ORGANOCHLORINES

 

SCORE

7

high hazard

 

84%

data gap

(why scores have changed)

ORGANOCHLORINES may be an impurity the following product types:
moisturizer (82)
facial moisturizer/treatment (64)
mascara (53)
shampoo (50)
anti-aging (45)
conditioner (41)
hair color and bleaching (28)
exfoliant/scrub (24)
body wash/cleanser (20)
eye liner (18)


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
yes, moderateCancer
yes, moderateDevelopmental/reproductive toxicity
noViolations, restrictions & warnings
yes, moderateAllergies/immunotoxicity
noContamination concerns
noOther moderate concerns for this ingredient:
Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Biochemical or cellular level changes
 
See ingredients that may have ORGANOCHLORINES as an impurity

See products that may have ORGANOCHLORINES as an impurity


Allergies/immunotoxicity

type of concern product conditions reference
Human skin toxicant - strong evidence    CHE Toxicant and Disease Database
Human immune toxicant - moderate evidence    CHE Toxicant and Disease Database

Cancer

type of concern product conditions reference
Cancer - strong evidence    CHE Toxicant and Disease Database
Cancer - moderate evidence - immune system    CHE Toxicant and Disease Database
show more

Neurotoxicity

type of concern product conditions reference
Moderate evidence of human neurotoxicity    CHE Toxicant and Disease Database
show more

Developmental/reproductive toxicity

type of concern product conditions reference
Human nervous system toxicant - moderate evidence    CHE Toxicant and Disease Database
Human developmental toxicant - moderate evidence    CHE Toxicant and Disease Database
Human reproductive toxicant - moderate evidence    CHE Toxicant and Disease Database
show more

Organ system toxicity (non-reproductive)

type of concern product conditions reference
Possible human hematologic toxicant    CHE Toxicant and Disease Database
show more

Endocrine disruption

type of concern product conditions reference
Limited evidence of endocrine disruption    CHE Toxicant and Disease Database

Biochemical or cellular level changes

type of concern product conditions reference
Cancer - limited evidence - immune system    CHE Toxicant and Disease Database

Data gaps

type of concern product conditions reference
467 studies on toxicity in PubMed see search results ->   PubMed



Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)
Association of Occupational and Environmental ClinicsORGANOCHLORINE PESTICIDES, NOS• P
Association of Occupational and Environmental ClinicsORGANOCHLORINE PESTICIDES, NOS• P
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: reproductive system toxicity; Condition: abnormal sperm (morphology, motility, and sperm count); Organs/tissues affected: testes
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: gastrointestinal system toxicity; Condition: acute hepatocellular injury (hepatitis); Organs/tissues affected: liver
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: hematologic system toxicity; Condition: adult-onset leukemias; Organs/tissues affected: blood
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: reproductive system toxicity; Condition: altered sex ratio; Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDESAltered time to sexual maturation (accelerated or delayed puberty) - Limited
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: hematologic system toxicity; Condition: aplastic anemia; Organs/tissues affected: bone marrow
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: immune system toxicity; Condition: autoimmune antibodies (positive ANA, anti-DNA, RF, etc.); Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: renal system toxicity; Condition: bladder cancer; Organs/tissues affected: bladder
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: reproductive system toxicity; Condition: breast cancer; Organs/tissues affected: breast
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: respiratory system toxicity; Condition: bronchitis - acute; Organs/tissues affected: lungs
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Strong evidence in humans: skin toxicity; Condition: chloracne; Organs/tissues affected: skin
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: ; Condition: Chronic Fatigue Syndrome; Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: nervous system toxicity, developmental toxicity; Condition: cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)/mental retardation/developmental delay; Organs/tissues affected: brain
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: gastrointestinal system toxicity; Condition: colo-rectal cancer; Organs/tissues affected: colon
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: nervous system toxicity; Condition: decreased coordination/ dysequilibrium; Organs/tissues affected: brain
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDESDecreased vision (includes blindness, retinopathy, optic neuropathy) - Limited
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: reproductive system toxicity; Condition: fetotoxicity (miscarriage/spontaneous abortion, stillbirth); Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: gastrointestinal system toxicity; Condition: gallbladder cancer; Organs/tissues affected: gall bladder
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: gastrointestinal system toxicity; Condition: hepatocellular cancer (liver cancer); Organs/tissues affected: liver
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDESHodgkin's Disease (lymphoma) - Limited
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: immune system toxicity; Condition: immune suppression; Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: developmental toxicity; Condition: low birth weight/small for gestational age/intra-uterine growth retardation; Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: respiratory system toxicity; Condition: lung cancer; Organs/tissues affected: lungs
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: immune system toxicity; Condition: lymphoma (non-Hodgkin's); Organs/tissues affected: lymph nodes
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: immune system toxicity; Condition: lymphoma (non-Hodgkin's); Organs/tissues affected: lymph nodes
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: reproductive system toxicity; Condition: menstrual disorders (abnormal bleeding, short cycles, long cycles, irregular cycles, painful periods); Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: nervous system toxicity; Condition: Parkinson's disease/movement disorders; Organs/tissues affected: brain
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: nervous system toxicity; Condition: peripheral neuropathy; Organs/tissues affected: peripheral nervous system
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: hematologic system toxicity; Condition: porphyria (toxic); Organs/tissues affected: multiple organs
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: reproductive system toxicity; Condition: prostate cancer; Organs/tissues affected: prostate gland
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: nervous system toxicity; Condition: psychiatric disturbances (disorientation, hallucinations, psychosis, delirium, paranoias, anxiety/depression, emotional laibility, mood changes, euphoria).; Organs/tissues affected: brain
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: reproductive system toxicity; Condition: reduced fertility - female (infertility and subfertility); Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: nervous system toxicity; Condition: seizures; Organs/tissues affected: brain
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: musculoskeletal system toxicity; Condition: soft tissue sarcoma (cancer); Organs/tissues affected: soft tissues
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Moderate evidence in humans: nervous system toxicity; Condition: spasticity/myoclonus; Organs/tissues affected:
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: reproductive system toxicity; Condition: testicular cancer; Organs/tissues affected: testes
CHE Toxicant and Disease DatabaseORGANOCHLORINE PESTICIDES•Limited evidence in humans: endocrine system toxicity; Condition: thyroid disorders - hypothyroidism; Organs/tissues affected: thyroid gland
DiPalma, J, 1107ORGANOCHLORINE PESTICIDES•Gastrointestinal or liver toxicity hazards: suspected
Merck & CoORGANOCHLORINE PESTICIDES•Kidney toxicity hazards: suspected
Proposition 65 List of CarcinogensORGANOCHLORINE PESTICIDES•Developmental toxicity hazards: suspected
Proposition 65 List of CarcinogensORGANOCHLORINE PESTICIDES•Cancer hazards: suspected
Proposition 65 List of CarcinogensORGANOCHLORINE PESTICIDES•Reproductive toxicity hazards: suspected

references

government/industry list/academic study reference
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
CHE Toxicant and Disease DatabaseCHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database.
Scorecard.org Toxicity InformationDiPalma, J.A., J. Cunningham, J. Herrera, T. McCaffery, and D. Wolf. Occupational and Industrial Toxin Exposures and the Gastrointestinal Tract. American Journal of Gastroenterology. 86(9): 1107-1117. 1991. (Table 2: Selected Agents with Purported Digestive System Injury).
Scorecard.org Toxicity InformationMerck & Co. The Merck Manual of Diagnosis and Therapy. TABLE 226-1. Common Nephrotoxic Agents http://www.merck.com/pubs/mmanual/tables/226tb1.htm
Scorecard.org Toxicity InformationProposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.-MC
Scorecard.org Toxicity InformationProposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.-MC
Scorecard.org Toxicity InformationProposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.-MC

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