BRAND: Kinerase
Manufacturer: Valeant Pharmaceuticals International
COMPANY POLICIES
Compact for Safe Cosmetics
|
Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| Ingredients used by this brand: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
See all 50 products by Kinerase
Product type(s) by this brand in Skin Deep: acne treatment (1), anti-aging (11), around-eye cream (2), facial cleanser (2), facial moisturizer/treatment (18), lip balm (1), lip plumper (1), mask (1), moisturizer (1), sunscreen: moisturizer (4), sunscreen: SPF 15-30 (5), toners/astringents (1)
ingredients
| score | data gap | products * | concerns | |
| NANO TITANIUM DIOXIDE | 2 | 87% | 3 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| METHYLPARABEN | 10 | 63% | 16 products | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| ETHYLENEDIAMINE | 9 | 56% | 1 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| OXYBENZONE (BENZOPHENONE-3) | 9 | 55% | 5 products | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) | 8 | 65% | 3 products | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| SILICA | 1 | 69% | 3 products | Biochemical or cellular level changes |
| PEG-100 STEARATE | 7 | 69% | 14 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| SALICYLIC ACID | 7 | 66% | 2 products | Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| ALUMINA | 6 | 85% | 3 products | Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Enhanced skin absorption, Occupational hazards |
| BUTYLPARABEN | 6 | 79% | 5 products | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PEG-12 GLYCERYL DISTEARATE | 4 | 76% | 3 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-20 METHYL GLUCOSE | 4 | 76% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-60 ALMOND GLYCERIDES | 4 | 76% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-20 METHYL GLUCOSE SESQUISTEARATE | 4 | 75% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-5 SOYA STEROL | 5 | 75% | 3 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| LECITHIN | 3 | 70% | 1 products | Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES) |
| IODOPROPYNYL BUTYLCARBAMATE | 6 | 65% | 15 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| BHT | 6 | 61% | 1 products | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes |
| COCAMIDE DEA | 6 | 61% | 2 products | Cancer, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES) |
| DIAZOLIDINYL UREA | 6 | 59% | 17 products | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| TRIETHANOLAMINE | 6 | 58% | 14 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| LAURETH-23 | 5 | 83% | 7 products | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| ETHYLPARABEN | 5 | 80% | 5 products | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| PROPYLPARABEN | 5 | 71% | 16 products | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| IMIDAZOLIDINYL UREA | 5 | 70% | 7 products | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| LACTIC ACID | 5 | 70% | 2 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| RETINYL PALMITATE | 5 | 68% | 7 products | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PAPAIN | 5 | 68% | 2 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| COCAMIDOPROPYL BETAINE | 5 | 63% | 2 products | Allergies/immunotoxicity, Contamination concerns (NITROSAMINES) |
| HYDROLYZED RICE BRAN PROTEIN | 4 | 93% | 1 products | Multiple, additive exposure sources, Contamination concerns (GOSSYPOL, HEAVY METALS, PESTICIDES) |
| MAGNESIUM ALUMINUM SILICATE | 4 | 88% | 2 products | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| SODIUM LAURETH SULFATE | 4 | 88% | 2 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| SD ALCOHOL 40C | 4 | 81% | 1 products | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| TOCOPHERYL ACETATE | 4 | 81% | 10 products | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| HOMOSALATE | 4 | 74% | 3 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Enhanced skin absorption, Contamination concerns (SALICYLIC ACID, TRIMETHYLCYCLOHEXANOL) |
| MALIC ACID | 4 | 73% | 1 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ISOPROPYL ALCOHOL | 4 | 72% | 1 products | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| GLYCOLIC ACID | 4 | 70% | 1 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| OCTISALATE | 3 | 68% | 3 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PHENOXYETHANOL | 4 | 67% | 9 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| SODIUM | 4 | 66% | 1 products | Allergies/immunotoxicity |
| CHOLECALCIFEROL | 4 | 61% | 3 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Occupational hazards |
| PROPYLENE GLYCOL | 4 | 60% | 10 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| ISOBUTYLPARABEN | 3 | 83% | 1 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| CYCLOPENTASILOXANE | 2 | 79% | 3 products | Persistence and bioaccumulation |
| DISODIUM EDTA | 3 | 78% | 5 products | Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption |
| TRISODIUM NTA | 3 | 78% | 2 products | Cancer, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs) |
| SODIUM HYDROXIDE | 3 | 77% | 10 products | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CARRAGEENAN | 2 | 75% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (DEGRADED CARRAGEENAN), Biochemical or cellular level changes |
| STYRENE/ ACRYLATES COPOLYMER | 3 | 75% | 3 products | Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE) |
| DIMETHICONE | 2 | 74% | 16 products | Violations, restrictions & warnings |
| GLYCERYL CAPRATE | 3 | 74% | 2 products | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| CITRIC ACID | 3 | 72% | 12 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| SODIUM HEXAMETAPHOSPHATE | 3 | 72% | 3 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (LEAD) |
| OCTOCRYLENE | 3 | 71% | 5 products | Violations, restrictions & warnings, Biochemical or cellular level changes |
| SODIUM LAURYL SULFATE | 3 | 68% | 3 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| PANTHENOL | 2 | 88% | 18 products | Multiple, additive exposure sources |
| TOCOPHEROL | 2 | 87% | 1 products | Contamination concerns (HYDROQUINONE) |
| ETHOXYDIGLYCOL | 2 | 82% | 3 products | Organ system toxicity (non-reproductive) |
| TETRASODIUM EDTA | 2 | 81% | 13 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| POLYSORBATE-80 | 2 | 80% | 2 products | Developmental/reproductive toxicity |
| ZEA MAYS (CORN) OIL | 2 | 79% | 3 products | Neurotoxicity |
| CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT | 2 | 76% | 14 products | Violations, restrictions & warnings |
| CHOLESTEROL | 2 | 74% | 1 products | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | 15 products | Organ system toxicity (non-reproductive), Occupational hazards |
| STEARIC ACID | 2 | 74% | 19 products | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | 2 | 73% | 5 products | Violations, restrictions & warnings, Contamination concerns (BENZOIC ACID, 4-T-BUTYLBENZOIC ACID, BENZALDEHYDE, P-ANISIC ACID, ACETOPHENONE, DIBENZOYLMETHANE) |
| CITRUS AURANTIFOLIA (LIME) OIL | 2 | 73% | 1 products | Violations, restrictions & warnings |
| SODIUM BENZOATE | 2 | 69% | 1 products | Organ system toxicity (non-reproductive) |
| ZEATIN | 1 | 95% | 5 products | none identified |
| C12-15 ALKYL BENZOATE | 0 | 94% | 3 products | none identified |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | 9 products | none identified |
| HEXYLDECANOL | 0 | 94% | 3 products | none identified |
| METHYL GLUCOSE SESQUISTEARATE | 0 | 94% | 2 products | none identified |
| CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT | 1 | 94% | 1 products | Multiple, additive exposure sources |
| SQUALANE | 1 | 93% | 1 products | Irritation (skin, eyes, or lungs) |
| ETHYLHEXYL PALMITATE | 1 | 92% | 2 products | Irritation (skin, eyes, or lungs) |
| SORBITAN STEARATE | 1 | 92% | 3 products | none identified |
| ASCORBIC ACID (VITAMIN C) | 1 | 91% | 11 products | none identified |
| ETHYLHEXYLGLYCERIN | 1 | 90% | 3 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CITRUS AURANTIUM DULCIS (ORANGE) FLOWER OIL | 1 | 89% | 1 products | none identified |
| GLYCERYL MONOSTEARATE | 1 | 88% | 21 products | none identified |
| HYDROLYZED COLLAGEN | 1 | 88% | 1 products | Organ system toxicity (non-reproductive) |
| N6-FURFURYLADENINE | 1 | 88% | 25 products | Organ system toxicity (non-reproductive) |
| SORBITOL | 1 | 88% | 2 products | none identified |
| CETYL ALCOHOL | 1 | 87% | 23 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| GLYCOL STEARATE | 1 | 87% | 2 products | none identified |
| ISOPROPYL PALMITATE | 1 | 87% | 7 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| OLEANOLIC ACID | 1 | 87% | 1 products | none identified |
| SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL | 1 | 87% | 4 products | none identified |
| TROMETHAMINE | 1 | 87% | 11 products | none identified |
| PYRUS COMMUNIS (PEAR) FRUIT EXTRACT | 1 | 87% | 3 products | none identified |
| GLUCOSAMINE HCL | 1 | 86% | 2 products | none identified |
| ISOPROPYL MYRISTATE | 1 | 86% | 2 products | Irritation (skin, eyes, or lungs) |
| TRIBEHENIN | 1 | 86% | 2 products | Enhanced skin absorption |
| TRISODIUM EDTA | 1 | 86% | 1 products | Enhanced skin absorption |
| POTASSIUM SORBATE | 1 | 85% | 2 products | none identified |
| CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL | 1 | 84% | 16 products | none identified |
| STEARYL ALCOHOL | 1 | 84% | 10 products | Irritation (skin, eyes, or lungs) |
| SODIUM HYALURONATE | 1 | 83% | 6 products | none identified |
| GLUCOSE | 1 | 82% | 1 products | none identified |
| HYDROXYETHYLCELLULOSE | 1 | 82% | 1 products | none identified |
| BUTYLENE GLYCOL | 1 | 79% | 2 products | Irritation (skin, eyes, or lungs) |
| ALOE BARBADENSIS (ALOE VERA) GEL | 1 | 72% | 13 products | none identified |
| NORDIHYDROGUAIARETIC ACID | 1 | 65% | 1 products | none identified |
| 1,2-HEXANEDIOL | 0 | 100% | 3 products | none identified |
| ACETYL HEXAPEPTIDE-3 | 0 | 100% | 3 products | none identified |
| ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER | 0 | 100% | 6 products | none identified |
| ALLYL METHACRYLATES CROSSPOLYMER | 0 | 100% | 1 products | none identified |
| AMMONIUM ACRYLOYLDIMETHYL TAURATE/ VP COPOLYMER | 0 | 100% | 3 products | none identified |
| ARTEMISIA VULGARIS (MUGWORT) EXTRACT | 0 | 100% | 1 products | none identified |
| ASCORBYL PHOSPHATE | 0 | 100% | 1 products | none identified |
| BAMBUSA VULGARIS (BAMBOO) EXTRACT | 0 | 100% | 2 products | none identified |
| CERAMIDE 1 | 0 | 100% | 1 products | none identified |
| CERAMIDE 3 | 0 | 100% | 1 products | none identified |
| CERAMIDE 6-II | 0 | 100% | 1 products | none identified |
| CITRUS AURANTIUM DULCIS (ORANGE) PEEL OIL | 0 | 100% | 1 products | none identified |
| CITRUS MEDICA LIMONUM (LEMON) EXTRACT | 0 | 100% | 1 products | none identified |
| COLA ACUMINATA (KOLA) SEED EXTRACT | 0 | 100% | 1 products | none identified |
| EPILOBIUM ANGUSTIFOLIUM (WILLOW HERB) EXTRACT | 0 | 100% | 1 products | none identified |
| ERGOTHIONEINE | 0 | 100% | 4 products | none identified |
| FERULA ASSA-FOETIDA (ASAFETIDA) EXTRACT | 0 | 100% | 3 products | none identified |
| GLYCINE SOJA (SOYBEAN) STEROLS | 0 | 100% | 9 products | none identified |
| HIBISCUS SABDARIFFA (ROSELLE) FLOWER EXTRACT | 0 | 100% | 3 products | none identified |
| LAMINARIA DIGITATA (HORSETAIL KELP) EXTRACT | 0 | 100% | 3 products | none identified |
| MALACHITE EXTRACT | 0 | 100% | 1 products | none identified |
| MONARDA DIDYMA (BERGAMOT) FRUIT OIL | 0 | 100% | 1 products | none identified |
| OXIDO REDUCTASES | 0 | 100% | 1 products | none identified |
| PALMITOYL OLIGOPEPTIDE | 0 | 100% | 2 products | none identified |
| PHYTOSPHINGOSINE | 0 | 100% | 2 products | none identified |
| PLANKTON EXTRACT | 0 | 100% | 1 products | none identified |
| PSEUDOALTEROMONAS FERMENT EXTRACT | 0 | 100% | 1 products | none identified |
| PYRUS MALUS (APPLE) FRUIT EXTRACT | 0 | 100% | 1 products | none identified |
| SACCHARIDE ISOMERATE | 0 | 100% | 3 products | none identified |
| SACCHARUM OFFICINARUM (SUGAR CANE) EXTRACT | 0 | 100% | 1 products | none identified |
| SODIUM CARBOXYMETHYL BETAGLUCAN | 0 | 100% | 6 products | none identified |
| SODIUM LAUROAMPHOACETATE | 0 | 100% | 1 products | none identified |
| SODIUM LAUROYL LACTYLATE | 0 | 100% | 1 products | none identified |
| SOLUBLE COLLAGEN | 0 | 100% | 8 products | none identified |
| BUDDLEJA OFFICINALIS LEAF EXTRACT | 0 | 100% | 1 products | none identified |
| BUTYL AVOCADATE | 0 | 100% | 1 products | none identified |
| EVODIA RUTAECARPA FRUIT EXTRACT | 0 | 100% | 1 products | none identified |
| FERULA FOETIDA ROOT EXTRACT | 0 | 100% | 3 products | none identified |
| LAUROYL ETHYLENEDIAMINE TRIACETIC ACID | 0 | 100% | 1 products | none identified |
| LEMON EKISU | 0 | 100% | 1 products | none identified |
| PISUM SATIVUM (PEA) EXTRACT | 0 | 100% | 2 products | none identified |
| RUMEX OCCIDENTALIS EXTRACT | 0 | 100% | 1 products | none identified |
| PALMITOYL TRIPEPTIDE-3 | 0 | 100% | 2 products | none identified |
| HEXAPEPTIDE-10 | 0 | 100% | 1 products | none identified |
| VANILLA PLANIFOLIA (VANILLA) FRUIT OIL | 0 | 100% | 2 products | none identified |
| ACETYL TETRAPEPTIDE-5 | 0 | 100% | 1 products | none identified |
| SODIUM ASCORBYL PHOSPHATE | 0 | 99% | 2 products | none identified |
| SORBITAN ISOSTEARATE | 0 | 99% | 2 products | none identified |
| ALGAE EXTRACT | 0 | 94% | 1 products | none identified |
| ALLANTOIN | 0 | 94% | 1 products | none identified |
| CAPRYLYL GLYCOL | 0 | 94% | 4 products | none identified |
| ETHYLHEXYL HYDROXYSTEARATE | 0 | 94% | 2 products | none identified |
| GLYCINE SOJA PROTEIN | 0 | 94% | 1 products | none identified |
| HYALURONIC ACID | 0 | 94% | 3 products | none identified |
| HYDROLYZED ELASTIN | 0 | 94% | 9 products | none identified |
| MENTHYL LACTATE | 0 | 94% | 1 products | none identified |
| POTASSIUM ACESULFAME | 0 | 94% | 2 products | none identified |
| PPG-12/ SMDI COPOLYMER | 0 | 94% | 3 products | none identified |
| VITIS VINIFERA (GRAPE) SEED OIL | 0 | 94% | 3 products | none identified |
| XANTHAN GUM | 0 | 94% | 7 products | none identified |
| CITRUS AURANTIUM BERGAMIA (BERGAMOT) FRUIT EXTRACT | 0 | 94% | 1 products | none identified |
| CARBOMER | 0 | 93% | 18 products | none identified |
| PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL | 0 | 93% | 4 products | none identified |
| SODIUM CHLORIDE | 0 | 0% | 2 products | innocuous |
| WATER | 0 | 0% | 29 products | innocuous |
* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of carcinogenicity | products that may be aerosolized (airborne) | NANO TITANIUM DIOXIDE |
| Limited evidence of carcinogenicity | TRISODIUM NTA | |
| Cancer - not classifiable/not likely to be human carcinogen | products that may be aerosolized (airborne) | SILICA |
| Cancer - not classifiable/not likely to be human carcinogen | BHT, CHOLESTEROL, ISOPROPYL ALCOHOL, TRIETHANOLAMINE | |
| Not likely to be carcinogenic in humans | CARRAGEENAN, STEARIC ACID | |
| Cancer - limited evidence | COCAMIDE DEA, RETINYL PALMITATE, SD ALCOHOL 40C | |
| Cancer - not classifiable/not likely to be human carcinogen | ETHYLENEDIAMINE, LACTIC ACID, SALICYLIC ACID | |
| One or more in vitro tests on mammalian cells show positive mutation results | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) | |
| One or more in vitro tests on mammalian cells show positive mutation results | ASCORBIC ACID (VITAMIN C), BUTYLPARABEN, DIAZOLIDINYL UREA, DISODIUM EDTA, ETHYLPARABEN, GLUCOSE, GLYCERIN, METHYLPARABEN, N6-FURFURYLADENINE, NORDIHYDROGUAIARETIC ACID, POLYSORBATE-80, POTASSIUM SORBATE, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM BENZOATE, SODIUM CHLORIDE, SODIUM HYDROXIDE, SODIUM LAURYL SULFATE, SORBITOL, TOCOPHEROL, TOCOPHERYL ACETATE, ZEATIN | |
| One or more animal studies show tumor formation at moderate doses | ALUMINA, PEG-100 STEARATE, | |
| One or more animal studies show tumor formation at moderate doses | CYCLOPENTASILOXANE | |
| One or more in vitro tests non-mammalian cells show positive mutation results | CITRUS AURANTIFOLIA (LIME) OIL, ETHOXYDIGLYCOL, LAURETH-23, OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL | |
| One or more animal studies show tumor formation at high doses | CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, STEARYL ALCOHOL, ZEA MAYS (CORN) OIL | |
| One or more in vitro tests on microorganisms show positive mutation results | GLUCOSAMINE HCL |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of reproductive toxicity | SD ALCOHOL 40C | |
| Human nervous system toxicant - moderate evidence | ALUMINA, MAGNESIUM ALUMINUM SILICATE | |
| One or more animal studies show any effects at very low doses | BUTYLPARABEN | |
| One or more animal studies show reproductive effects at very low doses | POLYSORBATE-80 | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| One or more animal studies show reproductive effects at low doses | RETINYL PALMITATE | |
| Limited evidence of developmental toxicity | ISOPROPYL ALCOHOL, OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show reproductive effects at moderate doses | CHOLECALCIFEROL, CHOLESTEROL, GLYCERIN, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM HYALURONATE, | |
| One or more animal studies show reproductive effects at moderate doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at high doses | BHT, BUTYLENE GLYCOL, DISODIUM EDTA, ETHOXYDIGLYCOL, ETHYLENEDIAMINE, ETHYLPARABEN, GLYCOLIC ACID, HYDROXYETHYLCELLULOSE, SODIUM BENZOATE, SODIUM LAURYL SULFATE, TRISODIUM NTA, ZEA MAYS (CORN) OIL, PAPAIN, PEG-100 STEARATE, PYRUS COMMUNIS (PEAR) FRUIT EXTRACT |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN, ETHYLENEDIAMINE | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits | GLYCOLIC ACID, LACTIC ACID | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR) | products that may be aerosolized (airborne) | IODOPROPYNYL BUTYLCARBAMATE |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin | products for use on damaged skin | PEG-12 GLYCERYL DISTEARATE, PEG-20 METHYL GLUCOSE, PEG-20 METHYL GLUCOSE SESQUISTEARATE, PEG-5 SOYA STEROL, PEG-60 ALMOND GLYCERIDES, PEG-100 STEARATE |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), HOMOSALATE, OCTOCRYLENE, PHENOXYETHANOL, IODOPROPYNYL BUTYLCARBAMATE, OCTISALATE, OXYBENZONE (BENZOPHENONE-3) | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | products for use around the eyes; products for use on the lips | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | CHOLECALCIFEROL, CITRIC ACID, GLYCOLIC ACID, LACTIC ACID, MALIC ACID, RETINYL PALMITATE, SALICYLIC ACID | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CITRUS AURANTIFOLIA (LIME) OIL, DIMETHICONE, GLYCERYL CAPRATE, PEG-5 SOYA STEROL, MALIC ACID | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | ALOE BARBADENSIS (ALOE VERA) GEL, COCAMIDE DEA, COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, GLYCOLIC ACID, IODOPROPYNYL BUTYLCARBAMATE, LACTIC ACID, LECITHIN, MALIC ACID, PEG-12 GLYCERYL DISTEARATE, PEG-20 METHYL GLUCOSE, PEG-20 METHYL GLUCOSE SESQUISTEARATE, PEG-5 SOYA STEROL, PEG-60 ALMOND GLYCERIDES, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM BENZOATE, SODIUM HEXAMETAPHOSPHATE, SODIUM LAURYL SULFATE, STYRENE/ ACRYLATES COPOLYMER, TRIETHANOLAMINE, PEG-100 STEARATE |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Strong evidence of human neurotoxicity | ISOPROPYL ALCOHOL, ALUMINA, MAGNESIUM ALUMINUM SILICATE | |
| One or more animal studies show brain and nervous system effects at very low doses | SODIUM HYDROXIDE, STEARIC ACID | |
| One or more animal studies show brain and nervous system effects at low doses | BHT, DISODIUM EDTA, LAURETH-23, SALICYLIC ACID, ZEA MAYS (CORN) OIL | |
| One or more animal studies show any effects at moderate doses | CYCLOPENTASILOXANE | |
| One or more animal studies show brain and nervous system effects at moderate doses | CARRAGEENAN, CHOLECALCIFEROL, GLUCOSE, GLYCOLIC ACID, LECITHIN, METHYLPARABEN, PHENOXYETHANOL, SODIUM BENZOATE, SODIUM HYALURONATE, SODIUM LAURYL SULFATE, TROMETHAMINE | |
| One or more animal studies show brain and nervous system effects at high doses | BUTYLENE GLYCOL, CHOLESTEROL, DIAZOLIDINYL UREA, ETHOXYDIGLYCOL, GLUCOSAMINE HCL, GLYCERIN, HYDROXYETHYLCELLULOSE, LACTIC ACID, OXYBENZONE (BENZOPHENONE-3), POLYSORBATE-80, POTASSIUM SORBATE, PROPYLENE GLYCOL, RETINYL PALMITATE, SODIUM HEXAMETAPHOSPHATE | |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | SD ALCOHOL 40C |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN | |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show endocrine disruption at moderate doses | CYCLOPENTASILOXANE | |
| One or more animal studies show endocrine disruption at moderate doses | ISOBUTYLPARABEN | |
| One or more studies show weak endocrine disruption | HOMOSALATE | |
| One or more animal studies show endocrine system disruption at high doses | BHT, BUTYLENE GLYCOL, CHOLESTEROL, DIAZOLIDINYL UREA, DISODIUM EDTA, GLYCERIN, OLEANOLIC ACID, SODIUM LAURYL SULFATE, TRIETHANOLAMINE |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | BHT, COCAMIDE DEA, COCAMIDOPROPYL BETAINE, DIAZOLIDINYL UREA, IMIDAZOLIDINYL UREA, SODIUM, TRIETHANOLAMINE, PAPAIN | |
| Possible human photoallergenic toxicant | OXYBENZONE (BENZOPHENONE-3) | |
| Human any toxicant - strong evidence | IODOPROPYNYL BUTYLCARBAMATE | |
| Human immune and respiratory toxicant - strong evidence | AND products that may be aerosolized (airborne) | ETHYLENEDIAMINE, LECITHIN |
| Human immune system toxicant - strong evidence | products that may be aerosolized (airborne) | SILICA |
| Human skin toxicant - strong evidence | BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| One or more animal studies show immune effects at low doses | products that may be aerosolized (airborne) | NANO TITANIUM DIOXIDE |
| One or more human case studies show possible immune effects | OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| Associated with immunotoxicity | AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE) |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human any toxicant | METHYLPARABEN | |
| Known human respiratory toxicant | products that may be aerosolized (airborne) | SILICA |
| Limited evidence of eye toxicity | products for use around the eyes | ETHYLHEXYLGLYCERIN, TETRASODIUM EDTA |
| Limited evidence of respiratory toxicity | products that may be aerosolized (airborne) | PROPYLENE GLYCOL |
| Possible human immune system toxicant | TRIETHANOLAMINE, PAPAIN | |
| One or more animal studies show blood effects at very low doses | CARRAGEENAN, GLYCERIN, SODIUM HYDROXIDE, | |
| One or more animal studies show respiratory effects at very low doses | products that may be aerosolized (airborne) | STEARIC ACID, NANO TITANIUM DIOXIDE |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CITRIC ACID, COCAMIDE DEA, ETHYLENEDIAMINE, GLYCOLIC ACID, ISOPROPYL ALCOHOL, LACTIC ACID, LAURETH-23, MALIC ACID, PHENOXYETHANOL, SALICYLIC ACID, SODIUM LAURETH SULFATE |
| One or more animal studies show blood effects at low doses | N6-FURFURYLADENINE, CHOLECALCIFEROL, DISODIUM EDTA, ISOPROPYL PALMITATE, SODIUM BENZOATE, SODIUM HEXAMETAPHOSPHATE, SODIUM LAURYL SULFATE, | |
| One or more animal studies show respiratory effects at low doses | products that may be aerosolized (airborne) | BHT |
| One or more animal studies show sense organ effects at low doses | products for use around the eyes, mouth, or lips | ETHOXYDIGLYCOL, SODIUM CHLORIDE |
| Limited evidence of any toxicity | products that may be aerosolized (airborne) | ALUMINA |
| Limited evidence of any toxicity | MAGNESIUM ALUMINUM SILICATE, IODOPROPYNYL BUTYLCARBAMATE, SD ALCOHOL 40C, BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, PEG-12 GLYCERYL DISTEARATE, PEG-20 METHYL GLUCOSE, PEG-20 METHYL GLUCOSE SESQUISTEARATE, PEG-5 SOYA STEROL, PEG-60 ALMOND GLYCERIDES, PROPYLPARABEN, PEG-100 STEARATE, RETINYL PALMITATE | |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | ALOE BARBADENSIS (ALOE VERA) GEL, GLUCOSAMINE HCL, GLYCERYL MONOSTEARATE, GLYCOL STEARATE, OCTISALATE, OLEANOLIC ACID, POTASSIUM SORBATE, TOCOPHERYL ACETATE, TROMETHAMINE, PYRUS COMMUNIS (PEAR) FRUIT EXTRACT, | |
| One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient) | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient) | TRISODIUM NTA, TRISODIUM EDTA, ZEA MAYS (CORN) OIL, | |
| One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | BUTYLENE GLYCOL, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CETYL ALCOHOL, CYCLOPENTASILOXANE, HYDROLYZED COLLAGEN, POLYSORBATE-80, SODIUM HYALURONATE, STEARYL ALCOHOL |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | DIAZOLIDINYL UREA, ISOPROPYL MYRISTATE, PANTHENOL, SODIUM, TRIBEHENIN, CITRUS AURANTIUM DULCIS (ORANGE) FLOWER OIL, HYDROXYETHYLCELLULOSE, IMIDAZOLIDINYL UREA, SORBITOL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, OCTOCRYLENE, | |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | GLUCOSE |
| One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient) | products for use around the eyes, mouth, or lips | CHOLESTEROL |
| Classified as expected to be toxic or harmful | DIMETHICONE, HOMOSALATE | |
| Classified as not expected to be potentially toxic or harmful | ALGAE EXTRACT, ALLANTOIN, ASCORBIC ACID (VITAMIN C), AVOBENZONE (PARSOL 1789 | BUTYL METHOXYDIBENZOYLMETHANE), C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CAPRYLYL GLYCOL, CARBOMER, CITRUS AURANTIFOLIA (LIME) OIL, COCAMIDOPROPYL BETAINE, ETHYLHEXYL HYDROXYSTEARATE, ETHYLHEXYL PALMITATE, GLYCINE SOJA PROTEIN, HEXYLDECANOL, HYALURONIC ACID, HYDROLYZED ELASTIN, LECITHIN, MENTHYL LACTATE, METHYL GLUCOSE SESQUISTEARATE, CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT, POTASSIUM ACESULFAME, PPG-12/ SMDI COPOLYMER, SORBITAN STEARATE, SQUALANE, TOCOPHEROL, VITIS VINIFERA (GRAPE) SEED OIL, WATER, XANTHAN GUM, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, CITRUS AURANTIUM BERGAMIA (BERGAMOT) FRUIT EXTRACT, HYDROLYZED RICE BRAN PROTEIN |
Multiple, additive exposure sources*
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to very low doses | CHOLECALCIFEROL, ETHYLENEDIAMINE | |
| Allowed workplace exposures restricted to low doses | NANO TITANIUM DIOXIDE, PHENOXYETHANOL, TETRASODIUM EDTA | |
| Allowed workplace exposures restricted to low doses | BHT | |
| Allowed workplace exposures restricted to moderate doses | ALUMINA, GLYCERIN, TRIETHANOLAMINE, | |
| Allowed workplace exposures restricted to moderate doses | products that may be aerosolized (airborne) | ISOPROPYL ALCOHOL |
| No workplace limits set | GLYCOLIC ACID, LACTIC ACID, SODIUM HYDROXIDE |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CARRAGEENAN, SILICA, NANO TITANIUM DIOXIDE | |
| One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood | BHT | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | LAURETH-23, SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CHOLESTEROL, CITRIC ACID, CYCLOPENTASILOXANE, GLUCOSE, GLYCERIN, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, SODIUM, SODIUM BENZOATE, ZEA MAYS (CORN) OIL, PROPYLENE GLYCOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE), OCTOCRYLENE | |
| Interferes with gene expresion | BUTYLPARABEN, METHYLPARABEN | |
| Does not produces excess reactive oxygen species or other harmful biochemical changes. | OCTISALATE |
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