Combe Inc. || Skin Deep: Cosmetic Safety Reviews

Manufacturer: Combe Inc.

Brands: Aqua Velva, Brylcreem, Cepacol, Grecian Formula, Johnson's Foot Soap, Just For Men, Lanacane, Maxim, Odor-Eaters, Scalpicin, Vagisil, Williams, Grecian, Gynecort, Just 5, Lanacort, Combe

COMPANY SUMMARY

product score range	2	to	10
product count	146		(browse)
ingredient count	258
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Ingredients used by this company:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this company: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. This chart indicates that research studies have found that exposure to one or more ingredients in products by this company -- not the products themselves -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

See all 146 products by Combe Inc.

Product type(s) by this company in Skin Deep: after shave (5), after sun product (1), anti-aging (1), anti-itch/rash cream (21), conditioner (2), dandruff/scalp treatment (5), facial moisturizer/treatment (1), feminine moisturizer (3), feminine powder/deodorant (2), foot odor control (3), fragrance for men (3), hair color and bleaching (84), hair growth inhibitor (1), lubricant/spermicide (2), mouthwash (6), pain relief (2), personal cleansing (3), shampoo (5), shaving cream (1), shaving cream (men's) (5), styling gel/lotion (7)

ingredients

	score	data gap	products *	concerns
OCTOXYNOL-40	9	68%	12 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS, ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS)
AMMONIUM PERSULFATE	7	59%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
RESORCINOL	8	55%	66 products	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROQUINONE	10	52%	2 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-PHENYLENEDIAMINE	10	52%	76 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
LEAD ACETATE	10	46%	9 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
CETEARETH-20	5	71%	12 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
PHENYLENEDIAMINE, M-	7	64%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHANOLAMINE	7	63%	53 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
BHT	7	61%	3 products	Neurotoxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
DMDM HYDANTOIN	7	61%	4 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
N-PHENYL-P-PHENYLENEDIAMINE	9	57%	8 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (NITROSAMINES)
O-AMINOPHENOL	8	57%	2 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
P-AMINOPHENOL	8	57%	58 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	124 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
TRICETEARETH 4 PHOSPHATE	4	75%	2 products	Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-7 GLYCERYL COCOATE	5	74%	2 products	Organ system toxicity (non-reproductive), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
OCTOXYNOL-9	8	68%	7 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (C9 PHENOLS, ETHYLENE OXIDE, 1,4-DIOXANE, C9 PHENOLS)
PEG-60	6	68%	3 products	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
SALICYLIC ACID	7	66%	1 products	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
HYDROGEN PEROXIDE	3	65%	57 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
METHYLPARABEN	8	65%	36 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
M-PHENYLENEDIAMINE	7	63%	20 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
1-NAPHTHOL	8	60%	29 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
SILICA	7	72%	12 products	Cancer, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PEG-100 STEARATE	7	68%	33 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TRICLOSAN	7	67%	2 products	Violations, restrictions & warnings, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (CHLOROFORM, DIOXIN)
POTASSIUM PERSULFATE	5	66%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
SULFURIC ACID	5	65%	2 products	Cancer, Organ system toxicity (non-reproductive), Occupational hazards
BENZOCAINE	7	61%	11 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
PROPYLENE GLYCOL	4	58%	47 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM BORATE	6	51%	3 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Occupational hazards
SODIUM LAURETH SULFATE	4	85%	17 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
ZINC OXIDE (NON-NANO)	1	81%	3 products	Persistence and bioaccumulation, Occupational hazards
ISOBUTANE	5	79%	2 products	Allergies/immunotoxicity, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards
PEG-20 CORN GLYCERIDES	4	76%	2 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
DIMETHICONE PEG-7 ISOSTEARATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-60 HYDROGENATED CASTOR OIL	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ACETIC ACID	2	73%	9 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
D&C VIOLET 2	4	73%	3 products	Cancer, Violations, restrictions & warnings
EXT D&C VIOLET 2	6	73%	9 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
POLYOXYMETHYLENE UREA	6	73%	1 products	Violations, restrictions & warnings, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (FORMALDEHYDE)
IODOPROPYNYL BUTYLCARBAMATE	4	72%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
4-CHLORORESORCINOL	5	69%	45 products	Cancer, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity
SODIUM PERSULFATE	5	69%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
OCTINOXATE (OCTYL METHOXYCINNAMATE)	4	66%	1 products	Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
M-AMINOPHENOL	6	65%	73 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
ZINC PYRITHIONE	5	64%	15 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
DIAZOLIDINYL UREA	6	59%	18 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	12 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
LAURETH-23	5	81%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
BUTYLPARABEN	5	79%	1 products	Developmental/reproductive toxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
SD ALCOHOL 40	5	77%	9 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN)
MINERAL OIL	5	73%	26 products	Cancer, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
ALCOHOL DENATURED	5	72%	4 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
ETHANOL	5	72%	1 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
POLYACRYLAMIDE	2	71%	1 products	Contamination concerns (ACRYLAMIDE)
D&C ORANGE 4	5	70%	4 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
RETINYL PALMITATE	5	70%	11 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
VITAMIN A	5	70%	5 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
4-AMINO-2-HYDROXYTOLUENE	5	68%	2 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
PHENYL METHYL PYRAZOLONE	5	68%	21 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity
VITAMIN D2	5	68%	4 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
UNSPECIFIED FLAVOR	4	100%	4 products	Miscellaneous
FLAVOR	4	100%	2 products	Miscellaneous
PROPYLPARABEN	4	82%	32 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
TITANIUM DIOXIDE (NON-NANO)	1	82%	8 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
POLOXAMER 234	1	82%	2 products	Organ system toxicity (non-reproductive)
POLOXAMER 334	1	82%	2 products	Organ system toxicity (non-reproductive)
POLOXAMER 407	1	82%	2 products	Organ system toxicity (non-reproductive)
SD ALCOHOL 40B	4	81%	11 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
TOCOPHERYL ACETATE	4	81%	100 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
TETRASODIUM EDTA	1	80%	1 products	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
HYDROCORTISONE ACETATE	4	79%	8 products	Developmental/reproductive toxicity, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PARAFFIN	1	79%	2 products	Occupational hazards
DIOCTYL SODIUM SULFOSUCCINATE	2	78%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PROPANE	4	78%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards
ETHOXYDIGLYCOL	1	77%	44 products	Organ system toxicity (non-reproductive)
ISOPROPYL ALCOHOL	4	76%	6 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
AMMONIUM CHLORIDE	3	75%	5 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
COCAMIDE MEA	2	75%	21 products	Contamination concerns (NITROSAMINES)
FD&C GREEN 3	1	73%	2 products	none identified
FD&C RED 4	4	73%	3 products	Violations, restrictions & warnings
SODIUM POLYACRYLATE	4	73%	1 products	Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
CITRIC ACID	4	72%	17 products	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive)
GUAIAZULENE	1	72%	1 products	Organ system toxicity (non-reproductive)
VEGETABLE FATTY ACID	4	72%	30 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
TOLNAFTATE	4	71%	1 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
BENZETHONIUM CHLORIDE	4	70%	13 products	Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 6	1	70%	10 products	none identified
LAURAMIDE DEA	2	70%	18 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES)
SULISOBENZONE (BENZOPHENONE-4)	3	69%	4 products	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
SODIUM METASILICATE	4	64%	2 products	Developmental/reproductive toxicity, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs)
CHOLECALCIFEROL	4	61%	11 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Occupational hazards
ISOLAURETH-6	3	100%	12 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
LAURETH-7	3	100%	1 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CETETH-10 PHOSPHATE	3	99%	2 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OLETH-3	3	99%	10 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
LAURETH-4	3	96%	24 products	Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
POLYQUATERNIUM-5	1	94%	2 products	Multiple, additive exposure sources
PETROLATUM	1	92%	2 products	Contamination concerns (PAHS)
WHITE PETROLATUM	1	92%	1 products	Contamination concerns (PAHS)
LANOLIN ALCOHOL	2	87%	3 products	Allergies/immunotoxicity
MENTHOL	3	85%	7 products	Organ system toxicity (non-reproductive), Multiple, additive exposure sources
SODIUM SULFITE	3	84%	81 products	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5	2	82%	6 products	Neurotoxicity, Organ system toxicity (non-reproductive)
SACCHARIN	3	81%	4 products	Cancer, Developmental/reproductive toxicity, Multiple, additive exposure sources
ANTHEMIS NOBILIS (CHAMOMILE)	3	80%	2 products	Multiple, additive exposure sources, Enhanced skin absorption
BENZOPHENONE-1	3	79%	7 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
BENZOPHENONE-2	3	79%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
CYCLOPENTASILOXANE	2	79%	1 products	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	21 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
EDTA	2	78%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
MICA	3	75%	7 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
DIMETHICONE	2	74%	18 products	Violations, restrictions & warnings
2-METHYL-5-HYDROXYETHYLAMINOPHENOL	3	73%	2 products	Cancer, Allergies/immunotoxicity
D&C YELLOW 10	3	73%	6 products	Violations, restrictions & warnings
1,2,4-TRIHYDROXYBENZENE	3	73%	2 products	Cancer, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
STEARIC ACID	2	72%	5 products	Neurotoxicity, Irritation (skin, eyes, or lungs)
GLYCERYL MONOSTEARATE	3	71%	35 products	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (GLYCERYL DIESTERS)
AMINOMETHYL PROPANOL	3	69%	26 products	Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE)
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE	3	69%	40 products	Cancer, Allergies/immunotoxicity
SODIUM LAURYL SULFATE	2	68%	18 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PANTHENOL	2	88%	92 products	Multiple, additive exposure sources
ACETYLATED LANOLIN ALCOHOL	2	87%	13 products	Allergies/immunotoxicity
TOCOPHEROL	2	87%	4 products	Contamination concerns (HYDROQUINONE)
CALCIUM HYDROXIDE	1	85%	2 products	Occupational hazards
2-METHYLRESORCINOL	2	84%	18 products	Allergies/immunotoxicity
CYCLOMETHICONE	1	83%	1 products	Persistence and bioaccumulation
FD&C BLUE 1	1	83%	5 products	none identified
MAGNESIUM SULFATE	2	82%	2 products	Organ system toxicity (non-reproductive)
TETRASODIUM PYROPHOSPHATE	2	82%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
POLYSORBATE-80	2	80%	6 products	Developmental/reproductive toxicity
ETIDRONIC ACID	2	79%	2 products	Endocrine disruption, Organ system toxicity (non-reproductive)
ZEA MAYS (CORN) OIL	2	79%	11 products	Neurotoxicity
SODIUM BICARBONATE	2	78%	6 products	none identified
SODIUM SACCHARIN	2	78%	2 products	Neurotoxicity
CHOLESTEROL	2	74%	2 products	Persistence and bioaccumulation
GLYCERIN	2	74%	39 products	Organ system toxicity (non-reproductive), Occupational hazards
HYDROGENATED LECITHIN	2	74%	1 products	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
ACETAMIDE MEA	1	73%	10 products	Contamination concerns (ACETAMIDE MEA)
CETYLPYRIDINIUM CHLORIDE	2	73%	5 products	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs)
CITRUS GRANDIS (GRAPEFRUIT) FRUIT EXTRACT	1	100%	1 products	Multiple, additive exposure sources
HYDROLYZED WHEAT PROTEIN	1	95%	5 products	Allergies/immunotoxicity
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	1 products	none identified
MYRISTYL PROPIONATE	0	94%	2 products	none identified
SODIUM TALLOWATE	0	94%	1 products	none identified
HYPERICUM PERFORATUM (ST. JOHN'S WORT) EXTRACT	1	94%	1 products	none identified
C13-14 ISOPARAFFIN	1	93%	1 products	none identified
CETEARYL ALCOHOL	0	93%	12 products	none identified
CETYL ACETATE	1	93%	13 products	none identified
GLUCONOLACTONE	1	93%	2 products	none identified
MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL	1	93%	3 products	Endocrine disruption, Allergies/immunotoxicity
MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA)	0	93%	1 products	none identified
PHENYL TRIMETHICONE	0	93%	1 products	none identified
HAIR KERATIN AMINO ACIDS	0	93%	2 products	none identified
CARAMEL	1	92%	18 products	none identified
ISOPROPYL PALMITATE	1	92%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SORBITAN STEARATE	1	92%	11 products	none identified
DENATONIUM BENZOATE	1	90%	5 products	none identified
ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT	1	90%	1 products	none identified
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	11 products	none identified
ISOPROPYL STEARATE	1	89%	3 products	Irritation (skin, eyes, or lungs)
SODIUM GLUCONATE	1	89%	2 products	none identified
SODIUM PHOSPHATE	1	89%	4 products	none identified
TETRASODIUM ETIDRONATE	1	89%	1 products	none identified
VP/ VA COPOLYMER	1	89%	4 products	none identified
STEARETH-21	1	89%	2 products	none identified
LINOLEIC ACID	1	88%	11 products	Irritation (skin, eyes, or lungs)
SODIUM STANNATE	1	88%	2 products	Occupational hazards
C11-15 PARETH-3	1	88%	20 products	Organ system toxicity (non-reproductive)
C11-15 PARETH-9	1	88%	2 products	Organ system toxicity (non-reproductive)
DIMETHYL OXAZOLIDINE	1	88%	2 products	none identified
CETYL ALCOHOL	1	87%	49 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DISODIUM COCOAMPHODIACETATE	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ERYTHORBIC ACID	1	87%	79 products	none identified
ISOPROPYL MYRISTATE	1	87%	19 products	Irritation (skin, eyes, or lungs)
OLEYL ALCOHOL	1	87%	41 products	Irritation (skin, eyes, or lungs)
SODIUM CITRATE	1	87%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive)
D&C GREEN 5	1	86%	4 products	none identified
DISODIUM PHOSPHATE	1	86%	3 products	none identified
SULFUR	1	86%	9 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
TRISODIUM EDTA	1	86%	79 products	Enhanced skin absorption
DIPROPYLENE GLYCOL	1	85%	1 products	Irritation (skin, eyes, or lungs)
POTASSIUM STEARATE	1	85%	1 products	Occupational hazards
STEARALKONIUM CHLORIDE	1	85%	10 products	Organ system toxicity (non-reproductive)
1-DODECANOL	1	84%	13 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL	1	84%	4 products	none identified
HYDROXYPROPYL METHYLCELLULOSE	1	84%	3 products	none identified
STEARYL ALCOHOL	1	84%	2 products	Irritation (skin, eyes, or lungs)
ZEA MAYS (CORN) STARCH	1	83%	5 products	Occupational hazards
HYDROXYETHYLCELLULOSE	1	82%	2 products	none identified
POLYSORBATE-20	1	81%	5 products	none identified
PVP	1	81%	4 products	Organ system toxicity (non-reproductive)
ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT	1	80%	14 products	Enhanced skin absorption
BISABOLOL	1	80%	1 products	Enhanced skin absorption
MAGNESIUM STEARATE	1	80%	3 products	Occupational hazards
ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT	1	80%	61 products	Enhanced skin absorption
ISOPROPYL ACETATE	1	79%	2 products	Irritation (skin, eyes, or lungs), Occupational hazards
2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE	1	76%	12 products	Cancer
CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT	1	76%	3 products	none identified
2,4-DIAMINOPHENOXYETHANOL SULFATE	1	76%	7 products	Cancer
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT	1	75%	80 products	none identified
PENTASODIUM PENTETATE	0	74%	1 products	none identified
4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL	1	73%	3 products	none identified
SODIUM SULFATE	1	73%	1 products	none identified
ALOE BARBADENSIS (ALOE VERA)	1	72%	18 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	6 products	none identified
ALLYL METHACRYLATES CROSSPOLYMER	0	100%	1 products	none identified
BEHENTRIMONIUM METHOSULFATE	0	100%	2 products	none identified
BIS-P-PHENYLENEDIAMINE SULFATE	0	100%	2 products	none identified
CENTAUREA (MILLER)	0	100%	2 products	none identified
CERAMIDE 2	0	100%	1 products	none identified
CERAMIDE 3	0	100%	1 products	none identified
CINNAMIDOPROPYLTRIMONIUM CHLORIDE	0	100%	22 products	none identified
CITRUS PARADISI (GRAPEFRUIT) EXRACT	0	100%	2 products	none identified
COCO-GLUCOSIDE	0	100%	20 products	none identified
DECYL GLUCOSIDE	0	100%	2 products	none identified
DICETYL PHOSPHATE	0	100%	2 products	none identified
DIMETHICONE CROSSPOLYMER	0	100%	1 products	none identified
DIMETHICONOL	0	100%	1 products	none identified
HYDROCORTISONE ALCOHOL	0	100%	2 products	none identified
LAURDIMONIUM HYDROXPROPYL HYDROLYZED WHEAT PROTEIN	0	100%	2 products	none identified
LAURDIMONIUM HYDROXYPROPYL HYDROLYZED WHEAT PROTEIN	0	100%	18 products	none identified
LAURYLDIMONIUM HYDROXYPROPYL HYDROLYZED WHEAT PROTEIN	0	100%	16 products	none identified
MILKAMIDOPROPYL BETAINE	0	100%	9 products	none identified
MYRISTATE	0	100%	1 products	none identified
PANTHENYL HYDROXYPROPYL STEARDIMONIUM CHLORIDE	0	100%	10 products	none identified
PASSIFLORA INCARNATA (MAYPOPS) FLOWER EXTRACT	0	100%	1 products	none identified
PHYTOSPHINGOSINE	0	100%	1 products	none identified
POLYQUATERNIUM-22	0	100%	30 products	none identified
POLYSILOXY LINOLEYL PYROLIDONE PHOSPHOLIPID	0	100%	2 products	none identified
ROSA CANINA (DOG ROSE) EXTRACT	0	100%	1 products	none identified
SILYBUM MARIANUM (LADY'S THISTLE) FRUIT EXTRACT	0	100%	1 products	none identified
STARCH/ ACRYLATES/ ACRYLAMIDE COPOLYMER	0	100%	3 products	none identified
STEARAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE	0	100%	11 products	none identified
SUNFLOWER SEEDAMIDOPROPYL DIMETHYLAMINE LACTATE	0	100%	2 products	none identified
TRIMETHYLSILYLAMODIMETHICONE	0	100%	10 products	none identified
HYDROXYPROPYL METHYCELLULOSE	0	100%	3 products	none identified
CHAMOMILLA RECUTITA (MATRICARIA) LEAF EXTRACT	0	100%	1 products	none identified
DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE	0	100%	1 products	none identified
AMODIMETHICONE	0	99%	2 products	none identified
QUATERNIUM-18 HECTORITE	0	99%	1 products	none identified
BUTYROSPERMUM PARKII (SHEA BUTTER)	0	94%	1 products	none identified
HYDROLYZED ELASTIN	0	94%	4 products	none identified
VP/ EICOSENE COPOLYMER	0	94%	1 products	none identified
SODIUM COCOATE	0	94%	1 products	none identified
SULFATED CASTOR OIL	0	94%	3 products	none identified
TRICALCIUM PHOSPHATE	0	94%	4 products	none identified
BEESWAX	0	93%	2 products	none identified
CARBOMER	0	93%	37 products	none identified
GLYCERYL STEARATE SE	0	93%	3 products	none identified
HYDROGENATED CASTOR OIL	0	93%	3 products	none identified
POLYQUATERNIUM-10	0	93%	2 products	none identified
POLYQUATERNIUM-11	0	93%	4 products	none identified
TRISODIUM HEDTA	0	90%	6 products	Enhanced skin absorption
WATER	0	0%	137 products	innocuous

* Product counts only include current formulations sold by this company. The company may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this company that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human carcinogen		SULFURIC ACID
Possible human carcinogen		LEAD ACETATE
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
Limited evidence of carcinogenicity		HYDROQUINONE
Cancer - not classifiable/not likely to be human carcinogen	products that may be aerosolized (airborne)	SILICA
Cancer - not classifiable/not likely to be human carcinogen		BHT, CHOLESTEROL, FD&C BLUE 1, FD&C GREEN 3, FD&C RED 4, FD&C YELLOW 6, HYDROGEN PEROXIDE, ISOPROPYL ALCOHOL, P-PHENYLENEDIAMINE, PVP, RESORCINOL, SACCHARIN, TRIETHANOLAMINE, PHENYLENEDIAMINE, M-
Mutagen - limited evidence		M-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		1-NAPHTHOL, 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORORESORCINOL, ALCOHOL DENATURED, D&C VIOLET 2, ETHANOL, EXT D&C VIOLET 2, M-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, N-PHENYL-P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, RETINYL PALMITATE, SD ALCOHOL 40, SD ALCOHOL 40B, VITAMIN A, 1,2,4-TRIHYDROXYBENZENE, 2,4-DIAMINOPHENOXYETHANOL SULFATE
Cancer - not classifiable/not likely to be human carcinogen		SALICYLIC ACID, HYPERICUM PERFORATUM (ST. JOHN'S WORT) EXTRACT
One or more in vitro tests on mammalian cells show positive mutation results		ACETIC ACID, AMMONIUM CHLORIDE, BENZETHONIUM CHLORIDE, BENZOPHENONE-2, BUTYLPARABEN, CALCIUM HYDROXIDE, CARAMEL, D&C ORANGE 4, DIAZOLIDINYL UREA, DISODIUM EDTA, EDTA, ERYTHORBIC ACID, ETHANOLAMINE, FD&C YELLOW 5, GLYCERIN, HYDROCORTISONE ACETATE, MENTHOL, METHYLPARABEN, OCTOXYNOL-9, POLYSORBATE-80, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM BICARBONATE, SODIUM LAURYL SULFATE, SODIUM SACCHARIN, SODIUM SULFITE, TOCOPHEROL, TOCOPHERYL ACETATE, ZINC OXIDE (NON-NANO), DIMETHYL OXAZOLIDINE, OCTOXYNOL-40, PEG-60
One or more animal studies show tumor formation at moderate doses		PARAFFIN, PEG-100 STEARATE,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests non-mammalian cells show positive mutation results		ALOE BARBADENSIS (ALOE VERA), ETHOXYDIGLYCOL, GLUCONOLACTONE, LAURETH-23, MAGNESIUM SULFATE, POLYOXYMETHYLENE UREA, SODIUM BORATE, TRICLOSAN, TRITICUM VULGARE (WHEAT) GERM OIL
Not likely to be mutagenic in humans		SULISOBENZONE (BENZOPHENONE-4)
One or more animal studies show tumor formation at high doses		1-DODECANOL, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, LAURAMIDE DEA, STEARYL ALCOHOL, ZEA MAYS (CORN) OIL
Possible carcinogen		AMMONIUM PERSULFATE, DIOCTYL SODIUM SULFOSUCCINATE, PETROLATUM, POLYACRYLAMIDE, SODIUM LAURETH SULFATE, TETRASODIUM EDTA, WHITE PETROLATUM, ZINC PYRITHIONE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human reproductive toxicant		LEAD ACETATE
Limited evidence of reproductive toxicity		ETHANOL, SD ALCOHOL 40, SD ALCOHOL 40B, SODIUM BORATE
Human nervous system toxicant - moderate evidence		HYDROQUINONE, P-PHENYLENEDIAMINE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show reproductive effects at very low doses		HYDROCORTISONE ACETATE, POLYSORBATE-80, VITAMIN D2, PEG-60
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		D&C ORANGE 4, RETINYL PALMITATE, SODIUM METASILICATE, VITAMIN A
Limited evidence of developmental toxicity		ISOPROPYL ALCOHOL, SACCHARIN, ALCOHOL DENATURED
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		1-NAPHTHOL, CHOLECALCIFEROL, CHOLESTEROL, ETIDRONIC ACID, GLYCERIN, O-AMINOPHENOL, P-AMINOPHENOL, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM BICARBONATE, TOLNAFTATE, ZINC PYRITHIONE,
One or more animal studies show reproductive effects at moderate doses		ALOE BARBADENSIS (ALOE VERA), OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show developmental effects at high doses		ZINC OXIDE (NON-NANO)
One or more animal studies show reproductive effects at high doses		4-CHLORORESORCINOL, ACETIC ACID, BHT, DIOCTYL SODIUM SULFOSUCCINATE, DISODIUM EDTA, EDTA, ETHANOLAMINE, ETHOXYDIGLYCOL, FD&C YELLOW 5, HYDROXYETHYLCELLULOSE, M-AMINOPHENOL, M-PHENYLENEDIAMINE, MAGNESIUM SULFATE, N-PHENYL-P-PHENYLENEDIAMINE, OCTOXYNOL-9, PHENYL METHYL PYRAZOLONE, POLYSORBATE-20, SODIUM LAURYL SULFATE, SODIUM SACCHARIN, TRICLOSAN, ZEA MAYS (CORN) OIL, OCTOXYNOL-40, PEG-100 STEARATE, PHENYLENEDIAMINE, M-

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of government restrictions - Banned or found unsafe for use in cosmetics	product not intended as hair dye/bleach	HYDROGEN PEROXIDE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		BENZOCAINE, LEAD ACETATE, TOLNAFTATE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any		N-PHENYL-P-PHENYLENEDIAMINE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	products for use around the mouth, lips, eyes, or on damaged skin	D&C ORANGE 4, D&C VIOLET 2, EXT D&C VIOLET 2, FD&C RED 4
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C YELLOW 10, FD&C GREEN 3, FD&C YELLOW 6, GUAIAZULENE, LEAD ACETATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	products that may be aerosolized (airborne)	COCAMIDE MEA, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE, POLYOXYMETHYLENE UREA
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on infant skin	products for use on infant skin	SODIUM BORATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	CETEARETH-20, PEG-20 CORN GLYCERIDES, PEG-7 GLYCERYL COCOATE, TRICETEARETH 4 PHOSPHATE, DIMETHICONE PEG-7 ISOSTEARATE, PEG-100 STEARATE, PEG-60, PEG-60 HYDROGENATED CASTOR OIL
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Safe for brief discontinuous use followed by thorough rinsing	products that are intended to be left on the skin	AMMONIUM PERSULFATE, HYDROQUINONE, POTASSIUM PERSULFATE, SODIUM PERSULFATE, ETHANOLAMINE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		RESORCINOL, CETYLPYRIDINIUM CHLORIDE, DMDM HYDANTOIN, IODOPROPYNYL BUTYLCARBAMATE, ZINC PYRITHIONE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		BENZETHONIUM CHLORIDE, CHOLECALCIFEROL, CITRIC ACID, HYDROQUINONE, METHYLISOTHIAZOLINONE, P-PHENYLENEDIAMINE, RETINYL PALMITATE, SALICYLIC ACID, SODIUM BORATE, TRICLOSAN, VEGETABLE FATTY ACID, VITAMIN A, VITAMIN D2
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics	products for use on the lips	HYDROGEN PEROXIDE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		1-NAPHTHOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORORESORCINOL, AMMONIUM PERSULFATE, DIMETHICONE, EXT D&C VIOLET 2, GLYCERYL MONOSTEARATE, M-AMINOPHENOL, M-PHENYLENEDIAMINE, N-PHENYL-P-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, POTASSIUM PERSULFATE, SODIUM PERSULFATE, OCTOXYNOL-40, PHENYLENEDIAMINE, M-
Determined safe for use in cosmetics, subject to concentration or use limitations - any		1-NAPHTHOL, 2-AMINO-4-HYDROXYETHYLAMINOANISOLE SULFATE, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORORESORCINOL, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, M-AMINOPHENOL, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, O-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, PHENYL METHYL PYRAZOLONE, RESORCINOL, 1,2,4-TRIHYDROXYBENZENE, 2,4-DIAMINOPHENOXYETHANOL SULFATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Determined safe for use when formulated to avoid irritation, in assessment by industry safety panel (Cosmetic Ingredient Review, CIR)	products for use on damaged skin or infants	PENTASODIUM PENTETATE
Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel		OCTOXYNOL-9, 4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ACETAMIDE MEA, ALOE BARBADENSIS (ALOE VERA), ALOE BARBADENSIS (ALOE VERA) GEL, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, AMINOMETHYL PROPANOL, AMMONIUM PERSULFATE, BENZETHONIUM CHLORIDE, CETEARETH-20, COCAMIDE MEA, DIAZOLIDINYL UREA, ETHANOLAMINE, EXT D&C VIOLET 2, HYDROGENATED LECITHIN, HYDROQUINONE, IODOPROPYNYL BUTYLCARBAMATE, LAURAMIDE DEA, M-PHENYLENEDIAMINE, METHYLISOTHIAZOLINONE, N-PHENYL-P-PHENYLENEDIAMINE, PEG-20 CORN GLYCERIDES, PEG-7 GLYCERYL COCOATE, POLYACRYLAMIDE, POLYOXYMETHYLENE UREA, POTASSIUM PERSULFATE, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM BORATE, SODIUM LAURYL SULFATE, SODIUM METASILICATE, SODIUM PERSULFATE, SODIUM POLYACRYLATE, SODIUM SULFATE, TRICETEARETH 4 PHOSPHATE, TRIETHANOLAMINE, DIMETHICONE PEG-7 ISOSTEARATE, OCTOXYNOL-40, PEG-100 STEARATE, PEG-60, PEG-60 HYDROGENATED CASTOR OIL, PHENYLENEDIAMINE, M-

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL, HYDROQUINONE, LEAD ACETATE, P-PHENYLENEDIAMINE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		BENZETHONIUM CHLORIDE, CITRIC ACID, FD&C YELLOW 5, HYDROCORTISONE ACETATE, HYDROGEN PEROXIDE, SODIUM SACCHARIN, STEARIC ACID, 1,2,4-TRIHYDROXYBENZENE
One or more animal studies show brain and nervous system effects at low doses		4-CHLORORESORCINOL, BHT, DISODIUM EDTA, LAURETH-23, SALICYLIC ACID, SODIUM CITRATE, SODIUM SULFITE, TETRASODIUM PYROPHOSPHATE, VITAMIN D2, ZEA MAYS (CORN) OIL
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at moderate doses		AMINOMETHYL PROPANOL, AMMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BISABOLOL, CETEARETH-20, CHOLECALCIFEROL, DENATONIUM BENZOATE, DIOCTYL SODIUM SULFOSUCCINATE, DISODIUM PHOSPHATE, EDTA, ETHANOLAMINE, ETIDRONIC ACID, GUAIAZULENE, M-AMINOPHENOL, M-PHENYLENEDIAMINE, MAGNESIUM SULFATE, MENTHOL, METHYLPARABEN, N-PHENYL-P-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL, RESORCINOL, SODIUM LAURYL SULFATE, STEARALKONIUM CHLORIDE, ZINC PYRITHIONE, PHENYLENEDIAMINE, M-, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
One or more animal studies show brain and nervous system effects at high doses		1-NAPHTHOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ACETIC ACID, BENZOCAINE, BENZOPHENONE-1, CHOLESTEROL, DIAZOLIDINYL UREA, DIPROPYLENE GLYCOL, ETHOXYDIGLYCOL, FD&C BLUE 1, FD&C YELLOW 6, GLYCERIN, HYDROXYETHYLCELLULOSE, PHENYL METHYL PYRAZOLONE, POLYACRYLAMIDE, POLYSORBATE-80, PROPYLENE GLYCOL, RETINYL PALMITATE, SODIUM BICARBONATE, SODIUM BORATE, VITAMIN A, ZINC OXIDE (NON-NANO), POLOXAMER 234, POLOXAMER 334, POLOXAMER 407
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHANOL, ISOPROPYL ACETATE, PROPANE, SD ALCOHOL 40, SD ALCOHOL 40B
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more studies show endocrine disruption at very low doses		TRICLOSAN
One or more studies show endocrine system disruption at low doses		BHT, ETIDRONIC ACID, HYDROCORTISONE ACETATE
Limited evidence of any disruption		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, PROPYLPARABEN, OCTOXYNOL-9, RESORCINOL, OCTOXYNOL-40
One or more animal studies show endocrine disruption at moderate doses		BENZOPHENONE-2, CYCLOPENTASILOXANE
One or more animal studies show endocrine disruption at moderate doses		1-NAPHTHOL, BENZETHONIUM CHLORIDE, BENZOPHENONE-1, DIOCTYL SODIUM SULFOSUCCINATE
One or more studies show weak endocrine disruption		BUTYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show endocrine system disruption at high doses		4-AMINO-2-HYDROXYTOLUENE, ALCOHOL DENATURED, AMINOMETHYL PROPANOL, AMMONIUM CHLORIDE, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BISABOLOL, CHOLESTEROL, D&C GREEN 5, DIAZOLIDINYL UREA, DISODIUM EDTA, ECHINACEA PURPUREA (PURPLE CONEFLOWER) EXTRACT, ETHANOL, ETHANOLAMINE, ETHOXYDIGLYCOL, FD&C YELLOW 6, GLYCERIN, HYDROGEN PEROXIDE, HYDROQUINONE, HYDROXYPROPYL METHYLCELLULOSE, LAURETH-23, MAGNESIUM STEARATE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, N-PHENYL-P-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE, POLYSORBATE-20, PROPYLENE GLYCOL, PVP, SACCHARIN, SODIUM BICARBONATE, SODIUM BORATE, SODIUM LAURYL SULFATE, SODIUM SACCHARIN, STEARIC ACID, TRIETHANOLAMINE, ZINC PYRITHIONE, PEG-100 STEARATE, PEG-60, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
Associated with endocrine disruption		SULISOBENZONE (BENZOPHENONE-4)

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		AMMONIUM PERSULFATE, BENZOCAINE, BHT, DIAZOLIDINYL UREA, DMDM HYDANTOIN, FRAGRANCE, HYDROQUINONE, METHYLISOTHIAZOLINONE, N-PHENYL-P-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, RESORCINOL, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Human any toxicant - strong evidence		IODOPROPYNYL BUTYLCARBAMATE, ISOBUTANE, PROPANE
Human immune and respiratory toxicant - strong evidence		ACETIC ACID, ETHANOLAMINE, ZINC OXIDE (NON-NANO), SULFURIC ACID
Human immune system toxicant - strong evidence	products that may be aerosolized (airborne)	SILICA, POLOXAMER 234, POLOXAMER 334, POLOXAMER 407
Human skin toxicant - strong evidence		1-NAPHTHOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORORESORCINOL, ACETYLATED LANOLIN ALCOHOL, BENZOPHENONE-1, BENZOPHENONE-2, BUTYLPARABEN, EXT D&C VIOLET 2, LANOLIN ALCOHOL, M-AMINOPHENOL, M-PHENYLENEDIAMINE, METHYLPARABEN, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, OCTOXYNOL-9, PHENYL METHYL PYRAZOLONE, POTASSIUM PERSULFATE, PROPYLPARABEN, SODIUM METASILICATE, SODIUM PERSULFATE, SULISOBENZONE (BENZOPHENONE-4), TOCOPHERYL ACETATE, OCTOXYNOL-40, PHENYLENEDIAMINE, M-
Limited evidence of immune system toxicity		LEAD ACETATE, ZINC PYRITHIONE, PROPYLENE GLYCOL
Human immune system toxicant - moderate evidence		SODIUM SULFITE, VEGETABLE FATTY ACID
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE), HYDROLYZED WHEAT PROTEIN
Limited evidence of any toxicity		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL
One or more animal studies show gastrointestinal effects at moderate doses		MICA

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife and humans	products that may be aerosolized (airborne)	SILICA
Persistent, bioaccumulative in wildlife and humans		LEAD ACETATE, MICA
Persistent, bioaccumulative in wildlife		CHOLESTEROL, CYCLOMETHICONE, CYCLOPENTASILOXANE, SALICYLIC ACID, TRICLOSAN, ZINC OXIDE (NON-NANO), ZINC PYRITHIONE
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Not suspected to be persistent		1-DODECANOL, 1-NAPHTHOL, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, 4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, 4-CHLORORESORCINOL, ACETAMIDE MEA, ACETYLATED LANOLIN ALCOHOL, AMINOMETHYL PROPANOL, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BENZOCAINE, BENZOPHENONE-1, BENZOPHENONE-2, BISABOLOL, BUTYLPARABEN, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CETEARETH-20, CETEARYL ALCOHOL, CETYL ACETATE, CETYL ALCOHOL, CETYLPYRIDINIUM CHLORIDE, CHOLECALCIFEROL, CITRIC ACID, COCAMIDE MEA, D&C VIOLET 2, D&C YELLOW 10, DENATONIUM BENZOATE, DIAZOLIDINYL UREA, DIMETHICONE, DIPROPYLENE GLYCOL, DISODIUM COCOAMPHODIACETATE, DISODIUM EDTA, DMDM HYDANTOIN, ERYTHORBIC ACID, ETIDRONIC ACID, FD&C RED 4, FD&C YELLOW 6, GLUCONOLACTONE, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, GUAIAZULENE, HYDROCORTISONE ACETATE, HYDROGENATED CASTOR OIL, HYDROQUINONE, IODOPROPYNYL BUTYLCARBAMATE, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, LAURETH-23, LINOLEIC ACID, M-PHENYLENEDIAMINE, MAGNESIUM STEARATE, MENTHOL, METHYLISOTHIAZOLINONE, METHYLPARABEN, MYRISTYL PROPIONATE, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, N-PHENYL-P-PHENYLENEDIAMINE, O-AMINOPHENOL, OCTOXYNOL-9, OLEYL ALCOHOL, P-AMINOPHENOL, P-PHENYLENEDIAMINE, PANTHENOL, PETROLATUM, PHENYL METHYL PYRAZOLONE, POTASSIUM STEARATE, PROPYLPARABEN, RETINYL PALMITATE, SACCHARIN, SODIUM CITRATE, SODIUM COCOATE, SODIUM GLUCONATE, SODIUM LAURYL SULFATE, SODIUM SACCHARIN, SODIUM TALLOWATE, SORBITAN STEARATE, STEARALKONIUM CHLORIDE, STEARIC ACID, STEARYL ALCOHOL, SULFATED CASTOR OIL, SULISOBENZONE (BENZOPHENONE-4), TETRASODIUM ETIDRONATE, TOLNAFTATE, TRISODIUM EDTA, VITAMIN D2, WHITE PETROLATUM, C11-15 PARETH-3, C11-15 PARETH-9, DIMETHYL OXAZOLIDINE, OCTOXYNOL-40, PEG-100 STEARATE, STEARETH-21, TRISODIUM HEDTA, PHENYLENEDIAMINE, M-, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
Not suspected to be bioaccumulative		BENZETHONIUM CHLORIDE, CALCIUM HYDROXIDE, CARBOMER, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, D&C GREEN 5, D&C ORANGE 4, DISODIUM PHOSPHATE, EXT D&C VIOLET 2, FD&C BLUE 1, FD&C GREEN 3, FD&C YELLOW 5, ISOBUTANE, ISOPROPYL ACETATE, M-AMINOPHENOL, MAGNESIUM SULFATE, PENTASODIUM PENTETATE, PHENYL TRIMETHICONE, POLYOXYMETHYLENE UREA, POLYQUATERNIUM-11, POLYQUATERNIUM-5, POTASSIUM PERSULFATE, VP/ EICOSENE COPOLYMER, SODIUM BICARBONATE, SODIUM METASILICATE, SODIUM PERSULFATE, SODIUM PHOSPHATE, SODIUM SULFATE, SODIUM SULFITE, SULFUR, TETRASODIUM PYROPHOSPHATE, TOCOPHEROL, TOCOPHERYL ACETATE, TRICALCIUM PHOSPHATE, VEGETABLE FATTY ACID, VP/ VA COPOLYMER, WATER, ZEA MAYS (CORN) OIL, POLOXAMER 234, POLOXAMER 334, POLOXAMER 407
Persistent or bioaccumulative and moderate to high toxicity concern in humans		ACETIC ACID, AMMONIUM CHLORIDE, AMMONIUM PERSULFATE, BHT, DIOCTYL SODIUM SULFOSUCCINATE, ETHANOLAMINE, ETHOXYDIGLYCOL, HYDROGEN PEROXIDE, LAURAMIDE DEA, MINERAL OIL, PARAFFIN, POLYACRYLAMIDE, PROPYLENE GLYCOL, RESORCINOL, SODIUM LAURETH SULFATE, TETRASODIUM EDTA

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Known human lung and skin toxicant	products that may be aerosolized (airborne); products for use on skin	1-NAPHTHOL
Known human respiratory toxicant		HYDROQUINONE, LEAD ACETATE, P-PHENYLENEDIAMINE
Known human respiratory toxicant	products that may be aerosolized (airborne)	SILICA
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		AMMONIUM PERSULFATE, ETHANOLAMINE, O-AMINOPHENOL, P-AMINOPHENOL, SODIUM SULFITE, TRIETHANOLAMINE, VEGETABLE FATTY ACID, MICA
One or more animal studies show broad systemic effects at very low doses		AMMONIUM CHLORIDE, MAGNESIUM SULFATE, SULFUR, VITAMIN D2, PEG-60, ACETIC ACID, GLYCERIN, FD&C YELLOW 5,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	BENZETHONIUM CHLORIDE, CITRIC ACID, STEARIC ACID, TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ACETAMIDE MEA, ALCOHOL DENATURED, CALCIUM HYDROXIDE, DIOCTYL SODIUM SULFOSUCCINATE, DISODIUM COCOAMPHODIACETATE, ETHANOL, HYDROGEN PEROXIDE, ISOPROPYL ALCOHOL, LAURETH-23, M-PHENYLENEDIAMINE, MENTHOL, POLYOXYMETHYLENE UREA, RESORCINOL, SALICYLIC ACID, SODIUM LAURETH SULFATE, STEARALKONIUM CHLORIDE, C11-15 PARETH-3, C11-15 PARETH-9, SULFURIC ACID, PHENYLENEDIAMINE, M-
One or more animal studies show blood effects at low doses		BENZOCAINE, ETIDRONIC ACID, BENZOPHENONE-1, CHOLECALCIFEROL, DISODIUM EDTA, EDTA, HYDROCORTISONE ACETATE, ISOPROPYL PALMITATE, SODIUM BORATE, SODIUM LAURYL SULFATE, SODIUM PERSULFATE, TOLNAFTATE, TRICLOSAN, ZINC PYRITHIONE, 1,2,4-TRIHYDROXYBENZENE, OCTOXYNOL-40, POLOXAMER 234, POLOXAMER 334, POLOXAMER 407, TETRASODIUM PYROPHOSPHATE,
One or more animal studies show respiratory effects at low doses	products that may be aerosolized (airborne)	BHT, SODIUM CITRATE, HAIR KERATIN AMINO ACIDS
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	BENZOPHENONE-2, CETEARETH-20, ETHOXYDIGLYCOL, LAURAMIDE DEA, M-AMINOPHENOL, MINERAL OIL, N-PHENYL-P-PHENYLENEDIAMINE, OCTOXYNOL-9, SODIUM POLYACRYLATE, SULISOBENZONE (BENZOPHENONE-4)
Classified as toxic or harmful	products for use around the mouth; products for use on the lips	POTASSIUM PERSULFATE
Limited evidence of any toxicity	products that may be aerosolized (airborne)	ZINC OXIDE (NON-NANO)
Limited evidence of gastrointestinal or liver toxicity		IODOPROPYNYL BUTYLCARBAMATE, SD ALCOHOL 40, SD ALCOHOL 40B, BUTYLPARABEN, PEG-20 CORN GLYCERIDES, PEG-7 GLYCERYL COCOATE, PROPYLPARABEN, DIMETHICONE PEG-7 ISOSTEARATE, PEG-100 STEARATE, PEG-60 HYDROGENATED CASTOR OIL, RETINYL PALMITATE, VITAMIN A
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)		C13-14 ISOPARAFFIN
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		1-DODECANOL, 2-METHYL-5-HYDROXYETHYLAMINOPHENOL, 2-METHYLRESORCINOL, 4-AMINO-2-HYDROXYTOLUENE, ALOE BARBADENSIS (ALOE VERA) GEL, CETYLPYRIDINIUM CHLORIDE, DISODIUM PHOSPHATE, DMDM HYDANTOIN, GLYCERYL MONOSTEARATE, GUAIAZULENE, LINOLEIC ACID, N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE, PVP, SODIUM PHOSPHATE, TOCOPHERYL ACETATE, DIMETHYL OXAZOLIDINE, STEARETH-21, SODIUM BICARBONATE,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1, PROPANE, SACCHARIN, SODIUM SULFATE
One or more animal studies show gastrointestinal effects at moderate doses (low dose studies may be unavailable for this ingredient)		SODIUM METASILICATE, TETRASODIUM ETIDRONATE, TRISODIUM EDTA, POLYACRYLAMIDE, ZEA MAYS (CORN) OIL,
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	AMINOMETHYL PROPANOL, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BISABOLOL, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	4-CHLORORESORCINOL, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CETYL ALCOHOL, CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C GREEN 5, DIPROPYLENE GLYCOL, OLEYL ALCOHOL, PARAFFIN, PHENYL METHYL PYRAZOLONE, POLYSORBATE-80, STEARYL ALCOHOL, TRITICUM VULGARE (WHEAT) GERM OIL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		D&C YELLOW 10, DIAZOLIDINYL UREA, ERYTHORBIC ACID, HYDROXYPROPYL METHYLCELLULOSE, ISOPROPYL MYRISTATE, ISOPROPYL STEARATE, PANTHENOL, SODIUM GLUCONATE, SODIUM SACCHARIN, ZEA MAYS (CORN) STARCH, HYDROXYETHYLCELLULOSE, FD&C YELLOW 6, POLYSORBATE-20, D&C ORANGE 4, MAGNESIUM STEARATE,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		VP/ VA COPOLYMER,
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CHOLESTEROL, D&C VIOLET 2, ISOPROPYL ACETATE
Classified as expected to be toxic or harmful		DIMETHICONE, ISOBUTANE, MICROCRYSTALLINE WAX (CERA MICROCRISTALLINA), PETROLATUM, POLYQUATERNIUM-5, WHITE PETROLATUM
Classified as not expected to be potentially toxic or harmful		4-CHLORO-5 METHYL-2-(1-METHYLETHYL)-PHENOL, ACETYLATED LANOLIN ALCOHOL, ALOE BARBADENSIS (ALOE VERA), BEESWAX, BUTYROSPERMUM PARKII (SHEA BUTTER), CAPRYLIC/ CAPRIC TRIGLYCERIDE, CARAMEL, CARBOMER, CETEARYL ALCOHOL, CETYL ACETATE, COCAMIDE MEA, DENATONIUM BENZOATE, EXT D&C VIOLET 2, FD&C GREEN 3, FD&C RED 4, GLUCONOLACTONE, GLYCERYL STEARATE SE, HYDROGENATED CASTOR OIL, HYDROLYZED ELASTIN, LANOLIN ALCOHOL, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, METHYLISOTHIAZOLINONE, MYRISTYL PROPIONATE, PENTASODIUM PENTETATE, PHENYL TRIMETHICONE, POLYQUATERNIUM-10, POLYQUATERNIUM-11, POTASSIUM STEARATE, VP/ EICOSENE COPOLYMER, SODIUM COCOATE, SODIUM TALLOWATE, SORBITAN STEARATE, SULFATED CASTOR OIL, TOCOPHEROL, TRICALCIUM PHOSPHATE, WATER, TRISODIUM HEDTA

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE, UNSPECIFIED FLAVOR, FLAVOR
Prohibited for use in food		SODIUM BORATE
Occupational hazards related to handling		ACETIC ACID, ALCOHOL DENATURED, AMMONIUM PERSULFATE, ETHANOL, ETHANOLAMINE, HYDROGEN PEROXIDE, ISOBUTANE, ISOPROPYL ACETATE, ISOPROPYL ALCOHOL, POTASSIUM PERSULFATE, PROPANE, SD ALCOHOL 40, SD ALCOHOL 40B, SODIUM METASILICATE, SULFURIC ACID
Occupational hazards related to handling	products for use around the mouth; products for use on the lips; products for use on skin	CHOLECALCIFEROL

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ALCOHOL DENATURED, ANTHEMIS NOBILIS (CHAMOMILE), ETHANOL, ISOBUTANE, MENTHOL, OCTOXYNOL-9, PANTHENOL, POLYQUATERNIUM-5, PROPANE, SACCHARIN, SALICYLIC ACID, SD ALCOHOL 40, SD ALCOHOL 40B, SODIUM BORATE, SODIUM POLYACRYLATE, CITRUS GRANDIS (GRAPEFRUIT) FRUIT EXTRACT, OCTOXYNOL-40
Designated as safe for general or specific, limited use in food	products that may be aerosolized (airborne)	SILICA
Designated as safe for general or specific, limited use in food		1-DODECANOL, ACETIC ACID, ALCOHOL DENATURED, ALOE BARBADENSIS (ALOE VERA), ALOE BARBADENSIS (ALOE VERA) GEL, AMMONIUM CHLORIDE, AMMONIUM PERSULFATE, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BEESWAX, BHT, BUTYLPARABEN, CALCIUM HYDROXIDE, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CARAMEL, CETYL ALCOHOL, CETYLPYRIDINIUM CHLORIDE, CHOLECALCIFEROL, CITRIC ACID, DIMETHICONE, DIOCTYL SODIUM SULFOSUCCINATE, DISODIUM EDTA, DISODIUM PHOSPHATE, ERYTHORBIC ACID, ETHANOL, ETHANOLAMINE, ETHOXYDIGLYCOL, ETIDRONIC ACID, FD&C BLUE 1, FD&C GREEN 3, FD&C YELLOW 5, FD&C YELLOW 6, GLUCONOLACTONE, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCERYL STEARATE SE, HYDROGEN PEROXIDE, HYDROXYPROPYL METHYLCELLULOSE, ISOBUTANE, ISOPROPYL ACETATE, ISOPROPYL ALCOHOL, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, LAURAMIDE DEA, LAURETH-23, LINOLEIC ACID, MAGNESIUM STEARATE, MAGNESIUM SULFATE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, MENTHOL, METHYLPARABEN, MINERAL OIL, PARAFFIN, PEG-20 CORN GLYCERIDES, PEG-7 GLYCERYL COCOATE, PETROLATUM, POLYACRYLAMIDE, POLYSORBATE-20, POLYSORBATE-80, POTASSIUM PERSULFATE, POTASSIUM STEARATE, PROPANE, PROPYLENE GLYCOL, PROPYLPARABEN, PVP, RESORCINOL, RETINYL PALMITATE, SACCHARIN, SALICYLIC ACID, SODIUM BICARBONATE, SODIUM CITRATE, SODIUM GLUCONATE, SODIUM LAURYL SULFATE, SODIUM METASILICATE, SODIUM PHOSPHATE, SODIUM POLYACRYLATE, SODIUM SACCHARIN, SODIUM SULFATE, SODIUM SULFITE, SORBITAN STEARATE, STEARIC ACID, STEARYL ALCOHOL, TETRASODIUM EDTA, TETRASODIUM PYROPHOSPHATE, TITANIUM DIOXIDE (NON-NANO), TOCOPHEROL, TOCOPHERYL ACETATE, TRICALCIUM PHOSPHATE, TRIETHANOLAMINE, VITAMIN A, VITAMIN D2, WHITE PETROLATUM, ZEA MAYS (CORN) STARCH, ZINC OXIDE (NON-NANO), DIMETHICONE PEG-7 ISOSTEARATE, PEG-100 STEARATE, PEG-60, PEG-60 HYDROGENATED CASTOR OIL, POLOXAMER 234, POLOXAMER 334, POLOXAMER 407, SULFURIC ACID

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		1-NAPHTHOL, AMINOMETHYL PROPANOL, AMMONIUM CHLORIDE, AMMONIUM PERSULFATE, EDTA, ISOPROPYL ACETATE, ISOPROPYL ALCOHOL, M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE, POTASSIUM PERSULFATE, RESORCINOL, SODIUM METASILICATE, SULFUR, TRICLOSAN, PHENYLENEDIAMINE, M-, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	DIPROPYLENE GLYCOL, DMDM HYDANTOIN, GLYCERYL MONOSTEARATE, ISOBUTANE, ISOPROPYL MYRISTATE, ISOPROPYL STEARATE, LAURETH-23, LAURETH-4, OCTOXYNOL-9, OLEYL ALCOHOL, PROPANE, SODIUM LAURETH SULFATE, SODIUM LAURYL SULFATE, STEARYL ALCOHOL, SULISOBENZONE (BENZOPHENONE-4), OCTOXYNOL-40
Human skin irritant - moderate evidence		ETHANOLAMINE, HYDROGEN PEROXIDE
One or more animal studies show skin irritation at very low doses		1-DODECANOL, ACETIC ACID, CETYL ALCOHOL, DISODIUM COCOAMPHODIACETATE, HYDROQUINONE, LAURAMIDE DEA, POLYOXYMETHYLENE UREA, TRIETHANOLAMINE, 1,2,4-TRIHYDROXYBENZENE, PEG-100 STEARATE
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show skin irritation at low doses		ALCOHOL DENATURED, BHT, CETEARETH-20, CETYLPYRIDINIUM CHLORIDE, DIOCTYL SODIUM SULFOSUCCINATE, ETHANOL, ISOPROPYL PALMITATE, LINOLEIC ACID, METHYLPARABEN, STEARIC ACID, TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		4-CHLORORESORCINOL, ACETAMIDE MEA, ANTHEMIS NOBILIS (CHAMOMILE), ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT, BENZETHONIUM CHLORIDE, BENZOCAINE, BISABOLOL, BUTYLPARABEN, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CETYL ACETATE, CITRIC ACID, CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C GREEN 5, DISODIUM PHOSPHATE, ETHOXYDIGLYCOL, GLYCERIN, M-AMINOPHENOL, MENTHOL, MINERAL OIL, N-PHENYL-P-PHENYLENEDIAMINE, P-AMINOPHENOL, PARAFFIN, POLYSORBATE-20, SALICYLIC ACID, SODIUM BICARBONATE, SORBITAN STEARATE, STEARALKONIUM CHLORIDE, TRITICUM VULGARE (WHEAT) GERM OIL, VITAMIN A, ZEA MAYS (CORN) OIL, ZEA MAYS (CORN) STARCH, ZINC OXIDE (NON-NANO), C11-15 PARETH-3, C11-15 PARETH-9, PEG-60, ANTHEMIS NOBILIS (CHAMOMILE) EXTRACT
One or more animal studies show skin irritation at high doses		4-AMINO-2-HYDROXYTOLUENE, CHOLESTEROL, IODOPROPYNYL BUTYLCARBAMATE, SODIUM SULFITE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to very low doses		CHOLECALCIFEROL, VITAMIN D2
Allowed workplace exposures restricted to very low doses		AMMONIUM PERSULFATE, LEAD ACETATE, M-PHENYLENEDIAMINE, P-PHENYLENEDIAMINE, POTASSIUM PERSULFATE, SODIUM PERSULFATE, SULFURIC ACID, PHENYLENEDIAMINE, M-
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), 1-NAPHTHOL, AMMONIUM CHLORIDE, ETHANOLAMINE, HYDROGEN PEROXIDE, M-AMINOPHENOL, O-AMINOPHENOL, P-AMINOPHENOL, RESORCINOL, TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		BHT, HYDROQUINONE, MICA, PARAFFIN, SODIUM BORATE, SODIUM STANNATE, ZINC OXIDE (NON-NANO)
Allowed workplace exposures restricted to moderate doses		ACETIC ACID, CALCIUM HYDROXIDE, GLYCERIN, MAGNESIUM STEARATE, MINERAL OIL, POTASSIUM STEARATE, TETRASODIUM PYROPHOSPHATE, TRIETHANOLAMINE, VEGETABLE FATTY ACID, ZEA MAYS (CORN) STARCH,
Allowed workplace exposures restricted to moderate doses	products that may be aerosolized (airborne)	ISOPROPYL ACETATE, ISOPROPYL ALCOHOL
Allowed workplace exposures restricted to high doses		ETHANOL, ISOBUTANE, PROPANE,
Allowed workplace exposures restricted to high doses		ALCOHOL DENATURED

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		HYDROCORTISONE ACETATE, SILICA,
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		BHT
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		ETIDRONIC ACID, LAURAMIDE DEA, LAURETH-23, P-AMINOPHENOL, SODIUM LAURYL SULFATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALCOHOL DENATURED, BENZOPHENONE-2, CHOLESTEROL, CITRIC ACID, CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C GREEN 5, D&C ORANGE 4, DIOCTYL SODIUM SULFOSUCCINATE, ETHANOL, GLYCERIN, HYDROGEN PEROXIDE, MAGNESIUM SULFATE, N-PHENYL-P-PHENYLENEDIAMINE, POLYACRYLAMIDE, PROPYLENE GLYCOL, SODIUM BICARBONATE, ZEA MAYS (CORN) OIL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		RETINYL PALMITATE, VITAMIN A, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN