3-METHYLBENZYLIDENE CAMPHOR
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
| Other moderate concerns for this ingredient: Persistence and bioaccumulation |
 | Lesser or emerging concerns for this ingredient: Endocrine disruption, Data gaps |
|
See products containing 3-METHYLBENZYLIDENE CAMPHOR | |
ingredient UV blocking strength
| possible* sunscreen concentrations |
UV blocking strength |
|
1.0% |
| |
2.0% |
| |
5.0% |
|
* Skin Deep does not have any concentration information for this ingredient in products. The concentrations shown are only for illustrative purposes.
3-METHYLBENZYLIDENE CAMPHOR has reported used in the following product types: (1); facial moisturizer/treatment (1)
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| One or more animal studies show effects at very low doses | Durrer S, Ehnes C, Fuetsch M et al, 2007 |
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Persistent, bioaccumulative in wildlife | OSPAR PBTs - Substances of Possible Concern | |
| Persistent, bioaccumulative in wildlife | Emerging PBTs from peer-reviewed literature | |
| show more | ||
Endocrine disruption
| type of concern | product conditions | reference |
| Associated with endocrine disruption | Durrer S, Ehnes C, Fuetsch M et al, 2007 |
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 37 studies on toxicity in PubMed see search results -> | PubMed |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Classified as not expected to be potentially toxic or harmful | Environmental Canada Domestic Substance List |
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Environmental Canada Domestic Substance List | BICYCLO[2.2.1]HEPTAN-2-ONE, 1,7,7-TRIMETHYL-3-[(4-METHYLPHENYL)METHYLENE]- | •This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for suspected bioaccumulation. |
| European Commission on Endocrine Disruption | 3-(4-METHYLBENZYLIDENE)CAMPHOR | HH-CAT1;WF-CAT3a |
| OSPAR PBTs - Substances of Possible Concern | 1,7,7-TRIMETHYL-3-[(4-METHYLPHENYL)METHYLENE]-BICYCLO(2.2.1)HEPTAN-2-ONE | •Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concern |
| Emerging PBTs from peer-reviewed literature | BICYCLO(2.2.1)HEPTAN-2-ONE, 1,7,7-TRIMETHYL-3-[(4-METHYLPHENYL)METHYLENE]- | •Persistent, bioaccumulative toxicant - Limited or emerging evidence in open scientific literature |
| Durrer S, Ehnes C, Fuetsch M et al, 2007 | 4-METHYLBENZYLIDENE CAMPHOR | 4-MBC affects development of male reproductive functions and organs, with a lowest observed adverse effect level of 0.7 mg/kg. |
| Durrer S, Ehnes C, Fuetsch M et al, 2007 | 4-METHYLBENZYLIDENE CAMPHOR | 4-MBC delays male puberty and alters hormone receptor expression in the prostate of rats. |
references
| government/industry list/academic study | reference |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| European Commission on Endocrine Disruption | EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998. |
| OSPAR PBTs - Substances of Possible Concern | OSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic. |
| Emerging PBTs from peer-reviewed literature | Emerging PBTs from peer-reviewed literature |
| Open scientific literature | Durrer S, Ehnes C, Fuetsch M et al. "Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor." Environ Health Perspect 2007; 115 Suppl 1:42-50. |
| Open scientific literature | Durrer S, Ehnes C, Fuetsch M et al. "Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor." Environ Health Perspect 2007; 115 Suppl 1:42-50. |
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