Bradley Pharmaceuticals, Inc. || Skin Deep: Cosmetic Safety Reviews

Manufacturer: Bradley Pharmaceuticals, Inc.

Brands: Carmol, Acid Mantle, ENTSOL, Trans-Ver-Sal, Anamantle, Doak, Formula 405, Le Pont, Lubrin, Bradley Pharmaceuticals

COMPANY SUMMARY

product score range	3	to	7
product count	31		(browse)
ingredient count	50
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this company -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this company:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this company: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 31 products by Bradley Pharmaceuticals, Inc.

Product type(s) by this company in Skin Deep: anti-aging (1), facial moisturizer/treatment (2), moisturizer (5), sunscreen: moisturizer (1), wart removal (4)

ingredients

	score	data gap	products *	concerns
METHYLPARABEN	10	63%	2 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
OXYBENZONE (BENZOPHENONE-3)	9	55%	1 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	2 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
POLYETHYLENE GLYCOL	8	69%	2 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	8	65%	1 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
PEG-100 STEARATE	4	69%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
SALICYLIC ACID	7	66%	4 products	Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption
PEG-300	6	76%	4 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 DIOLEATE	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 DISTEARATE	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
QUATERNIUM-15	6	65%	4 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	3 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ALUMINUM SULFATE	5	80%	2 products	Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
IMIDAZOLIDINYL UREA	5	70%	2 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
LACTIC ACID	5	70%	2 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
RETINYL PALMITATE	5	68%	2 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
MAGNESIUM ALUMINUM SILICATE	4	88%	2 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive)
SODIUM LAURETH SULFATE	4	86%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
TOCOPHERYL ACETATE	4	81%	2 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
MINERAL OIL	2	73%	2 products	Organ system toxicity (non-reproductive), Occupational hazards
UREA	4	67%	3 products	Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption
PROPYLENE GLYCOL	4	60%	5 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
DIMETHICONE	2	74%	2 products	Violations, restrictions & warnings
SODIUM LAURYL SULFATE	3	68%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
PETROLATUM	2	94%	4 products	Organ system toxicity (non-reproductive), Contamination concerns (PAHS)
CALCIUM ACETATE	2	85%	2 products	Neurotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
CYCLOMETHICONE	2	83%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
GLYCERIN	2	74%	2 products	Organ system toxicity (non-reproductive), Occupational hazards
HYDROGENATED LECITHIN	2	74%	2 products	Enhanced skin absorption, Contamination concerns (NITROSAMINES)
STEARIC ACID	2	74%	5 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	2 products	none identified
PROPYLENE GLYCOL DIPELARGONATE	0	94%	1 products	none identified
CETEARYL ALCOHOL	0	93%	4 products	none identified
SQUALANE	1	93%	1 products	Irritation (skin, eyes, or lungs)
SODIUM CETEARYL SULFATE	1	91%	2 products	Organ system toxicity (non-reproductive)
GUM KARAYA	1	89%	2 products	none identified
GLYCERYL MONOSTEARATE	1	88%	2 products	none identified
STEARETH-2	1	88%	2 products	none identified
CETYL ALCOHOL	1	87%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL PALMITATE	1	87%	3 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
SYNTHETIC BEESWAX	1	87%	2 products	Irritation (skin, eyes, or lungs)
ISOPROPYL MYRISTATE	1	86%	2 products	Irritation (skin, eyes, or lungs)
POTASSIUM SORBATE	1	85%	2 products	none identified
SODIUM HYALURONATE	1	83%	2 products	none identified
BISABOLOL	1	80%	2 products	Enhanced skin absorption
CITRUS PARADISI (GRAPEFRUIT) OIL	0	100%	2 products	none identified
POTATO DEXTRIN	0	100%	2 products	none identified
XANTHAN GUM	0	94%	5 products	none identified
CARBOMER	0	93%	3 products	none identified
WATER	0	0%	7 products	innocuous

* Product counts only include current formulations sold by this company. The company may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this company that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Cancer - not classifiable/not likely to be human carcinogen		TRIETHANOLAMINE
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		RETINYL PALMITATE
Cancer - not classifiable/not likely to be human carcinogen		LACTIC ACID, SALICYLIC ACID
One or more in vitro tests on mammalian cells show positive mutation results		ALUMINUM SULFATE, CALCIUM ACETATE, GLYCERIN, METHYLPARABEN, POLYETHYLENE GLYCOL, POTASSIUM SORBATE, PROPYLENE GLYCOL, SODIUM LAURYL SULFATE, TOCOPHERYL ACETATE, UREA
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE
One or more in vitro tests non-mammalian cells show positive mutation results		OXYBENZONE (BENZOPHENONE-3), QUATERNIUM-15

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human nervous system toxicant - moderate evidence		ALUMINUM SULFATE, MAGNESIUM ALUMINUM SILICATE
One or more animal studies show reproductive effects at very low doses		POLYETHYLENE GLYCOL
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show reproductive effects at moderate doses		GLYCERIN, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM HYALURONATE,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at high doses		QUATERNIUM-15, SODIUM LAURYL SULFATE, UREA, PEG-100 STEARATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits		LACTIC ACID
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	PEG-300, PEG-8 DIOLEATE, PEG-8 DISTEARATE, POLYETHYLENE GLYCOL, PEG-100 STEARATE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)		OXYBENZONE (BENZOPHENONE-3)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		LACTIC ACID, RETINYL PALMITATE, SALICYLIC ACID, UREA
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		HYDROGENATED LECITHIN, LACTIC ACID, PEG-300, PEG-8 DIOLEATE, PEG-8 DISTEARATE, POLYETHYLENE GLYCOL, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM LAURYL SULFATE, TRIETHANOLAMINE, PEG-100 STEARATE

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ALUMINUM SULFATE, MAGNESIUM ALUMINUM SILICATE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		CALCIUM ACETATE, SALICYLIC ACID
One or more animal studies show brain and nervous system effects at moderate doses		BISABOLOL, METHYLPARABEN, SODIUM HYALURONATE, SODIUM LAURYL SULFATE, UREA
One or more animal studies show brain and nervous system effects at high doses		GLYCERIN, LACTIC ACID, OXYBENZONE (BENZOPHENONE-3), POTASSIUM SORBATE, PROPYLENE GLYCOL, QUATERNIUM-15, RETINYL PALMITATE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show endocrine system disruption at high doses		BISABOLOL, GLYCERIN, QUATERNIUM-15, SODIUM LAURYL SULFATE, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		FRAGRANCE, IMIDAZOLIDINYL UREA, QUATERNIUM-15, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Human skin toxicant - strong evidence		METHYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE, SALICYLIC ACID
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		BISABOLOL, CALCIUM ACETATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CETEARYL ALCOHOL, DIMETHICONE, GLYCERIN, GLYCERYL MONOSTEARATE, IMIDAZOLIDINYL UREA, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, LACTIC ACID, METHYLPARABEN, PEG-8 DIOLEATE, POTASSIUM SORBATE, PROPYLENE GLYCOL DIPELARGONATE, RETINYL PALMITATE, SQUALANE, STEARIC ACID, SYNTHETIC BEESWAX, UREA, PEG-100 STEARATE, STEARETH-2
Not suspected to be persistent		CETYL ALCOHOL, SODIUM LAURYL SULFATE
Not suspected to be bioaccumulative		CARBOMER, MAGNESIUM ALUMINUM SILICATE, TOCOPHERYL ACETATE, WATER
Not suspected to be bioaccumulative		ALUMINUM SULFATE, PETROLATUM, POLYETHYLENE GLYCOL, QUATERNIUM-15, TRIETHANOLAMINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		TRIETHANOLAMINE
One or more animal studies show broad systemic effects at very low doses		POLYETHYLENE GLYCOL, GLYCERIN,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	STEARIC ACID
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	ALUMINUM SULFATE, LACTIC ACID, SALICYLIC ACID, SODIUM LAURETH SULFATE
One or more animal studies show broad systemic effects at low doses		CALCIUM ACETATE, ISOPROPYL PALMITATE, QUATERNIUM-15, SODIUM LAURYL SULFATE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	MINERAL OIL, SODIUM CETEARYL SULFATE
Limited evidence of any toxicity		MAGNESIUM ALUMINUM SILICATE, PEG-300, PEG-8 DIOLEATE, PEG-8 DISTEARATE, PEG-100 STEARATE, RETINYL PALMITATE
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCERYL MONOSTEARATE, POTASSIUM SORBATE, TOCOPHERYL ACETATE, STEARETH-2,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient)	products that may be aerosolized (airborne)	BISABOLOL, UREA
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	CETYL ALCOHOL, CYCLOMETHICONE, SODIUM HYALURONATE, SYNTHETIC BEESWAX
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		GUM KARAYA, ISOPROPYL MYRISTATE, IMIDAZOLIDINYL UREA,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Classified as expected to be toxic or harmful		DIMETHICONE
Classified as expected to be toxic or harmful		PETROLATUM
Classified as not expected to be potentially toxic or harmful		CAPRYLIC/ CAPRIC TRIGLYCERIDE, CARBOMER, CETEARYL ALCOHOL, PROPYLENE GLYCOL DIPELARGONATE, SQUALANE, WATER, XANTHAN GUM

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		SALICYLIC ACID
Designated as safe for general or specific, limited use in food		ALUMINUM SULFATE, CALCIUM ACETATE, CETYL ALCOHOL, DIMETHICONE, GLYCERIN, GLYCERYL MONOSTEARATE, GUM KARAYA, ISOPROPYL MYRISTATE, ISOPROPYL PALMITATE, LACTIC ACID, METHYLPARABEN, MINERAL OIL, PEG-300, PEG-8 DIOLEATE, PEG-8 DISTEARATE, PETROLATUM, POLYETHYLENE GLYCOL, POTASSIUM SORBATE, PROPYLENE GLYCOL, RETINYL PALMITATE, SALICYLIC ACID, SODIUM LAURYL SULFATE, STEARIC ACID, TOCOPHERYL ACETATE, TRIETHANOLAMINE, UREA, XANTHAN GUM, PEG-100 STEARATE

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as skin irritant		PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	ISOPROPYL MYRISTATE, SODIUM LAURETH SULFATE, SODIUM LAURYL SULFATE
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, LACTIC ACID, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show skin irritation at low doses		ISOPROPYL PALMITATE, METHYLPARABEN, SQUALANE, STEARIC ACID, SYNTHETIC BEESWAX, UREA
One or more animal studies show skin irritation at moderate doses		BISABOLOL, CYCLOMETHICONE, GLYCERIN, MINERAL OIL, POLYETHYLENE GLYCOL, QUATERNIUM-15, SALICYLIC ACID, SODIUM CETEARYL SULFATE, SODIUM HYALURONATE
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		ALUMINUM SULFATE
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MINERAL OIL, TRIETHANOLAMINE
No workplace limits set		LACTIC ACID

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		CALCIUM ACETATE
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		SODIUM LAURYL SULFATE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		ALUMINUM SULFATE, CYCLOMETHICONE, GLYCERIN, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		METHYLPARABEN