

(2,5-DIOXO-4-IMIDAZOLIDINYL) UREA; GLYOXYLDIUREID; GLYOXYLDIUREIDE; GLYOXYLIC DIUREIDE; UREA, (2,5-DIOXO-4-IMIDAZOLIDINYL) -; 5-UREIDOHYDANTOIN; (2,5-DIOXO-4-IMIDAZOLIDINYL) - UREA; UREA, (2,5DIOXO4IMIDAZOLIDINYL) ; (2,5-DIOXO-4-IMIDAZOLIDINYL) UREA; 5-UREIDOHYDANTOIN; AI3-15281


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Contamination concerns |
![]() | Lesser or emerging concerns for this ingredient: Data gaps |
|
See products containing ALLANTOIN | |
About ALLANTOIN: Allantoin is a heterocyclic organic compound. In the United States, Allantoin may be used as an active ingredient in OTC drug products. When used as an active drug ingredient, the established name is Allantoin. See "Regulatory and Ingredient Use Information," regarding the labeling names for U.S. OT C Drug Ingredients in Volume 1, Introduction, Part A.
This ingredient may be derived from animals. From PETA's Caring Consumer: Uric acid from cows, most mammals. Also in many plants (especially comfrey). In cosmetics (especially creams and lotions) and used in treatment of wounds and ulcers. Derivatives: Alcloxa, Aldioxa. Alternatives: extract of comfrey root, synthetics.
ALLANTOIN has reported used in the following product types: facial moisturizer/treatment (617); moisturizer (406); anti-aging (358); facial cleanser (261); lipstick (167); around-eye cream (160); sunscreen: SPF 15-30 (140); after shave (129); acne treatment (117); mask (113)
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 222 studies on toxicity in PubMed see search results -> | PubMed |
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
| type of concern | product conditions | reference |
| Classified as not expected to be potentially toxic or harmful | Environmental Canada Domestic Substance List |
| type of concern | product conditions | reference |
| Not suspected to be bioaccumulative | Environmental Canada Domestic Substance List | |
| show more | ||
| government/industry list/academic study | appears on list as | classification(s) |
| Environmental Canada Domestic Substance List | UREA, (2,5-DIOXO-4-IMIDAZOLIDINYL)- | •This chemical was NOT flagged by CEPA for further attention. |
| Environmental Canada Domestic Substance List | ALLANTOIN | •This chemical was NOT flagged by CEPA for further attention. |
| IFRA Fragrance Ingredient List | ALLANTOIN | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| government/industry list/academic study | reference |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
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