Lubriderm || Skin Deep: Cosmetic Safety Reviews

BRAND: Lubriderm

Manufacturer: Pfizer

BRAND SUMMARY

product score range	5	to	8
product count	32 (browse)
ingredient count	93
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 32 products by Lubriderm

Product type(s) by this brand in Skin Deep: hand cream (3), moisturizer (18), sunscreen: moisturizer (2)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	11 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
ALUMINUM STARCH OCTENYLSUCCINATE	9	74%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ARSENIC, LEAD, HEAVY METALS)
DMDM HYDANTOIN	7	71%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
OXYBENZONE (BENZOPHENONE-3)	9	55%	2 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	13 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
CETEARETH-6	5	71%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	6	65%	2 products	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
METHYLDIBROMO GLUTARONITRILE	8	60%	5 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PEG-40 STEARATE	4	70%	5 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-100 STEARATE	4	69%	6 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
BENZALKONIUM CHLORIDE	7	62%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
BUTYLPARABEN	6	79%	6 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
GLYCERYL STEARATE/ PEG-100 STEARATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
LECITHIN	3	70%	5 products	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
IODOPROPYNYL BUTYLCARBAMATE	4	65%	10 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BENZYL ALCOHOL	6	64%	1 products	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BHT	6	61%	4 products	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
DIAZOLIDINYL UREA	6	59%	10 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	9 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHYLPARABEN	5	80%	7 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLPARABEN	5	71%	9 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	68%	5 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
UNSPECIFIED WAXES	4	100%	2 products	Miscellaneous
TITANIUM DIOXIDE (NON-NANO)	1	81%	6 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	6 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
MINERAL OIL	2	73%	14 products	Organ system toxicity (non-reproductive), Occupational hazards
LANOLIN	4	71%	5 products	Allergies/immunotoxicity
OCTISALATE	3	68%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	11 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LANOLIN ALCOHOL	2	87%	5 products	Allergies/immunotoxicity
BENZALDEHYDE	3	79%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
DISODIUM EDTA	3	78%	15 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	3	78%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	6 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIMETHICONE	2	74%	9 products	Violations, restrictions & warnings
CITRIC ACID	3	72%	3 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
HYDROGENATED POLYDECENE	2	94%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
PETROLATUM	2	94%	14 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
WHITE PETROLATUM	2	94%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
PANTHENOL	2	88%	1 products	Multiple, additive exposure sources
TOCOPHEROL	2	87%	1 products	Contamination concerns (HYDROQUINONE)
DISTEARYLDIMONIUM CHLORIDE	2	84%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CYCLOMETHICONE	2	83%	4 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	2	81%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
CASTOR OIL	2	80%	2 products	Developmental/reproductive toxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
POLYSORBATE-80	2	80%	4 products	Developmental/reproductive toxicity
SYNTHETIC WAX	2	79%	1 products	Irritation (skin, eyes, or lungs), Occupational hazards
GLYCERIN	2	74%	12 products	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	5 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SODIUM BENZOATE	2	69%	4 products	Organ system toxicity (non-reproductive)
C12-15 ALKYL BENZOATE	0	94%	6 products	none identified
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	2 products	none identified
HYDROLYZED MILK PROTEIN	1	94%	1 products	Multiple, additive exposure sources
CETEARYL ALCOHOL	0	93%	2 products	none identified
MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA)	1	93%	2 products	Organ system toxicity (non-reproductive)
SORBITAN STEARATE	1	92%	2 products	none identified
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE	0	90%	5 products	Enhanced skin absorption
GLYCERYL MONOSTEARATE	1	88%	13 products	none identified
GLYCINE SOJA (SOYBEAN) OIL	1	88%	2 products	none identified
ISOPROPYL ISOSTEARATE	1	88%	4 products	none identified
SORBITOL	1	88%	5 products	none identified
STEARETH-20	1	88%	1 products	none identified
CETYL ALCOHOL	1	87%	19 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL PALMITATE	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
STEARYL ALCOHOL	1	84%	1 products	Irritation (skin, eyes, or lungs)
BUTYLENE GLYCOL	1	79%	1 products	Irritation (skin, eyes, or lungs)
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	2 products	none identified
AVENA SATIVA (OAT) KERNEL EXTRACT	0	100%	3 products	none identified
AVENA SATIVA (OAT) KERNEL OIL	0	100%	1 products	none identified
BRASSICA ALBA (WHITE MUSTARD) SEED EXTRACT	0	100%	2 products	none identified
CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) SEED OIL	0	100%	2 products	none identified
CASSIA ANGUSTIFOLIA (ALEXANDRIAN SENNA) SEED POLYSACCHARIDE	0	100%	2 products	none identified
EMULSIFYING WAX	0	100%	5 products	none identified
ETHYLHEXYL ISONANOATE	0	100%	1 products	none identified
ETHYLHEXYL ISONONANOATE	0	100%	1 products	none identified
GLYCINE SOJA (SOYBEAN) STEROLS	0	100%	4 products	none identified
SODIUM BEHENOYL LACTYLATE	0	100%	2 products	none identified
TRI(PPG-3 MYRISTYL ETHER) CITRATE	0	100%	12 products	none identified
C11-13 ISOPARAFFIN	0	100%	1 products	none identified
TRIMETHYLPENTANEDIOL/ADIPIC ACID/GLYCERIN CROSSPOLYMER	0	100%	2 products	none identified
SORBITOL LAURATE	0	100%	2 products	none identified
AVENA SATIVA (OAT) KERNEL FLOUR	0	94%	3 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER)	0	94%	4 products	none identified
HYDROLYZED GLYCINE SOJA (SOY) PROTEIN	0	94%	1 products	none identified
SODIUM CITRATE	0	94%	1 products	none identified
SODIUM PYRUVATE	0	94%	4 products	none identified
THEOBROMA CACAO (CACAO) SEED BUTTER	0	94%	2 products	none identified
XANTHAN GUM	0	94%	16 products	none identified
CARBOMER	0	93%	8 products	none identified
GLYCERYL STEARATE SE	0	93%	2 products	none identified
SODIUM CHLORIDE	0	0%	2 products	innocuous
WATER	0	0%	19 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Cancer - not classifiable/not likely to be human carcinogen		BHT, TRIETHANOLAMINE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		RETINYL PALMITATE
One or more in vitro tests on mammalian cells show positive mutation results		BENZALKONIUM CHLORIDE, BENZYL ALCOHOL, BUTYLPARABEN, DIAZOLIDINYL UREA, DISODIUM EDTA, EDTA, ETHYLPARABEN, GLYCERIN, METHYLPARABEN, POLYSORBATE-80, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM BENZOATE, SODIUM CHLORIDE, SODIUM HYDROXIDE, SORBITOL, TOCOPHEROL, TOCOPHERYL ACETATE, BENZALDEHYDE
One or more animal studies show tumor formation at moderate doses		PEG-40 STEARATE, SYNTHETIC WAX, PEG-100 STEARATE
One or more in vitro tests non-mammalian cells show positive mutation results		GLYCINE SOJA (SOYBEAN) OIL, OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show tumor formation at high doses		STEARYL ALCOHOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		CASTOR OIL
Human nervous system toxicant - moderate evidence		ALUMINUM STARCH OCTENYLSUCCINATE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show reproductive effects at very low doses		POLYSORBATE-80
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, PROPYLENE GLYCOL,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at high doses		BENZYL ALCOHOL, BHT, BUTYLENE GLYCOL, DISODIUM EDTA, EDTA, ETHYLPARABEN, METHYLDIBROMO GLUTARONITRILE, PEG-40 STEARATE, SODIUM BENZOATE, PEG-100 STEARATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLDIBROMO GLUTARONITRILE, METHYLPARABEN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	products that may be aerosolized (airborne)	DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-20, CETEARETH-6, GLYCERYL STEARATE/ PEG-100 STEARATE, PEG-40 STEARATE, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE, OCTISALATE, OXYBENZONE (BENZOPHENONE-3)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		BENZALKONIUM CHLORIDE, CITRIC ACID, RETINYL PALMITATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		BENZYL ALCOHOL, DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ALUMINUM STARCH OCTENYLSUCCINATE, BENZALKONIUM CHLORIDE, BENZYL ALCOHOL, CETEARETH-20, CETEARETH-6, DIAZOLIDINYL UREA, GLYCERYL STEARATE/ PEG-100 STEARATE, IODOPROPYNYL BUTYLCARBAMATE, LECITHIN, METHYLDIBROMO GLUTARONITRILE, PEG-40 STEARATE, PROPYLENE GLYCOL, SODIUM BENZOATE, TRIETHANOLAMINE, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		BENZYL ALCOHOL, ALUMINUM STARCH OCTENYLSUCCINATE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE, STEARIC ACID, BENZALDEHYDE
One or more animal studies show brain and nervous system effects at low doses		BHT, DISODIUM EDTA
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-20, CETEARETH-6, EDTA, LECITHIN, METHYLPARABEN, SODIUM BENZOATE
One or more animal studies show brain and nervous system effects at high doses		BUTYLENE GLYCOL, DIAZOLIDINYL UREA, DISTEARYLDIMONIUM CHLORIDE, GLYCERIN, OXYBENZONE (BENZOPHENONE-3), POLYSORBATE-80, PROPYLENE GLYCOL, RETINYL PALMITATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show endocrine system disruption at high doses		BHT, BUTYLENE GLYCOL, DIAZOLIDINYL UREA, DISODIUM EDTA, GLYCERIN, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZALKONIUM CHLORIDE, BHT, DIAZOLIDINYL UREA, DMDM HYDANTOIN, FRAGRANCE, LANOLIN, METHYLDIBROMO GLUTARONITRILE, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Human any toxicant - strong evidence		IODOPROPYNYL BUTYLCARBAMATE
Human immune and respiratory toxicant - strong evidence	AND products that may be aerosolized (airborne)	LECITHIN
Human skin toxicant - strong evidence		BUTYLPARABEN, ETHYLPARABEN, LANOLIN ALCOHOL, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more human case studies show possible allergenic effects		BENZYL ALCOHOL, OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		BENZALKONIUM CHLORIDE, BUTYLENE GLYCOL, BUTYLPARABEN, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CASTOR OIL, CETEARETH-20, CETEARETH-6, CETEARYL ALCOHOL, CITRIC ACID, DIAZOLIDINYL UREA, DIMETHICONE, DISODIUM EDTA, DISTEARYLDIMONIUM CHLORIDE, DMDM HYDANTOIN, ETHYLPARABEN, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, GLYCINE SOJA (SOYBEAN) OIL, IODOPROPYNYL BUTYLCARBAMATE, ISOPROPYL ISOSTEARATE, ISOPROPYL PALMITATE, LANOLIN, LECITHIN, METHYLDIBROMO GLUTARONITRILE, METHYLPARABEN, OCTISALATE, PANTHENOL, PEG-40 STEARATE, PROPYLPARABEN, RETINYL PALMITATE, SODIUM BENZOATE, SODIUM CITRATE, SODIUM PYRUVATE, SORBITAN STEARATE, SORBITOL, STEARIC ACID, STEARYL ALCOHOL, SYNTHETIC WAX, PEG-100 STEARATE, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE, STEARETH-20
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		CARBOMER, SODIUM CHLORIDE, TOCOPHEROL, TOCOPHERYL ACETATE, WATER
Not suspected to be bioaccumulative		EDTA, HYDROGENATED POLYDECENE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), PETROLATUM, SODIUM HYDROXIDE, TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, WHITE PETROLATUM

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Limited evidence of eye toxicity	products for use around the eyes	DISTEARYLDIMONIUM CHLORIDE, TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		BENZALKONIUM CHLORIDE, TRIETHANOLAMINE
One or more animal studies show kidney or renal system effects at very low doses		GLYCERIN, SODIUM HYDROXIDE,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	STEARIC ACID, TITANIUM DIOXIDE (NON-NANO), BENZALDEHYDE
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	CITRIC ACID, METHYLDIBROMO GLUTARONITRILE
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, EDTA, ISOPROPYL PALMITATE, SODIUM BENZOATE,
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CETEARETH-20, CETEARETH-6, MINERAL OIL, SODIUM CHLORIDE
Classified as toxic or harmful	products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne)	BENZYL ALCOHOL
Limited evidence of any toxicity		ALUMINUM STARCH OCTENYLSUCCINATE, IODOPROPYNYL BUTYLCARBAMATE, BUTYLPARABEN, ETHYLPARABEN, GLYCERYL STEARATE/ PEG-100 STEARATE, PEG-40 STEARATE, PROPYLPARABEN, PEG-100 STEARATE, RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		DMDM HYDANTOIN, GLYCERYL MONOSTEARATE, OCTISALATE, TOCOPHERYL ACETATE, STEARETH-20,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL, CASTOR OIL, CETYL ALCOHOL, CYCLOMETHICONE, ISOPROPYL ISOSTEARATE, POLYSORBATE-80, STEARYL ALCOHOL, SYNTHETIC WAX
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		DIAZOLIDINYL UREA, GLYCINE SOJA (SOYBEAN) OIL, PANTHENOL, SORBITOL,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as expected to be toxic or harmful		HYDROGENATED POLYDECENE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), PETROLATUM, WHITE PETROLATUM
Classified as not expected to be potentially toxic or harmful		AVENA SATIVA (OAT) KERNEL FLOUR, BUTYROSPERMUM PARKII (SHEA BUTTER), C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CARBOMER, CETEARYL ALCOHOL, GLYCERYL STEARATE SE, HYDROLYZED MILK PROTEIN, HYDROLYZED GLYCINE SOJA (SOY) PROTEIN, LANOLIN, LANOLIN ALCOHOL, LECITHIN, SODIUM CITRATE, SODIUM PYRUVATE, SORBITAN STEARATE, THEOBROMA CACAO (CACAO) SEED BUTTER, TOCOPHEROL, WATER, XANTHAN GUM, PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE, UNSPECIFIED WAXES
Occupational hazards related to handling		SODIUM HYDROXIDE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		HYDROLYZED MILK PROTEIN, LECITHIN, PANTHENOL
Designated as safe for general or specific, limited use in food		ALUMINUM STARCH OCTENYLSUCCINATE, BENZYL ALCOHOL, BHT, BUTYLENE GLYCOL, BUTYLPARABEN, CASTOR OIL, CETYL ALCOHOL, CITRIC ACID, DIMETHICONE, DISODIUM EDTA, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, GLYCERYL STEARATE/ PEG-100 STEARATE, ISOPROPYL PALMITATE, LANOLIN, LECITHIN, METHYLPARABEN, MINERAL OIL, PEG-40 STEARATE, PETROLATUM, POLYSORBATE-80, PROPYLENE GLYCOL, PROPYLPARABEN, RETINYL PALMITATE, SODIUM BENZOATE, SODIUM CHLORIDE, SODIUM CITRATE, SODIUM HYDROXIDE, SORBITAN STEARATE, SORBITOL, STEARIC ACID, STEARYL ALCOHOL, SYNTHETIC WAX, TETRASODIUM EDTA, THEOBROMA CACAO (CACAO) SEED BUTTER, TITANIUM DIOXIDE (NON-NANO), TOCOPHEROL, TOCOPHERYL ACETATE, TRIETHANOLAMINE, WHITE PETROLATUM, XANTHAN GUM, BENZALDEHYDE, PEG-100 STEARATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		DISTEARYLDIMONIUM CHLORIDE, EDTA, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL, CASTOR OIL, DMDM HYDANTOIN, STEARYL ALCOHOL
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, PEG-40 STEARATE, SODIUM HYDROXIDE, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show skin irritation at low doses		BENZALKONIUM CHLORIDE, BENZYL ALCOHOL, BHT, CETEARETH-20, CETEARETH-6, ISOPROPYL PALMITATE, METHYLDIBROMO GLUTARONITRILE, METHYLPARABEN, OCTISALATE, STEARIC ACID, SYNTHETIC WAX, TETRASODIUM EDTA, BENZALDEHYDE
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN, CITRIC ACID, CYCLOMETHICONE, GLYCERIN, MINERAL OIL, SODIUM CHLORIDE, SORBITAN STEARATE
One or more animal studies show skin irritation at high doses		IODOPROPYNYL BUTYLCARBAMATE, SODIUM BENZOATE
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), BENZYL ALCOHOL, TETRASODIUM EDTA, BENZALDEHYDE
Allowed workplace exposures restricted to low doses		BHT, SYNTHETIC WAX
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MINERAL OIL, TRIETHANOLAMINE
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CITRIC ACID, CYCLOMETHICONE, GLYCERIN, SODIUM BENZOATE, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE