Woodridge Labs || Skin Deep: Cosmetic Safety Reviews

Manufacturer: Woodridge Labs

Brands: Firminol-10, Psssssst, Vita-K, Vita-C2, VITAC2, DermaFreeze365, Woodridge Labs, Skin Appetit

COMPANY SUMMARY

product score range	3	to	8
product count	29		(browse)
ingredient count	126
(why scores have changed)

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this company -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients used by this company:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used by this company: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

See all 29 products by Woodridge Labs

Product type(s) by this company in Skin Deep: anti-aging (2), body firming lotion (1), concealer (1), eczema/damaged skin treatment (1), exfoliant/scrub (1), facial cleanser (1), facial moisturizer/treatment (4), redness/rosacea treatment (1), scar treatment (3), shampoo (2), skin fading/lightener (2), sunscreen: moisturizer (1), varicose/spider vein treatment (3)

ingredients

	score	data gap	products *	concerns
NANO TITANIUM DIOXIDE	2	87%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards, Biochemical or cellular level changes
METHYLPARABEN	10	63%	10 products	Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
ALUMINUM STARCH OCTENYLSUCCINATE	9	74%	2 products	Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ARSENIC, LEAD, HEAVY METALS)
OXYBENZONE (BENZOPHENONE-3)	9	55%	1 products	Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FRAGRANCE	8	100%	5 products	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
CETEARETH-30	5	71%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
POLYETHYLENE	6	69%	1 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
OCTINOXATE (OCTYL METHOXYCINNAMATE)	6	65%	1 products	Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes
FICUS CARICA (FIG) EXTRACT	8	59%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SILICA	1	69%	7 products	Biochemical or cellular level changes
PEG-100 STEARATE	7	69%	4 products	Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE)
BUTYLPARABEN	6	79%	1 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
ISOBUTANE	6	79%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Contamination concerns (BUTADIENE), Occupational hazards
BIS-PEG-12 DIMETHICONE BEESWAX	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
DIHYDROXYPROPYL PEG 5 LINOLEAMMONIUM CHLORIDE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-30 DIPOLYHYDROXYSTEARATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-40 SORBITAN PEROLEATE	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-8 BEESWAX	4	76%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-7 HYDROGENATED CASTOR OIL	4	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PEG-15 STEARYL ETHER	4	73%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
METHYLCHLOROISOTHIAZOLINONE	6	63%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	1 products	Violations, restrictions & warnings, Allergies/immunotoxicity
DIAZOLIDINYL UREA	6	59%	9 products	Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE)
TRIETHANOLAMINE	6	58%	9 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards
ETHYLPARABEN	5	80%	1 products	Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SD ALCOHOL 40	5	77%	2 products	Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (BRUCINE, T-BUTYL ALCOHOL, BRUCINE SULFATE, QUASSIN)
PROPYLPARABEN	5	71%	4 products	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
D&C RED 17	2	70%	1 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
RETINYL PALMITATE	5	68%	1 products	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
PROPRIETARY INGREDIENTS	4	100%	2 products	Miscellaneous
UNSPECIFIED EXTRACTS	4	100%	2 products	Miscellaneous
TITANIUM DIOXIDE (NON-NANO)	1	81%	4 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes
TOCOPHERYL ACETATE	4	81%	6 products	Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE)
PROPANE	4	77%	2 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Occupational hazards
D&C RED 33	4	75%	1 products	Violations, restrictions & warnings
D&C YELLOW 11	0	75%	1 products	none identified
MINERAL OIL	2	73%	3 products	Organ system toxicity (non-reproductive), Occupational hazards
PHENOXYETHANOL	4	67%	2 products	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
PROPYLENE GLYCOL	4	60%	12 products	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption
LAURETH-7	3	100%	2 products	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CYCLOPENTASILOXANE	2	79%	1 products	Persistence and bioaccumulation
DISODIUM EDTA	3	78%	3 products	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	1 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ACRYLATES COPOLYMER	3	75%	2 products	Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE)
MICA	3	75%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards
DIMETHICONE	2	74%	10 products	Violations, restrictions & warnings
POLYACRYLAMIDE	3	71%	2 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE)
PANTHENOL	2	88%	2 products	Multiple, additive exposure sources
VITAMIN K	2	87%	1 products	Developmental/reproductive toxicity, Organ system toxicity (non-reproductive)
IRON OXIDES	2	85%	4 products	Persistence and bioaccumulation, Enhanced skin absorption
CYCLOMETHICONE	2	83%	5 products	Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
FD&C BLUE 1	1	83%	1 products	none identified
ETHOXYDIGLYCOL	2	82%	3 products	Organ system toxicity (non-reproductive)
MAGNESIUM SULFATE	2	82%	2 products	Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	2	81%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
SODIUM C14-16 OLEFIN SULFONATE	2	75%	1 products	Organ system toxicity (non-reproductive), Contamination concerns (GAMMA SULTONE)
GLYCERIN	2	74%	6 products	Organ system toxicity (non-reproductive), Occupational hazards
STEARIC ACID	2	74%	9 products	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
VITIS VINIFERA (GRAPE) SEED EXTRACT	1	100%	2 products	Multiple, additive exposure sources
HAMAMELIS VIRGINIANA (WITCH HAZEL)	1	97%	1 products	none identified
C12-15 ALKYL BENZOATE	0	94%	2 products	none identified
CAPRYLIC/ CAPRIC TRIGLYCERIDE	0	94%	3 products	none identified
ISOHEXADECANE	0	94%	2 products	none identified
C13-14 ISOPARAFFIN	1	93%	2 products	none identified
CETEARYL ALCOHOL	0	93%	1 products	none identified
GLYCOL DISTEARATE	1	93%	1 products	Multiple, additive exposure sources
MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL	1	93%	1 products	Endocrine disruption, Allergies/immunotoxicity
PVM/ MA COPOLYMER	1	93%	2 products	Irritation (skin, eyes, or lungs)
ETHYLHEXYL PALMITATE	1	92%	3 products	Irritation (skin, eyes, or lungs)
SORBITAN STEARATE	1	92%	1 products	none identified
POLYBUTENE	1	92%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ASCORBIC ACID (VITAMIN C)	1	91%	1 products	none identified
ETHYLHEXYLGLYCERIN	1	90%	1 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
YEAST EXTRACT	1	90%	1 products	none identified
ASCORBYL PALMITATE (VITAMIN C PALMITATE)	1	88%	5 products	none identified
GLYCERYL MONOSTEARATE	1	88%	9 products	none identified
SORBITOL	1	88%	1 products	none identified
CETYL ALCOHOL	1	87%	5 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
ISOPROPYL PALMITATE	1	87%	2 products	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
OCTYLDODECANOL	1	87%	1 products	Irritation (skin, eyes, or lungs)
PHYTONADIONE	1	87%	8 products	Organ system toxicity (non-reproductive), Biochemical or cellular level changes
CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL	1	84%	2 products	none identified
STEARYL ALCOHOL	1	84%	1 products	Irritation (skin, eyes, or lungs)
SODIUM HYALURONATE	1	83%	1 products	none identified
TAPIOCA STARCH	1	83%	1 products	Occupational hazards
HYDROXYETHYLCELLULOSE	1	82%	4 products	none identified
CELLULOSE GUM	1	80%	1 products	none identified
BUTYLENE GLYCOL	1	79%	2 products	Irritation (skin, eyes, or lungs)
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT	1	75%	1 products	none identified
ALOE BARBADENSIS (ALOE VERA) JUICE	1	73%	2 products	none identified
ALOE BARBADENSIS (ALOE VERA) GEL	1	72%	5 products	none identified
ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER	0	100%	2 products	none identified
BUTYLENE/ ETHYLENE/ STYRENE COPOLYMER	0	100%	1 products	none identified
CHAMOMILLA RECUTITA (MATRICARIA) FLOWER EXTRACT	0	100%	1 products	none identified
CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT	0	100%	2 products	none identified
DEAD SEA SALT	0	100%	1 products	none identified
DIMETHICONE CROSSPOLYMER	0	100%	1 products	none identified
DIPALMITOYL HYDROXYPROLINE	0	100%	2 products	none identified
EQUISETUM ARVENSE (HORSETAIL) EXTRACT	0	100%	2 products	none identified
ETHYLENE/ PROPYLENE/ STYRENE COPOLYMER	0	100%	1 products	none identified
GLYCYRRHIZA GLABRA (LICORICE) ROOT OIL	0	100%	1 products	none identified
HAMAMELIS VIRGINIANA (WITCH HAZEL) WATER	0	100%	1 products	none identified
NEOPENTYL GLYCOL DIHEPTANOATE	0	100%	1 products	none identified
PALMITOYL OLIGOPEPTIDE	0	100%	2 products	none identified
SODIUM METHYL COCOYL TAURATE	0	100%	1 products	none identified
SUCROSE OLEATE	0	100%	1 products	none identified
THEOBROMA CACAO (CACAO) EXTRACT	0	100%	2 products	none identified
VACCINIUM ANGUSTIFOLIUM (BLUEBERRY) EXTRACT	0	100%	2 products	none identified
BEHENETH-5	0	100%	1 products	none identified
CUCUMIS MELO CANTALUPENSIS FRUIT EXTRACT	0	100%	2 products	none identified
JUGLANS REGIA (PERSIAN WALNUT) SEED EXTRACT	0	100%	2 products	none identified
GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER	0	100%	2 products	none identified
PALMITOYL TETRAPEPTIDE-7	0	100%	2 products	none identified
HYDROLYZED YOGURT PROTEIN	0	100%	2 products	none identified
PRO VITA-K COMPLEX	0	100%	2 products	none identified
MAGNESIUM ASCORBYL PHOSPHATE	0	99%	4 products	none identified
ALLANTOIN	0	94%	1 products	none identified
HONEY EXTRACT	0	94%	2 products	none identified
HYDROLYZED SILK	0	94%	1 products	none identified
MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL	0	94%	1 products	none identified
NYLON-12	0	94%	1 products	none identified
VITIS VINIFERA (GRAPE) SEED OIL	0	94%	1 products	none identified
BEHENYL ALCOHOL	0	93%	1 products	none identified
CARBOMER	0	93%	5 products	none identified
PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL	0	93%	2 products	none identified
WATER	0	0%	13 products	innocuous

* Product counts only include current formulations sold by this company. The company may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this company that have used the ingredient.

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of carcinogenicity	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO), NANO TITANIUM DIOXIDE
Cancer - not classifiable/not likely to be human carcinogen	products that may be aerosolized (airborne)	SILICA
Cancer - not classifiable/not likely to be human carcinogen		D&C RED 17, FD&C BLUE 1, POLYETHYLENE, TRIETHANOLAMINE, VITAMIN K
Not likely to be carcinogenic in humans		STEARIC ACID
Cancer - limited evidence	products that may be aerosolized (airborne)	MINERAL OIL
Cancer - limited evidence		RETINYL PALMITATE, SD ALCOHOL 40
One or more in vitro tests on mammalian cells show positive mutation results		ASCORBIC ACID (VITAMIN C), BUTYLPARABEN, DIAZOLIDINYL UREA, DISODIUM EDTA, ETHYLPARABEN, GLYCERIN, METHYLPARABEN, PROPYLENE GLYCOL, PROPYLPARABEN, SODIUM HYDROXIDE, SORBITOL, TOCOPHERYL ACETATE
One or more animal studies show tumor formation at moderate doses		PEG-100 STEARATE,
One or more animal studies show tumor formation at moderate doses		CYCLOPENTASILOXANE
One or more in vitro tests non-mammalian cells show positive mutation results		D&C RED 33, ETHOXYDIGLYCOL, HAMAMELIS VIRGINIANA (WITCH HAZEL), MAGNESIUM SULFATE, METHYLCHLOROISOTHIAZOLINONE, OXYBENZONE (BENZOPHENONE-3), PHENOXYETHANOL
One or more animal studies show tumor formation at high doses		CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CELLULOSE GUM, STEARYL ALCOHOL

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Limited evidence of reproductive toxicity		SD ALCOHOL 40
Human nervous system toxicant - moderate evidence		ALUMINUM STARCH OCTENYLSUCCINATE
One or more animal studies show any effects at very low doses		BUTYLPARABEN
One or more animal studies show any effects at low doses		PROPYLPARABEN
One or more animal studies show reproductive effects at low doses		RETINYL PALMITATE, VITAMIN K
Limited evidence of developmental toxicity		OXYBENZONE (BENZOPHENONE-3)
One or more animal studies show any effects at moderate doses		ALOE BARBADENSIS (ALOE VERA) GEL, ALOE BARBADENSIS (ALOE VERA) JUICE
One or more animal studies show reproductive effects at moderate doses		CELLULOSE GUM, GLYCERIN, PROPYLENE GLYCOL, SODIUM HYALURONATE,
One or more animal studies show reproductive effects at moderate doses		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show reproductive effects at high doses		BUTYLENE GLYCOL, DISODIUM EDTA, ETHOXYDIGLYCOL, ETHYLPARABEN, HYDROXYETHYLCELLULOSE, MAGNESIUM SULFATE, PEG-100 STEARATE

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN, FICUS CARICA (FIG) EXTRACT
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	products for use around the mouth, lips, eyes, or on damaged skin	D&C RED 17, D&C YELLOW 11
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes	products for use around the eyes	D&C RED 33
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin	products for use on damaged skin	BIS-PEG-12 DIMETHICONE BEESWAX, CETEARETH-30, DIHYDROXYPROPYL PEG 5 LINOLEAMMONIUM CHLORIDE, PEG-15 STEARYL ETHER, PEG-30 DIPOLYHYDROXYSTEARATE, PEG-40 SORBITAN PEROLEATE, PEG-8 BEESWAX, POLYETHYLENE, PEG-100 STEARATE, PEG-7 HYDROGENATED CASTOR OIL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)		PHENOXYETHANOL, OXYBENZONE (BENZOPHENONE-3)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	products for use around the eyes; products for use on the lips	OCTINOXATE (OCTYL METHOXYCINNAMATE)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, RETINYL PALMITATE
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		DIMETHICONE
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics		D&C RED 33, ACRYLATES COPOLYMER, ALOE BARBADENSIS (ALOE VERA) GEL, ALOE BARBADENSIS (ALOE VERA) JUICE, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, ALUMINUM STARCH OCTENYLSUCCINATE, BIS-PEG-12 DIMETHICONE BEESWAX, CETEARETH-30, DIAZOLIDINYL UREA, DIHYDROXYPROPYL PEG 5 LINOLEAMMONIUM CHLORIDE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, PEG-15 STEARYL ETHER, PEG-30 DIPOLYHYDROXYSTEARATE, PEG-40 SORBITAN PEROLEATE, PEG-8 BEESWAX, POLYACRYLAMIDE, POLYETHYLENE, PROPYLENE GLYCOL, SODIUM C14-16 OLEFIN SULFONATE, TRIETHANOLAMINE, PEG-100 STEARATE, PEG-7 HYDROGENATED CASTOR OIL

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Strong evidence of human neurotoxicity		ALUMINUM STARCH OCTENYLSUCCINATE
Moderate evidence of human neurotoxicity		FRAGRANCE
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE, STEARIC ACID
One or more animal studies show brain and nervous system effects at low doses		DISODIUM EDTA
One or more animal studies show any effects at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-30, MAGNESIUM SULFATE, METHYLPARABEN, PHENOXYETHANOL, SODIUM HYALURONATE
One or more animal studies show brain and nervous system effects at high doses		BUTYLENE GLYCOL, DIAZOLIDINYL UREA, ETHOXYDIGLYCOL, FD&C BLUE 1, GLYCERIN, HYDROXYETHYLCELLULOSE, OXYBENZONE (BENZOPHENONE-3), POLYACRYLAMIDE, POLYETHYLENE, PROPYLENE GLYCOL, RETINYL PALMITATE, YEAST EXTRACT
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study		PROPANE, SD ALCOHOL 40
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Human any disruptor - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN
Human any disruptor - moderate evidence		OXYBENZONE (BENZOPHENONE-3)
Limited evidence of any disruption		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL
One or more animal studies show endocrine disruption at moderate doses		CYCLOPENTASILOXANE
One or more animal studies show endocrine system disruption at high doses		BUTYLENE GLYCOL, DIAZOLIDINYL UREA, DISODIUM EDTA, GLYCERIN, TRIETHANOLAMINE

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human immune system toxicant		DIAZOLIDINYL UREA, FICUS CARICA (FIG) EXTRACT, FRAGRANCE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, TRIETHANOLAMINE
Possible human immune system toxicant	products that may be aerosolized (airborne)	MINERAL OIL
Possible human photoallergenic toxicant		OXYBENZONE (BENZOPHENONE-3)
Human any toxicant - strong evidence		ISOBUTANE, PROPANE
Human immune system toxicant - strong evidence	products that may be aerosolized (airborne)	SILICA
Human skin toxicant - strong evidence		BUTYLPARABEN, ETHYLPARABEN, METHYLPARABEN, PROPYLPARABEN, TOCOPHERYL ACETATE
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human immune system toxicant - moderate evidence		POLYETHYLENE
One or more animal studies show immune effects at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO), NANO TITANIUM DIOXIDE
One or more human case studies show possible photoallergic effects		OCTINOXATE (OCTYL METHOXYCINNAMATE)
Limited evidence of any toxicity		MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, PHENOXYETHANOL
One or more animal studies show gastrointestinal effects at moderate doses		MICA

Persistence and bioaccumulation*

*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Persistent, bioaccumulative in wildlife and humans	products that may be aerosolized (airborne)	SILICA
Persistent, bioaccumulative in wildlife and humans		MICA, IRON OXIDES
Persistent, bioaccumulative in wildlife		CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C RED 17
Ingredient is suspected or measured to accumulate in people		OCTINOXATE (OCTYL METHOXYCINNAMATE), OXYBENZONE (BENZOPHENONE-3)
Not suspected to be persistent		ALLANTOIN, ASCORBIC ACID (VITAMIN C), ASCORBYL PALMITATE (VITAMIN C PALMITATE), BEHENYL ALCOHOL, BUTYLENE GLYCOL, BUTYLPARABEN, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CETEARETH-30, CETEARYL ALCOHOL, DIAZOLIDINYL UREA, DIMETHICONE, DISODIUM EDTA, ETHYLHEXYL PALMITATE, ETHYLPARABEN, GLYCERIN, GLYCERYL MONOSTEARATE, GLYCOL DISTEARATE, ISOPROPYL PALMITATE, MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, METHYLPARABEN, OCTYLDODECANOL, PANTHENOL, PEG-15 STEARYL ETHER, PHENOXYETHANOL, PHYTONADIONE, PROPYLPARABEN, RETINYL PALMITATE, SORBITAN STEARATE, SORBITOL, STEARIC ACID, STEARYL ALCOHOL, PEG-100 STEARATE
Not suspected to be persistent		CETYL ALCOHOL
Not suspected to be bioaccumulative		CARBOMER, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, D&C RED 33, FD&C BLUE 1, ISOHEXADECANE, MAGNESIUM SULFATE, NYLON-12, POLYETHYLENE, PVM/ MA COPOLYMER, TOCOPHERYL ACETATE, WATER
Not suspected to be bioaccumulative		ISOBUTANE, POLYACRYLAMIDE, PROPANE, SODIUM HYDROXIDE, TITANIUM DIOXIDE (NON-NANO), TRIETHANOLAMINE, POLYBUTENE, NANO TITANIUM DIOXIDE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Known human any toxicant		METHYLPARABEN, FICUS CARICA (FIG) EXTRACT
Known human respiratory toxicant	products that may be aerosolized (airborne)	SILICA
Limited evidence of eye toxicity	products for use around the eyes	ETHYLHEXYLGLYCERIN, TETRASODIUM EDTA
Limited evidence of respiratory toxicity	products that may be aerosolized (airborne)	PROPYLENE GLYCOL
Possible human immune system toxicant		METHYLCHLOROISOTHIAZOLINONE, POLYETHYLENE, TRIETHANOLAMINE, MICA
One or more animal studies show blood effects at very low doses		PHYTONADIONE, MAGNESIUM SULFATE, GLYCERIN, SODIUM HYDROXIDE,
One or more animal studies show respiratory effects at very low doses	products that may be aerosolized (airborne)	STEARIC ACID, TITANIUM DIOXIDE (NON-NANO), NANO TITANIUM DIOXIDE
One or more animal studies show sense organ effects at very low doses	products for use around the eyes, mouth, or lips	PHENOXYETHANOL
One or more animal studies show broad systemic effects at low doses		DISODIUM EDTA, ISOPROPYL PALMITATE,
One or more animal studies show sense organ effects at low doses	products for use around the eyes, mouth, or lips	CETEARETH-30, ETHOXYDIGLYCOL, MINERAL OIL
Limited evidence of any toxicity		ALUMINUM STARCH OCTENYLSUCCINATE, VITAMIN K, SD ALCOHOL 40, BIS-PEG-12 DIMETHICONE BEESWAX, BUTYLPARABEN, DIHYDROXYPROPYL PEG 5 LINOLEAMMONIUM CHLORIDE, ETHYLPARABEN, PEG-15 STEARYL ETHER, PEG-30 DIPOLYHYDROXYSTEARATE, PEG-40 SORBITAN PEROLEATE, PEG-8 BEESWAX, PROPYLPARABEN, PEG-100 STEARATE, PEG-7 HYDROGENATED CASTOR OIL, RETINYL PALMITATE
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)		C13-14 ISOPARAFFIN
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		ALOE BARBADENSIS (ALOE VERA) GEL, GLYCERYL MONOSTEARATE, TOCOPHERYL ACETATE,
One or more animal studies show cardiovascular effects at moderate doses (low dose studies may be unavailable for this ingredient)		OXYBENZONE (BENZOPHENONE-3), FD&C BLUE 1, PROPANE
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		D&C RED 17, POLYACRYLAMIDE,
One or more animal studies show sense organ effects at moderate doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	BUTYLENE GLYCOL, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CETYL ALCOHOL, CYCLOMETHICONE, CYCLOPENTASILOXANE, OCTYLDODECANOL, SODIUM HYALURONATE, STEARYL ALCOHOL
One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient)		ASCORBYL PALMITATE (VITAMIN C PALMITATE), CELLULOSE GUM, DIAZOLIDINYL UREA, PANTHENOL, TAPIOCA STARCH, HYDROXYETHYLCELLULOSE, SORBITOL,
One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient)		OCTINOXATE (OCTYL METHOXYCINNAMATE)
One or more animal studies show sense organ effects at high doses (low dose studies may be unavailable for this ingredient)	products for use around the eyes, mouth, or lips	YEAST EXTRACT
Classified as expected to be toxic or harmful		DIMETHICONE, ISOHEXADECANE
Classified as expected to be toxic or harmful		ISOBUTANE, SODIUM C14-16 OLEFIN SULFONATE, POLYBUTENE
Classified as not expected to be potentially toxic or harmful		ALLANTOIN, ASCORBIC ACID (VITAMIN C), BEHENYL ALCOHOL, C12-15 ALKYL BENZOATE, CAPRYLIC/ CAPRIC TRIGLYCERIDE, CARBOMER, CETEARYL ALCOHOL, D&C RED 33, D&C YELLOW 11, ETHYLHEXYL PALMITATE, GLYCOL DISTEARATE, HONEY EXTRACT, HYDROLYZED SILK, MACADAMIA TERNIFOLIA (MACADAMIA) SEED OIL, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, METHYLISOTHIAZOLINONE, NYLON-12, PVM/ MA COPOLYMER, SORBITAN STEARATE, IRON OXIDES, VITIS VINIFERA (GRAPE) SEED OIL, WATER, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Ingredient not fully labeled - identity unknown		FRAGRANCE, PROPRIETARY INGREDIENTS, UNSPECIFIED EXTRACTS
Occupational hazards related to handling		ISOBUTANE, PROPANE, SD ALCOHOL 40, SODIUM HYDROXIDE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Used in food or as an additive with limited or no toxicity information available		GLYCOL DISTEARATE, ISOBUTANE, PANTHENOL, PROPANE, SD ALCOHOL 40, VITIS VINIFERA (GRAPE) SEED EXTRACT
Designated as safe for general or specific, limited use in food	products that may be aerosolized (airborne)	SILICA
Designated as safe for general or specific, limited use in food		ALOE BARBADENSIS (ALOE VERA) GEL, ALUMINUM STARCH OCTENYLSUCCINATE, ASCORBIC ACID (VITAMIN C), ASCORBYL PALMITATE (VITAMIN C PALMITATE), BIS-PEG-12 DIMETHICONE BEESWAX, BUTYLENE GLYCOL, BUTYLPARABEN, CELLULOSE GUM, CETYL ALCOHOL, DIHYDROXYPROPYL PEG 5 LINOLEAMMONIUM CHLORIDE, DIMETHICONE, DISODIUM EDTA, ETHOXYDIGLYCOL, FD&C BLUE 1, GLYCERIN, GLYCERYL MONOSTEARATE, ISOBUTANE, ISOPROPYL PALMITATE, MAGNESIUM SULFATE, MELALEUCA ALTERNIFOLIA (TEA TREE) LEAF OIL, METHYLPARABEN, MINERAL OIL, PEG-15 STEARYL ETHER, PEG-30 DIPOLYHYDROXYSTEARATE, PEG-40 SORBITAN PEROLEATE, PEG-8 BEESWAX, POLYACRYLAMIDE, POLYETHYLENE, PROPANE, PROPYLENE GLYCOL, PROPYLPARABEN, RETINYL PALMITATE, SODIUM HYDROXIDE, SORBITAN STEARATE, SORBITOL, STEARIC ACID, STEARYL ALCOHOL, IRON OXIDES, TETRASODIUM EDTA, THEOBROMA CACAO (CACAO) EXTRACT, TITANIUM DIOXIDE (NON-NANO), TOCOPHERYL ACETATE, TRIETHANOLAMINE, VITAMIN K, YEAST EXTRACT, PEG-100 STEARATE, PEG-7 HYDROGENATED CASTOR OIL, TAPIOCA STARCH, NANO TITANIUM DIOXIDE, PRO VITA-K COMPLEX

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Classified as irritant		ETHYLHEXYLGLYCERIN, PHENOXYETHANOL, PROPYLENE GLYCOL
Human any irritant - strong evidence	products for use around the eyes, on the skin, or may be aerosolized (airborne)	BUTYLENE GLYCOL, ETHYLHEXYL PALMITATE, ISOBUTANE, OCTYLDODECANOL, POLYETHYLENE, PROPANE, STEARYL ALCOHOL, POLYBUTENE
One or more animal studies show skin irritation at very low doses		CETYL ALCOHOL, SODIUM HYDROXIDE, TRIETHANOLAMINE, PEG-100 STEARATE
One or more animal studies show significant but moderate pulmonary irritation at low doses	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show significant but moderate pulmonary irritation at low doses		NANO TITANIUM DIOXIDE
One or more animal studies show skin irritation at low doses		CETEARETH-30, ISOPROPYL PALMITATE, METHYLPARABEN, PVM/ MA COPOLYMER, STEARIC ACID, TETRASODIUM EDTA
One or more animal studies show skin irritation at moderate doses		BUTYLPARABEN, CARTHAMNUS TINCTORIUS (SAFFLOWER) OIL, CYCLOMETHICONE, CYCLOPENTASILOXANE, ETHOXYDIGLYCOL, GLYCERIN, MINERAL OIL, SODIUM HYALURONATE, SORBITAN STEARATE, TAPIOCA STARCH
Not likely to be a skin irritant in humans		OXYBENZONE (BENZOPHENONE-3)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		TITANIUM DIOXIDE (NON-NANO), NANO TITANIUM DIOXIDE, PHENOXYETHANOL, TETRASODIUM EDTA
Allowed workplace exposures restricted to low doses		MICA
Allowed workplace exposures restricted to moderate doses		GLYCERIN, MINERAL OIL, TRIETHANOLAMINE, TAPIOCA STARCH
Allowed workplace exposures restricted to high doses		ISOBUTANE, PROPANE
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood		SILICA, NANO TITANIUM DIOXIDE,
One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood	products that may be aerosolized (airborne)	TITANIUM DIOXIDE (NON-NANO)
One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood		D&C RED 17, PHYTONADIONE
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		CELLULOSE GUM, CYCLOMETHICONE, CYCLOPENTASILOXANE, GLYCERIN, MAGNESIUM SULFATE, POLYACRYLAMIDE, POLYETHYLENE, PROPYLENE GLYCOL
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.		OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, OCTINOXATE (OCTYL METHOXYCINNAMATE)
Interferes with gene expresion		BUTYLPARABEN, METHYLPARABEN