Alva-Amco Pharmacal Cos., Inc. || Skin Deep: Cosmetic Safety Reviews

Manufacturer: Alva-Amco Pharmacal Cos., Inc.

Brands: Psoriasin, FUNGICURE, Herpetrol, Prosacea, Backaid, Alva-Amco Pharmacal Company

COMPANY SUMMARY

product score range	2	to	8
product count	16		(browse)
ingredient count	33
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this company -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this company:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this company: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 16 products by Alva-Amco Pharmacal Cos., Inc.

Product type(s) by this company in Skin Deep: anti-fungal treatment (4), anti-itch/rash cream (5), athlete's foot treatment (4), body wash/cleanser (1), dandruff/scalp treatment (2), eczema/damaged skin treatment (2), facial moisturizer/treatment (1), moisturizer (2), oral pain relief (1), redness/rosacea treatment (4), shampoo (1)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	2 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
COAL TAR	10	57%	4 products	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (BENZO[A]PYRENE)
FRAGRANCE	8	100%	4 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
POLYETHYLENE GLYCOL	8	69%	2 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
SALICYLIC ACID	7	66%	1 products	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
BENZALKONIUM CHLORIDE	7	62%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DIAZOLIDINYL UREA	6	59%	1 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHANOL	5	74%	4 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
ETHYLENE GLYCOL	5	74%	1 products	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHOXYETHANOL, METHOXYETHANOL), Occupational hazards
PROPYLPARABEN	5	71%	1 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
ACETIC ACID	2	74%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
ISOPROPYL ALCOHOL	4	72%	6 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
TOLNAFTATE	4	71%	1 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive)
ACRYLATES COPOLYMER	3	75%	1 products	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
PETROLATUM	2	94%	3 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
PANTHENOL	2	88%	1 products	Multiple, additive exposure sources
TOCOPHEROL	2	87%	5 products	Contamination concerns (HYDROQUINONE)
TETRASODIUM EDTA	2	81%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
POLYSORBATE-80	2	80%	4 products	Developmental/reproductive toxicity
SODIUM C14-16 OLEFIN SULFONATE	2	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (GAMMA SULTONE)
LAURAMIDOPROPYL BETAINE	0	89%	1 products	none identified
HYDROXYPROPYL METHYLCELLULOSE	1	88%	3 products	none identified
HYDROXYPROPYLCELLULOSE	1	88%	2 products	none identified
LYSINE HYDROCHLORIDE	1	87%	1 products	none identified
SULFUR	1	86%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
UNDECYLENIC ACID	1	86%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
LACTOSE	1	79%	1 products	none identified
PROPYLENE	1	79%	1 products	Organ system toxicity (non-reproductive), Occupational hazards
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	6 products	none identified
PHOSPHOLIPID EFA	0	100%	1 products	none identified
SODIUM CHLORIDE	0	0%	1 products	innocuous
WATER	0	0%	7 products	innocuous

* Product counts only include current formulations sold by this company. The company may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this company that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human carcinogen		COAL TAR
Cancer - not classifiable/not likely to be human carcinogen		ISOPROPYL ALCOHOL, PROPYLENE, TRIETHANOLAMINE
Cancer - limited evidence		ETHANOL
Cancer - not classifiable/not likely to be human carcinogen		SALICYLIC ACID
One or more in vitro tests on mammalian cells show positive mutation results		ACETIC ACID, BENZALKONIUM CHLORIDE, DIAZOLIDINYL UREA, ETHYLENE GLYCOL, METHYLPARABEN, POLYETHYLENE GLYCOL, POLYSORBATE-80, PROPYLPARABEN, SODIUM CHLORIDE, TOCOPHEROL
One or more animal studies show tumor formation at high doses		LACTOSE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		ETHANOL
One or more animal studies show reproductive effects at very low doses		POLYETHYLENE GLYCOL, POLYSORBATE-80
One or more animal studies show any effects at low doses		PROPYLPARABEN
Limited evidence of developmental toxicity		ETHYLENE GLYCOL, ISOPROPYL ALCOHOL
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL
One or more animal studies show reproductive effects at moderate doses		SALICYLIC ACID, TOLNAFTATE
One or more animal studies show reproductive effects at high doses		ACETIC ACID, LACTOSE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN, COAL TAR, TOLNAFTATE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	POLYETHYLENE GLYCOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		BENZALKONIUM CHLORIDE, SALICYLIC ACID
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		COAL TAR
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		ACRYLATES COPOLYMER, ALOE BARBADENSIS (ALOE VERA) GEL, BENZALKONIUM CHLORIDE, DIAZOLIDINYL UREA, POLYETHYLENE GLYCOL, SALICYLIC ACID, SODIUM C14-16 OLEFIN SULFONATE, TRIETHANOLAMINE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ISOPROPYL ALCOHOL
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at low doses		SALICYLIC ACID
One or more animal studies show brain and nervous system effects at moderate doses		ETHYLENE GLYCOL, METHYLPARABEN
One or more animal studies show brain and nervous system effects at high doses		ACETIC ACID, DIAZOLIDINYL UREA, LYSINE HYDROCHLORIDE, POLYSORBATE-80, UNDECYLENIC ACID
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		ETHANOL

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		METHYLPARABEN, PROPYLPARABEN
One or more animal studies show endocrine system disruption at high doses		DIAZOLIDINYL UREA, LACTOSE, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		BENZALKONIUM CHLORIDE, DIAZOLIDINYL UREA, FRAGRANCE, TRIETHANOLAMINE
Human immune and respiratory toxicant - strong evidence		ACETIC ACID
Human skin toxicant - strong evidence		COAL TAR, METHYLPARABEN, PROPYLPARABEN

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		SALICYLIC ACID
Not suspected to be persistent		BENZALKONIUM CHLORIDE, DIAZOLIDINYL UREA, ETHYLENE GLYCOL, LACTOSE, LAURAMIDOPROPYL BETAINE, LYSINE HYDROCHLORIDE, METHYLPARABEN, PANTHENOL, PROPYLPARABEN, TOLNAFTATE
Not suspected to be bioaccumulative		SODIUM CHLORIDE, SULFUR, TOCOPHEROL, WATER
Not suspected to be bioaccumulative		COAL TAR, ETHANOL, ISOPROPYL ALCOHOL, PETROLATUM, POLYETHYLENE GLYCOL, TRIETHANOLAMINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN, COAL TAR, ETHYLENE GLYCOL
Limited evidence of eye toxicity	products for use around the eyes	TETRASODIUM EDTA
Possible human immune system toxicant		BENZALKONIUM CHLORIDE, TRIETHANOLAMINE
One or more animal studies show broad systemic effects at very low doses		POLYETHYLENE GLYCOL, SULFUR, ACETIC ACID,
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ETHANOL, ISOPROPYL ALCOHOL, SALICYLIC ACID
One or more animal studies show broad systemic effects at low doses		TOLNAFTATE, UNDECYLENIC ACID,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	SODIUM CHLORIDE
Limited evidence of respiratory toxicity		PROPYLENE, PROPYLPARABEN
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALOE BARBADENSIS (ALOE VERA) GEL, HYDROXYPROPYLCELLULOSE,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	POLYSORBATE-80
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		DIAZOLIDINYL UREA, HYDROXYPROPYL METHYLCELLULOSE, PANTHENOL, LACTOSE,
One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	LYSINE HYDROCHLORIDE
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	LAURAMIDOPROPYL BETAINE
Classified as expected to be toxic or harmful		PETROLATUM, SODIUM C14-16 OLEFIN SULFONATE
Classified as not expected to be potentially toxic or harmful		TOCOPHEROL, WATER

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE
Occupational hazards related to handling		ACETIC ACID, ETHANOL, ISOPROPYL ALCOHOL, PROPYLENE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		ETHANOL, PANTHENOL, SALICYLIC ACID
Designated as safe for general or specific, limited use in food		ACETIC ACID, ALOE BARBADENSIS (ALOE VERA) GEL, ETHANOL, HYDROXYPROPYL METHYLCELLULOSE, HYDROXYPROPYLCELLULOSE, ISOPROPYL ALCOHOL, LACTOSE, METHYLPARABEN, PETROLATUM, POLYETHYLENE GLYCOL, POLYSORBATE-80, PROPYLPARABEN, SALICYLIC ACID, SODIUM CHLORIDE, TETRASODIUM EDTA, TOCOPHEROL, TRIETHANOLAMINE, UNDECYLENIC ACID

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		ISOPROPYL ALCOHOL, SULFUR
One or more animal studies show skin irritation at very low doses		ACETIC ACID, TRIETHANOLAMINE, UNDECYLENIC ACID
One or more animal studies show skin irritation at low doses		BENZALKONIUM CHLORIDE, ETHANOL, METHYLPARABEN, TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		COAL TAR, ETHYLENE GLYCOL, POLYETHYLENE GLYCOL, SALICYLIC ACID, SODIUM CHLORIDE

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		ETHYLENE GLYCOL, TETRASODIUM EDTA
Allowed workplace exposures restricted to moderate doses		ACETIC ACID, TRIETHANOLAMINE,
Allowed workplace exposures restricted to moderate doses	products that may be aerosolized (airborne)	ISOPROPYL ALCOHOL
Allowed workplace exposures restricted to high doses		ETHANOL, PROPYLENE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ETHANOL
Interferes with gene expresion		METHYLPARABEN