PROPYLENE GLYCOL ALGINATE || Skin Deep: Cosmetic Safety Reviews

PROPYLENE GLYCOL ALGINATE

Binder; Fragrance Ingredient; Viscosity Increasing Agent - Aqueous; BINDING; VISCOSITY CONTROLLING

SCORE

	1	low hazard
	89%	data gap
(why scores have changed)

Also listed as

ALGINIC ACID, ESTER WITH 1,2-PROPANEDIOL; ESTER WITH 1,2-PROPANEDIOL ALGINIC ACID; ALGINIC ACID, ESTER WITH 1,2PROPANEDIOL; KELCOLOID

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Other moderate concerns for this ingredient: Organ system toxicity (non-reproductive)
	Lesser or emerging concerns for this ingredient: Data gaps
	See products containing PROPYLENE GLYCOL ALGINATE

About PROPYLENE GLYCOL ALGINATE: Propylene Glycol Alginate is a mixture of the propylene glycol esters of alginic acid.

PROPYLENE GLYCOL ALGINATE has reported used in the following product types: anti-aging (2); facial moisturizer/treatment (2); mouthwash (1); sunless tanning (1); acne treatment (1)

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

Classified as medium human health priority

Environmental Canada Domestic Substance List

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel
10 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Multiple, additive exposure sources

type of concern	product conditions	reference
Designated as safe for general or specific, limited use in food		FDA Food Additive Status
Designated as safe for general or specific, limited use in food		FDA Everything Added to Food

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
FDA Food Additive Status	PROPYLENE GLYCOL ALGINATE	• miscellaneous • Food additive: food additive for which a petition has been filed and a regulation issued • stab less than 0.5% by weight in frozen dairy desserts • emul/stab/or thickener less than 0.5% by weight in baked goods • emul/stab/thickener <0.9% by weight in cheeses • in - refers to part number under Title 21 Code of Federal Regulations 135 • Frozen Desserts • refers to part number under Title 21 Code of Federal Regulations 166 Marg • Food additive: food additive for which a petition has been filed and a regulation issued • Food additive: must be in accordance with good manufacturing practices, or sufficient for purpose; or in quantity not greater than required • In processing foods - CFR172.858 • Food additive: permitted as optional ingredient in a standardized food • refers to part number under Title 21 Code of Federal Regulations 133 • Ch
FDA Everything Added to Food	PROPYLENE GLYCOL ALGINATE	• Fully up-to-date toxicology information has been sought.
Environmental Canada Domestic Substance List	ALGINIC ACID, ESTER WITH 1,2-PROPANEDIOL	•This chemical was deemed a moderate human health priority even though it did not meet the strict criteria of the categorization exercise of CEPA. The chemical was flagged for uncertain bioaccumulation and uncertain persistence.
IFRA Fragrance Ingredient List	ALGINIC ACID, ESTER WITH 1,2-PROPANEDIOL	•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
RTECS^®- Food & Drug Research Laboratories, Inc 1976	PROPYLENE GLYCOL ALGINATE	• broad systemic - Broad systemic toxicity (hamster LD50)

references

government/industry list/academic study	reference
FDA Food Additive Status	FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient List	IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
RTECS^®- Food & Drug Research Laboratories, Inc 1976	RTECS^®- Food & Drug Research Laboratories, Inc., Papers. (P.O. Box 107, Rt. 17C, Waverly, NY 14892-0107) 124,-,1976

"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.