HEXYL CINNAMAL
Fragrance Ingredient; MASKING
Also listed as
ALPHA-HEXYLCINNAMALDEHYDE; HEXYL CINNAMIC ALDEHYDE; OCTANAL, 2- (PHENYLMETHYLENE) -; 2- (PHENYLMETHYLENE) - OCTANAL; HEXYLCINNAMIC ALDEHYDE; OCTANAL, 2 (PHENYLMETHYLENE) ; 2-HEXYLCINNAMALDEHYDE; ALPHA-HEXYLCINNAMALDEHYDE; ALPHA-HEXYLCINNAMIC ALDEHYDE; ALPHA-HEXYLCINNAMYL ALDEHYDE; ALPHA-N-HEXYL-BETA-PHENYLACROLEIN
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
 | Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
| Other moderate concerns for this ingredient: Irritation (skin, eyes, or lungs) |
 | Lesser or emerging concerns for this ingredient: Neurotoxicity, Organ system toxicity (non-reproductive), Data gaps |
|
See products containing HEXYL CINNAMAL | |
About HEXYL CINNAMAL: Hexyl Cinnamal is the organic compound.
HEXYL CINNAMAL has reported used in the following product types: hair color and bleaching (144); moisturizer (69); fragrance for women (67); styling gel/lotion (64); conditioner (62); facial moisturizer/treatment (53); lipstick (49); body wash/cleanser (35); shampoo (35); hair spray (32)
Allergies/immunotoxicity
| type of concern | product conditions | reference |
| Possible human immune system toxicant | EU Banned and Restricted Fragrances |
Violations, restrictions & warnings
| type of concern | product conditions | reference |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | International Fragrance Association Codes & Standards |
Neurotoxicity
| type of concern | product conditions | reference |
| One or more animal studies show brain and nervous system effects at high doses | RTECS®- "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia" 1984 | |
| show more | ||
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| One or more animal studies show skin irritation at very low doses | RTECS®- Cosmetics and Toiletries 1979 | |
| show more | ||
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show respiratory effects at high doses (low dose studies may be unavailable for this ingredient) | products that may be aerosolized (airborne) | RTECS®- "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia" 1984 |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 41 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed |
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Not suspected to be bioaccumulative | Environmental Canada Domestic Substance List | |
| show more | ||
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| FDA Everything Added to Food | ALPHA-HEXYLCINNAMALDEHYDE | • Fully up-to-date toxicology information has been sought. |
| Environmental Canada Domestic Substance List | OCTANAL, 2-(PHENYLMETHYLENE)- | •This chemical was NOT flagged by CEPA for further attention. |
| EU Banned and Restricted Fragrances | HEXYL CINNAMAL | Fragrance chemical, which is less frequently reported and thus less documented as a consumer allergen. |
| IFRA Fragrance Ingredient List | ALPHA-HEXYLCINNAMALDEHYDE | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| International Fragrance Association Codes & Standards | ALPHA-HEXYL CINNAMIC ALDEHYDE | •Fragrance subject to restrictions: safe only within recommended use or concentration limits |
| RTECS®- "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia" 1984 | HEXYL CINNAMAL | • respiratory - Respiratory depression (mouse LD50) • brain and nervous system - Somnolence (general depressed activity) (mouse LD50) |
| RTECS®- Contact Dermatitis 2001 | HEXYL CINNAMAL | • skin - Cutaneous sensitization (experimental) (mouse TDLo) |
| RTECS®- Cosmetics and Toiletries 1979 | HEXYL CINNAMAL | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Cosmetics and Toiletries 1979 | HEXYL CINNAMAL | • skin - Primary skin irritant (rabbit ) |
| RTECS®- Food and Cosmetics Toxicology 1974 | HEXYL CINNAMAL | • broad systemic - Broad systemic toxicity (rat LD50) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Gigiena i Sanitariya 1990 | HEXYL CINNAMAL | • respiratory - Dyspnea (mouse LD50) • sense organ - Other changes (mouse LD50) • brain and nervous system - Somnolence (general depressed activity) (mouse LD50) |
references
| government/industry list/academic study | reference |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EU Banned and Restricted Fragrances | SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 1999. Opinion Concerning Fragrance Allergy In Consumers. . SCCNFP/0017/98 Final, December 1999; and SCCPNFP (Scientific Committee On Cosmetic Products And Non-Food Products). 2000. An Initial List Of Perfumery Materials Which Must Not Form Part Of Fragrances Compounds Used In Cosmetic Products. SCCNFP/0320/00, final May 2000. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| International Fragrance Association Codes & Standards | IFRA (International Fragrance Association). 2006. Codes and Standards. |
| RTECS®- "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia" 1984 | RTECS®- "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994 -,401,1984 |
| RTECS®- Contact Dermatitis 2001 | RTECS®- Contact Dermatitis. Environmental and Occupational Dermatitis. (Munksgaard International Pub., c/o Publications Expediting Inc., 200 Meacham Ave., Elmont, NY 11003) V.1- 1975- 45,89,2001 |
| RTECS®- Cosmetics and Toiletries 1979 | RTECS®- Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- 94(8),41,1979 |
| RTECS®- Cosmetics and Toiletries 1979 | RTECS®- Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 94(8),41,1979 |
| RTECS®- Food and Cosmetics Toxicology 1974 | RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 12,915,1974 |
| RTECS®- Gigiena i Sanitariya 1990 | RTECS®- Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- 55(6),86,1990 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
All rights reserved.
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