PPG-2 METHYL ETHER
Fragrance Ingredient; Solvent
Also listed as
DIPROPYLENE GLYCOL MONOMETHYL ETHER; METHOXY DIPROPYLENE GLYCOL; (2-METHOXYMETHYLETHOXY) PROPANOL; 1- (2-METHOXYPROPOXY) -2-PROPANOL; POLYOXYPROPYLENE (2) METHYL ETHER; POLYPROPYLENE GLYCOL (2) ME THYL ETHER; PROPANOL, (2-METHOXYMETHYLETHOXY) -; (2-METHOXYMETHYLETHOXY) - PROPANOL; 1- (2-METHOXYPROPOXY) - 2-PROPANOL; PROPANOL, 1 (OR 2) (2METHOXYMETHYLETHOXY) ; 1,4-DIMETHYL-3,6-DIOXA-1-HEPTANOL
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
| Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive), Occupational hazards |
 | Lesser or emerging concerns for this ingredient: Irritation (skin, eyes, or lungs), Data gaps |
|
See products containing PPG-2 METHYL ETHER | |
About PPG-2 METHYL ETHER: PPG-2 Methyl Ether is the polypropylene glycol ether of methyl alcohol that conforms to theformula: where n has an average value of 2.
PPG-2 METHYL ETHER has reported used in the following product types: conditioner (12); styling gel/lotion (1)
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| Limited evidence of reproductive toxicity | National Library of Medicine HazMap |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Classified as expected to be toxic or harmful | Environmental Canada Domestic Substance List | |
| show more | ||
Occupational hazards
| type of concern | product conditions | reference |
| Allowed workplace exposures restricted to high doses | RTECS®- TLV/BEI,2006 | |
| show more | ||
Irritation (skin, eyes, or lungs)
| type of concern | product conditions | reference |
| One or more animal studies show skin irritation at moderate doses | RTECS®- Union Carbide Data Sheet 1971 |
Neurotoxicity
| type of concern | product conditions | reference |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 9 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Association of Occupational and Environmental Clinics | PROPYLENE GLYCOL ETHERS | • S |
| Environmental Canada Domestic Substance List | PROPANOL, 1(OR 2)-(2-METHOXYMETHYLETHOXY)- | •This chemical was deemed a moderate human health priority and was flagged by CEPA for further attention. |
| IFRA Fragrance Ingredient List | DIPROPYLENE GLYCOL MONOMETHYL ETHER | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| National Library of Medicine HazMap | DIPROPYLENE GLYCOL METHYL ETHER | •Skin Designation (ACGIH) - Danger of cutaneous absorption (ACGIH): Yes; •Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male and female reproductive function: Yes; •Nephrotoxin: Yes; •Neurotoxin: CNS Solvent Syndrome; •PEL (OSHA) - Permissible exposure limit (OSHA): 100 ppm; •STEL (ACGIH) - Short-term exposure limits (ACGIH): 150 ppm; •TLV (ACGIH) - Threshold limit value (ACGIH): 100 ppm; •IDLH (NIOSH) - Immediately Dangerous to Life or Health: 600 ppm; •Odor Threshold Low - The lowest concentration at which a substance can be detected or recognized using the sense of smell: 1000 ppm; •MAK - Maximum Allowable Concentration (Federal Republic of Germany): 50 ppm, mixture of isomers; |
| EPA Categorized List of Inert Pesticide Ingredients | DIPROPYLENE GLYCOL MONOMETHYL ETHER | •Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency) |
| RTECS®- TLV/BEI,2006 | PPG-2 METHYL ETHER | • occupationally related - ACGIH TLV (human TWA) |
| RTECS®- TLV/BEI,2007 | PPG-2 METHYL ETHER | • occupationally related - ACGIH TLV (human TWA) |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | PPG-2 METHYL ETHER | • sense organ - Primary eye irritant (rabbit ) |
| RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology 1984 | PPG-2 METHYL ETHER | • sense organ - Primary eye irritant ( human ) |
| RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology 1984 | PPG-2 METHYL ETHER | • sense organ - Primary eye irritant ( human ) |
| RTECS®- MSHA STANDARD-air: 3,96,1971 | PPG-2 METHYL ETHER | • occupationally related - MSHA STANDARD-air (human TWA) |
| RTECS®- OSHA PEL (Construc): 29,1926 1994 | PPG-2 METHYL ETHER | • occupationally related - OSHA PEL (Construc) (human TWA) |
| RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994 | PPG-2 METHYL ETHER | • occupationally related - OSHA PEL (Fed Cont) (human TWA) |
| RTECS®- OSHA PEL (Gen Indu): 29,1910 1994 | PPG-2 METHYL ETHER | • occupationally related - OSHA PEL (Gen Indu) (human TWA) |
| RTECS®- OSHA PEL (Shipyard): 29,1915 1993 | PPG-2 METHYL ETHER | • occupationally related - OSHA PEL (Shipyard) (human TWA) |
| RTECS®- Union Carbide Data Sheet 1971 | PPG-2 METHYL ETHER | • skin - Primary skin irritant (rabbit ) |
references
| government/industry list/academic study | reference |
| Association of Occupational and Environmental Clinics | AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| EPA Categorized List of Inert Pesticide Ingredients | EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients. |
| RTECS®- TLV/BEI,2006 | RTECS®- TLV/BEI,2006 |
| RTECS®- TLV/BEI,2007 | RTECS®- TLV/BEI,2007 |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,633,1986 |
| RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology 1984 | RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1982- 2,229,1983/1984 |
| RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology 1984 | RTECS®- Journal of Toxicology, Cutaneous and Ocular Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 2,229,1983/1984 |
| RTECS®- MSHA STANDARD-air: 3,96,1971 | RTECS®- MSHA STANDARD-air: 3,96,1971 |
| RTECS®- OSHA PEL (Construc): 29,1926 1994 | RTECS®- OSHA PEL (Construc): 29,1926.55,1994 |
| RTECS®- OSHA PEL (Fed Cont): 41,50-204 1994 | RTECS®- OSHA PEL (Fed Cont): 41,50-204.50,1994 |
| RTECS®- OSHA PEL (Gen Indu): 29,1910 1994 | RTECS®- OSHA PEL (Gen Indu): 29,1910.1000,1994 |
| RTECS®- OSHA PEL (Shipyard): 29,1915 1993 | RTECS®- OSHA PEL (Shipyard): 29,1915.1000,1993 |
| RTECS®- Union Carbide Data Sheet 1971 | RTECS®- Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) 11/15/1971 |
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