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PESTICIDES

SCORE

	9	high hazard to high hazard depending on product usage
	10	high hazard to high hazard depending on product usage
	79%	data gap
(why scores have changed)

PESTICIDES may be an impurity the following product types:
mascara (198)
moisturizer (109)
facial moisturizer/treatment (85)
anti-aging (66)
lip gloss (66)
foundation (56)
lip liner (53)
shampoo (53)
eye liner (44)
facial powder (36)
eye shadow (34)
body wash/cleanser (33)
conditioner (33)
exfoliant/scrub (33)
facial cleanser (32)
brow liner (29)
lipstick (28)
hair color and bleaching (28)
around-eye cream (27)
sunscreen: makeup (22)
body oil (20)
styling gel/lotion (20)

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Other moderate concerns for this ingredient: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
	See ingredients that may have PESTICIDES as an impurity See products that may have PESTICIDES as an impurity

Cancer

type of concern

product conditions

reference

Cancer - strong evidence

CHE Toxicant and Disease Database

Cancer - moderate evidence - hematologic

CHE Toxicant and Disease Database

Cancer - moderate evidence - musculoskeletal

CHE Toxicant and Disease Database

Cancer - moderate evidence - nervous system

CHE Toxicant and Disease Database

Cancer - moderate evidence - immune system

CHE Toxicant and Disease Database

Cancer - moderate evidence - gastrointestinal

CHE Toxicant and Disease Database

Cancer - moderate evidence - renal

CHE Toxicant and Disease Database

Cancer - moderate evidence - skin

CHE Toxicant and Disease Database

Cancer - moderate evidence - developmental

CHE Toxicant and Disease Database

Neurotoxicity

type of concern

product conditions

reference

Strong evidence of human neurotoxicity

CHE Toxicant and Disease Database

Moderate evidence of human neurotoxicity

CHE Toxicant and Disease Database

Allergies/immunotoxicity

type of concern

product conditions

reference

Human immune toxicant - strong evidence

CHE Toxicant and Disease Database

Human skin toxicant - strong evidence

CHE Toxicant and Disease Database

Human immune toxicant - moderate evidence

CHE Toxicant and Disease Database

Human skin and immune toxicant - moderate evidence

CHE Toxicant and Disease Database

Developmental/reproductive toxicity

type of concern

product conditions

reference

Human reproductive toxicant - strong evidence

CHE Toxicant and Disease Database

Human reproductive toxicant - moderate evidence

CHE Toxicant and Disease Database

Human nervous system toxicant - moderate evidence

CHE Toxicant and Disease Database

Human developmental toxicant - moderate evidence

CHE Toxicant and Disease Database

Human renal toxicant - moderate evidence

CHE Toxicant and Disease Database

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

Known human cardiovascular toxicant

CHE Toxicant and Disease Database

Possible human hematologic toxicant

CHE Toxicant and Disease Database

Endocrine disruption

type of concern	product conditions	reference
Limited evidence of endocrine disruption		CHE Toxicant and Disease Database

Biochemical or cellular level changes

type of concern	product conditions	reference
Cancer - limited evidence - immune system		CHE Toxicant and Disease Database

Irritation (skin, eyes, or lungs)

type of concern	product conditions	reference
Human respiratory irritant - moderate evidence	products that may be aerosolized (airborne)	CHE Toxicant and Disease Database

Data gaps

type of concern	product conditions	reference
9,232 studies on toxicity in PubMed see search results ->		PubMed

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: abnormal sperm (morphology, motility, and sperm count); Organs/tissues affected: testes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: abnormal sperm (morphology, motility, and sperm count); Organs/tissues affected: testes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: acute hepatocellular injury (hepatitis); Organs/tissues affected: liver
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: ADD/ADHD, hyperactivity; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: adult-onset leukemias; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: hematologic system toxicity; Condition: adult-onset leukemias; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	ALS (Lou Gehrig's disease) - Limited
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: Alzheimer's; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: cardiovascular system toxicity, gastrointestinal system toxicity; Condition: angiosarcoma (cancer, hepatic); Organs/tissues affected: blood vessels, liver
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: aplastic anemia; Organs/tissues affected: bone marrow
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: hematologic system toxicity; Condition: aplastic anemia; Organs/tissues affected: bone marrow
CHE Toxicant and Disease Database	PESTICIDES	•Strong evidence in humans: cardiovascular system toxicity; Condition: arrhythmias; Organs/tissues affected: heart
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: respiratory system toxicity; Condition: asthma - irritant; Organs/tissues affected: lungs
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: immune system toxicity; Condition: autoimmune antibodies (positive ANA, anti-DNA, RF, etc.); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: behavioral problems; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: renal system toxicity; Condition: bladder cancer; Organs/tissues affected: bladder
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: musculoskeletal system toxicity; Condition: bone cancer/Ewings sarcoma; Organs/tissues affected: bone
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: brain cancer (adult); Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: brain cancer - childhood; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: brain cancer - childhood; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: breast cancer; Organs/tissues affected: breast
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: bronchitis - acute; Organs/tissues affected: lungs
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: bronchitis - chronic; Organs/tissues affected: lungs
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: cardiovascular system toxicity, developmental toxicity; Condition: cardiac congenital malformations (birth defects); Organs/tissues affected: heart
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: cervical cancer; Organs/tissues affected: uterus
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: childhood leukemias; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: hematologic system toxicity; Condition: childhood leukemias; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: ; Condition: Chronic Fatigue Syndrome; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: cirrhosis; Organs/tissues affected: liver
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity, developmental toxicity; Condition: cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)/mental retardation/developmental delay; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: colo-rectal cancer; Organs/tissues affected: colon
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: developmental toxicity; Condition: congenital malformations (birth defects); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Strong evidence in humans: skin toxicity, immune system toxicity; Condition: contact dermatitis - allergic; Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Strong evidence in humans: skin toxicity; Condition: contact dermatitis - irritant; Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: decreased coordination/ dysequilibrium; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	Decreased vision (includes blindness, retinopathy, optic neuropathy) - Limited
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: early onset menopause; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: esophageal cancer; Organs/tissues affected: esophagus
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: fetotoxicity (miscarriage/spontaneous abortion, stillbirth); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: fetotoxicity (miscarriage/spontaneous abortion, stillbirth); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: renal system toxicity, reproductive system toxicity, developmental toxicity; Condition: genito-urinary malformations (includes male and female); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: renal system toxicity, reproductive system toxicity, developmental toxicity; Condition: genito-urinary malformations (includes male and female); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: ; Condition: Gulf War Syndrome; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: hepatocellular cancer (liver cancer); Organs/tissues affected: liver
CHE Toxicant and Disease Database	PESTICIDES	Hodgkin's Disease (lymphoma) - Limited
CHE Toxicant and Disease Database	PESTICIDES	Hormonal changes (levels of circulating sex hormones - FSH/LH, Inhibin, and/or estrogens, progesterones, androgens) - Good
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: immune system toxicity; Condition: immune suppression; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: immune system toxicity; Condition: immune suppression; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: laryngeal cancer; Organs/tissues affected: larynx
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: developmental toxicity; Condition: low birth weight/small for gestational age/intra-uterine growth retardation; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: lung cancer; Organs/tissues affected: lungs
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: immune system toxicity; Condition: lymphoma (non-Hodgkin's); Organs/tissues affected: lymph nodes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: immune system toxicity; Condition: lymphoma (non-Hodgkin's); Organs/tissues affected: lymph nodes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: skin toxicity; Condition: melanoma (skin cancer); Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: menstrual disorders (abnormal bleeding, short cycles, long cycles, irregular cycles, painful periods); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: ; Condition: Multiple Chemical Sensitivity; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: multiple myeloma; Organs/tissues affected: bone marrow
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: Multiple Sclerosis; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: immune system toxicity; Condition: mycosis fungoides (cutaneous T-cell lymphoma); Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: immune system toxicity; Condition: mycosis fungoides (cutaneous T-cell lymphoma); Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: myelodysplastic syndrome (pre-leukemia); Organs/tissues affected: bone marrow
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: nasopharyngeal/sino-nasal cancer; Organs/tissues affected: nose, sinuses
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity, developmental toxicity; Condition: neural tube defects/central nervous system malformations; Organs/tissues affected: neural tube
CHE Toxicant and Disease Database	PESTICIDES	Oral clefts (cleft lip and palate) - Limited
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: ovarian cancer; Organs/tissues affected: ovaries
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: gastrointestinal system toxicity; Condition: pancreatic cancer; Organs/tissues affected: pancreas
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: pancreatic cancer; Organs/tissues affected: pancreas
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: Parkinson's disease/movement disorders; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: nervous system toxicity; Condition: Parkinson's disease/movement disorders; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Strong evidence in humans: nervous system toxicity; Condition: peripheral neuropathy; Organs/tissues affected: peripheral nervous system
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: peripheral neuropathy; Organs/tissues affected: peripheral nervous system
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: skin toxicity, immune system toxicity; Condition: photosensitivity; Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: respiratory system toxicity; Condition: pneumonia; Organs/tissues affected: lungs
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: hematologic system toxicity; Condition: porphyria (toxic); Organs/tissues affected: multiple organs
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: prostate cancer; Organs/tissues affected: prostate gland
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: prostate cancer; Organs/tissues affected: prostate gland
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: psychiatric disturbances (disorientation, hallucinations, psychosis, delirium, paranoias, anxiety/depression, emotional laibility, mood changes, euphoria).; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: reduced fertility - female (infertility and subfertility); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: reduced fertility - female (infertility and subfertility); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Strong evidence in humans: reproductive system toxicity; Condition: reduced fertility - male (infertility and subfertility); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: reduced fertility - male (infertility and subfertility); Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: renal system toxicity; Condition: renal (kidney) cancer; Organs/tissues affected: kidney
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: renal system toxicity; Condition: renal (kidney) cancer; Organs/tissues affected: kidney
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: sense organ system toxicity; Condition: retinoblastoma (cancer); Organs/tissues affected: eyes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: immune system toxicity; Condition: rheumatoid arthritis; Organs/tissues affected: joints
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: seizures; Organs/tissues affected: brain
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: musculoskeletal system toxicity, developmental toxicity; Condition: skeletal malformations; Organs/tissues affected: bone
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: skin toxicity; Condition: skin cancer (non-melanoma); Organs/tissues affected: skin
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: musculoskeletal system toxicity; Condition: soft tissue sarcoma (cancer); Organs/tissues affected: soft tissues
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: nervous system toxicity; Condition: spasticity/myoclonus; Organs/tissues affected:
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: gastrointestinal system toxicity; Condition: stomach cancer; Organs/tissues affected: stomach
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: testicular atrophy; Organs/tissues affected: testes
CHE Toxicant and Disease Database	PESTICIDES	•Moderate evidence in humans: reproductive system toxicity; Condition: testicular cancer; Organs/tissues affected: testes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: testicular cancer; Organs/tissues affected: testes
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: hematologic system toxicity; Condition: thrombocytopenia; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: hematologic system toxicity; Condition: thrombocytopenic purpura; Organs/tissues affected: blood
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: endocrine system toxicity; Condition: thyroid cancer; Organs/tissues affected: thyroid gland
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: endocrine system toxicity; Condition: thyroid disorders - hypothyroidism; Organs/tissues affected: thyroid gland
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: reproductive system toxicity; Condition: uterine cancer; Organs/tissues affected: uterus
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: cardiovascular system toxicity; Condition: vasculitis; Organs/tissues affected: blood vessels
CHE Toxicant and Disease Database	PESTICIDES	•Limited evidence in humans: renal system toxicity; Condition: Wilm's tumor; Organs/tissues affected: kidney

references

government/industry list/academic study	reference
CHE Toxicant and Disease Database	CHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database.

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