ALUMINUM STARCH OCTENYLSUCCINATE || Skin Deep: Cosmetic Safety Reviews

ALUMINUM STARCH OCTENYLSUCCINATE

Absorbent; Anticaking Agent; Viscosity Increasing Agent - Nonaqueous; VISCOSITY CONTROLLING

SCORE

	9	high hazard
	74%	data gap
(why scores have changed)

Also listed as

STARCH, HYDROGEN OCTENYLBUTANEDIOATE, ALUMINUM SALT; ALUMINUM SALT STARCH, HYDROGEN OCTENYLBUTANEDIOATE; HYDROGEN OCTENYLBUTANEDIOATE ALUMINUM SALT STARCH; ALUMINUM STARCH OCTENYLBUTANEDIOATE; STARCH ALUMINUM OCTENYLSUCCINATE

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns - ARSENIC, LEAD, HEAVY METALS
	Other moderate concerns for this ingredient: Neurotoxicity, Organ system toxicity (non-reproductive)
	See products containing ALUMINUM STARCH OCTENYLSUCCINATE

About ALUMINUM STARCH OCTENYLSUCCINATE: Aluminum Starch Octenylsuccinate is the aluminum salt of the reaction product ofoctenylsuccinic anhydride with starch.

ALUMINUM STARCH OCTENYLSUCCINATE has reported used in the following product types: foundation (91); facial moisturizer/treatment (67); anti-aging (57); eye shadow (48); sunscreen: makeup (41); concealer (36); moisturizer (29); sunscreen: moisturizer (28); lipstick (28); facial powder (28)

Neurotoxicity

type of concern	product conditions	reference
Strong evidence of human neurotoxicity		Chemicals known to be neurotoxic to humans

Developmental/reproductive toxicity

type of concern	product conditions	reference
Human nervous system toxicant - moderate evidence		Chemicals known to be neurotoxic to humans

Violations, restrictions & warnings

type of concern	product conditions	reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		Cosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

Limited evidence of toxicity

Klaassen, C

Data gaps

type of concern	product conditions	reference
1 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Ecotoxicology

type of concern	product conditions	reference
Uncertain environmental toxin and uncertain persistent or bioaccumulative		Environmental Canada Domestic Substance List

Multiple, additive exposure sources

type of concern	product conditions	reference
Designated as safe for general or specific, limited use in food		FDA Everything Added to Food

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Cosmetic Ingredient Review Assessments	ALUMINUM STARCH OCTENYLSUCCINATE	•Safe for use in cosmetics with some qualifications •Restrictions on impurities recommended by industry safety panel •May contain harmful impurities
FDA Everything Added to Food	STARCH, FOOD, MODIFIED: STARCH ALUMINUM OCTENYL SUCCINATE	• Fully up-to-date toxicology information has been sought.
Environmental Canada Domestic Substance List	STARCH, HYDROGEN OCTENYLBUTANEDIOATE, ALUMINUM SALT	•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for uncertain persistence, uncertain bioaccumulation, and uncertain aquatic toxicity.
Chemicals known to be neurotoxic to humans	ALUMINUM COMPOUNDS	•Known to be neurotoxic to humans, suspected developmental neurotoxin
Klaassen, C	ALUMINUM COMPOUNDS	•Respiratory toxicity hazards: suspected

references

government/industry list/academic study	reference
Cosmetic Ingredient Review Assessments	CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
Chemicals known to be neurotoxic to humans	Grandjean P and PJ Landrigan. 2006. Developmental neurotoxicity of industrial chemicals. Lancet. 2006 Dec 16;368(9553):2167-78.
Scorecard.org Toxicity Information	Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull

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