CALCIUM CARBONATE || Skin Deep: Cosmetic Safety Reviews

CALCIUM CARBONATE

Abrasive; Buffering Agent; Bulking Agent; Opacifying Agent; Oral Care Agent

SCORE

	1	low hazard
	87%	data gap
(why scores have changed)

Also listed as

CALCIUM CARBONATE, PRECIPITATED; CARBONIC ACID, CALCIUM SALT; HEAVY CALCIUM CARBONATE; PRECIPITATED CALCIUM CARBONATE; PRECIPITATED CHALK; CALCIUM SALT CARBONIC ACID; CALCIUM CARBONATE; CALCIUM CARBONATE; SLAKER REJECTS; CARBONIC ACID CALCIUM SALT (1:1) ; AEROMATT; AGRICULTURAL LIMESTONE; AGSTONE

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Other strong concerns for this ingredient: Enhanced skin absorption
	Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
	Lesser or emerging concerns for this ingredient: Data gaps
	See products containing CALCIUM CARBONATE

About CALCIUM CARBONATE: Calcium Carbonate is the inorganic salt.

CALCIUM CARBONATE has reported used in the following product types: toothpaste (64); facial powder (33); foundation (31); eye liner (13); concealer (11); blush (9); eye shadow (9); tooth whitening (9); bronzer/highlighter (7); body powder (6)

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show sense organ effects at very low doses

products for use around the eyes, mouth, or lips

RTECS^®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972

Occupational hazards

type of concern	product conditions	reference
Allowed workplace exposures restricted to moderate doses		RTECS^®- TLV/BEI,2006
Allowed workplace exposures restricted to moderate doses		RTECS^®- TLV/BEI,2005

Irritation (skin, eyes, or lungs)

type of concern	product conditions	reference
One or more animal studies show skin irritation at low doses		RTECS^®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972

Enhanced skin absorption

type of concern	product conditions	reference
Suspected nano-scale ingredients with potential to absorb into the skin		Nanomaterial Database

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Multiple, additive exposure sources

type of concern	product conditions	reference
Designated as safe for general or specific, limited use in food		FDA Food Additive Status
Designated as safe for general or specific, limited use in food		FDA Everything Added to Food

Persistence and bioaccumulation

type of concern	product conditions	reference
Not suspected to be bioaccumulative		Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
FDA Food Additive Status	CALCIUM CARBONATE	• miscellaneous • Substances generally recognized as safe in foods but limited in standardized foods where the standard provides for its use • refers to part number under Title 21 Code of Federal Regulations 137 • admixed w/benzoyl peroxide for bleaching flour • refers to part number under Title 21 Code of Federal Regulations 136 • Bakery Pdts • refers to part number under Title 21 Code of Federal Regulations 135 • Frozen Desserts • refers to part number under Title 21 Code of Federal Regulations 582 • Animal feeds • 184.1191 • Food additive: emulsifier • Food additive: food additive for which a petition has been filed and a regulation issued • Comb w/any other optional emulsifying ingredients listed in 169.115 including sodium he
Association of Occupational and Environmental Clinics	CALCIUM CARBONATE	• o
FDA Color Additive Status	CALCIUM CARBONATE	Cosmetics: U; Food: U; Drugs: Y; Eye: U
FDA Everything Added to Food	CALCIUM CARBONATE	• Fully up-to-date toxicology information has been sought.
Environmental Canada Domestic Substance List	CARBONIC ACID CALCIUM SALT (1:1)	•This chemical was deemed a low human health priority and was NOT flagged by CEPA for further attention. The chemical was flagged for suspected persistence.
Nanomaterial Database	CALCIUM CARBONATE	•potential nano-scale ingredient
RTECS^®- TLV/BEI,2005	CALCIUM CARBONATE	• occupationally related - ACGIH TLV (human TWA)
RTECS^®- TLV/BEI,2006	CALCIUM CARBONATE	• occupationally related - ACGIH TLV (human TWA)
RTECS^®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972	CALCIUM CARBONATE	• broad systemic - Broad systemic toxicity (rat LD50) • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit )
RTECS^®- United States Environmental Protection Agency, Office of Pesticides and Toxic Substances 1994	CALCIUM CARBONATE	• gastrointestinal - Hypermotility, diarrhea (rat TDLo) • gastrointestinal - Other changes (rat TDLo)

references

government/industry list/academic study	reference
FDA Food Additive Status	FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental Clinics	AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
FDA Color Additive Status	FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
Nanomaterial Database	NanoWerk. 2007. Nanomaterial Database. Available online: http://www.nanowerk.com/phpscripts/n_dbsearch.php
RTECS^®- TLV/BEI,2005	RTECS^®- TLV/BEI,2005
RTECS^®- TLV/BEI,2006	RTECS^®- TLV/BEI,2006
RTECS^®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J 1972	RTECS^®- "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 -,267,1972
RTECS^®- United States Environmental Protection Agency, Office of Pesticides and Toxic Substances 1994	RTECS^®- United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. #86940001000,1994

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