OCTADECYL DI-T-BUTYL-4-HYDROXYHYDROCINNAMATE

Antioxidant  

SCORE

1

low hazard to moderate hazard depending on product usage

3

 

88%

data gap

(why scores have changed)

Also listed as

OCTADECYL DI-t-BUTYL-4-HYDROXYHYDROCINNAMATE, BENZENEPROPANOIC ACID, 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY-, OCTADECYL ESTER; OCTADECYL 3- (2,5-DI-TERT-BUTYL-4-HYDROXYPHENYL) PROPIONATE; OCTADECYL ESTER BENZENEPROPANOIC ACID, 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY-; 3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXY- OCTADECYL ESTER BENZENEPROPANOIC ACID; BENZENEPROPANOIC ACID, 3,5BIS (1,1DIMETHYLETHYL) 4HYDROXY, OCTADECYL ESTER; OCTADECYL 3- (3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL) PROPIONATE; OCTADECYL 3,5-DI-TERT-BUTYL-4-HYDROXYHYDROCINNAMATE; OCTADECYL 3- (3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL) PROPIONATE


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
yes, moderateCancer
noDevelopmental/reproductive toxicity
noViolations, restrictions & warnings
noAllergies/immunotoxicity
noContamination concerns
noOther moderate concerns for this ingredient:
Persistence and bioaccumulation, Organ system toxicity (non-reproductive)
noLesser or emerging concerns for this ingredient:
Ecotoxicology, Data gaps
 

About OCTADECYL DI-T-BUTYL-4-HYDROXYHYDROCINNAMATE: Octadecyl Di-t-butyl-4-hydroxyhydrocinnamate is the organic compound that conforms to theformula:


Cancer

type of concern product conditions reference
Possible carcinogen     Environmental Canada Domestic Substance List

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Classified as a high human health priority     Environmental Canada Domestic Substance List
Classified as expected to be toxic or harmful     Environmental Canada Domestic Substance List

Persistence and bioaccumulation

type of concern product conditions reference
Persistent or bioaccumulative and moderate to high toxicity concern in humans     Environmental Canada Domestic Substance List
Persistent, bioaccumulative in wildlife    EU PTBs - PRIO database & Secondary PRIO database

Ecotoxicology

type of concern product conditions reference
Suspected to be an environmental toxin and be persistent or bioaccumulative     Environmental Canada Domestic Substance List
show more

Data gaps

type of concern product conditions reference
Not assessed for safety in cosmetics by industry panel  
2 studies on toxicity in PubMed see search results ->   PubMed



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Environmental Canada Domestic Substance ListBENZENEPROPANOIC ACID, 3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-, OCTADECYL ESTER•This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention.
EU PTBs - PRIO database & Secondary PRIO databaseOCTADECYL 3-(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYL)PROPIONATE•Suspected persistent, bioaccumulative toxicant - European Chemicals Bureau PBT working group

references

government/industry list/academic study reference
Environmental Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EU PTBs - PRIO database & Secondary PRIO databaseEU (European Union). 2006. Persistent, bioaccumulative chemicals identified in PRIO database - a tool for risk reduction of chemicals. Secondary PRIO database - a tool for risk reduction of chemicals. Secondary Kemi. Place Published, Kemi-Swedish Chemicals Inspectorate.

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.

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