Pantene || Skin Deep: Cosmetic Safety Reviews

BRAND: Pantene

Manufacturer: Procter & Gamble

BRAND SUMMARY

product score range	1	to	9
product count	238 (browse)
ingredient count	157
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company conducts animal tests.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this brand -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this brand:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this brand: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 238 products by Pantene

Product type(s) by this brand in Skin Deep: conditioner (53), hair color and bleaching (1), hair spray (7), mask (1), shampoo (53), styling gel/lotion (8), styling mousse/foam (7)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	5 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
DMDM HYDANTOIN	9	71%	14 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
OXYBENZONE (BENZOPHENONE-3)	9	55%	6 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	111 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-20	5	71%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	6	65%	4 products	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
CYCLOHEXYLAMINE	7	64%	1 products	Developmental/reproductive toxicity, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BUTANE	6	79%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards
ISOBUTANE	6	79%	8 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards
PEG-12	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-14M	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-2M	4	76%	6 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-60 ALMOND GLYCERIDES	4	76%	4 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-7M	4	76%	23 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-12 DIMETHICONE	4	75%	6 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 HYDROGENATED CASTOR OIL	4	75%	4 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PEG/ PPG-18/ 18 DIMETHICONE	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 DIMETHICONE	4	74%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
EXT D&C VIOLET 2	5	73%	1 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
IODOPROPYNYL BUTYLCARBAMATE	4	65%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BENZYL ALCOHOL	6	64%	38 products	Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
METHYLCHLOROISOTHIAZOLINONE	6	63%	86 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	83 products	Violations, restrictions & warnings, Allergies/immunotoxicity
TRIETHANOLAMINE	6	58%	4 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
LAURETH-23	5	83%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
D&C ORANGE 4	2	72%	4 products	Developmental/reproductive toxicity
ALCOHOL DENATURED	5	71%	5 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PROPYLPARABEN	5	71%	4 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
LACTIC ACID	4	70%	1 products	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs)
TRIISOPROPANOLAMINE	4	69%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES)
COCAMIDOPROPYL BETAINE	5	63%	4 products	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
PROPRIETARY INGREDIENTS	4	100%	7 products	Miscellaneous
SODIUM LAURETH SULFATE	4	88%	9 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
CETETH-20	3	84%	1 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TOCOPHERYL ACETATE	4	81%	6 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PROPANE	4	77%	7 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards
SD ALCOHOL 1	4	77%	3 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
COCAMIDE MEA	2	75%	46 products	Contamination concerns (NITROSAMINES)
D&C RED 33	1	75%	7 products	none identified
FD&C RED 4	1	73%	7 products	none identified
MINERAL OIL	2	73%	3 products	Organ system toxicity (non-reproductive), Occupational hazards
FD&C YELLOW 6	1	70%	2 products	none identified
OCTISALATE	3	68%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PHENOXYETHANOL	4	67%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	13 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
CETETH-10 PHOSPHATE	3	99%	2 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT	3	89%	3 products	Allergies/immunotoxicity, Multiple, additive exposure sources
AMMONIUM LAURETH-9 SULFATE	3	89%	2 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
AMMONIUM LAURETH SULFATE	3	87%	42 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
FD&C YELLOW 5	2	82%	6 products	Neurotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE	2	79%	42 products	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	62 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	3	78%	33 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	4 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ACRYLATES COPOLYMER	3	75%	7 products	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
DIMETHICONE	2	74%	83 products	Violations, restrictions & warnings
CITRIC ACID	2	72%	65 products	Violations, restrictions & warnings
CETRIMONIUM CHLORIDE	3	71%	3 products	Allergies/immunotoxicity
SODIUM LAURYL SULFATE	3	68%	9 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
HYDROGENATED POLYDECENE	2	94%	18 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
PETROLATUM	2	94%	4 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
PANTHENOL	2	88%	114 products	Multiple, additive exposure sources
GLUTAMIC ACID	2	85%	28 products	Organ system toxicity (non-reproductive), Biochemical or cellular level changes
FD&C BLUE 1	1	83%	13 products	none identified
DIMETHYL ETHER	1	81%	3 products	none identified
TETRASODIUM EDTA	2	81%	8 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
PARAFFIN	2	80%	3 products	Organ system toxicity (non-reproductive), Occupational hazards
POLYSORBATE-80	2	80%	4 products	Developmental/reproductive toxicity
POTASSIUM HYDROXIDE	2	80%	4 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PPG-2 METHYL ETHER	2	80%	2 products	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Occupational hazards
JASMINUM OFFICINALE (JASMINE) EXTRACT	2	76%	1 products	Violations, restrictions & warnings
POLYAMINOPROPYL BIGUANIDE	2	76%	1 products	Violations, restrictions & warnings
GLYCERIN	2	74%	3 products	Organ system toxicity (non-reproductive), Occupational hazards
LAURIC ACID	1	74%	1 products	Neurotoxicity
ACETAMIDE MEA	1	73%	1 products	Contamination concerns (ACETAMIDE MEA)
AMINOMETHYL PROPANOL	2	71%	9 products	Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE)
SODIUM BENZOATE	2	69%	48 products	Organ system toxicity (non-reproductive)
MELISSA OFFICINALIS (LEMON BALM) LEAF EXTRACT	1	100%	3 products	Multiple, additive exposure sources
SALVIA OFFICINALIS (SAGE) LEAF EXTRACT	1	95%	1 products	none identified
BEHENTRIMONIUM CHLORIDE	0	94%	4 products	none identified
STEARAMIDOPROPYL DIMETHYLAMINE	0	94%	27 products	none identified
CETEARYL ALCOHOL	0	93%	9 products	none identified
GLYCOL DISTEARATE	1	93%	41 products	Multiple, additive exposure sources
HYDROFLUOROCARBON 152A	1	93%	1 products	Organ system toxicity (non-reproductive)
CARAMEL	1	92%	5 products	none identified
SORBITAN STEARATE	1	92%	3 products	none identified
CHITOSAN	1	91%	1 products	none identified
D&C GREEN 5	1	91%	1 products	none identified
AMMONIUM BENZOATE	1	90%	3 products	none identified
COCOS NUCIFERA (COCONUT) OIL	1	89%	8 products	none identified
DIISOBUTYL ADIPATE	1	88%	2 products	none identified
GLYCERYL MONOSTEARATE	1	88%	9 products	none identified
SODIUM XYLENE SULFONATE	1	88%	9 products	none identified
TRIDECETH-12	1	88%	2 products	Organ system toxicity (non-reproductive)
C9-11 PARETH-8	1	87%	6 products	Organ system toxicity (non-reproductive)
CETYL ALCOHOL	1	87%	77 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE	1	87%	8 products	Organ system toxicity (non-reproductive)
LYSINE HYDROCHLORIDE	1	87%	26 products	none identified
OLEYL ALCOHOL	1	87%	6 products	Irritation (skin, eyes, or lungs)
SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL	1	87%	8 products	none identified
TRIETHYL CITRATE	1	87%	3 products	none identified
TRIMETHYLOLPROPANE	1	87%	2 products	Organ system toxicity (non-reproductive)
QUATERNIUM-18	1	85%	6 products	Organ system toxicity (non-reproductive)
POLYSORBATE-20	1	84%	1 products	none identified
STEARYL ALCOHOL	1	84%	38 products	Irritation (skin, eyes, or lungs)
HYDROXYETHYLCELLULOSE	1	82%	8 products	none identified
HISTIDINE	1	81%	19 products	none identified
POLYSORBATE-60	1	81%	6 products	none identified
PVP	1	81%	3 products	Organ system toxicity (non-reproductive)
MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT	1	80%	1 products	Enhanced skin absorption
VP/ DIMETHYLAMINOETHYLMETHACRYLATE COPOLYMER	1	74%	1 products	none identified
AMMONIUM LAURYL SULFATE	1	73%	44 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ACRYLATES/ BEHENETH-25 METHACRYLATE COPOLYMER	0	100%	1 products	none identified
ACRYLATES/ OCTYLACRYLAMIDE COPOLYMER	0	100%	1 products	none identified
AVENA SATIVA (OAT) KERNEL PROTEIN	0	100%	4 products	none identified
BEHENAMIDOPROPYL DIMETHYLAMINE	0	100%	7 products	none identified
CHAMOMILLA RECUTITA (MATRICARIA)	0	100%	1 products	none identified
CHAMOMILLA RECUTITA (MATRICARIA) FLOWER EXTRACT	0	100%	2 products	none identified
DICETYL PHOSPHATE	0	100%	3 products	none identified
DIMETHICONOL	0	100%	1 products	none identified
FOENICULUM VULGARE (FENNEL) EXTRACT	0	100%	1 products	none identified
FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT	0	100%	2 products	none identified
GLYCERETH-7-TRIACETATE	0	100%	1 products	none identified
HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT	0	100%	1 products	none identified
KERATIN AMINO ACIDS	0	100%	1 products	none identified
LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE	0	100%	3 products	none identified
MIPA-BORATE	0	100%	1 products	none identified
PANTHENYL ETHYL ETHER	0	100%	106 products	none identified
PPG-2 HYDROXYETHYL COCO/ ISOSTEARAMIDE	0	100%	4 products	none identified
ROSA CANINA (DOG ROSE) FRUIT EXTRACT	0	100%	1 products	none identified
ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT	0	100%	4 products	none identified
SODIUM LAUROAMPHOACETATE	0	100%	1 products	none identified
TRICAPRYLATE/ TRICAPRATE	0	100%	2 products	none identified
TRIMETHYLOLPROPANE TRICAPRYLATE/ TRICAPRATE	0	100%	16 products	none identified
VA CROTONATES/ VINYL NEODECANOATE COPOLYMER	0	100%	3 products	none identified
ACHILLEA MILLEFOLIUM (COMMON YARROW)	0	100%	1 products	none identified
HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT	0	100%	3 products	none identified
METHYL TYROSINATE HCL	0	100%	26 products	none identified
NARCISSUS JONQUILLA EXTRACT	0	100%	1 products	none identified
PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT	0	100%	2 products	none identified
CHAMOMILLA RECUTITA FLOWER/LEAF EXTRACT	0	100%	1 products	none identified
AMODIMETHICONE	0	99%	3 products	none identified
ISODECYL OLEATE	0	99%	3 products	none identified
AMMONIUM XYLENE-SULFONATE	0	94%	41 products	none identified
GLYCINE SOJA PROTEIN	0	94%	1 products	none identified
HUMULUS LUPULUS (HOPS) EXTRACT	0	94%	4 products	none identified
MEA-BORATE	0	94%	1 products	none identified
POLYQUATERNIUM-4	0	94%	7 products	none identified
PRUNUS SEROTINA (WILD CHERRY) EXTRACT	0	94%	3 products	none identified
SODIUM CITRATE	0	94%	50 products	none identified
CARBOMER	0	93%	1 products	none identified
POLYQUATERNIUM-10	0	93%	35 products	none identified
POLYQUATERNIUM-11	0	93%	2 products	none identified
TRIHYDROXYSTEARIN	0	93%	1 products	none identified
SODIUM CHLORIDE	0	0%	53 products	innocuous
WATER	0	0%	114 products	innocuous

* Product counts only include current formulations sold by this brand. The brand may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this brand that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - not classifiable/not likely to be human carcinogen		FD&C BLUE 1, FD&C RED 4, FD&C YELLOW 6, PVP, TRIETHANOLAMINE
Not likely to be carcinogenic in humans		LAURIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		ALCOHOL DENATURED, EXT D&C VIOLET 2, SD ALCOHOL 1
Cancer - not classifiable/not likely to be human carcinogen		LACTIC ACID
One or more in vitro tests on mammalian cells show positive mutation results		BENZYL ALCOHOL, CARAMEL, CETRIMONIUM CHLORIDE, CYCLOHEXYLAMINE, D&C ORANGE 4, DISODIUM EDTA, EDTA, FD&C YELLOW 5, GLUTAMIC ACID, GLYCERIN, HISTIDINE, METHYLPARABEN, POLYSORBATE-80, POTASSIUM HYDROXIDE, PROPYLENE GLYCOL, PROPYLPARABEN, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, SODIUM BENZOATE, SODIUM CHLORIDE, SODIUM HYDROXIDE, SODIUM LAURYL SULFATE, TOCOPHERYL ACETATE
One or more animal studies show tumor formation at moderate doses		PARAFFIN, PEG-100 STEARATE,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests non-mammalian cells show positive mutation results		D&C RED 33, HYDROFLUOROCARBON 152A, LAURETH-23, METHYLCHLOROISOTHIAZOLINONE, OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL
One or more animal studies show tumor formation at high doses		POLYSORBATE-60, STEARYL ALCOHOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		PPG-2 METHYL ETHER, SD ALCOHOL 1
One or more animal studies show reproductive effects at very low doses		POLYSORBATE-80
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		CYCLOHEXYLAMINE, D&C ORANGE 4
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3), ALCOHOL DENATURED
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, PROPYLENE GLYCOL,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at high doses		BENZYL ALCOHOL, DIISOBUTYL ADIPATE, DIMETHYL ETHER, DISODIUM EDTA, EDTA, FD&C YELLOW 5, HYDROXYETHYLCELLULOSE, POLYSORBATE-20, POLYSORBATE-60, SODIUM BENZOATE, SODIUM LAURYL SULFATE, PEG-100 STEARATE, FD&C YELLOW 6

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	products for use around the mouth, lips, eyes, or on damaged skin	D&C ORANGE 4, EXT D&C VIOLET 2, FD&C RED 4
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C RED 33, FD&C YELLOW 6
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		LACTIC ACID
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	products that may be aerosolized (airborne)	COCAMIDE MEA, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-20, PEG-12, PEG-12 DIMETHICONE, PEG-14M, PEG-2M, PEG-40 HYDROGENATED CASTOR OIL, PEG-60 ALMOND GLYCERIDES, PEG-7M, PEG-8 DIMETHICONE, PEG/ PPG-18/ 18 DIMETHICONE, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE, OCTISALATE, OXYBENZONE (BENZOPHENONE-3), POLYAMINOPROPYL BIGUANIDE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		CITRIC ACID, LACTIC ACID, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)		JASMINUM OFFICINALE (JASMINE) EXTRACT, BENZYL ALCOHOL, DIMETHICONE, EXT D&C VIOLET 2
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics		D&C RED 33, ACETAMIDE MEA, ACRYLATES COPOLYMER, AMINOMETHYL PROPANOL, AMMONIUM LAURYL SULFATE, BENZYL ALCOHOL, CETEARETH-20, CETRIMONIUM CHLORIDE, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, EXT D&C VIOLET 2, IODOPROPYNYL BUTYLCARBAMATE, LACTIC ACID, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, PEG-12, PEG-12 DIMETHICONE, PEG-14M, PEG-2M, PEG-40 HYDROGENATED CASTOR OIL, PEG-60 ALMOND GLYCERIDES, PEG-7M, PEG-8 DIMETHICONE, PEG/ PPG-18/ 18 DIMETHICONE, PROPYLENE GLYCOL, SODIUM BENZOATE, SODIUM LAURYL SULFATE, TRIETHANOLAMINE, TRIISOPROPANOLAMINE, VP/ DIMETHYLAMINOETHYLMETHACRYLATE COPOLYMER, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		BENZYL ALCOHOL
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		CYCLOHEXYLAMINE, FD&C YELLOW 5, SODIUM HYDROXIDE
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA, LAURETH-23, LAURIC ACID
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at moderate doses		AMINOMETHYL PROPANOL, AMMONIUM BENZOATE, C9-11 PARETH-8, CETEARETH-20, EDTA, GLUTAMIC ACID, MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT, METHYLPARABEN, PHENOXYETHANOL, QUATERNIUM-18, SODIUM BENZOATE, SODIUM LAURYL SULFATE
One or more animal studies show brain and nervous system effects at high doses		CETETH-20, FD&C BLUE 1, FD&C YELLOW 6, GLYCERIN, GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, HISTIDINE, HYDROXYETHYLCELLULOSE, LACTIC ACID, LYSINE HYDROCHLORIDE, OXYBENZONE (BENZOPHENONE-3), POLYSORBATE-80, PROPYLENE GLYCOL, TRIETHYL CITRATE, TRIISOPROPANOLAMINE, TRIMETHYLOLPROPANE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		PPG-2 METHYL ETHER, PROPANE, SD ALCOHOL 1
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show endocrine system disruption at high doses		ALCOHOL DENATURED, DISODIUM EDTA, GLYCERIN, HISTIDINE, MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT, PVP, SODIUM LAURYL SULFATE, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		COCAMIDOPROPYL BETAINE, CYCLOHEXYLAMINE, DMDM HYDANTOIN, FRAGRANCE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Human any toxicant - strong evidence		BUTANE, IODOPROPYNYL BUTYLCARBAMATE, ISOBUTANE, PROPANE, ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, CETRIMONIUM CHLORIDE, EXT D&C VIOLET 2, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE, TRIISOPROPANOLAMINE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more human case studies show possible allergenic effects		BENZYL ALCOHOL, OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of skin and immune system toxicity		PHENOXYETHANOL

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOPENTASILOXANE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		ACETAMIDE MEA, AMINOMETHYL PROPANOL, AMMONIUM BENZOATE, AMMONIUM LAURETH SULFATE, AMMONIUM XYLENE-SULFONATE, BEHENTRIMONIUM CHLORIDE, CETEARETH-20, CETEARYL ALCOHOL, CETETH-20, CETRIMONIUM CHLORIDE, CITRIC ACID, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, DIISOBUTYL ADIPATE, DIMETHICONE, DISODIUM EDTA, DMDM HYDANTOIN, FD&C RED 4, FD&C YELLOW 6, GLUTAMIC ACID, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCOL DISTEARATE, HISTIDINE, IODOPROPYNYL BUTYLCARBAMATE, LACTIC ACID, LAURIC ACID, LYSINE HYDROCHLORIDE, MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, METHYLPARABEN, OCTISALATE, OLEYL ALCOHOL, PANTHENOL, PEG-8 DIMETHICONE, PHENOXYETHANOL, POLYQUATERNIUM-4, PROPYLPARABEN, SODIUM BENZOATE, SODIUM CITRATE, SODIUM XYLENE SULFONATE, SORBITAN STEARATE, STEARAMIDOPROPYL DIMETHYLAMINE, STEARYL ALCOHOL, TRIETHYL CITRATE, TRIHYDROXYSTEARIN, AMMONIUM LAURETH-9 SULFATE, PEG-100 STEARATE
Not suspected to be persistent		C9-11 PARETH-8, CETYL ALCOHOL, LAURETH-23, QUATERNIUM-18, SODIUM LAURYL SULFATE, TRIDECETH-12
Not suspected to be bioaccumulative		CARBOMER, COCOS NUCIFERA (COCONUT) OIL, D&C GREEN 5, D&C ORANGE 4, D&C RED 33, DIMETHYL ETHER, EXT D&C VIOLET 2, FD&C BLUE 1, FD&C YELLOW 5, HYDROFLUOROCARBON 152A, MEA-BORATE, POLYQUATERNIUM-11, SODIUM CHLORIDE, TOCOPHERYL ACETATE, TRIISOPROPANOLAMINE, VP/ DIMETHYLAMINOETHYLMETHACRYLATE COPOLYMER, WATER
Not suspected to be bioaccumulative		ALCOHOL DENATURED, BUTANE, EDTA, HYDROGENATED POLYDECENE, ISOBUTANE, PETROLATUM, POTASSIUM HYDROXIDE, PROPANE, PVP, SODIUM HYDROXIDE, TRIETHANOLAMINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE, TRIETHANOLAMINE
One or more animal studies show cardiovascular effects at very low doses		GLUTAMIC ACID, GLYCERIN, SODIUM HYDROXIDE, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	CYCLOHEXYLAMINE
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ACETAMIDE MEA, ALCOHOL DENATURED, CITRIC ACID, LACTIC ACID, LAURETH-23, PHENOXYETHANOL, SODIUM LAURETH SULFATE, TRIISOPROPANOLAMINE
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, EDTA, SODIUM BENZOATE, SODIUM LAURYL SULFATE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	AMMONIUM LAURYL SULFATE, CETEARETH-20, MINERAL OIL, POTASSIUM HYDROXIDE, SODIUM CHLORIDE
Classified as toxic or harmful	products for use around the mouth; products for use on the lips; products that may be aerosolized (airborne)	BENZYL ALCOHOL
Limited evidence of cardiovascular or blood toxicity		HYDROFLUOROCARBON 152A, IODOPROPYNYL BUTYLCARBAMATE, SD ALCOHOL 1, PPG-2 METHYL ETHER, PEG-12, PEG-12 DIMETHICONE, PEG-14M, PEG-2M, PEG-40 HYDROGENATED CASTOR OIL, PEG-60 ALMOND GLYCERIDES, PEG-7M, PEG-8 DIMETHICONE, PEG/ PPG-18/ 18 DIMETHICONE, PROPYLPARABEN, PEG-100 STEARATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		AMMONIUM LAURETH SULFATE, CETRIMONIUM CHLORIDE, DMDM HYDANTOIN, GLYCERYL MONOSTEARATE, OCTISALATE, POLYSORBATE-60, PVP, TOCOPHERYL ACETATE, AMMONIUM LAURETH-9 SULFATE,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3), FD&C BLUE 1, PROPANE
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		C9-11 PARETH-8, QUATERNIUM-18,
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	AMINOMETHYL PROPANOL, MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CETYL ALCOHOL, CYCLOPENTASILOXANE, D&C GREEN 5, LAURIC ACID, OLEYL ALCOHOL, PARAFFIN, POLYSORBATE-80, STEARYL ALCOHOL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		CETETH-20, PANTHENOL, HYDROXYETHYLCELLULOSE, FD&C YELLOW 6, POLYSORBATE-20, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, CHITOSAN, COCOS NUCIFERA (COCONUT) OIL, D&C ORANGE 4, HISTIDINE, SODIUM XYLENE SULFONATE, TRIDECETH-12,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, LYSINE HYDROCHLORIDE, TRIETHYL CITRATE, TRIMETHYLOLPROPANE
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as expected to be toxic or harmful		BUTANE, HYDROGENATED POLYDECENE, ISOBUTANE, PETROLATUM
Classified as not expected to be potentially toxic or harmful		AMMONIUM BENZOATE, AMMONIUM XYLENE-SULFONATE, BEHENTRIMONIUM CHLORIDE, CARAMEL, CARBOMER, CETEARYL ALCOHOL, COCAMIDE MEA, COCAMIDOPROPYL BETAINE, D&C RED 33, DIISOBUTYL ADIPATE, DIMETHYL ETHER, EXT D&C VIOLET 2, FD&C RED 4, GLYCINE SOJA PROTEIN, GLYCOL DISTEARATE, HUMULUS LUPULUS (HOPS) EXTRACT, MEA-BORATE, METHYLISOTHIAZOLINONE, POLYQUATERNIUM-10, POLYQUATERNIUM-11, POLYQUATERNIUM-4, PRUNUS SEROTINA (WILD CHERRY) EXTRACT, SODIUM CITRATE, SORBITAN STEARATE, STEARAMIDOPROPYL DIMETHYLAMINE, TRIHYDROXYSTEARIN, VP/ DIMETHYLAMINOETHYLMETHACRYLATE COPOLYMER, WATER

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE, PROPRIETARY INGREDIENTS
Occupational hazards related to handling		ALCOHOL DENATURED, BUTANE, CYCLOHEXYLAMINE, DIMETHYL ETHER, ISOBUTANE, POTASSIUM HYDROXIDE, PROPANE, SODIUM HYDROXIDE, SD ALCOHOL 1

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, ALCOHOL DENATURED, BUTANE, GLYCOL DISTEARATE, ISOBUTANE, MELISSA OFFICINALIS (LEMON BALM) LEAF EXTRACT, PANTHENOL, PROPANE, SD ALCOHOL 1
Designated as safe for general or specific, limited use in food		ALCOHOL DENATURED, BENZYL ALCOHOL, BUTANE, CARAMEL, CETYL ALCOHOL, CITRIC ACID, COCOS NUCIFERA (COCONUT) OIL, CYCLOHEXYLAMINE, DIMETHICONE, DISODIUM EDTA, FD&C BLUE 1, FD&C YELLOW 5, FD&C YELLOW 6, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, GLUTAMIC ACID, GLYCERIN, GLYCERYL MONOSTEARATE, HISTIDINE, HUMULUS LUPULUS (HOPS) EXTRACT, ISOBUTANE, LACTIC ACID, LAURETH-23, LAURIC ACID, METHYLPARABEN, MINERAL OIL, PARAFFIN, PEG-12, PEG-12 DIMETHICONE, PEG-14M, PEG-2M, PEG-40 HYDROGENATED CASTOR OIL, PEG-60 ALMOND GLYCERIDES, PEG-7M, PEG-8 DIMETHICONE, PEG/ PPG-18/ 18 DIMETHICONE, PETROLATUM, POLYSORBATE-20, POLYSORBATE-60, POLYSORBATE-80, POTASSIUM HYDROXIDE, PROPANE, PROPYLENE GLYCOL, PROPYLPARABEN, PRUNUS SEROTINA (WILD CHERRY) EXTRACT, PVP, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, SODIUM BENZOATE, SODIUM CHLORIDE, SODIUM CITRATE, SODIUM HYDROXIDE, SODIUM LAURYL SULFATE, SODIUM XYLENE SULFONATE, SORBITAN STEARATE, STEARYL ALCOHOL, TETRASODIUM EDTA, TOCOPHERYL ACETATE, TRIETHANOLAMINE, TRIETHYL CITRATE, PEG-100 STEARATE, PRUNUS SEROTINA (WILD CHERRY) FRUIT EXTRACT

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		AMINOMETHYL PROPANOL, EDTA, PHENOXYETHANOL, TRIISOPROPANOLAMINE, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	AMMONIUM LAURETH SULFATE, BUTANE, DMDM HYDANTOIN, ISOBUTANE, LAURETH-23, OLEYL ALCOHOL, PROPANE, SODIUM LAURETH SULFATE, SODIUM LAURYL SULFATE, STEARYL ALCOHOL
Human skin irritant - moderate evidence		CYCLOHEXYLAMINE
One or more animal studies show skin irritation at very low doses		AMMONIUM LAURYL SULFATE, CETYL ALCOHOL, LACTIC ACID, POTASSIUM HYDROXIDE, SODIUM HYDROXIDE, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, BENZYL ALCOHOL, CETEARETH-20, METHYLPARABEN, OCTISALATE, TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		ACETAMIDE MEA, CITRIC ACID, CYCLOPENTASILOXANE, D&C GREEN 5, GLYCERIN, LAURIC ACID, MATRICARIA RECUTITA (GERMAN CHAMOMILE) EXTRACT, MINERAL OIL, PARAFFIN, POLYSORBATE-20, PPG-2 METHYL ETHER, QUATERNIUM-18, SODIUM CHLORIDE, SORBITAN STEARATE, TRIDECETH-12
One or more animal studies show skin irritation at high doses		CETETH-20, IODOPROPYNYL BUTYLCARBAMATE, SODIUM BENZOATE, SODIUM XYLENE SULFONATE
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		BENZYL ALCOHOL, PHENOXYETHANOL, POTASSIUM HYDROXIDE, TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		PARAFFIN
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MINERAL OIL, TRIETHANOLAMINE
Allowed workplace exposures restricted to high doses		BUTANE, CYCLOHEXYLAMINE, ISOBUTANE, PPG-2 METHYL ETHER, PROPANE,
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED
No workplace limits set		LACTIC ACID, SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		GLUTAMIC ACID
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		LAURETH-23, SODIUM LAURYL SULFATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, CETETH-20, CHITOSAN, CITRIC ACID, CYCLOPENTASILOXANE, D&C GREEN 5, D&C ORANGE 4, GLYCERIN, HISTIDINE, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, SODIUM BENZOATE, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		METHYLPARABEN
Does not produces excess reactive oxygen species or other harmful biochemical changes.		OCTISALATE