PANTHENOL
Hair Conditioning Agent; ANTISTATIC; SKIN CONDITIONING
Also listed as
DEXPANTHENOL; PANTOTHENOL; PANTOTHENYL ALCOHOL; D-PANTOTHENYL ALCOHOL; DL-PANTOTHENYL ALCOHOL; PROVITAMIN B5; PANTHENOL , DL-FORM; (+-) -PANTOTHENYL ALCOHOL; ALCOOL DL-PANTOTENILICO (ITALIAN) ; DL-PANTOTHENYL ALCOHOL; PANTENOL
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
 | Other strong concerns for this ingredient: Multiple, additive exposure sources |
 | Lesser or emerging concerns for this ingredient: Organ system toxicity (non-reproductive), Data gaps |
|
See products containing PANTHENOL | |
About PANTHENOL: Panthenol is the alcohol.
This ingredient may be derived from animals. From PETA's Caring Consumer: Can come from animal or plant sources or synthetics. In shampoos, supplements, emollients, etc. In foods. Derivative: Panthenyl. Alternatives: synthetics, plants.
PANTHENOL has reported used in the following product types: conditioner (928); facial moisturizer/treatment (901); hair color and bleaching (839); shampoo (784); mascara (735); anti-aging (548); moisturizer (511); styling gel/lotion (452); facial cleanser (376); foundation (329)
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | RTECS®- Farmaco, Edizione Scientifica 1959 | |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments | |
| 68 studies on toxicity in PubMed see search results -> | PubMed |
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Not suspected to be persistent | Environmental Canada Domestic Substance List | |
| show more | ||
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Cosmetic Ingredient Review Assessments | PANTHENOL | •Safe as used in cosmetics according to industry panel (Cosmetic Ingredient Review, CIR) •Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product |
| FDA Everything Added to Food | D-PANTOTHENYL ALCOHOL | • There is no reported use of the substance and there is no toxicology information available in PAFA. |
| Environmental Canada Domestic Substance List | BUTANAMIDE, 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL-, (±)- | •This chemical was NOT flagged by CEPA for further attention. |
| RTECS®- Farmaco, Edizione Scientifica 1959 | PANTHENOL | • broad systemic - Broad systemic toxicity (mouse LD50) |
references
| government/industry list/academic study | reference |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| RTECS®- Farmaco, Edizione Scientifica 1959 | RTECS®- Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 14,43,1959 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
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