BHA

Antioxidant; Fragrance Ingredient; MASKING  

Also listed as

ANTIOXYNE B; ANTRANCINE 12; EEC NO. E320; EMBANOX; NIPANTIOX 1-F; PROTEX; SUSTANE 1-F; TENOX BHA


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
yes, moderateCancer
yes, weakDevelopmental/reproductive toxicity
yes, strongViolations, restrictions & warnings
yes, strongAllergies/immunotoxicity
noContamination concerns
noOther strong concerns for this ingredient:
Organ system toxicity (non-reproductive)
noOther moderate concerns for this ingredient:
Endocrine disruption, Persistence and bioaccumulation, Biochemical or cellular level changes
noLesser or emerging concerns for this ingredient:
Neurotoxicity, Ecotoxicology, Data gaps
 
See products containing BHA

About BHA: BHA is a mixture of isomers of tertiary butyl-substituted 4-methoxyphenols. It consists chieflyof 3-t-butyl-4-hydroxyanisole with lesser amounts of 2-t-butyl-4-hydroxyanisole. It conforms generally tothe formula:

BHA has reported used in the following product types: lipstick (162); eye shadow (86); facial moisturizer/treatment (57); lip liner (48); anti-aging (33); mascara (31); foundation (30); skin fading/lightener (29); lip gloss (25); eye liner (25)


Allergies/immunotoxicity

type of concern product conditions reference
Known human immune system toxicant    National Library of Medicine HazMap

Violations, restrictions & warnings

type of concern product conditions reference
Violation of government restrictions - Banned or found unsafe for use in cosmetics   EU Banned and Restricted Fragrances

Cancer

type of concern product conditions reference
Possible human carcinogen products for use on the lips  NTP Report on Carcinogens, 11th Edition
Possible human carcinogen products for use on the lips  California EPA Proposition 65
Limited evidence of carcinogenicity products for use on the lips  Int'l Agency for Research on Cancer (IARC) - Carcinogens
Possible carcinogen     Environmental Canada Domestic Substance List
show more

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Known human toxicant    EU Banned and Restricted Fragrances
Classified as a high human health priority     Environmental Canada Domestic Substance List
One or more animal studies show liver effects at very low doses    RTECS®- British Journal of Cancer 1982
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Persistence and bioaccumulation

type of concern product conditions reference
Persistent, bioaccumulative in wildlife    OSPAR PBTs - Substances of Possible Concern
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Endocrine disruption

type of concern product conditions reference
Limited evidence of endocrine disruption    Japanese National Institute of Health Sciences, 1993
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Neurotoxicity

type of concern product conditions reference
One or more animal studies show brain and nervous system effects at moderate doses    RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho 1970
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Biochemical or cellular level changes

type of concern product conditions reference
One or more animal studies show biochemical changes at very low doses where the human health implications are not yet well understood    RTECS®- British Journal of Cancer 1982
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Developmental/reproductive toxicity

type of concern product conditions reference
One or more animal studies show reproductive effects at high doses    RTECS®- Toxicology and Applied Pharmacology 2004
show more

Ecotoxicology

type of concern product conditions reference
Wildlife and environmental toxicity    Illinois EPA Chemicals Associated with Endocrine System
show more

Multiple, additive exposure sources

type of concern product conditions reference
Designated as safe for general or specific, limited use in food   FDA Food Additive Status
Designated as safe for general or specific, limited use in food   FDA Everything Added to Food

Data gaps

type of concern product conditions reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   Cosmetic Ingredient Review Assessments
1,363 studies on toxicity in PubMed see search results ->   PubMed



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
FDA Food Additive StatusBHA• AOX/FS
• GRAS (generally recognized as safe) - use in food presumed safe based either on a history of use before 1958 or on published scientific evidence; need not be approved by the FDA prior to use in food; most have not limit for use but must conform to good manufacturing practices; some GRAS substances have quantitative limit for use in foods; by definition under Sec 201(s) of FD&C Act, not food additives
• 0.02% - Of fat or oil content
• including essential (volatile) oil
• or food
• including oleomargarine - refers to part number under Title 21 Code of Federal Regulations 166
• Margarine
• Food additive: antioxidant
• Food additive: food additive for which a petition has been filed and a regulation issued
• 10 parts per million
• alone or w/BHT - In potato granules - CFR172.110
• 32 parts per million - In mixed diced
• glazed fruits - CFR172.110
• 50 parts per million
• alone
Cosmetic Ingredient Review AssessmentsBHA•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
Cosmetic Ingredient Review AssessmentsBUTYLATED HYDROXYANISOLE•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
FDA Everything Added to FoodBUTYLATED HYDROXYANISOLE• Fully up-to-date toxicology information has been sought.
Illinois EPA Chemicals Associated with Endocrine SystemTERT-BUTYLHYDROXYANISOLE•EPA: suspected endocrine disruptor
EU Banned and Restricted FragrancesBHAProhibited. Should not be used as a fragrance ingredient. Based on the depigmenting effect (pc to IFRA).
National Library of Medicine HazMapBUTYLATED HYDROXYANISOLE•Skin Sensitizer - An agent that can induce an allergic reaction in the skin or lungs: Yes;
Int'l Agency for Research on Cancer (IARC) - CarcinogensBUTYLATED HYDROXYANISOLE (BHA)•IARC Group 2B: possible human carcinogen (International Agency for Research on Carcinogens)
NTP Report on Carcinogens, 11th EditionBUTYLATED HYDROXYANISOLE (BHA)•Reasonably anticipated to be a human carcinogen (National Toxicology Program classification)
Our Stolen Future Endocrine DisruptorsBUTYLATED HYDROXYANISOLE (BHA)
OSPAR PBTs - Substances of Possible Concern(1,1DIMETHYLETHYL)4METHOXYPHENOL•Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concern
California EPA Proposition 65BUTYLATED HYDROXYANISOLE•Carcinogen: California Proposition 65
Japanese National Institute of Health Sciences, 1993BUTYLATED HYDROXYANISOLE (BHA)•Endocrine toxicity hazards: suspected
European Commission on Endocrine DisruptionTERT.-BUTYLHYDROXYANISOLE (BHA)HH-CAT1;WF-CAT1
Environmental Canada Domestic Substance ListPHENOL, (1,1-DIMETHYLETHYL)-4-METHOXY-•This chemical was deemed a high human health priority even though it did not meet the strict criteria of the categorization exercise of CEPA. The chemical was flagged for suspected carcinogenic concerns.
RTECS®- Australian Journal of Experimental Biology and Medical Science 1959BHA• liver - Changes in liver weight (rat TDLo)
RTECS®- Australian Journal of Experimental Biology and Medical Science 1961BHA• endocrine system - Changes in adrenal weight (rat TDLo)
• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo)
RTECS®- British Journal of Cancer 1982BHA• liver - Changes in liver weight (mouse TDLo)
• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (mouse TDLo)
• liver - Other changes (mouse TDLo)
RTECS®- Bulletin of Environmental Contamination and Toxicology 1985BHA• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
• liver - Other changes (rat TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 1986BHA• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Cancer Letters (Shannon, Ireland) 1999BHA• cancer - Active as anti-cancer agent (mouse TDLo)
• cancer - Protects against induction of experimental tumors (mouse TDLo)
• respiratory - Tumors (mouse TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 1999BHA• cancer - Active as anti-cancer agent (rat TDLo)
• cancer - Protects against induction of experimental tumors (rat TDLo)
• liver - Tumors (rat TDLo)
RTECS®- Cancer Letters (Shannon, Ireland) 1986BHA• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl)
RTECS®- Cancer Research 1986BHA• cancer - respiratory neoplasms (rat TD)
RTECS®- Carcinogenesis (London) 1992BHA• mutagenic - Positive mutation assay: DNA Inhibition ( human hla)
RTECS®- Carcinogenesis (London) 1983BHA• cancer - Cells (cultured) transformed (rat TD)
• cancer - kidney or renal system tumors (rat TD)
RTECS®- Carcinogenesis (London) 1992BHA• mutagenic - Positive mutation assay: DNA Inhibition ( human hla)
RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1972BHA• reproductive - Behavioral (mouse TDLo)
RTECS®- FEMS Microbiology Letters 1982BHA• mutagenic - Positive mutation assay: Mutation in Micro-organism (other micro-organisms )
RTECS®- FEMS Microbiology Letters 1982BHA• mutagenic - Positive mutation assay: Mutation in Micro-organism (other micro-organisms )
RTECS®- Food and Chemical Toxicology 1986BHA• liver - Changes in liver weight (monkey TDLo)
• gastrointestinal - Other changes (monkey TDLo)
• biochemical - Other enzymes (monkey TDLo)
RTECS®- Food and Chemical Toxicology 2004BHA• liver - Changes in liver weight (rat TDLo)
• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
• liver - Other changes (rat TDLo)
RTECS®- Food and Cosmetics Toxicology 1972BHA• liver - Changes in liver weight (monkey TDLo)
• liver - Other changes (monkey TDLo)
• biochemical - Phosphatases (monkey TDLo)
RTECS®- Food and Cosmetics Toxicology 1965BHA• liver - Changes in liver weight (rat TDLo)
• biochemical - Phosphatases (rat TDLo)
RTECS®- Gann 1982BHA• cancer - gastrointestinal tumor formations - equivocal (rat TD)
• cancer - gastrointestinal tumors (rat TDLo)
RTECS®- Gann 1983BHA• cancer - gastrointestinal neoplasms (hamster TD)
RTECS®- Japanese Journal of Cancer Research 1986BHA• cancer - gastrointestinal tumor formations - equivocal (mouse TDLo)
• cancer - gastrointestinal tumors (hamster TDLo)
RTECS®- Japanese Journal of Cancer Research 1986BHA• cancer - gastrointestinal neoplasms (rat TD)
RTECS®- Japanese Journal of Cancer Research 1993BHA• mutagenic - endocrine system tumors (rat TD)
• cancer - gastrointestinal tumors (rat TD)
RTECS®- Journal of the American Oil Chemists' Society 1977BHA• broad systemic - Broad systemic toxicity (rabbit LD50)
RTECS®- Journal of the National Cancer Institute 1977BHA• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster fbr)
RTECS®- Journal of the National Cancer Institute 1977BHA• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster fbr)
RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho 1970BHA• brain and nervous system - Altered sleep time (including change in righting reflex) (mouse LD50)
• brain and nervous system - Ataxia (mouse LD50)
• liver - Changes in liver weight (rat TDLo)
• blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo)
• endocrine system - Changes in thyroid weight (rat TDLo)
• respiratory - Respiratory stimulation (mouse LD50)
RTECS®- Mutation Research 1996BHA• mutagenic - Positive mutation assay: DNA Damage (rat lvr)
RTECS®- Mutation Research 2002BHA• mutagenic - Positive mutation assay: DNA Damage (mouse orl)
RTECS®- Mutation Research 1996BHA• mutagenic - Positive mutation assay: DNA Damage (rat lvr)
RTECS®- Mutation Research 2002BHA• mutagenic - Positive mutation assay: DNA Damage (mouse orl)
RTECS®- Neurobehavioral Toxicology and Teratology 1981BHA• reproductive - Growth statistics (rat TDLo)
• reproductive - Weaning or lactation index (rat TDLo)
RTECS®- Toxicology and Applied Pharmacology 2004BHA• reproductive - Uterus, cervix, vagina (rat TDLo)
• endocrine system - Changes in adrenal weight (rat TDLo)
• liver - Changes in liver weight (rat TDLo)
• endocrine system - Changes in prostate weight (rat TDLo)
• endocrine system - Changes in uterine weight (rat TDLo)
RTECS®- Toxicology In Vitro 1991BHA• mutagenic - Positive mutation assay: DNA Inhibition (hamster lng)
RTECS®- Toxicology In Vitro 1991BHA• mutagenic - Positive mutation assay: DNA Inhibition (hamster lng)
RTECS®- Toxicology Letters 2003BHA• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
• biochemical - Other transferases (rat TDLo)
RTECS®- Toxicology Letters 1985BHA• blood - Hemorrhage (rat LD50)
• metabolic - Weight loss or decreased weight gain (rat TDLo)
• respiratory - Changes in lung weight (rat TDLo)
• blood - Other hemolysis with or without anemia (rat TDLo)
RTECS®- Toxicology Letters 1986BHA• cancer - gastrointestinal tumors (rat TD)
RTECS®- Toxicology 2005BHA• developmental - Delayed effects (rat TDLo)
• reproductive - Mating performance (rat TDLo)
• reproductive - Other effects in male (rat TDLo)

references

government/industry list/academic study reference
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Illinois EPA Chemicals Associated with Endocrine SystemIllinois EPA (Illinois Environmental Protection Agency). 2000. Preliminary list of chemicals associated with endocrine system effects in animals and humans (*) or in vitro (+). In EPA (U.S. Environmental Protection Agency) 2000. Handbook for Non-Cancer Health Effects Valuation, Appendix C.
EU Banned and Restricted FragrancesSCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 1999. Opinion Concerning Fragrance Allergy In Consumers. . SCCNFP/0017/98 Final, December 1999; and SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 2000. An Initial List Of Perfumery Materials Which Must Not Form Part Of Fragrances Compounds Used In Cosmetic Products. SCCNFP/0320/00, final May 2000.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
NTP Report on Carcinogens, 11th EditionNTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
Our Stolen Future Endocrine DisruptorsColborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
OSPAR PBTs - Substances of Possible ConcernOSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
California EPA Proposition 65California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
Scorecard.org Toxicity InformationJapanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, World Wildlife Fund. Our Stolen Future. Widespread Pollutants with Endocrine-disrupting Effects. http://www.ourstolenfuture.org/Basics/chemlist.htm. The WWF list is derived from references detailed at http://www.ourstolenfuture.org/Sources/chemsources.htm and was originally published in: Colborn, T., F.S. vom Saal, and A.M. Soto. Developmental Effects of Endocrine-Disrupting Chemicals In Wildlife and Humans. Environmental Health Perspectives 101(5): 378-384. 1993.
European Commission on Endocrine DisruptionEU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
Environmental Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS®- Australian Journal of Experimental Biology and Medical Science 1959RTECS®- Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. 37,533,1959
RTECS®- Australian Journal of Experimental Biology and Medical Science 1961RTECS®- Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. 39,353,1961
RTECS®- British Journal of Cancer 1982RTECS®- British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- 45,935,1982
RTECS®- Bulletin of Environmental Contamination and Toxicology 1985RTECS®- Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- 34,787,1985
RTECS®- Cancer Letters (Shannon, Ireland) 1986RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 33,119,1986
RTECS®- Cancer Letters (Shannon, Ireland) 1999RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 137,123,1999
RTECS®- Cancer Letters (Shannon, Ireland) 1999RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 143,173,1999
RTECS®- Cancer Letters (Shannon, Ireland) 1986RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 33,119,1986
RTECS®- Cancer Research 1986RTECS®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- 46,165,1986
RTECS®- Carcinogenesis (London) 1992RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- 13,2389,1992
RTECS®- Carcinogenesis (London) 1983RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- 4,895,1983
RTECS®- Carcinogenesis (London) 1992RTECS®- Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 13,2389,1992
RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology 1972RTECS®- Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. 31,596,1972
RTECS®- FEMS Microbiology Letters 1982RTECS®- FEMS Microbiology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 14,183,1982
RTECS®- FEMS Microbiology Letters 1982RTECS®- FEMS Microbiology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 14,183,1982
RTECS®- Food and Chemical Toxicology 1986RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 24,1197,1986
RTECS®- Food and Chemical Toxicology 2004RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 42,899,2004
RTECS®- Food and Cosmetics Toxicology 1972RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 10,769,1972
RTECS®- Food and Cosmetics Toxicology 1965RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 3,457,1965
RTECS®- Gann 1982RTECS®- Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. 73,332,1982
RTECS®- Gann 1983RTECS®- Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. 74,459,1983
RTECS®- Japanese Journal of Cancer Research 1986RTECS®- Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- 77,1083,1986
RTECS®- Japanese Journal of Cancer Research 1986RTECS®- Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- 77,854,1986
RTECS®- Japanese Journal of Cancer Research 1993RTECS®- Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- 84,237,1993
RTECS®- Journal of the American Oil Chemists' Society 1977RTECS®- Journal of the American Oil Chemists' Society. (Champaign, IL) V.24-56, 1947-79. 54,239,1977
RTECS®- Journal of the National Cancer Institute 1977RTECS®- Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. 58,1635,1977
RTECS®- Journal of the National Cancer Institute 1977RTECS®- Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. 58,1635,1977
RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho 1970RTECS®- Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50- 22,231,1970
RTECS®- Mutation Research 1996RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 368,59,1996
RTECS®- Mutation Research 2002RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 519,103,2002
RTECS®- Mutation Research 1996RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 368,59,1996
RTECS®- Mutation Research 2002RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 519,103,2002
RTECS®- Neurobehavioral Toxicology and Teratology 1981RTECS®- Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. 3,321,1981
RTECS®- Toxicology and Applied Pharmacology 2004RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 197,230,2004
RTECS®- Toxicology In Vitro 1991RTECS®- Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 5,549,1991
RTECS®- Toxicology In Vitro 1991RTECS®- Toxicology In Vitro. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- 5,549,1991
RTECS®- Toxicology Letters 2003RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 145,281,2003
RTECS®- Toxicology Letters 1985RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 27,15,1985
RTECS®- Toxicology Letters 1986RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 31(Suppl),207,1986
RTECS®- Toxicology 2005RTECS®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 208,49,2005

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.

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