

Compact for Safe Cosmetics
|
Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients used by this company -- not the products -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| Ingredients used by this company: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used by this company: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
See all 39 products by Z. Bigatti
Product type(s) by this company in Skin Deep: anti-aging (11), around-eye cream (3), body firming lotion (1), cuticle treatment (1), exfoliant/scrub (1), facial cleanser (2), facial moisturizer/treatment (14), hand cream (1), lip balm (2), lip plumper (1), makeup remover (1), mask (4), moisturizer (1), sunscreen: moisturizer (1), toners/astringents (2)
| score | data gap | products * | concerns | |
| METHYLPARABEN | 10 | 63% | 19 products | Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| OXYBENZONE (BENZOPHENONE-3) | 9 | 55% | 5 products | Developmental/reproductive toxicity, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| PEG-40 CASTOR OIL | 6 | 72% | 2 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| OCTINOXATE (OCTYL METHOXYCINNAMATE) | 6 | 65% | 1 products | Endocrine disruption, Allergies/immunotoxicity, Persistence and bioaccumulation, Enhanced skin absorption, Biochemical or cellular level changes |
| PEG-40 STEARATE | 7 | 70% | 10 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-8 STEARATE | 4 | 70% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-100 STEARATE | 7 | 69% | 10 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| SALICYLIC ACID | 7 | 66% | 4 products | Violations, restrictions & warnings, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Enhanced skin absorption |
| BUTYLPARABEN | 6 | 79% | 2 products | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PEG-10 RAPESEED STEROL | 4 | 76% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| PEG-40 HYDROGENATED CASTOR OIL | 4 | 75% | 1 products | Organ system toxicity (non-reproductive), Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| TRIETHANOLAMINE | 6 | 58% | 4 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES), Occupational hazards |
| ETHYLPARABEN | 5 | 80% | 2 products | Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| CYCLOTETRASILOXANE | 5 | 76% | 2 products | Developmental/reproductive toxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| D&C ORANGE 4 | 4 | 72% | 10 products | Developmental/reproductive toxicity, Violations, restrictions & warnings |
| PROPYLPARABEN | 5 | 71% | 18 products | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| IMIDAZOLIDINYL UREA | 5 | 70% | 5 products | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| LACTIC ACID | 5 | 70% | 7 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| VITAMIN A | 5 | 70% | 6 products | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| RETINYL PALMITATE | 5 | 68% | 9 products | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PAPAIN | 5 | 68% | 5 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| LINALOOL | 5 | 65% | 6 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| PROPRIETARY INGREDIENTS | 4 | 100% | 2 products | Miscellaneous |
| UNSPECIFIED EXTRACTS | 4 | 100% | 1 products | Miscellaneous |
| MYRISTYL MYRISTATE | 1 | 89% | 1 products | Irritation (skin, eyes, or lungs) |
| MAGNESIUM ALUMINUM SILICATE | 4 | 88% | 1 products | Developmental/reproductive toxicity, Neurotoxicity, Organ system toxicity (non-reproductive) |
| BROMELAIN | 3 | 84% | 3 products | Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| TITANIUM DIOXIDE (NON-NANO) | 1 | 81% | 2 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards, Biochemical or cellular level changes |
| TOCOPHERYL ACETATE | 4 | 81% | 15 products | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| FOLIC ACID | 4 | 79% | 12 products | Developmental/reproductive toxicity, Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive) |
| TANNIC ACID | 3 | 79% | 1 products | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive) |
| CAFFEINE | 4 | 75% | 2 products | Developmental/reproductive toxicity, Neurotoxicity, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| D&C RED 33 | 1 | 75% | 1 products | none identified |
| ORYZA SATIVA (RICE) BRAN EXTRACT | 4 | 75% | 1 products | Contamination concerns (GOSSYPOL, HEAVY METALS, PESTICIDES) |
| BETA HYDROXY ACIDS | 4 | 74% | 2 products | Violations, restrictions & warnings, Multiple, additive exposure sources, Enhanced skin absorption |
| FD&C RED 4 | 4 | 73% | 8 products | Violations, restrictions & warnings |
| MINERAL OIL | 2 | 73% | 7 products | Organ system toxicity (non-reproductive), Occupational hazards |
| GLYCOLIC ACID | 4 | 70% | 4 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| SODIUM LACTATE | 4 | 70% | 3 products | Violations, restrictions & warnings |
| OCTISALATE | 3 | 68% | 1 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PHENOXYETHANOL | 4 | 67% | 14 products | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| UREA | 4 | 67% | 5 products | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PROPYLENE GLYCOL | 4 | 60% | 17 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| LAURETH-7 | 3 | 100% | 7 products | Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE) |
| ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT | 3 | 89% | 1 products | Allergies/immunotoxicity, Multiple, additive exposure sources |
| ISOBUTYLPARABEN | 3 | 83% | 2 products | Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| FD&C YELLOW 5 | 2 | 82% | 8 products | Neurotoxicity, Organ system toxicity (non-reproductive) |
| ARGININE | 3 | 79% | 13 products | Neurotoxicity, Organ system toxicity (non-reproductive) |
| CYCLOPENTASILOXANE | 2 | 79% | 3 products | Persistence and bioaccumulation |
| SODIUM HYDROXIDE | 3 | 77% | 7 products | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ACRYLATES COPOLYMER | 3 | 75% | 2 products | Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE) |
| MICA | 3 | 75% | 3 products | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Occupational hazards |
| AMMONIUM POLYACRYLATE | 3 | 74% | 2 products | Contamination concerns (METHACRYLIC ACID, ACRYLIC ACID, 2-ETHYLHEXYL ACRYLATE) |
| DIMETHICONE | 2 | 74% | 11 products | Violations, restrictions & warnings |
| GLYCERYL LINOLENATE | 3 | 74% | 5 products | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (GLYCERYL DIESTERS) |
| GLYCERYL HYDROXYSTEARATE | 3 | 73% | 8 products | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (GLYCERYL DIESTERS) |
| MENTHA PIPERITA (PEPPERMINT) OIL | 3 | 73% | 1 products | Enhanced skin absorption, Contamination concerns (LIMONENE, MENTHOL, MENTHONE) |
| GLYCERYL LINOLEATE | 3 | 73% | 8 products | Violations, restrictions & warnings, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| BENTONITE | 3 | 72% | 1 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| CITRIC ACID | 3 | 72% | 1 products | Violations, restrictions & warnings, Organ system toxicity (non-reproductive) |
| OCTOCRYLENE | 3 | 71% | 1 products | Violations, restrictions & warnings, Biochemical or cellular level changes |
| POLYACRYLAMIDE | 3 | 71% | 7 products | Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Contamination concerns (ACRYLAMIDE) |
| PETROLATUM | 2 | 94% | 6 products | Organ system toxicity (non-reproductive), Contamination concerns (PAHS) |
| AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT | 2 | 88% | 2 products | Neurotoxicity, Organ system toxicity (non-reproductive) |
| PANTHENOL | 2 | 88% | 14 products | Multiple, additive exposure sources |
| TOCOPHEROL | 2 | 87% | 7 products | Contamination concerns (HYDROQUINONE) |
| ALPHA LIPOIC ACID | 2 | 84% | 2 products | Neurotoxicity, Organ system toxicity (non-reproductive) |
| BETA CAROTENE | 1 | 84% | 1 products | Organ system toxicity (non-reproductive) |
| CYANOCOBALAMIN | 2 | 83% | 13 products | Neurotoxicity, Organ system toxicity (non-reproductive) |
| CYCLOMETHICONE | 2 | 83% | 8 products | Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
| NIACINAMIDE | 2 | 81% | 3 products | Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| TETRASODIUM EDTA | 2 | 81% | 16 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| CASTOR OIL | 2 | 80% | 2 products | Developmental/reproductive toxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| KAOLIN | 1 | 79% | 1 products | Occupational hazards |
| BETULA ALBA (BIRCH) BARK EXTRACT | 2 | 76% | 1 products | Violations, restrictions & warnings |
| CAMELLIA SINENSIS (GREEN TEA) EXTRACT | 2 | 76% | 1 products | Violations, restrictions & warnings |
| CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT | 2 | 76% | 10 products | Violations, restrictions & warnings |
| ALPHA HYDROXY ACIDS | 2 | 75% | 1 products | Violations, restrictions & warnings |
| CHOLESTEROL | 2 | 74% | 9 products | Persistence and bioaccumulation |
| GLYCERIN | 2 | 74% | 16 products | Organ system toxicity (non-reproductive), Occupational hazards |
| STEARIC ACID | 2 | 74% | 1 products | Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| CITRUS AURANTIFOLIA (LIME) OIL | 2 | 73% | 1 products | Violations, restrictions & warnings |
| CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL | 2 | 73% | 4 products | Violations, restrictions & warnings |
| CITRUS AURANTIUM BERGAMIA (BERGAMOT) FRUIT OIL | 2 | 73% | 1 products | Violations, restrictions & warnings |
| SODIUM PCA | 2 | 71% | 8 products | Contamination concerns (NITROSAMINES) |
| SODIUM BENZOATE | 2 | 69% | 3 products | Organ system toxicity (non-reproductive) |
| COMMIPHORA MYRRHA (MYRRH) EXTRACT | 1 | 100% | 1 products | Multiple, additive exposure sources |
| CROCUS SATIVUS (SAFFRON) FLOWER EXTRACT | 1 | 100% | 1 products | Multiple, additive exposure sources |
| MELISSA OFFICINALIS (LEMON BALM) EXTRACT | 1 | 100% | 1 products | Multiple, additive exposure sources |
| VITIS VINIFERA (GRAPE) SEED EXTRACT | 1 | 100% | 17 products | Multiple, additive exposure sources |
| ANGELICA ARCHANGELICA ROOT EXTRACT | 1 | 100% | 3 products | Multiple, additive exposure sources |
| HAMAMELIS VIRGINIANA (WITCH HAZEL) | 1 | 97% | 1 products | none identified |
| ROSA CENTIFOLIA (CABBAGE ROSE) FLOWER EXTRACT | 1 | 97% | 2 products | Irritation (skin, eyes, or lungs) |
| HYDROLYZED WHEAT PROTEIN | 1 | 95% | 1 products | Allergies/immunotoxicity |
| SUPEROXIDE DISMUTASE | 1 | 95% | 13 products | none identified |
| SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT | 1 | 95% | 2 products | Organ system toxicity (non-reproductive) |
| ARACHIDYL ALCOHOL | 0 | 94% | 2 products | none identified |
| BEHENTRIMONIUM CHLORIDE | 0 | 94% | 1 products | none identified |
| C12-15 ALKYL BENZOATE | 0 | 94% | 3 products | none identified |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | 3 products | none identified |
| CUPRESSUS SEMPERVIRENS (ITALIAN CYPRESS) OIL | 1 | 94% | 3 products | Irritation (skin, eyes, or lungs) |
| HYDROLYZED LUPINE PROTEIN | 1 | 94% | 1 products | Multiple, additive exposure sources |
| ISOHEXADECANE | 0 | 94% | 3 products | none identified |
| CITRUS AURANTIUM DULCIS (ORANGE) FRUIT EXTRACT | 1 | 94% | 3 products | Multiple, additive exposure sources |
| POLYISOBUTENE | 1 | 94% | 1 products | Organ system toxicity (non-reproductive) |
| C13-14 ISOPARAFFIN | 1 | 93% | 7 products | none identified |
| CERESIN | 0 | 93% | 8 products | none identified |
| CETEARYL ALCOHOL | 0 | 93% | 3 products | none identified |
| GLYCOL DISTEARATE | 1 | 93% | 1 products | Multiple, additive exposure sources |
| LINOLEIC ACID | 1 | 93% | 9 products | Irritation (skin, eyes, or lungs) |
| PELARGONIUM GRAVEOLENS (GERANIUM) FLOWER OIL | 1 | 93% | 3 products | Organ system toxicity (non-reproductive) |
| SALIX ALBA (WHITE WILLOW) BARK EXTRACT | 1 | 93% | 2 products | Organ system toxicity (non-reproductive) |
| SILYBUM MARIANUM (LADY'S THISTLE) EXTRACT | 1 | 93% | 2 products | none identified |
| SQUALANE | 1 | 93% | 8 products | Irritation (skin, eyes, or lungs) |
| SUTILAINS | 1 | 93% | 1 products | Organ system toxicity (non-reproductive) |
| ETHYLHEXYL PALMITATE | 1 | 92% | 1 products | Irritation (skin, eyes, or lungs) |
| POLYBUTENE | 1 | 92% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ASCORBIC ACID (VITAMIN C) | 1 | 91% | 3 products | none identified |
| BORON NITRIDE | 0 | 91% | 1 products | Enhanced skin absorption |
| CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT | 1 | 91% | 1 products | none identified |
| PANAX GINSENG (GINSENG) ROOT EXTRACT | 1 | 91% | 2 products | none identified |
| GLYCERYL ARACHIDONATE | 1 | 91% | 5 products | Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| GINKGO BILOBA (MAIDENHAIR TREE) LEAF EXTRACT | 1 | 90% | 1 products | none identified |
| GLYCERYL OLEATE | 1 | 90% | 1 products | Irritation (skin, eyes, or lungs) |
| HESPERIDIN METHYL CHALCONE | 1 | 90% | 1 products | none identified |
| YEAST EXTRACT | 1 | 90% | 3 products | none identified |
| PENTYLENE GLYCOL | 1 | 89% | 1 products | none identified |
| COFFEA ARABICA (ARABIAN COFFEE) EXTRACT | 1 | 89% | 1 products | none identified |
| GLUCONIC ACID | 1 | 89% | 1 products | Organ system toxicity (non-reproductive) |
| JUNIPERUS COMMUNIS FRUIT OIL | 1 | 89% | 3 products | Irritation (skin, eyes, or lungs) |
| FOENICULUM VULGARE (FENNEL) OIL | 1 | 88% | 3 products | Irritation (skin, eyes, or lungs) |
| GLYCERYL MONOSTEARATE | 1 | 88% | 13 products | none identified |
| GLYCINE SOJA (SOYBEAN) OIL | 1 | 88% | 4 products | none identified |
| OLEA EUROPAEA (OLIVE) OIL | 1 | 88% | 1 products | Irritation (skin, eyes, or lungs) |
| ROSMARINUS OFFICINALIS (ROSEMARY) LEAF OIL | 1 | 88% | 3 products | Irritation (skin, eyes, or lungs) |
| SORBITOL | 1 | 88% | 3 products | none identified |
| SQUALENE | 1 | 88% | 1 products | none identified |
| THYMUS VULGARIS (COMMON THYME) OIL | 1 | 88% | 3 products | Irritation (skin, eyes, or lungs) |
| TRIDECETH-9 | 1 | 88% | 1 products | Organ system toxicity (non-reproductive) |
| XYLITOL | 1 | 88% | 2 products | none identified |
| ZINGIBER OFFICINALE (GINGER) ROOT OIL | 1 | 88% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| STEARETH-20 | 1 | 88% | 1 products | none identified |
| CETYL ALCOHOL | 1 | 87% | 11 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| ISOPROPYL PALMITATE | 1 | 87% | 2 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| PERSEA GRATISSIMA (AVOCADO) OIL | 1 | 87% | 3 products | Irritation (skin, eyes, or lungs) |
| PHYTONADIONE | 1 | 87% | 4 products | Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| VITAMIN B3 | 1 | 87% | 5 products | none identified |
| EUCALYPTUS GLOBULUS (EUCALYPTUS) LEAF OIL | 1 | 86% | 3 products | Irritation (skin, eyes, or lungs) |
| GLUCOSAMINE HCL | 1 | 86% | 3 products | none identified |
| ISOPROPYL MYRISTATE | 1 | 86% | 1 products | Irritation (skin, eyes, or lungs) |
| TRIBEHENIN | 1 | 86% | 2 products | Enhanced skin absorption |
| VITAMIN B2 | 1 | 86% | 5 products | Organ system toxicity (non-reproductive) |
| RIBOFLAVIN | 1 | 86% | 7 products | Organ system toxicity (non-reproductive) |
| FRUCTOSE | 1 | 85% | 3 products | none identified |
| NIACIN | 1 | 85% | 7 products | none identified |
| HYDROLYZED ALGIN | 1 | 84% | 2 products | Organ system toxicity (non-reproductive) |
| MYRISTYL ALCOHOL | 1 | 84% | 1 products | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| POLYSORBATE-20 | 1 | 84% | 1 products | none identified |
| SESAMUM INDICUM (SESAME) SEED OIL | 1 | 84% | 1 products | Organ system toxicity (non-reproductive) |
| STEARYL ALCOHOL | 1 | 84% | 9 products | Irritation (skin, eyes, or lungs) |
| SODIUM HYALURONATE | 1 | 83% | 15 products | none identified |
| HYDROXYETHYLCELLULOSE | 1 | 82% | 1 products | none identified |
| POLYSORBATE-60 | 1 | 81% | 3 products | none identified |
| PVP | 1 | 81% | 1 products | Organ system toxicity (non-reproductive) |
| ANTHEMIS NOBILIS (CHAMOMILE) LEAF EXTRACT | 1 | 80% | 1 products | Enhanced skin absorption |
| BUTYLENE GLYCOL | 1 | 79% | 18 products | Irritation (skin, eyes, or lungs) |
| GLYCINE | 1 | 79% | 4 products | none identified |
| DIPOTASSIUM GLYCYRRHIZATE | 1 | 75% | 2 products | none identified |
| MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT | 1 | 75% | 1 products | Enhanced skin absorption |
| GLYCERYL DISTEARATE | 1 | 74% | 9 products | none identified |
| ALOE BARBADENSIS (ALOE VERA) GEL | 1 | 72% | 4 products | none identified |
| ACETYL HEXAPEPTIDE-3 | 0 | 100% | 1 products | none identified |
| ACRYLATES/ C10-30 ALKYL ACRYLATE CROSSPOLYMER | 0 | 100% | 3 products | none identified |
| AMINOPROPYL ASCORBYL PHOSPHATE | 0 | 100% | 4 products | none identified |
| ANANAS SATIVUS (PINEAPPLE) FRUIT EXTRACT | 0 | 100% | 2 products | none identified |
| ARACHIDYL GLUCOSIDE | 0 | 100% | 2 products | none identified |
| ARNICA MONTANA (ARNICA) FLOWER EXTRACT | 0 | 100% | 1 products | none identified |
| ARTEMISIA VULGARIS (MUGWORT) EXTRACT | 0 | 100% | 2 products | none identified |
| BAMBUSA VULGARIS (BAMBOO) EXTRACT | 0 | 100% | 2 products | none identified |
| BASSIA LATIFOLIA SEED BUTTER | 0 | 100% | 1 products | none identified |
| CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) LEAF EXTRACT | 0 | 100% | 8 products | none identified |
| CAMELLIA OLEIFERA (TEA-OIL CAMELLIA) SEED EXTRACT | 0 | 100% | 6 products | none identified |
| CARICA PAPAYA (PAPAYA) | 0 | 100% | 1 products | none identified |
| CARICA PAPAYA (PAPAYA) FRUIT EXTRACT | 0 | 100% | 1 products | none identified |
| CERAMIDE 2 | 0 | 100% | 1 products | none identified |
| CETEARYL GLUCOSIDE | 0 | 100% | 1 products | none identified |
| CETEARYL OLIVATE | 0 | 100% | 1 products | none identified |
| CHAMOMILLA RECUTITA (MATRICARIA) FLOWER EXTRACT | 0 | 100% | 1 products | none identified |
| CHLORELLA VULGARIS (DERMOCHLORELLA ALGAE) EXTRACT | 0 | 100% | 2 products | none identified |
| COCO-GLUCOSIDE | 0 | 100% | 3 products | none identified |
| CORN STARCH, MODIFIED | 0 | 100% | 12 products | none identified |
| CUCUMIS SATIVUS (CUCUMBER) OIL | 0 | 100% | 1 products | none identified |
| CUCUMIS SATIVUS (CUCUMBER) FRUIT EXTRACT | 0 | 100% | 4 products | none identified |
| DAUCUS CAROTA SATIVA (CARROT) ROOT | 0 | 100% | 8 products | none identified |
| DIMETHICONOL | 0 | 100% | 1 products | none identified |
| DIPEPTIDE-2 | 0 | 100% | 1 products | none identified |
| ENZYME MIXTURE | 0 | 100% | 1 products | none identified |
| ETHYL ESTER OF HYDROLYZED SILK | 0 | 100% | 2 products | none identified |
| EUCALYPTUS GLOBULUS (TASMANIAN BLUE GUM) OIL | 0 | 100% | 1 products | none identified |
| FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT | 0 | 100% | 1 products | none identified |
| FOMES OFFICINALIS (TRUNK ROT) EXTRACT | 0 | 100% | 2 products | none identified |
| GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT | 0 | 100% | 1 products | none identified |
| HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT | 0 | 100% | 2 products | none identified |
| HYDROLYZED ALGAE EXTRACT | 0 | 100% | 1 products | none identified |
| HYDROLYZED SOY FLOUR | 0 | 100% | 1 products | none identified |
| LARREA DIVARICATA | 0 | 100% | 1 products | none identified |
| LARREA DIVARICATA (CREOSOTE BUSH) EXTRACT | 0 | 100% | 2 products | none identified |
| LAVANDULA ANGUSTIFOLIA (LAVENDER) FLOWER OIL | 0 | 100% | 1 products | none identified |
| MALVA SYLVESTRIS (COMMON MALLOW) EXTRACT | 0 | 100% | 1 products | none identified |
| MORUS SPECIES (MULBERRY) EXTRACT | 0 | 100% | 1 products | none identified |
| MUSHROOM EXTRACT | 0 | 100% | 1 products | none identified |
| NASTURTIUM OFFICINALE (WATERCRESS) EXTRACT | 0 | 100% | 3 products | none identified |
| NYMPHAEA ALBA (WHITE WATER LILY) FLOWER EXTRACT | 0 | 100% | 2 products | none identified |
| ORANGE | 0 | 100% | 1 products | none identified |
| ORCHIS MACULATA FLOWER EXTRACT | 0 | 100% | 1 products | none identified |
| ORCHIS MASCULA (EARLY-PURPLE ORCHID) FLOWER EXTRACT | 0 | 100% | 3 products | none identified |
| PALMITOYL HYDROLYZED WHEAT PROTEIN | 0 | 100% | 1 products | none identified |
| PALMITOYL OLIGOPEPTIDE | 0 | 100% | 2 products | none identified |
| PALMITOYL TETRAPEPTIDE-3 | 0 | 100% | 1 products | none identified |
| PANAX GINSENG (GINSENG) EXTRACT | 0 | 100% | 2 products | none identified |
| PERSEA GRATISSIMA (AVOCADO) FRUIT OIL | 0 | 100% | 1 products | none identified |
| PISUM SATIVUM (PEA) | 0 | 100% | 1 products | none identified |
| PROPOLIS EXTRACT | 0 | 100% | 1 products | none identified |
| PYRUS MALUS (APPLE) FRUIT EXTRACT | 0 | 100% | 4 products | none identified |
| QUERCUS ALBA (WHITE OAK) BARK EXTRACT | 0 | 100% | 2 products | none identified |
| ROSA CANINA (DOG ROSE) EXTRACT | 0 | 100% | 1 products | none identified |
| ROSA CANINA (DOG ROSE) FRUIT EXTRACT | 0 | 100% | 3 products | none identified |
| ROSA CANINA (DOG ROSE) SEED EXTRACT | 0 | 100% | 1 products | none identified |
| ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT | 0 | 100% | 1 products | none identified |
| RUMEX CRISPUS (YELLOW DOCK) ROOT EXTRACT | 0 | 100% | 1 products | none identified |
| RUSCUS ACULEATUS (BOX HOLLY) ROOT EXTRACT | 0 | 100% | 1 products | none identified |
| SACCHARUM OFFICINARUM (SUGAR CANE) EXTRACT | 0 | 100% | 4 products | none identified |
| SAMBUCUS NIGRA (ELDER) FLOWER EXTRACT | 0 | 100% | 1 products | none identified |
| SCHIZANDRA CHINENSIS (SCHIZANDRA BERRY) FRUIT EXTRACT | 0 | 100% | 2 products | none identified |
| SOLANUM TUBEROSUM (POTATO) EXTRACT | 0 | 100% | 1 products | none identified |
| TETRAHEXYLDECYL ASCORBATE | 0 | 100% | 1 products | none identified |
| TRIPEPTIDE-1 | 0 | 100% | 1 products | none identified |
| TRITICUM VULGARE (WHEAT) GERM EXTRACT | 0 | 100% | 1 products | none identified |
| VERONICA OFFICINALIS (SPEEDWELL) EXTRACT | 0 | 100% | 1 products | none identified |
| VITAMIN F | 0 | 100% | 4 products | none identified |
| VITIS VINIFERA (GRAPE) SEED | 0 | 100% | 5 products | none identified |
| ZINGIBER OFFICINALE (GINGER) ROOT EXTRACT | 0 | 100% | 1 products | none identified |
| ACETYL GLUTAMYL HEPTAPEPTIDE-1 | 0 | 100% | 1 products | none identified |
| ACHILLEA MILLEFOLIUM (COMMON YARROW) | 0 | 100% | 1 products | none identified |
| ANHYDROXYLITOL | 0 | 100% | 2 products | none identified |
| CHAMOMILLA RECUTITA (MATRICARIA) EXTRACT | 0 | 100% | 1 products | none identified |
| CITRUS MEDICA LIMONUM (LEMON) PEEL EXTRACT | 0 | 100% | 3 products | none identified |
| COLEUS FORSKOHLII ROOT OIL | 0 | 100% | 1 products | none identified |
| EQUISETUM HIEMALE EXTRACT | 0 | 100% | 3 products | none identified |
| EUCALYPTUS GLOBULUS | 0 | 100% | 4 products | none identified |
| HYDROLYZED SESAME EXTRACT | 0 | 100% | 1 products | none identified |
| LEMON EKISU | 0 | 100% | 3 products | none identified |
| MACROCYSTIS PYRIFERA EXTRACT | 0 | 100% | 7 products | none identified |
| PENTAPEPTIDE-1 | 0 | 100% | 1 products | none identified |
| PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES WATER | 0 | 100% | 1 products | none identified |
| PISUM SATIVUM (PEA) EXTRACT | 0 | 100% | 2 products | none identified |
| PRIMULA VERIS EXTRACT | 0 | 100% | 1 products | none identified |
| SEA WATER | 0 | 100% | 2 products | none identified |
| SODIUM PALMITOYL PROLINE | 0 | 100% | 2 products | none identified |
| TARAXACUM OFFICINALE (DANDELION) EXTRACT | 0 | 100% | 5 products | none identified |
| TERMINALIA CATAPPA LEAF EXTRACT | 0 | 100% | 1 products | none identified |
| XYLOGLUCAN | 0 | 100% | 2 products | none identified |
| LEMON | 0 | 100% | 1 products | none identified |
| MIMOSA TENUIFLORA EXTRACT | 0 | 100% | 1 products | none identified |
| CYCLIC HYDROXY ACID | 0 | 100% | 4 products | none identified |
| SODIUM HYDROXYETHYL ACRYLATE/ACRYLOYLDIMETHYL TAURATE COPOLYMER | 0 | 100% | 3 products | none identified |
| SORBITAN ISOSTEARATE | 0 | 99% | 1 products | none identified |
| SORBITAN OLIVATE | 0 | 99% | 1 products | none identified |
| SAPONIFIED PERSEA GRATISSIMA (AVOCADO) OIL | 0 | 99% | 1 products | none identified |
| ACRYLAMIDE/ AMMONIUM ACRYLATE COPOLYMER | 0 | 94% | 1 products | none identified |
| ALGAE EXTRACT | 0 | 94% | 7 products | none identified |
| ALLANTOIN | 0 | 94% | 1 products | none identified |
| BUTYROSPERMUM PARKII (SHEA BUTTER) | 0 | 94% | 12 products | none identified |
| CAPRYLYL GLYCOL | 0 | 94% | 1 products | none identified |
| COCONUT ALCOHOL | 0 | 94% | 2 products | none identified |
| CYMBOPOGON SCHOENANTHUS (LEMONGRASS) EXTRACT | 0 | 94% | 4 products | none identified |
| GLYCINE SOJA PROTEIN | 0 | 94% | 2 products | none identified |
| HELIANTHUS ANNUUS (SUNFLOWER) OIL | 0 | 94% | 1 products | none identified |
| HONEY EXTRACT | 0 | 94% | 1 products | none identified |
| HUMULUS LUPULUS (HOPS) EXTRACT | 0 | 94% | 2 products | none identified |
| HYALURONIC ACID | 0 | 94% | 1 products | none identified |
| HYDROGENATED VEGETABLE OIL | 0 | 94% | 2 products | none identified |
| HYDROLYZED SILK | 0 | 94% | 1 products | none identified |
| HYDROLYZED GLYCINE SOJA (SOY) PROTEIN | 0 | 94% | 6 products | none identified |
| INOSITOL | 0 | 94% | 3 products | none identified |
| NYLON-12 | 0 | 94% | 1 products | none identified |
| OENOTHERA BIENNIS (EVENING PRIMROSE) OIL | 0 | 94% | 1 products | none identified |
| PRUNUS ARMENIACA (APRICOT) KERNEL OIL | 0 | 94% | 4 products | none identified |
| ROYAL JELLY | 0 | 94% | 1 products | none identified |
| SERINE | 0 | 94% | 1 products | none identified |
| VITIS VINIFERA (GRAPE) SEED OIL | 0 | 94% | 5 products | none identified |
| XANTHAN GUM | 0 | 94% | 7 products | none identified |
| DITHIAOCTANEDIOL | 0 | 94% | 1 products | none identified |
| PERSEA GRATISSIMA (AVOCADO) OIL UNSAPONIFIABLES | 0 | 94% | 1 products | none identified |
| BEESWAX | 0 | 93% | 2 products | none identified |
| BEHENYL ALCOHOL | 0 | 93% | 2 products | none identified |
| CARBOMER | 0 | 93% | 4 products | none identified |
| LANOLIN WAX | 0 | 93% | 1 products | none identified |
| PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL | 0 | 93% | 2 products | none identified |
| SACCHAROMYCES/XYLINUM BLACK TEA FERMENT | 0 | 93% | 1 products | none identified |
| HONEY | 0 | 0% | 1 products | innocuous |
| SODIUM CHLORIDE | 0 | 0% | 3 products | innocuous |
| WATER | 0 | 0% | 19 products | innocuous |
* Product counts only include current formulations sold by this company. The company may have other discontinued formulations that use this ingredient. Clicking on the link "X products" will identify all product formulations by this company that have used the ingredient.
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of developmental toxicity | CYCLOTETRASILOXANE, CASTOR OIL | |
| Human nervous system toxicant - moderate evidence | MAGNESIUM ALUMINUM SILICATE | |
| One or more animal studies show any effects at very low doses | BUTYLPARABEN | |
| One or more animal studies show reproductive effects at very low doses | FOLIC ACID | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN | |
| One or more animal studies show reproductive effects at low doses | CAFFEINE, D&C ORANGE 4, RETINYL PALMITATE, TANNIC ACID, VITAMIN A | |
| Limited evidence of developmental toxicity | OXYBENZONE (BENZOPHENONE-3) | |
| One or more animal studies show any effects at moderate doses | ALOE BARBADENSIS (ALOE VERA) GEL | |
| One or more animal studies show reproductive effects at moderate doses | ARGININE, BETA CAROTENE, CHOLESTEROL, CYANOCOBALAMIN, GLYCERIN, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM HYALURONATE, | |
| One or more animal studies show reproductive effects at moderate doses | OCTINOXATE (OCTYL METHOXYCINNAMATE) | |
| One or more animal studies show reproductive effects at high doses | ALPHA LIPOIC ACID, BUTYLENE GLYCOL, ETHYLPARABEN, FD&C YELLOW 5, GLYCOLIC ACID, HESPERIDIN METHYL CHALCONE, HYDROXYETHYLCELLULOSE, KAOLIN, PEG-40 STEARATE, PEG-8 STEARATE, POLYSORBATE-20, POLYSORBATE-60, SODIUM BENZOATE, UREA, PAPAIN, PEG-100 STEARATE | |
| Possible human reproductive or developmental toxin | MYRISTYL MYRISTATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN | |
| Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only | products for use around the mouth, lips, eyes, or on damaged skin | D&C ORANGE 4, FD&C RED 4 |
| Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes | products for use around the eyes | D&C RED 33 |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Allowable pH limits | GLYCOLIC ACID, LACTIC ACID, SODIUM LACTATE | |
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use on injured or damaged skin | products for use on damaged skin | PEG-10 RAPESEED STEROL, PEG-40 CASTOR OIL, PEG-40 HYDROGENATED CASTOR OIL, PEG-40 STEARATE, PEG-8 STEARATE, PEG-100 STEARATE |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit) | OCTOCRYLENE, PHENOXYETHANOL, OCTISALATE, OXYBENZONE (BENZOPHENONE-3) | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | products for use around the eyes; products for use on the lips | OCTINOXATE (OCTYL METHOXYCINNAMATE) |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | ALPHA HYDROXY ACIDS, BETA HYDROXY ACIDS, CITRIC ACID, GLYCOLIC ACID, LACTIC ACID, RETINYL PALMITATE, SALICYLIC ACID, UREA, VITAMIN A | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only if satisfies manufacturing specifications or purity limits, according to industry safety panel (International Fragrance Association) | BETULA ALBA (BIRCH) BARK EXTRACT, LINALOOL, CAMELLIA SINENSIS (GREEN TEA) EXTRACT, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, CITRUS AURANTIFOLIA (LIME) OIL, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, CITRUS AURANTIUM BERGAMIA (BERGAMOT) FRUIT OIL, BENTONITE, DIMETHICONE, GLYCERYL HYDROXYSTEARATE, GLYCERYL LINOLENATE, GLYCERYL LINOLEATE | |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics | D&C RED 33, DIPOTASSIUM GLYCYRRHIZATE, ORYZA SATIVA (RICE) BRAN EXTRACT, ACRYLATES COPOLYMER, ALOE BARBADENSIS (ALOE VERA) GEL, AMMONIUM POLYACRYLATE, BETA HYDROXY ACIDS, GLYCERYL DISTEARATE, GLYCOLIC ACID, LACTIC ACID, MENTHA PIPERITA (PEPPERMINT) LEAF EXTRACT, MENTHA PIPERITA (PEPPERMINT) OIL, PEG-10 RAPESEED STEROL, PEG-40 CASTOR OIL, PEG-40 HYDROGENATED CASTOR OIL, PEG-40 STEARATE, PEG-8 STEARATE, POLYACRYLAMIDE, PROPYLENE GLYCOL, SALICYLIC ACID, SODIUM BENZOATE, SODIUM LACTATE, SODIUM PCA, TRIETHANOLAMINE, PEG-100 STEARATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Human any disruptor - strong evidence | BUTYLPARABEN, CYCLOTETRASILOXANE, ETHYLPARABEN, METHYLPARABEN, OCTINOXATE (OCTYL METHOXYCINNAMATE), PROPYLPARABEN | |
| Human any disruptor - moderate evidence | OXYBENZONE (BENZOPHENONE-3) | |
| One or more studies show endocrine system disruption at very low doses | FOLIC ACID | |
| One or more animal studies show endocrine disruption at moderate doses | CYCLOPENTASILOXANE | |
| One or more animal studies show endocrine disruption at moderate doses | ARGININE, HYDROLYZED ALGIN, ISOBUTYLPARABEN, NIACINAMIDE, SODIUM LACTATE | |
| One or more animal studies show endocrine system disruption at high doses | ANTHEMIS NOBILIS (CHAMOMILE) LEAF EXTRACT, BUTYLENE GLYCOL, CAFFEINE, CHOLESTEROL, GLYCERIN, GLYCINE, PVP, SODIUM PCA, TRIETHANOLAMINE |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Known human immune system toxicant | IMIDAZOLIDINYL UREA, TRIETHANOLAMINE, PAPAIN | |
| Possible human immune system toxicant | products that may be aerosolized (airborne) | MINERAL OIL |
| Possible human immune system toxicant | LINALOOL, OXYBENZONE (BENZOPHENONE-3) | |
| Human immune and respiratory toxicant - strong evidence | BROMELAIN | |
| Human skin toxicant - strong evidence | ACHILLEA MILLEFOLIUM (COMMON YARROW) EXTRACT, BUTYLPARABEN, ETHYLPARABEN, ISOBUTYLPARABEN, METHYLPARABEN, PEG-40 CASTOR OIL, PROPYLPARABEN, TOCOPHERYL ACETATE | |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human immune system toxicant - moderate evidence | products that may be aerosolized (airborne) | TANNIC ACID |
| One or more animal studies show immune effects at low doses | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more human case studies show possible immune effects | OCTISALATE, OCTINOXATE (OCTYL METHOXYCINNAMATE), HYDROLYZED WHEAT PROTEIN | |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| One or more animal studies show gastrointestinal effects at moderate doses | MICA |
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | PROPRIETARY INGREDIENTS, UNSPECIFIED EXTRACTS | |
| Occupational hazards related to handling | SODIUM HYDROXIDE |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | TITANIUM DIOXIDE (NON-NANO), PHENOXYETHANOL, TETRASODIUM EDTA | |
| Allowed workplace exposures restricted to low doses | KAOLIN, MICA | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, MINERAL OIL, TRIETHANOLAMINE | |
| No workplace limits set | GLYCOLIC ACID, LACTIC ACID, SODIUM HYDROXIDE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood | CAFFEINE, NIACINAMIDE, | |
| One or more animal studies show respiratory changes at very low doses where the human health implications are not yet well understood | products that may be aerosolized (airborne) | TITANIUM DIOXIDE (NON-NANO) |
| One or more animal studies show biochemical changes at low doses where the human health implications are not yet well understood | PHYTONADIONE | |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | ALPHA LIPOIC ACID, BETA CAROTENE, FRUCTOSE, HYDROLYZED ALGIN, TANNIC ACID | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | AESCULUS HIPPOCASTANUM (HORSE CHESTNUT) SEED EXTRACT, ARGININE, BENTONITE, CHOLESTEROL, CITRIC ACID, CYCLOMETHICONE, CYCLOPENTASILOXANE, D&C ORANGE 4, FOLIC ACID, GLYCERIN, GLYCINE, NIACIN, PANAX GINSENG (GINSENG) ROOT EXTRACT, POLYACRYLAMIDE, SODIUM BENZOATE, XYLITOL, PROPYLENE GLYCOL | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | OXYBENZONE (BENZOPHENONE-3), RETINYL PALMITATE, VITAMIN A, OCTINOXATE (OCTYL METHOXYCINNAMATE), OCTOCRYLENE | |
| Interferes with gene expresion | BUTYLPARABEN, METHYLPARABEN | |
| Does not produces excess reactive oxygen species or other harmful biochemical changes. | OCTISALATE |
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