

CITRUS GRANDIS SEED EXTRACT; CITRUS PARADISI SEED EXTRACT; EXTRACT OF CITRUS GRANDIS SEED; EXTRACT OF GRAPEFRUIT SEED; EXTRACT OF GRAPEFRUIT SEEDS; GRAPEFRUIT SEED EXTRACT; GRAPEFRUIT SEEDS EXTRACT; CITRUS SEED EXTRACT; GRAPEFRUIT, EXT.


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Contamination concerns - BENZETHONIUM CHLORIDE, METHYLPARABEN, TRICLOSAN |
![]() | Other strong concerns for this ingredient: Multiple, additive exposure sources |
![]() | Lesser or emerging concerns for this ingredient: Data gaps |
|
See products containing CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT | |
About CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT: Citrus Grandis (Grapefruit) Seed Extract is an extract of the seeds of the grapefruit, Citrusgrandis. See "Regulatory and Ingredient Use Information," regarding the labeling names for botanicalingredients in Volume 1, Introduction, Part A.
CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT has reported used in the following product types: moisturizer (113); facial moisturizer/treatment (107); facial cleanser (58); shampoo (55); conditioner (53); anti-aging (39); body wash/cleanser (39); hand cream (33); exfoliant/scrub (30); bar soap (29)
| type of concern | product conditions | reference |
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 24 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed |
| government/industry list/academic study | appears on list as | classification(s) |
| FDA Everything Added to Food | GRAPEFRUIT, EXTRACT | • There is reported use of the substance, but it has not yet been assigned for toxicology literature search. |
| von Woedtke T, Schluter B, Pflegel P, Lindequist U, Julich WD, 1999 | GRAPEFRUIT SEED EXTRACT | In all of the antimicrobial active grapefruit seed extracts, the preservative benzethonium chloride was detected by thin layer chromatography. Additionally, three extracts contained the preserving substances triclosan and methyl paraben. |
| IFRA Fragrance Ingredient List | GRAPEFRUIT OIL, EXPRESSED (CITRUS PARADISI MACF.) | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| government/industry list/academic study | reference |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Open scientific literature | von Woedtke T, Schluter B, Pflegel P, Lindequist U, Julich WD. Aspects of the antimicrobial efficacy of grapefruit seed extract and its relation to preservative substances contained. Pharmazie. 1999 Jun;54(6):452-6. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
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