LAURAMIDE DEA
Surfactant - Foam Booster; Viscosity Increasing Agent - Aqueous; ANTISTATIC; FOAM BOOSTING; VISCOSITY CONTROLLING
Also listed as
N,N-BIS (2-HYDROXYETHYL) DODECANAMIDE; N,N-BIS (2-HYDROXYETHYL) LAURAMIDE; DIETHANOLAMINE LAURIC ACID AMIDE; N,N-DIETHANOLDODECANAMIDE; DODECANAMIDE, N,N-BIS (2-HYDROXYETHYL) -; LAURIC ACID DIETHANOLAMIDE; LAURIC DIETHANOLAMIDE; LAUROYL DIETHAN OLAMIDE; N,N-BIS (2-HYDROXYETHYL) - DODECANAMIDE; DODECANAMIDE, N,NBIS (2HYDROXYETHYL) ; LAURIC DIETHANOLAMIDE; LAURIC DIETHANOLAMIDE
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
 | Violations, restrictions & warnings |
| Allergies/immunotoxicity |
 | Contamination concerns - NITROSAMINES |
| Other moderate concerns for this ingredient: Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| Lesser or emerging concerns for this ingredient: Ecotoxicology, Data gaps, Biochemical or cellular level changes |
|
See products containing LAURAMIDE DEA | |
About LAURAMIDE DEA: Lauramide DEA is a mixture of ethanolamides of lauric acid. It conforms generally to theformula:
LAURAMIDE DEA has reported used in the following product types: shampoo (91); facial cleanser (45); body wash/cleanser (43); liquid hand soap (40); hair relaxer (38); hair color and bleaching (30); bubble bath (15); dandruff/scalp treatment (14); acne treatment (14); styling mousse/foam (9)
Cancer
| type of concern | product conditions | reference |
| Possible carcinogen | Environmental Canada Domestic Substance List | |
| show more | ||
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Classified as a high human health priority | Environmental Canada Domestic Substance List | |
| Classified as expected to be toxic or harmful | Environmental Canada Domestic Substance List | |
| show more | ||
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environmental Canada Domestic Substance List |
Violations, restrictions & warnings
| type of concern | product conditions | reference |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Cosmetic Ingredient Review Assessments |
Biochemical or cellular level changes
| type of concern | product conditions | reference |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | RTECS®- Journal of the American College of Toxicology 1986 |
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| One or more animal studies show skin irritation at very low doses | RTECS®- Journal of the American College of Toxicology 1986 | |
| show more | ||
Ecotoxicology
| type of concern | product conditions | reference |
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environmental Canada Domestic Substance List | |
| show more | ||
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Data gaps
| type of concern | product conditions | reference |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments | |
| 359 studies on toxicity in PubMed see search results -> | PubMed |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Cosmetic Ingredient Review Assessments | LAURAMIDE DEA | •Safe for use in cosmetics with some qualifications •Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product •Amine: forms carcinogenic nitrosamine compounds if mixed with nitrosating agents •May contain harmful impurities |
| FDA Everything Added to Food | LAUROYL DIETHANOLAMIDE | • Fully up-to-date toxicology information has been sought. |
| Environmental Canada Domestic Substance List | DODECANAMIDE, N,N-BIS(2-HYDROXYETHYL)- | •This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. |
| RTECS®- Journal of the American College of Toxicology 1986 | LAURAMIDE DEA | • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) |
| RTECS®- Journal of the American College of Toxicology 1986 | LAURAMIDE DEA | • blood - Changes in serum composition (eg., TP, bilirubin, cholesterol) (rat TDLo) • sense organ - Primary eye irritant (rabbit ) • skin - Primary skin irritant (rabbit ) • biochemical - Transaminases (rat TDLo) |
| RTECS®- Journal of the Society of Cosmetic Chemists 1962 | LAURAMIDE DEA | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- National Technical Information Service 9989 | LAURAMIDE DEA | • cancer - liver tumor formations - equivocal (mouse TDLo) |
| RTECS®- National Toxicology Program Technical Report Series 1999 | LAURAMIDE DEA | • kidney or renal system - Changes in kidney weight (mouse TDLo) • skin - Dermatitis, other (rat TDLo) • cancer - liver tumors (mouse TDLo) |
references
| government/industry list/academic study | reference |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| RTECS®- Journal of the American College of Toxicology 1986 | RTECS®- Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. 5(5),415,1986 |
| RTECS®- Journal of the American College of Toxicology 1986 | RTECS®- Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. 5(5),415,1986 |
| RTECS®- Journal of the Society of Cosmetic Chemists 1962 | RTECS®- Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947- 13,469,1962 |
| RTECS®- National Technical Information Service 9989 | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. PB99-169989 |
| RTECS®- National Toxicology Program Technical Report Series 1999 | RTECS®- National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- NTP-TR-480,1999 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
All rights reserved.
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