CYCLOMETHICONE
ANTISTATIC; EMOLLIENT; HAIR CONDITIONING; HUMECTANT; SOLVENT; VISCOSITY CONTROLLING
Also listed as
CYCLOPENTASILOXANE, DECAMETHYL; CYCLIC DIMETHYLSILOXANE PENTAMER; CYCLOPOLYDIMETHYLSILOXANE; DECAMETHYLCYCLOPENTASILOXANE; DEKAMETHYLCYKLOPENTASILOXAN (CZECH) ; DIMETHYLCYCLOPOLYSILOXANE; DIMETHYLSILOXANE PENTAMER; DOW CORNING 344; DOW CORNING 344 FLUID; DOW CORNING 345; DOW CORNING 345 FLUID
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
 | Other moderate concerns for this ingredient: Persistence and bioaccumulation, Organ system toxicity (non-reproductive) |
 | Lesser or emerging concerns for this ingredient: Irritation (skin, eyes, or lungs), Data gaps, Biochemical or cellular level changes |
|
See products containing CYCLOMETHICONE | |
CYCLOMETHICONE has reported used in the following product types: facial moisturizer/treatment (527); foundation (431); moisturizer (370); anti-aging (365); sunscreen: makeup (277); sunscreen: SPF 15-30 (208); conditioner (166); concealer (152); antiperspirant/deodorant (147); hair color and bleaching (136)
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environmental Canada Domestic Substance List | |
| Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | |
| show more | ||
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Classified as expected to be toxic or harmful | Environmental Canada Domestic Substance List | |
| Classified as medium human health priority | Environmental Canada Domestic Substance List | |
| show more | ||
Biochemical or cellular level changes
| type of concern | product conditions | reference |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | RTECS®- National Technical Information Service 0101 |
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| One or more animal studies show skin irritation at moderate doses | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 |
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Data gaps
| type of concern | product conditions | reference |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments | |
| 26 studies on toxicity in PubMed see search results -> | PubMed |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Cosmetic Ingredient Review Assessments | CYCLOMETHICONE | •Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR) •Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product |
| Environmental Canada Domestic Substance List | CYCLOSILOXANES, DI-ME | •This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. The chemical was flagged for suspected persistence and aquatic toxicity. |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | CYCLOSILOXANES, DIME | •Suspected persistent, bioaccumulative toxicant - Environment Canada, July 2006 chemical inventory review |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | CYCLOMETHICONE | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
| RTECS®- National Technical Information Service 0101 | CYCLOMETHICONE | • liver - Changes in liver weight (rat TDLo) • biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo) • liver - Other changes (rat TDLo) |
references
| government/industry list/academic study | reference |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,1234,1986 |
| RTECS®- National Technical Information Service 0101 | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0590101 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
All rights reserved.
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