DISODIUM COCOAMPHODIACETATE

Hair Conditioning Agent; Surfactant - Cleansing Agent; Surfactant - Foam Booster;Surfactant - Hydrotrope; FOAM BOOSTING; SKIN CONDITIONING  

SCORE

1

low hazard

 

87%

data gap

(why scores have changed)

Also listed as

COCOAMPHOCARBOXYGLYCINATE; COCOAMPHODIACETATE; DISODIUM N-COCOYL-N-CARBOXYMETHOXYETHYL-N-CARBOXYMETHYLETHYLENEDIAMINE; IMIDAZOLIUM COMPOUNDS, 1 [2 (CARBOXYMETHOXY) ETHYL] 1 (CARBOXYMETHYL) 4,5DIHYDRO2NORCOCO ALKYL, HYDROXIDES, INNER SALTS, DISODIUM SALTS; IMIDAZOLIUM COMPOUNDS, 1- [2- (CARBOXYMETHOXY) ETHYL] -1- (CARBOXYMETHYL) -4,5-DIHYDRO-2-NORCOCO ALKYL, HYDROXIDES, SODIUM SALTS; ALKATERIC 2CIB; AMPHOLAK XCO 30; AMPHOTERIC 2; MACKAM 2C; MIRANOL C 2M CONC.; MIRANOL C 2M-NP-HV


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
noCancer
noDevelopmental/reproductive toxicity
noViolations, restrictions & warnings
noAllergies/immunotoxicity
noContamination concerns
noOther moderate concerns for this ingredient:
Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
noLesser or emerging concerns for this ingredient:
Data gaps
 
See products containing DISODIUM COCOAMPHODIACETATE

About DISODIUM COCOAMPHODIACETATE: Disodium Cocoamphodiacetate is the amphoteric organic compound that conforms generallyto the formula: where RCO- represents the fatty acids derived from coconut oil.

DISODIUM COCOAMPHODIACETATE has reported used in the following product types: shampoo (151); facial cleanser (97); body wash/cleanser (87); baby wipes (35); acne treatment (33); exfoliant/scrub (33); eye makeup remover (29); mascara (22); personal cleansing (21); makeup remover (19)


Organ system toxicity (non-reproductive)

type of concern product conditions reference
One or more animal studies show sense organ effects at very low doses products for use around the eyes, mouth, or lips  RTECS®- National Technical Information Service 6642
show more

Irritation (skin, eyes, or lungs)

type of concern product conditions reference
One or more animal studies show skin irritation at very low doses    RTECS®- National Technical Information Service 0065

Data gaps

type of concern product conditions reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product   Cosmetic Ingredient Review Assessments
1 studies on toxicity in PubMed see search results ->   PubMed

Ecotoxicology

type of concern product conditions reference
Not suspected to be an environmental toxin     Environmental Canada Domestic Substance List

Persistence and bioaccumulation

type of concern product conditions reference
Not suspected to be persistent     Environmental Canada Domestic Substance List
show more



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Cosmetic Ingredient Review AssessmentsCOCOAMPHODIACETATE•Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR)
•Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product
Environmental Canada Domestic Substance ListIMIDAZOLIUM COMPOUNDS, 1-[2-(CARBOXYMETHOXY)ETHYL] -1-(CARBOXYMETHYL)-4,5-DIHYDRO-2-NORCOCO ALKYL, HYDROXIDES, INNER SALTS, DISODIUM SALTS•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for as a low human health priority.
RTECS®- National Technical Information Service 6642DISODIUM COCOAMPHODIACETATE• sense organ - Primary eye irritant (rabbit )
RTECS®- National Technical Information Service 0065DISODIUM COCOAMPHODIACETATE• skin - Primary skin irritant (rabbit )
RTECS®- National Technical Information Service 6642DISODIUM COCOAMPHODIACETATE• sense organ - Primary eye irritant (rabbit )
RTECS®- National Technical Information Service 0065DISODIUM COCOAMPHODIACETATE• skin - Primary skin irritant (rabbit )

references

government/industry list/academic study reference
Cosmetic Ingredient Review AssessmentsCIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
Environmental Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS®- National Technical Information Service 6642RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0536642
RTECS®- National Technical Information Service 0065RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0590065
RTECS®- National Technical Information Service 6642RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0536642
RTECS®- National Technical Information Service 0065RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0590065

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.

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