HEXAHYDRO-1,3,5-TRIS (2-HYDROXYETHYL)-S-TRIAZINE
Also listed as
1,3,5-TRIS(2-HYDROXYETHYL)HEXAHYDRO-1,3,5-TRIAZINE, 2,2',2"- (HEXAHYDRO-1,3,5-TRIAZINE-1,3,5-TRIYL) TRIETHANOL; 1,3,5-TRIS (2-HYDROXYETHYL) HEXAHYDRO-1,3,5-TRIAZINE; 1,3,5-TRIAZINE-1,3,5 (2H,4H,6H) -TRIETHANOL (9CI) ; 1,3,5-TRIS (BETA-HYDROXYETHYL) -HEXAHYDRO-S-TRIAZINE; ACTANE; BUSAN 1060; ETA 75; GROTAN B; GROTAN BK; HEXAHYDRO-1,3,5-TRIS (HYDROXYETHYL) TRIAZINE; KALPUR TE; KM 200 (ALCOHOL)
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
 | Allergies/immunotoxicity |
| Contamination concerns |
| Other strong concerns for this ingredient: Occupational hazards |
 | Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive) |
| Lesser or emerging concerns for this ingredient: Data gaps |
Allergies/immunotoxicity
| type of concern | product conditions | reference |
| Known human immune system toxicant | National Library of Medicine HazMap | |
| Limited evidence of immune system toxicity | products for use on skin | European Union - Classification & Labelling |
Occupational hazards
| type of concern | product conditions | reference |
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Classified as toxic or harmful | products for use around the mouth; products for use on the lips | European Union - Classification & Labelling |
| show more | ||
Cancer
| type of concern | product conditions | reference |
| One or more in vitro tests non-mammalian cells show positive mutation results | RTECS®- Environmental Mutagenesis 1986 | |
| show more | ||
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Not suspected to be persistent | Environmental Canada Domestic Substance List | |
| show more | ||
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| European Union - Classification & Labelling | 2,2',2""-(HEXAHYDRO-1,3,5-TRIAZINE-1,3,5-TRIYL)TRIETHANOL; 1,3,5-TRIS(2-HYDROXYETHYL)HEXAHYDRO-1,3,5-TRIAZINE | •Harmful •Harmful if swallowed •May cause sensitization by skin contact |
| Environmental Canada Domestic Substance List | 1,3,5-TRIAZINE-1,3,5(2H,4H,6H)-TRIETHANOL | •This chemical was NOT flagged by CEPA for further attention. |
| National Library of Medicine HazMap | GROTAN BK | •Skin Sensitizer - An agent that can induce an allergic reaction in the skin or lungs: Yes; |
| RTECS®- Environmental Mutagenesis 1986 | HEXAHYDRO-1,3,5-TRIS (2-HYDROXYETHYL)-S-TRIAZINE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
| RTECS®- Toxicology and Industrial Health 2002 | HEXAHYDRO-1,3,5-TRIS (2-HYDROXYETHYL)-S-TRIAZINE | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) |
references
| government/industry list/academic study | reference |
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex I of Directive 67/548/EEC through the 31st ATP. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| RTECS®- Environmental Mutagenesis 1986 | RTECS®- Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. 8(Suppl 7),1,1986 |
| RTECS®- Toxicology and Industrial Health 2002 | RTECS®- Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 18,425,2002 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
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