2-NITRO-P-PHENYLENEDIAMINE || Skin Deep: Cosmetic Safety Reviews

2-NITRO-P-PHENYLENEDIAMINE

Hair Colorant; HAIR DYEING

SCORE

	7	high hazard
	55%	data gap
(why scores have changed)

Also listed as

2-NITRO-p-PHENYLENEDIAMINE, 4-AMINO-2-NITROANILINE; 1,4-BENZENEDIAMINE, 2-NITRO-; CI 76070; 2,5-DIAMINONITROBENZENE; 2-NITRO-1,4-DIAMINOBENZENE; O-NITRO-P-PHENYLENEDIAMINE; 2-NITRO- 1,4-BENZENEDIAMINE; 1,4BENZENEDIAMINE, 2NITRO; 1,4-DIAMINO-2-NITROBENZENE; 1,4-DIAMINONITROBENZOL (GERMAN) ; 2-NITRO-1,4-BENZENEDIAMINE

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Lesser or emerging concerns for this ingredient: Organ system toxicity (non-reproductive), Data gaps
	See products containing 2-NITRO-P-PHENYLENEDIAMINE

About 2-NITRO-P-PHENYLENEDIAMINE: 2-Nitro-p-Phenylenediamine is the substituted aromatic amine. See "Regulatory and Ingredient Use Information," for Colorants in Volume 1, Introduction, Part A.

Allergies/immunotoxicity

type of concern	product conditions	reference
Known human immune system toxicant		National Library of Medicine HazMap
Human skin toxicant - strong evidence		Cosmetic Ingredient Review Assessments
Human skin toxicant - strong evidence

Violations, restrictions & warnings

type of concern	product conditions	reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		Cosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		Cosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations -		CTFA International Cosmetic Ingredient Dictionary and Handbook

Cancer

type of concern

product conditions

reference

Cancer - moderate evidence - Coal tar dye - laboratory studies show carcinogenic effect from exposures; epidemiology studies link long-time use of coal tar hair dye to increased risk of bladder cancer

Cosmetic Ingredient Review Assessments

Cancer - limited evidence		CTFA International Cosmetic Ingredient Dictionary and Handbook
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Cancer Research 1978
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Nature 1975
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Mutation Research 1982
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Mutation Research 1979
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Cytologia 1992
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Environmental and Molecular Mutagenesis 1988
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Nature 1976
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Mutation Research 1988
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Journal of Environmental Pathology and Toxicology 1977
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Mutation Research 1992
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- National Cancer Institute, Monograph 1981
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Environmental and Molecular Mutagenesis 1996
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Mutation Research 1977
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Archives of Toxicology, Supplement 1980
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Basic Life Sciences 1984
One or more in vitro tests on mammalian cells show positive mutation results		RTECS^®- Environmental and Molecular Mutagenesis 1990
Cancer - not classifiable/not likely to be human carcinogen		Int'l Agency for Research on Cancer (IARC) - Carcinogens
One or more in vitro tests non-mammalian cells show positive mutation results		RTECS^®- Nature 1975
One or more in vitro tests non-mammalian cells show positive mutation results		RTECS^®- Environmental Mutagenesis 1985
One or more in vitro tests non-mammalian cells show positive mutation results		RTECS^®- Mutation Research 1992
One or more animal studies show tumor formation at high doses		RTECS^®- National Cancer Institute Carcinogenesis Technical Report Series 1979

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)

RTECS^®- Journal of Toxicology and Environmental Health 1977

Developmental/reproductive toxicity

type of concern

product conditions

reference

One or more animal studies show reproductive effects at high doses

RTECS^®- Teratology, The International Journal of Abnormal Development 1979

Data gaps

type of concern	product conditions	reference
Missing safety data noted by cosmetic industry review		Cosmetic Ingredient Review Assessments
Insufficient data to determine safety		Cosmetic Ingredient Review Assessments
36 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be persistent

Environmental Canada Domestic Substance List

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Cosmetic Ingredient Review Assessments	2-NITRO-P-PHENYLENEDIAMINE	•Safe for use in cosmetics with some qualifications •Distinction between safe conc in leave-on and rinse-off products • • •Sensitizer - can instigate immune system response that can include itching, burning, scaling, hives, and blistering of skin •Coal tar dye - laboratory studies show carcinogenic effect from exposures; epidemiology studies link long-time use of coal tar hair dye to increased risk of bladder cancer
Environmental Canada Domestic Substance List	1,4-BENZENEDIAMINE, 2-NITRO-	•This chemical was NOT flagged by CEPA for further attention.
CTFA International Cosmetic Ingredient Dictionary and Handbook	2-NITRO-P-PHENYLENEDIAMINE	•Color Additives - Hair (Coal Tar Dye)
National Library of Medicine HazMap	2-NITRO-4-PHENYLENEDIAMINE	•Skin Sensitizer - An agent that can induce an allergic reaction in the skin or lungs: Yes;
Int'l Agency for Research on Cancer (IARC) - Carcinogens	1,4-DIAMINO-2-NITROBENZENE	•IARC Group 3 (no cancer link)
Cosmetic Ingredient Review Assessments	COAL TAR	•Insufficient data to support safe use in cosmetics •Industry safety panel (Cosmetic Ingredient Review, CIR) notes missing safety data in its review of this ingredient •Determined safe for use in cosmetics up to a specified concentration limit •Product type restrictions or differences noted in safety assessment by industry panel • • •Sensitizer - can instigate immune system response that can include itching, burning, scaling, hives, and blistering of skin
RTECS^®- Archives of Toxicology, Supplement 1980	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS^®- Archives of Toxicology, Supplement 1980	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng)
RTECS^®- Basic Life Sciences 1984	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster orl)
RTECS^®- Basic Life Sciences 1984	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster orl)
RTECS^®- Cancer Research 1978	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis ( human hla)
RTECS^®- Cancer Research 1978	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis ( human hla)
RTECS^®- Cytologia 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Micronucleus test (mouse ipr)
RTECS^®- Cytologia 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Micronucleus test (mouse ipr)
RTECS^®- Environmental and Molecular Mutagenesis 1988	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym)
RTECS^®- Environmental and Molecular Mutagenesis 1990	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: (hamster ovr)
RTECS^®- Environmental and Molecular Mutagenesis 1996	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr)
RTECS^®- Environmental and Molecular Mutagenesis 1988	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym)
RTECS^®- Environmental and Molecular Mutagenesis 1990	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: (hamster ovr)
RTECS^®- Environmental and Molecular Mutagenesis 1996	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster ovr)
RTECS^®- Environmental Mutagenesis 1985	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Escherichia coli )
RTECS^®- Genetica Polonica 1985	2-NITRO-P-PHENYLENEDIAMINE	• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS^®- Journal of Environmental Pathology and Toxicology 1977	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells (mouse lym)
RTECS^®- Journal of the Society of Cosmetic Chemists 1972	2-NITRO-P-PHENYLENEDIAMINE	• kidney or renal system - Other changes in urine composition (rat LD50)
RTECS^®- Journal of Toxicology and Environmental Health 1977	2-NITRO-P-PHENYLENEDIAMINE	• broad systemic - Broad systemic toxicity (rat LD50)
RTECS^®- Mutation Research 1988	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: DNA Damage (mouse lym)
RTECS^®- Mutation Research 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: DNA repair (Escherichia coli )
RTECS^®- Mutation Research 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Host-mediated Assay (mouse )
RTECS^®- Mutation Research 1977	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS^®- Mutation Research 1977	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr)
RTECS^®- Mutation Research 1979	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: body fluid assay (rat )
RTECS^®- Mutation Research 1982	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr)
RTECS^®- Mutation Research 1988	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: DNA Damage (mouse lym)
RTECS^®- Mutation Research 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: DNA repair (Escherichia coli )
RTECS^®- Mutation Research 1992	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Host-mediated Assay (mouse )
RTECS^®- Mutation Research 1977	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr)
RTECS^®- Mutation Research 1977	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Sister Chromatid Exchange (hamster ovr)
RTECS^®- Mutation Research 1979	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: body fluid assay (rat )
RTECS^®- Mutation Research 1982	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr)
RTECS^®- National Cancer Institute Carcinogenesis Technical Report Series 1979	2-NITRO-P-PHENYLENEDIAMINE	• cancer - liver neoplasms (mouse TDLo) • cancer - liver tumor formations - equivocal (mouse TD)
RTECS^®- National Cancer Institute, Monograph 1981	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Morphological Transform (hamster emb)
RTECS^®- National Cancer Institute, Monograph 1981	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Morphological Transform (hamster emb)
RTECS^®- Nature 1975	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)
RTECS^®- Nature 1976	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster oth) • mutagenic - Positive mutation assay: Morphological Transform (mouse emb)
RTECS^®- Nature 1975	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: Cytogenetic Analysis ( human lym)
RTECS^®- Nature 1976	2-NITRO-P-PHENYLENEDIAMINE	• mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster oth) • mutagenic - Positive mutation assay: Morphological Transform (mouse oth)
RTECS^®- Teratology, The International Journal of Abnormal Development 1979	2-NITRO-P-PHENYLENEDIAMINE	• developmental - Cardiovascular (mouse TDLo) • reproductive - Fetotoxicity (mouse TDLo)
RTECS^®- Teratology, The International Journal of Abnormal Development 1981	2-NITRO-P-PHENYLENEDIAMINE	• reproductive - Craniofacial (mouse TDLo) • reproductive - Fetotoxicity (mouse TDLo) • reproductive - Post-implantation mortality (mouse TDLo)

references

government/industry list/academic study	reference
Cosmetic Ingredient Review Assessments	CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
CTFA International Cosmetic Ingredient Dictionary and Handbook	CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
National Library of Medicine HazMap	NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - Carcinogens	IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
RTECS^®- Archives of Toxicology, Supplement 1980	RTECS^®- Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- 4,41,1980
RTECS^®- Archives of Toxicology, Supplement 1980	RTECS^®- Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 4,41,1980
RTECS^®- Basic Life Sciences 1984	RTECS^®- Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- 29B,613,1984
RTECS^®- Basic Life Sciences 1984	RTECS^®- Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 29B,613,1984
RTECS^®- Cancer Research 1978	RTECS^®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- 38,2621,1978
RTECS^®- Cancer Research 1978	RTECS^®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 38,2621,1978
RTECS^®- Cytologia 1992	RTECS^®- Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- -1929 57,149,1992
RTECS^®- Cytologia 1992	RTECS^®- Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1929- 57,149,1992
RTECS^®- Environmental and Molecular Mutagenesis 1988	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- 12(Suppl 13),103,1988
RTECS^®- Environmental and Molecular Mutagenesis 1990	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- 16,260,1990
RTECS^®- Environmental and Molecular Mutagenesis 1996	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- 27,67,1996
RTECS^®- Environmental and Molecular Mutagenesis 1988	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 12(Suppl 13),103,1988
RTECS^®- Environmental and Molecular Mutagenesis 1990	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 16,260,1990
RTECS^®- Environmental and Molecular Mutagenesis 1996	RTECS^®- Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 27,67,1996
RTECS^®- Environmental Mutagenesis 1985	RTECS^®- Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. 7(Suppl 5),1,1985
RTECS^®- Genetica Polonica 1985	RTECS^®- Genetica Polonica. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1960- 26,109,1985
RTECS^®- Journal of Environmental Pathology and Toxicology 1977	RTECS^®- Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. 1(1),87,1977
RTECS^®- Journal of the Society of Cosmetic Chemists 1972	RTECS^®- Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947- 23,259,1972
RTECS^®- Journal of Toxicology and Environmental Health 1977	RTECS^®- Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- 2,657,1977
RTECS^®- Mutation Research 1988	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 203,155,1988
RTECS^®- Mutation Research 1992	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 272,145,1992
RTECS^®- Mutation Research 1992	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 272,161,1992
RTECS^®- Mutation Research 1977	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 48,337,1977
RTECS^®- Mutation Research 1977	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 56,207,1977
RTECS^®- Mutation Research 1979	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 66,241,1979
RTECS^®- Mutation Research 1982	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 97,359,1982
RTECS^®- Mutation Research 1988	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 203,155,1988
RTECS^®- Mutation Research 1992	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 272,145,1992
RTECS^®- Mutation Research 1992	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 272,161,1992
RTECS^®- Mutation Research 1977	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 48,337,1977
RTECS^®- Mutation Research 1977	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 56,207,1977
RTECS^®- Mutation Research 1979	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 66,241,1979
RTECS^®- Mutation Research 1982	RTECS^®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 97,359,1982
RTECS^®- National Cancer Institute Carcinogenesis Technical Report Series 1979	RTECS^®- National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. NCI-TR-169,1979
RTECS^®- National Cancer Institute, Monograph 1981	RTECS^®- National Cancer Institute, Monograph. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) No.1- 58,243,1981
RTECS^®- National Cancer Institute, Monograph 1981	RTECS^®- National Cancer Institute, Monograph. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) No.1- 1959- 58,243,1981
RTECS^®- Nature 1975	RTECS^®- Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- 255,506,1975
RTECS^®- Nature 1976	RTECS^®- Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- 260,368,1976
RTECS^®- Nature 1975	RTECS^®- Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 255,506,1975
RTECS^®- Nature 1976	RTECS^®- Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 260,368,1976
RTECS^®- Teratology, The International Journal of Abnormal Development 1979	RTECS^®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 19,37A,1979
RTECS^®- Teratology, The International Journal of Abnormal Development 1981	RTECS^®- Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- 24,253,1981

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