ETHYLACRYLATE
PLASTICISER
Also listed as
2PROPENOIC ACID, ETHYL ESTER; 2-PROPANOIC ACID, ETHYL ESTER; 2-PROPENOIC ACID, ETHYL ESTER; ACRYLATE D'ETHYLE (FRENCH) ; ACRYLSAEUREAETHYLESTER (GERMAN) ; AETHYLACRYLAT (GERMAN) ; AKRYLANEM ETYLU (POLISH) ; CARBOSET 511; ETHOXYCARBONYLETHYLENE; ETHYL 2-PROPENOATE; ETHYL ACRYLATE
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
 | Violations, restrictions & warnings |
| Allergies/immunotoxicity |
 | Contamination concerns |
| Other strong concerns for this ingredient: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
 | Lesser or emerging concerns for this ingredient: Neurotoxicity, Ecotoxicology, Data gaps |
|
See products containing ETHYLACRYLATE | |
ETHYLACRYLATE has reported used in the following product types: mascara (1)
Allergies/immunotoxicity
| type of concern | product conditions | reference |
| Known human immune system toxicant | National Library of Medicine HazMap | |
| Limited evidence of immune system toxicity | products for use on skin | European Union - Classification & Labelling |
| Limited evidence of immune system toxicity | European Economic Community, 1987 |
Violations, restrictions & warnings
| type of concern | product conditions | reference |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | European Union - Banned or Restricted in Cosmetics | |
| Violation of industry recommendations - Unsafe for use in cosmetics | International Fragrance Association Codes & Standards |
Cancer
| type of concern | product conditions | reference |
| Possible human carcinogen | California EPA Proposition 65 | |
| Limited evidence of carcinogenicity | Int'l Agency for Research on Cancer (IARC) - Carcinogens | |
| Limited evidence of carcinogenicity | NIOSH Occupational Carcinogens | |
| show more | ||
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Known human respiratory toxicant | EPA Hazardous Air Pollutants | |
| Classified as expected to be toxic or harmful | Environmental Canada Domestic Substance List | |
| show more | ||
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| Limited evidence of developmental toxicity | US EPA, 9204 | |
| show more | ||
Occupational hazards
| type of concern | product conditions | reference |
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling | |
| Allowed workplace exposures restricted to moderate doses | RTECS®- TLV/BEI,2006 | |
| Allowed workplace exposures restricted to moderate doses | RTECS®- TLV/BEI,2007 | |
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Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| Classified as irritant | European Union - Classification & Labelling | |
| Human skin irritant - moderate evidence | National Library of Medicine HazMap | |
| show more | ||
Neurotoxicity
| type of concern | product conditions | reference |
| One or more animal studies show brain and nervous system effects at high doses | RTECS®- Toxicology and Applied Pharmacology 1964 |
Ecotoxicology
| type of concern | product conditions | reference |
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environmental Canada Domestic Substance List | |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 142 studies on toxicity in PubMed see search results -> | PubMed |
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Miscellaneous
| type of concern | product conditions | reference |
| Occupational hazards related to handling | European Union - Classification & Labelling |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | ETHYL ACRYLATE | •Highly flammable •Highly flammable •Harmful •Harmful by inhalation, in contact with skin and if swallowed •Irritant (eyes, skin, or lungs) •Irritating to eyes, respiratory system and skin •May cause sensitization by skin contact |
| FDA Everything Added to Food | ETHYL ACRYLATE | • Fully up-to-date toxicology information has been sought. |
| European Union - Banned or Restricted in Cosmetics | ETHYL ACRYLATE, WHEN USED AS A FRAGRANCE INGREDIENT. | •Prohibited in EU cosmetics: must not form part of the composition of cosmetic products |
| EPA Hazardous Air Pollutants | ETHYL ACRYLATE | •Hazardous air pollutant under Clean Air Act |
| National Library of Medicine HazMap | ETHYL ACRYLATE | •Skin Sensitizer - An agent that can induce an allergic reaction in the skin or lungs: Yes; •Dermatotoxin: Skin Burns; •Toxic Pneumonitis: Yes; •PEL (OSHA) - Permissible exposure limit (OSHA): 25 ppm; •STEL (ACGIH) - Short-term exposure limits (ACGIH): 15 ppm; •RD50 - Concentration producing a 50% decrease in respiratory rate in experimental animals following a 10-minute exposure: 315 ppm; •LC50 - Lethal concentration in 50% of animals tested: 4360 ppm; •IARC Carcinogen - International Agency for Research on Cancer; classifies chemicals as established (1), probable (2a), or possible (2b) human carcinogens: Possible Carcinogen; •TLV (ACGIH) - Threshold limit value (ACGIH): 5 ppm; •Flammability (NFPA) - NFPA flammability code: 0 = will not burn; 1 = must be preheated; 2 = high ambient temp required; 3 = may ignite at ambient temp; 4 = burn readily: 3: may ignite at ambient temperature; •IDLH (NIOSH) - Immediately Dangerous to Life or Health: 300 ppm; •Lacrimator - A substance that irritates the eyes and induces the flow of tears: Yes; •Odor Threshold High - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 0.0013 ppm; •Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 0.0002 ppm; •MAK - Maximum Allowable Concentration (Federal Republic of Germany): 5 ppm; |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | ETHYL ACRYLATE | •IARC Group 2B: possible human carcinogen (International Agency for Research on Carcinogens) |
| International Fragrance Association Codes & Standards | ETHYL ACRYLATE | •Fragrance unsafe for use in cosmetics |
| EPA Categorized List of Inert Pesticide Ingredients | ETHYL ACRYLATE | •Pesticide inerts of toxicological concern according to EPA (Environmental Protection Agency) |
| NIOSH Occupational Carcinogens | ETHYL ACRYLATE | •Potential occupational carcinogen according to NIOSH (National Institute for Occupational Safety and Health) |
| EPA Toxic Release Inventory PBTs | ETHYL ESTER2PROPENOIC ACID | •Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programs |
| California EPA Proposition 65 | ETHYL ACRYLATE | •Carcinogen: California Proposition 65 |
| European Economic Community, 1992 | ETHYL ACRYLATE | •Skin or sense organ toxicity hazards: suspected |
| European Economic Community, 1987 | ETHYL ACRYLATE | •Immunotoxicity hazards: suspected |
| US EPA, Air Risk Information Support Center | ETHYL ACRYLATE | •Respiratory toxicity hazards: suspected |
| US EPA, Air Risk Information Support Center | ETHYL ACRYLATE | •Gastrointestinal or liver toxicity hazards: suspected |
| US EPA, 9204 | ETHYL ACRYLATE | •Developmental toxicity hazards: suspected |
| Environmental Canada Domestic Substance List | 2-PROPENOIC ACID, ETHYL ESTER | •This chemical was deemed a high human health priority and was flagged by CEPA for further attention. The chemical is suspected to be carcinogenic. |
| EU Banned and Restricted Fragrances | ETHYL ACRYLATE | |
| Association of Occupational and Environmental Clinics | ETHYL ACRYLATE | • o |
| RTECS®- TLV/BEI,2006 | ETHYLACRYLATE | • occupationally related - ACGIH TLV (human TWA) |
| RTECS®- TLV/BEI,2007 | ETHYLACRYLATE | • occupationally related - ACGIH TLV (human TWA) |
| RTECS®- Environmental Mutagenesis 1983 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
| RTECS®- Environmental Mutagenesis 1986 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym) • mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse lym) • mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells (mouse lym) |
| RTECS®- Gann Monograph on Cancer Research 1981 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng) |
| RTECS®- Gann Monograph on Cancer Research 1981 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng) |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1949 | ETHYLACRYLATE | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1949 | ETHYLACRYLATE | • sense organ - Primary eye irritant (rat ) |
| RTECS®- MSHA STANDARD-air: 3,102,1971 | ETHYLACRYLATE | • occupationally related - MSHA STANDARD-air (human TWA) |
| RTECS®- Mutation Research 1984 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Micronucleus test (mouse ipr) |
| RTECS®- Mutation Research 1984 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Micronucleus test (mouse ipr) |
| RTECS®- National Technical Information Service 0988 | ETHYLACRYLATE | • gastrointestinal - Other changes (rat TDLo) |
| RTECS®- National Technical Information Service 7583 | ETHYLACRYLATE | • reproductive - Other effects (rat TDLo) |
| RTECS®- National Technical Information Service | ETHYLACRYLATE | • cancer - gastrointestinal tumors (rat TDLo) |
| RTECS®- National Toxicology Program Technical Report Series 1986 | ETHYLACRYLATE | • cancer - gastrointestinal tumors (rat TDLo) • gastrointestinal - Ulceration or bleeding from stomach (rat TDLo) |
| RTECS®- OSHA PEL (Construc): 29,1926 1994 | ETHYLACRYLATE | • occupationally related - OSHA PEL (Construc) (human TWA) |
| RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994 | ETHYLACRYLATE | • occupationally related - OSHA PEL (Fed Cont) (human TWA) |
| RTECS®- OSHA PEL (Gen Indu): 29,1910 1994 | ETHYLACRYLATE | • occupationally related - OSHA PEL (Gen Indu) (human TWA) |
| RTECS®- OSHA PEL (Shipyard): 29,1915 1993 | ETHYLACRYLATE | • occupationally related - OSHA PEL (Shipyard) (human TWA) |
| RTECS®- Science 1987 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr) • mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr) |
| RTECS®- Science 1987 | ETHYLACRYLATE | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr) • mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr) |
| RTECS®- Toxicology and Applied Pharmacology 1964 | ETHYLACRYLATE | • metabolic - Weight loss or decreased weight gain (rat TDLo) • brain and nervous system - Fluid intake (rat TDLo) • brain and nervous system - Food intake (animal) (rat TDLo) |
| RTECS®- Toxicology and Applied Pharmacology 1985 | ETHYLACRYLATE | • gastrointestinal - Other changes (rat TDLo) • gastrointestinal - Ulceration or bleeding from stomach (rat TDLo) |
| RTECS®- Union Carbide Data Sheet 1971 | ETHYLACRYLATE | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex I of Directive 67/548/EEC through the 31st ATP. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| European Union - Banned or Restricted in Cosmetics | EC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation." |
| EPA Hazardous Air Pollutants | EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005. |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| Int'l Agency for Research on Cancer (IARC) - Carcinogens | IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
| International Fragrance Association Codes & Standards | IFRA (International Fragrance Association). 2006. Codes and Standards. |
| EPA Categorized List of Inert Pesticide Ingredients | EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients. |
| NIOSH Occupational Carcinogens | NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html. |
| EPA Toxic Release Inventory PBTs | EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
| California EPA Proposition 65 | California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity. |
| Scorecard.org Toxicity Information | European Economic Community. Sensitizing Substances in the EEC List of Dangerous Substances. Annex I to Council Directive 67/548/EEC. http://www.kemi.se/default_eng.cfm?page=klass_mark/klasshem_eng.htm, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, Lock, E.A., and E. Harpur. Toxicology of Sensory System: A Perspective. Human and Experimental Toxicology. 11(6): 442-448. 1992. (Table 1: Chemicals that induce olfactory lesions in experimental animals by either inhalation and/or non-inhalation routes)., National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | European Economic Community. Sensitizing Substances in the EEC List of Dangerous Substances. Annex I to Council Directive 67/548/EEC. http://www.kemi.se/default_eng.cfm?page=klass_mark/klasshem_eng.htm, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, Swedish National Chemicals Inspectorate. Labelling of chemical products, Swedish regulations and general advice with regard to the classification and labelling of chemical products hazardous to health, flammables and explosives. List of Allergenic Substances. National Chemicals Inspectorate, Solna, Sweden. 1987, 1990-1992. |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html, National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation. |
| Scorecard.org Toxicity Information | US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EU Banned and Restricted Fragrances | SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 1999. Opinion Concerning Fragrance Allergy In Consumers. . SCCNFP/0017/98 Final, December 1999; and SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 2000. An Initial List Of Perfumery Materials Which Must Not Form Part Of Fragrances Compounds Used In Cosmetic Products. SCCNFP/0320/00, final May 2000. |
| Association of Occupational and Environmental Clinics | AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation. |
| RTECS®- TLV/BEI,2006 | RTECS®- TLV/BEI,2006 |
| RTECS®- TLV/BEI,2007 | RTECS®- TLV/BEI,2007 |
| RTECS®- Environmental Mutagenesis 1983 | RTECS®- Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. 5(Suppl 1),3,1983 |
| RTECS®- Environmental Mutagenesis 1986 | RTECS®- Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. 8(Suppl 6),4,1986 |
| RTECS®- Gann Monograph on Cancer Research 1981 | RTECS®- Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- 27,95,1981 |
| RTECS®- Gann Monograph on Cancer Research 1981 | RTECS®- Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 27,95,1981 |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1949 | RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 31,311,1949 |
| RTECS®- Journal of Industrial Hygiene and Toxicology 1949 | RTECS®- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. 31,317,1949 |
| RTECS®- MSHA STANDARD-air: 3,102,1971 | RTECS®- MSHA STANDARD-air: 3,102,1971 |
| RTECS®- Mutation Research 1984 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 135,189,1984 |
| RTECS®- Mutation Research 1984 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 135,189,1984 |
| RTECS®- National Technical Information Service 0988 | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0540988 |
| RTECS®- National Technical Information Service 7583 | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0557583 |
| RTECS®- National Technical Information Service | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB87-204061/AS |
| RTECS®- National Toxicology Program Technical Report Series 1986 | RTECS®- National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- NTP-TR-259,1986 |
| RTECS®- OSHA PEL (Construc): 29,1926 1994 | RTECS®- OSHA PEL (Construc): 29,1926.55,1994 |
| RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994 | RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994 |
| RTECS®- OSHA PEL (Gen Indu): 29,1910 1994 | RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994 |
| RTECS®- OSHA PEL (Shipyard): 29,1915 1993 | RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993 |
| RTECS®- Science 1987 | RTECS®- Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- 236,933,1987 |
| RTECS®- Science 1987 | RTECS®- Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 236,933,1987 |
| RTECS®- Toxicology and Applied Pharmacology 1964 | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 6,29,1964 |
| RTECS®- Toxicology and Applied Pharmacology 1985 | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 80,323,1985 |
| RTECS®- Union Carbide Data Sheet 1971 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 12/14/1971 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
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