AMINOMETHYL PROPANOL
pH Adjuster; BUFFERING
Also listed as
2-AMINOISOBUTANOL; 2-AMINO-2-METHYL-1-PROPANOL; 2-HYDROXYMETHYL-2-PROPYLAMINE; ISOBUTANOLAMINE; 1-PROPANOL, 2-AMINO-2-METHYL-; 2-AMINO-2-METHYL- 1-PROPANOL; 1PROPANOL, 2AMINO2METHYL; 2-AMINO-2-METHYLPROPANOL; 2-AMINO-2-METHYL-1-PROPANOL; 2-AMINO-2-METHYLPROPAN-1-OL; 2-AMINO-2-METHYLPROPANOL
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
 | Violations, restrictions & warnings |
| Allergies/immunotoxicity |
 | Contamination concerns - NITROSAMINES, OXAZOLIDINE |
 | Other strong concerns for this ingredient: Irritation (skin, eyes, or lungs) |
| Lesser or emerging concerns for this ingredient: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Ecotoxicology |
|
See products containing AMINOMETHYL PROPANOL | |
About AMINOMETHYL PROPANOL: Aminomethyl Propanol is a substituted aliphatic alcohol.
AMINOMETHYL PROPANOL has reported used in the following product types: hair spray (382); styling gel/lotion (144); hair color and bleaching (140); facial moisturizer/treatment (64); mascara (46); anti-aging (42); moisturizer (39); conditioner (28); styling mousse/foam (27); foundation (26)
Neurotoxicity
| type of concern | product conditions | reference |
| One or more animal studies show brain and nervous system effects at moderate doses | RTECS®- Journal of Industrial Hygiene and Toxicology 1940 |
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| Classified as irritant | European Union - Classification & Labelling | |
| show more | ||
Violations, restrictions & warnings
| type of concern | product conditions | reference |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Cosmetic Ingredient Review Assessments |
Endocrine disruption
| type of concern | product conditions | reference |
| One or more animal studies show endocrine system disruption at high doses | RTECS®- Journal of the American College of Toxicology 1990 |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show respiratory effects at moderate doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | RTECS®- Journal of Industrial Hygiene and Toxicology 1940 |
| show more | ||
Ecotoxicology
| type of concern | product conditions | reference |
| Wildlife and environmental toxicity | European Union - Classification & Labelling | |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| 12 studies on toxicity in PubMed see search results -> | PubMed |
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Not suspected to be bioaccumulative | Environmental Canada Domestic Substance List | |
| show more | ||
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | 2-AMINO-2-METHYLPROPANOL | •Irritant (eyes, skin, or lungs) •Irritating to eyes and skin •Harmful to aquatic organisms |
| Cosmetic Ingredient Review Assessments | AMINOMETHYL PROPANOL | •Safe for use in cosmetics with some qualifications •Determined safe for use in cosmetics up to a specified concentration limit •Amine: forms carcinogenic nitrosamine compounds if mixed with nitrosating agents •May contain harmful impurities |
| Environmental Canada Domestic Substance List | 1-PROPANOL, 2-AMINO-2-METHYL- | •This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for as a low human health priority. |
| CIR | AMINOMETHYL PROPANOL | Impurity: oxazolidine |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1940 | AMINOMETHYL PROPANOL | • brain and nervous system - Coma (rabbit LDLo) • respiratory - Respiratory stimulation (rabbit LDLo) • brain and nervous system - Somnolence (general depressed activity) (rabbit LDLo) |
| RTECS®- Journal of the American College of Toxicology 1990 | AMINOMETHYL PROPANOL | • endocrine system - Death in the "U" data type field (rat TDLo) • broad systemic - Broad systemic toxicity (mouse LD50) • skin - Hair (rat TDLo) • liver - Other changes (rat TDLo) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex I of Directive 67/548/EEC through the 31st ATP. |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| Impurities - Open Scientific Literature | CIR |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1940 | RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 22,315,1940 |
| RTECS®- Journal of the American College of Toxicology 1990 | RTECS®- Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. 9(2),203,1990 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
All rights reserved.
Favorites basket
No items in basket.
Skin Deep User Tools BETA
Looking for a product report that we don't have in Skin Deep? Sign up to enter it into the Skin Deep database and leave product reviews.
SKIN DEEP NEEDS YOUR HELP
We always want Skin Deep to be free to the public, but delivering high-quality research costs time and money. Help by donating just the cost of a bar of soap or bottle of shampoo.
WANT TO KNOW MORE?
Stay informed with email updates on toxics in everyday products and how they can affect your health.
SKIN DEEP NEWS
'I just wanted to let you know how much Skin Deep has changed my daughter's (and my) life.'
—Melissa M., Michigan