DIPOTASSIUM GLYCYRRHIZATE

Flavoring Agent; Skin-Conditioning Agent - Miscellaneous; HUMECTANT; SKIN CONDITIONING  

Also listed as

DIPOTASSIUM GLYCYRRHIZINATE; (3B,20B ) -20-CARBOXY-11-OXO-30-NORLEAN-12-EN-3-YL-2-O-B -D-GLUCOPYRANURONOSYL-, DIPOTASSIUM SALT; 30-NOROLEANANE,A -D-GLUCOPYRANOSIDURONIC ACID DERIV.; DIPOTASSIUM SALT (3B,20B ) -20-CARBOXY-11-OXO-30-NORLEAN-12-EN-3-YL-2-O-B -D-GLUCOPYRANURONOSYL-


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
noCancer
noDevelopmental/reproductive toxicity
yes, weakViolations, restrictions & warnings
noAllergies/immunotoxicity
noContamination concerns
noLesser or emerging concerns for this ingredient:
Data gaps
 
See products containing DIPOTASSIUM GLYCYRRHIZATE

About DIPOTASSIUM GLYCYRRHIZATE: Dipotassium Glycyrrhizate is the dipotassium salt of Glycyrrhizic Acid (q.v.).

DIPOTASSIUM GLYCYRRHIZATE has reported used in the following product types: facial moisturizer/treatment (66); anti-aging (46); facial cleanser (27); acne treatment (27); sunscreen: SPF greater than 30 (25); foundation (22); around-eye cream (17); skin fading/lightener (13); mask (13); sunscreen: makeup (12)


Violations, restrictions & warnings

type of concern product conditions reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Restrictions on impurities recommended by industry safety panel   Cosmetic Ingredient Review Assessments

Data gaps

type of concern product conditions reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   Cosmetic Ingredient Review Assessments
Considered safe based on assumption of low absorption   Cosmetic Ingredient Review Assessments
8 studies on toxicity in PubMed see search results ->   PubMed



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Cosmetic Ingredient Review AssessmentsDIPOTASSIUM GLYCYRRHIZATE•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
•Restrictions on impurities recommended by industry safety panel
•May contain harmful impurities
•Determined safe for use in cosmetics based on assumption of low absorption through skin

references

government/industry list/academic study reference
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.

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