PPG-3 METHYL ETHER || Skin Deep: Cosmetic Safety Reviews

PPG-3 METHYL ETHER

Solvent

SCORE

	1	low hazard
	89%	data gap
(why scores have changed)

Also listed as

POLYOXYPROPYLENE (3) METHYL ETHER; POLYPROPYLENE GLYCOL (3) METHYL ETHER; TRIPROPYLENE GLYCOL MONOMETHYL ETHER; [2- (2-METHOXYMETHYLETHOXY) METHYLETHOXY] PROPANOL; PROPANOL, [2 (2METHOXYMETHYLETHOXY) METHYLETHOXY] ; (2- (2-METHOXYMETHYLETHOXY) METHYLETHOXY) PROPANOL; ARCOSOLV TPM; DOWANOL 62B; DOWANOL TPM; DOWANOL TPM GLYCOL ETHER; O-METHYLTRIPROPYLENE GLYCOL

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive)
	Lesser or emerging concerns for this ingredient: Data gaps
	See products containing PPG-3 METHYL ETHER

About PPG-3 METHYL ETHER: PPG-3 Methyl Ether is the polypropylene glycol ether of methyl alcohol that conforms to theformula: where n has an average value of 3.

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show sense organ effects at low doses

products for use around the eyes, mouth, or lips

RTECS^®- National Technical Information Service 4581

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be bioaccumulative

Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Environmental Canada Domestic Substance List	PROPANOL, [2-(2-METHOXYMETHYLETHOXY)METHYLETHOXY]-	•This chemical was NOT flagged by CEPA for further attention.
IFRA Fragrance Ingredient List	PROPANOL, [2-(2-METHOXYMETHYLETHOXY)METHYLETHOXY]-	•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
EPA Categorized List of Inert Pesticide Ingredients	TRIPROPYLENE GLYCOL MONOMETHYL ETHER	•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
EPA Categorized List of Inert Pesticide Ingredients	[2-(2- METHOXYMETHYLETHOXY)METHYLETHOXY]PROPANOL	•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
RTECS^®- Dow Chemical Company Reports	PPG-3 METHYL ETHER	• broad systemic - Broad systemic toxicity (rat LD50)
RTECS^®- National Technical Information Service 4581	PPG-3 METHYL ETHER	• sense organ - Primary eye irritant (rabbit )

references

government/industry list/academic study	reference
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient List	IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Categorized List of Inert Pesticide Ingredients	EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
RTECS^®- Dow Chemical Company Reports	RTECS^®- Dow Chemical Company Reports. (Dow Chemical USA, Health and Environment Research, Toxicology Research Lab., Midland, MI 48640) MSD-53
RTECS^®- National Technical Information Service 4581	RTECS^®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0534581

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