ALOE BARBADENSIS (ALOE VERA) GEL
Skin-Conditioning Agent - Miscellaneous; SKIN CONDITIONING
Also listed as
ALOE BARBADENSIS LEAF JUICE, ALOE BARBADENSIS GEL; ALOE GEL; ALOE JUICE; ALOE VERA GEL; CHIRUKATTALI EXTRACT
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
| Lesser or emerging concerns for this ingredient: Organ system toxicity (non-reproductive), Data gaps |
|
See products containing ALOE BARBADENSIS (ALOE VERA) GEL | |
About ALOE BARBADENSIS (ALOE VERA) GEL: Aloe Barbadensis Leaf Juice is the juice expressed from the leaves of the aloe, Aloebarbadensis. See "Regulatory and Ingredient Use Information," regarding the labeling names for botanicalingredients in Volume 1, Introduction, Part A.
ALOE BARBADENSIS (ALOE VERA) GEL has reported used in the following product types: moisturizer (585); facial moisturizer/treatment (519); facial cleanser (341); anti-aging (290); body wash/cleanser (284); hair color and bleaching (215); conditioner (193); shampoo (176); sunscreen: SPF 15-30 (162); foundation (161)
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| One or more animal studies show effects at moderate doses | CIR (2006) |
Violations, restrictions & warnings
| type of concern | product conditions | reference |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Cosmetic Ingredient Review Assessments |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | RTECS®- Indian Journal of Experimental Biology 1968 |
Data gaps
| type of concern | product conditions | reference |
| Missing safety data noted by cosmetic industry review | Cosmetic Ingredient Review Assessments | |
| 74 studies on toxicity in PubMed see search results -> | PubMed |
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| FDA Food Additive Status | ALOE | • Food additive: used in conjunction with flavors • Food additive: food additive for which a petition has been filed and a regulation issued • Food additive: must be in accordance with good manufacturing practices, or sufficient for purpose; or in quantity not greater than required • Used only in conjunction w/flavors - CFR172.510 |
| Cosmetic Ingredient Review Assessments | ALOE BARBADENSIS LEAF JUICE | •Safe for use in cosmetics with some qualifications •Industry safety panel (Cosmetic Ingredient Review, CIR) notes missing safety data in its review of this ingredient •Restrictions on impurities recommended by industry safety panel •Determined safe for use in cosmetics up to a specified concentration limit • •May contain harmful impurities |
| CIR (2006) | ALOE VERA | 3 month rat study produced significant sperm damage |
| RTECS®- Indian Journal of Experimental Biology 1968 | ALOE BARBADENSIS (ALOE VERA) GEL | • broad systemic - Broad systemic toxicity (mouse LD50) |
references
| government/industry list/academic study | reference |
| FDA Food Additive Status | FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006. |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| Open scientific literature | CIR (2006). 2006 CIR Compendium. Washington, Cosmetic Ingredient Review. |
| RTECS®- Indian Journal of Experimental Biology 1968 | RTECS®- Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 6,232,1968 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
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