

BENZENESULFONIC ACID, 5-BENZOYL-4-HYDROXY-2-METHOXY-, MONOSODIUM SALT; 2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULFONIC ACID, SODIUM SALT; SODIUM HYDROXYMETHOXYBENZOPHENONE SULFONATE; SULISOBENZONE SODIUM; MONOSODIUM SALT BENZENESULFONIC ACID, 5-BENZOYL-4-HYDROXY-2-METHOXY-; SODIUM SALT 2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULFONIC ACID; 5-BENZOYL-4-HYDROXY-2-METHOXY- MONOSODIUM SALT BENZENESULFONIC ACID


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Contamination concerns |
![]() | Other moderate concerns for this ingredient: Irritation (skin, eyes, or lungs) |
![]() | Lesser or emerging concerns for this ingredient: Data gaps |
|
See products containing BENZOPHENONE-5 | |
About BENZOPHENONE-5: Benzophenone-5 is the sodium salt of Benzophenone-4 (q.v.).


| possible* sunscreen concentrations |
UV blocking strength![]() |
|
1.0% |
| |
5.0% |
| |
10.0% |
|
* Skin Deep does not have any concentration information for this ingredient in products. The concentrations shown are only for illustrative purposes.


BENZOPHENONE-5 has reported used in the following product types: moisturizer (2); mascara (1); anti-aging (1); facial moisturizer/treatment (1)
| type of concern | product conditions | reference |
| Human skin toxicant - strong evidence | Cosmetic Ingredient Review Assessments | |
| Human skin toxicant - strong evidence |
| type of concern | product conditions | reference |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | Japan's Standards for Cosmetics |
| type of concern | product conditions | reference |
| Human irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | Cosmetic Ingredient Review Assessments |
| type of concern | product conditions | reference |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments | |
| Safety assessment was based on related chemical | Cosmetic Ingredient Review Assessments | |
| 9 studies on toxicity in PubMed see search results -> | PubMed |
| type of concern | product conditions | reference |
| Classified as not expected to be potentially toxic or harmful | Environmental Canada Domestic Substance List |
| type of concern | product conditions | reference |
| Not suspected to be persistent | Environmental Canada Domestic Substance List | |
| show more | ||
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
| government/industry list/academic study | appears on list as | classification(s) |
| Cosmetic Ingredient Review Assessments | BENZOPHENONE-5 | •Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR) •Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product •Safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) is based on safety or product use data for a different, related ingredient •Sensitizer - can instigate immune system response that can include itching, burning, scaling, hives, and blistering of skin •Irritation (eyes, skin, or lungs) |
| Environmental Canada Domestic Substance List | BENZOPHENONE-5 | •This chemical was NOT flagged by CEPA for further attention. |
| Japan's Standards for Cosmetics | SODIUM HYDROXYMETHOXYBENZOPHENONE SULFONATE | •Japan - restricted for use in some types of cosmetics (concentration limit) |
| Japan's Standards for Cosmetics | SODIUM HYDROXYMETHOXYBENZOPHENONE SULFONATE | •Japan - restricted for use in some types of cosmetics (concentration limit) |
| Japan's Standards for Cosmetics | SODIUM HYDROXYMETHOXYBENZOPHENONE SULFONATE | •Japan - restricted for use in some types of cosmetics (concentration limit) |
| government/industry list/academic study | reference |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| Japan's Standards for Cosmetics | Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau. |
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