HYDROXYCITRONELLAL, ISOEUGENOL, LYRAL
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALOE BARBADENSIS (ALOE VERA) GEL, PEG-2 STEARATE, PEG-8, PEG-8 DISTEARATE, PROPYLENE GLYCOL, TRIETHANOLAMINE, PEG-2 DISTEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		DIETHYLENE GLYCOL
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		FD&C YELLOW 5, SODIUM HYDROXIDE, STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		BHT, DISODIUM EDTA
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at moderate doses		LILIAL, CITRONELLOL, COUMARIN, GERANIOL, ISOEUGENOL, LINALOOL, METHYLPARABEN, PHENOXYETHANOL
One or more animal studies show brain and nervous system effects at high doses		BUTYLENE GLYCOL, CITRAL, FD&C BLUE 1, GLYCERIN, PROPYLENE GLYCOL, RETINYL PALMITATE, POLOXAMER 407
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		SD ALCOHOL 1

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, PROPYLPARABEN
One or more studies show endocrine disruption at very low doses		TRICLOSAN
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show endocrine disruption at moderate doses		ISOBUTYLPARABEN
One or more animal studies show endocrine system disruption at high doses		ALCOHOL DENATURED, BHT, BUTYLENE GLYCOL, CYCLOHEXASILOXANE, DISODIUM EDTA, GLYCERIN, TRIETHANOLAMINE
Associated with endocrine disruption		BENZYL BENZOATE, BENZYL SALICYLATE, LILIAL

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZYL SALICYLATE, BHT, CITRAL, COUMARIN, LIMONENE, FRAGRANCE, GERANIOL, HYDROXYCITRONELLAL, ISOEUGENOL, LYRAL, TRIETHANOLAMINE
Possible human immune system toxicant		ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, LILIAL, CITRONELLOL, LINALOOL
Human immune system toxicant - strong evidence	products that may be aerosolized (airborne)	POLOXAMER 407
Human skin toxicant - strong evidence		BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOHEXASILOXANE, CYCLOPENTASILOXANE, TRICLOSAN
Not suspected to be persistent		ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BENZYL SALICYLATE, BUTYLENE GLYCOL, BUTYLPARABEN, CITRAL, CITRONELLOL, COUMARIN, LIMONENE, DISODIUM EDTA, ETHYLPARABEN, GERANIOL, GLYCERIN, HYDROXYCITRONELLAL, ISOBUTYLPARABEN, ISOEUGENOL, LINALOOL, LYRAL, MENTHYL LACTATE, METHYLPARABEN, PEG-2 STEARATE, PHENOXYETHANOL, POTASSIUM STEARATE, PROPYLPARABEN, RETINYL PALMITATE, SODIUM LAURATE, SODIUM MYRISTATE, SODIUM PALMITATE, SODIUM STEARATE, STEARIC ACID, VANILLYL BUTYL ETHER, ETHYL MENTHANE CARBOXAMIDE, OLETH-20, PEG-2 DISTEARATE
Not suspected to be bioaccumulative		LILIAL, CARBOMER, FD&C BLUE 1, FD&C YELLOW 5, TOCOPHEROL, TOCOPHERYL ACETATE, WATER
Not suspected to be bioaccumulative		ALCOHOL DENATURED, SODIUM HYDROXIDE, TRIETHANOLAMINE, POLOXAMER 407

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		TRIETHANOLAMINE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, SODIUM HYDROXIDE, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	STEARIC ACID
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ALCOHOL DENATURED, HYDROXYCITRONELLAL, PHENOXYETHANOL
One or more animal studies show broad systemic effects at low doses		COUMARIN, DISODIUM EDTA, GERANIOL, TRICLOSAN, POLOXAMER 407,
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CITRONELLOL, LINALOOL, OLETH-20
Limited evidence of gastrointestinal or liver toxicity		SD ALCOHOL 1, DIETHYLENE GLYCOL, BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, PEG-2 STEARATE, PEG-8, PEG-8 DISTEARATE, PROPYLPARABEN, PEG-2 DISTEARATE, RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALOE BARBADENSIS (ALOE VERA) GEL, CITRAL, ISOEUGENOL, SODIUM LAURATE, SODIUM STEARATE, TOCOPHERYL ACETATE,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	LILIAL
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL, CYCLOPENTASILOXANE, LYRAL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		BENZYL SALICYLATE, LIMONENE, CYCLOHEXASILOXANE
Classified as not expected to be potentially toxic or harmful		ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BUTYROSPERMUM PARKII (SHEA BUTTER), CARBOMER, MENTHYL LACTATE, POTASSIUM STEARATE, SODIUM MYRISTATE, SODIUM PALMITATE, TOCOPHEROL, VANILLYL BUTYL ETHER, WATER, ETHYL MENTHANE CARBOXAMIDE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Prohibited for use in food		COUMARIN
Occupational hazards related to handling		ALCOHOL DENATURED, LIMONENE, SODIUM HYDROXIDE, SD ALCOHOL 1

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED, SODIUM LAURATE, SODIUM MYRISTATE, SODIUM PALMITATE, PEG-2 DISTEARATE, SD ALCOHOL 1
Designated as safe for general or specific, limited use in food		ALCOHOL DENATURED, ALOE BARBADENSIS (ALOE VERA) GEL, ALPHA-ISOMETHYL IONONE, BENZYL BENZOATE, BENZYL SALICYLATE, BHT, BUTYLENE GLYCOL, BUTYLPARABEN, CITRAL, CITRONELLOL, LIMONENE, DISODIUM EDTA, FD&C BLUE 1, FD&C YELLOW 5, GERANIOL, GLYCERIN, HYDROXYCITRONELLAL, ISOEUGENOL, LINALOOL, MENTHYL LACTATE, METHYLPARABEN, PEG-2 STEARATE, PEG-8, PEG-8 DISTEARATE, POTASSIUM STEARATE, PROPYLENE GLYCOL, PROPYLPARABEN, RETINYL PALMITATE, SODIUM HYDROXIDE, SODIUM LAURATE, SODIUM MYRISTATE, SODIUM PALMITATE, SODIUM STEARATE, STEARIC ACID, TETRASODIUM EDTA, TOCOPHEROL, TOCOPHERYL ACETATE, TRIETHANOLAMINE, VANILLYL BUTYL ETHER, ETHYL MENTHANE CARBOXAMIDE, PEG-2 DISTEARATE, POLOXAMER 407

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		CITRAL, LIMONENE, PHENOXYETHANOL, TRICLOSAN, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL
One or more animal studies show skin irritation at very low doses		CITRONELLOL, GERANIOL, ISOEUGENOL, LINALOOL, SODIUM HYDROXIDE, SODIUM LAURATE, TRIETHANOLAMINE
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, BHT, LILIAL, HYDROXYCITRONELLAL, METHYLPARABEN, STEARIC ACID, TETRASODIUM EDTA, OLETH-20
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN, CYCLOPENTASILOXANE, DIETHYLENE GLYCOL, GLYCERIN, LYRAL, PEG-2 STEARATE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		DIETHYLENE GLYCOL, BENZYL BENZOATE, PHENOXYETHANOL, TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		BHT
Allowed workplace exposures restricted to moderate doses		GLYCERIN, POTASSIUM STEARATE, SODIUM STEARATE, TRIETHANOLAMINE
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		COUMARIN
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, CITRAL, CYCLOPENTASILOXANE, GLYCERIN, ISOEUGENOL, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN