Lanacane || Skin Deep: Cosmetic Safety Reviews

BRAND: Lanacane

Manufacturer: Combe Inc.

BRAND SUMMARY

product score range	6	to	7
product count	8 (browse)
ingredient count	35
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 8 products by Lanacane

Product type(s) by this brand in Skin Deep: after sun product (1), anti-itch/rash cream (4), pain relief (1)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	4 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
FRAGRANCE	8	100%	4 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
PEG-100 STEARATE	7	69%	2 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
BENZOCAINE	7	61%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SODIUM BORATE	6	51%	2 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Occupational hazards
TRIETHANOLAMINE	6	58%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ZINC OXIDE (NON-NANO)	2	82%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
PROPYLPARABEN	5	71%	4 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	3 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
ZINC PYRITHIONE	5	66%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TOCOPHERYL ACETATE	4	81%	3 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
MINERAL OIL	2	73%	2 products	Organ system toxicity (non-reproductive), Occupational hazards
ISOPROPYL ALCOHOL	4	72%	2 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BENZETHONIUM CHLORIDE	4	70%	4 products	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive)
CHOLECALCIFEROL	4	61%	3 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Occupational hazards
DIMETHICONE	2	74%	2 products	Violations, restrictions & warnings
ACETYLATED LANOLIN ALCOHOL	2	87%	2 products	Allergies/immunotoxicity
ETHOXYDIGLYCOL	2	82%	2 products	Organ system toxicity (non-reproductive)
DIOCTYL SODIUM SULFOSUCCINATE	2	81%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ZEA MAYS (CORN) OIL	2	79%	3 products	Neurotoxicity
GLYCERIN	2	74%	4 products	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CETYL ACETATE	1	93%	2 products	none identified
SORBITAN STEARATE	1	92%	2 products	none identified
GLYCERYL MONOSTEARATE	1	88%	2 products	none identified
CETYL ALCOHOL	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL MYRISTATE	1	86%	2 products	Irritation (skin, eyes, or lungs)
4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL	1	73%	2 products	none identified
ALOE BARBADENSIS (ALOE VERA)	1	72%	1 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	2 products	none identified
STEARAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE	0	100%	2 products	none identified
VP/ EICOSENE COPOLYMER	0	94%	1 products	none identified
SULFATED CASTOR OIL	0	94%	2 products	none identified
GLYCERYL STEARATE SE	0	93%	2 products	none identified
WATER	0	0%	4 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - not classifiable/not likely to be human carcinogen		ISOPROPYL ALCOHOL, TRIETHANOLAMINE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		RETINYL PALMITATE
One or more in vitro tests on mammalian cells show positive mutation results		BENZETHONIUM CHLORIDE, GLYCERIN, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE, ZINC OXIDE (NON-NANO)
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE
One or more in vitro tests non-mammalian cells show positive mutation results		ALOE BARBADENSIS (ALOE VERA), ETHOXYDIGLYCOL, SODIUM BORATE
One or more animal studies show tumor formation at high doses		ZEA MAYS (CORN) OIL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		SODIUM BORATE
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		CHOLECALCIFEROL, GLYCERIN, ZINC PYRITHIONE,
One or more animal studies show reproductive effects at moderate doses		ALOE BARBADENSIS (ALOE VERA)
One or more animal studies show developmental effects at high doses		ZINC OXIDE (NON-NANO)
One or more animal studies show reproductive effects at high doses		DIOCTYL SODIUM SULFOSUCCINATE, ETHOXYDIGLYCOL, ZEA MAYS (CORN) OIL, PEG-100 STEARATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN, BENZOCAINE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on infant skin	products for use on infant skin	SODIUM BORATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		ZINC PYRITHIONE, BENZETHONIUM CHLORIDE, CHOLECALCIFEROL, RETINYL PALMITATE, SODIUM BORATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ALOE BARBADENSIS (ALOE VERA), ALOE BARBADENSIS (ALOE VERA) GEL, BENZETHONIUM CHLORIDE, SODIUM BORATE, TRIETHANOLAMINE, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		BENZETHONIUM CHLORIDE, STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		ZEA MAYS (CORN) OIL
One or more animal studies show brain and nervous system effects at moderate doses		CHOLECALCIFEROL, DIOCTYL SODIUM SULFOSUCCINATE, METHYLPARABEN, ZINC PYRITHIONE
One or more animal studies show brain and nervous system effects at high doses		4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, BENZOCAINE, ETHOXYDIGLYCOL, GLYCERIN, RETINYL PALMITATE, SODIUM BORATE, ZINC OXIDE (NON-NANO)

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		METHYLPARABEN, PROPYLPARABEN
One or more animal studies show endocrine disruption at moderate doses		BENZETHONIUM CHLORIDE
One or more animal studies show endocrine system disruption at high doses		GLYCERIN, SODIUM BORATE, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZOCAINE, FRAGRANCE, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Human immune and respiratory toxicant - strong evidence		ZINC OXIDE (NON-NANO)
Human skin toxicant - strong evidence		ACETYLATED LANOLIN ALCOHOL, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of immune system toxicity		ZINC PYRITHIONE

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		ZINC OXIDE (NON-NANO), ZINC PYRITHIONE
Not suspected to be persistent		4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ACETYLATED LANOLIN ALCOHOL, BENZOCAINE, CETYL ACETATE, CHOLECALCIFEROL, DIMETHICONE, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, ISOPROPYL MYRISTATE, METHYLPARABEN, PROPYLPARABEN, RETINYL PALMITATE, SORBITAN STEARATE, STEARIC ACID, SULFATED CASTOR OIL, PEG-100 STEARATE
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		BENZETHONIUM CHLORIDE, VP/ EICOSENE COPOLYMER, TOCOPHERYL ACETATE, WATER, ZEA MAYS (CORN) OIL
Not suspected to be bioaccumulative		ISOPROPYL ALCOHOL, SODIUM BORATE, TRIETHANOLAMINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Possible human immune system toxicant		TRIETHANOLAMINE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	BENZETHONIUM CHLORIDE, STEARIC ACID
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	DIOCTYL SODIUM SULFOSUCCINATE, ISOPROPYL ALCOHOL
One or more animal studies show blood effects at low doses		BENZOCAINE, CHOLECALCIFEROL, SODIUM BORATE, ZINC PYRITHIONE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	ETHOXYDIGLYCOL, MINERAL OIL
Limited evidence of any toxicity	products that may be aerosolized (airborne)	ZINC OXIDE (NON-NANO)
Limited evidence of sense organ toxicity		PROPYLPARABEN, PEG-100 STEARATE, RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALOE BARBADENSIS (ALOE VERA) GEL, GLYCERYL MONOSTEARATE, TOCOPHERYL ACETATE, ZEA MAYS (CORN) OIL,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CETYL ALCOHOL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ISOPROPYL MYRISTATE
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as not expected to be potentially toxic or harmful		4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ACETYLATED LANOLIN ALCOHOL, ALOE BARBADENSIS (ALOE VERA), CETYL ACETATE, GLYCERYL STEARATE SE, VP/ EICOSENE COPOLYMER, SORBITAN STEARATE, SULFATED CASTOR OIL, WATER

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Prohibited for use in food		SODIUM BORATE
Occupational hazards related to handling		ISOPROPYL ALCOHOL
Occupational hazards related to handling	products for use around the mouth; products for use on the lips; products for use on skin	CHOLECALCIFEROL

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		SODIUM BORATE
Designated as safe for general or specific, limited use in food		ALOE BARBADENSIS (ALOE VERA), ALOE BARBADENSIS (ALOE VERA) GEL, CETYL ALCOHOL, CHOLECALCIFEROL, DIMETHICONE, DIOCTYL SODIUM SULFOSUCCINATE, ETHOXYDIGLYCOL, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, ISOPROPYL ALCOHOL, ISOPROPYL MYRISTATE, METHYLPARABEN, MINERAL OIL, PROPYLPARABEN, RETINYL PALMITATE, SORBITAN STEARATE, STEARIC ACID, TOCOPHERYL ACETATE, TRIETHANOLAMINE, ZINC OXIDE (NON-NANO), PEG-100 STEARATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		ISOPROPYL ALCOHOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	ISOPROPYL MYRISTATE
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show skin irritation at low doses		DIOCTYL SODIUM SULFOSUCCINATE, METHYLPARABEN, STEARIC ACID
One or more animal studies show skin irritation at moderate doses		BENZETHONIUM CHLORIDE, BENZOCAINE, CETYL ACETATE, ETHOXYDIGLYCOL, GLYCERIN, MINERAL OIL, SORBITAN STEARATE, ZEA MAYS (CORN) OIL, ZINC OXIDE (NON-NANO)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		CHOLECALCIFEROL
Allowed workplace exposures restricted to low doses		SODIUM BORATE, ZINC OXIDE (NON-NANO)
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MINERAL OIL, TRIETHANOLAMINE,
Allowed workplace exposures restricted to moderate doses	products that may be aerosolized (airborne)	ISOPROPYL ALCOHOL

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		DIOCTYL SODIUM SULFOSUCCINATE, GLYCERIN, ZEA MAYS (CORN) OIL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE
Interferes with gene expresion		METHYLPARABEN