PROPYLENE GLYCOL METHYL ETHER ACETATE || Skin Deep: Cosmetic Safety Reviews

PROPYLENE GLYCOL METHYL ETHER ACETATE

Solvent

SCORE

	1	low hazard
	81%	data gap
(why scores have changed)

Also listed as

METHOXYISOPROPYL ACETATE, 2-METHOXY-1-METHYLETHYL ACETATE; PROPYLENE GLYCOL MONOMETHYL ETHER ACETATE; 2PROPANOL, 1METHOXY, ACETATE; 1-METHOXY-2-ACETOXYPROPANE; 1-METHOXY-2-PROPYL ACETATE; 2-PROPANOL, 1-METHOXY-, ACETATE (9CI) ; DOWANOL (R) PMA GLYCOL ETHER ACETATE; PGMEA; PROPYLENE GLYCOL MONOMETHYL ACETATE; PROPYLENE GLYCOL MONOMETHYL ETHER ACETATE; PROPYLENEGLYCOL MONOMETHYL ETHER ACETATE

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Lesser or emerging concerns for this ingredient: Organ system toxicity (non-reproductive), Occupational hazards
	See products containing PROPYLENE GLYCOL METHYL ETHER ACETATE

About PROPYLENE GLYCOL METHYL ETHER ACETATE: Methoxyisopropyl Acetate is the organic compound.

PROPYLENE GLYCOL METHYL ETHER ACETATE has reported used in the following product types: eyelash glue (1)

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)

RTECS^®- National Technical Information Service

Data gaps

type of concern	product conditions	reference
7 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Miscellaneous

type of concern	product conditions	reference
Occupational hazards related to handling		European Union - Classification & Labelling

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be persistent

Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
European Union - Classification & Labelling	2-METHOXY-1-METHYLETHYL ACETATE	•Flammable
Environmental Canada Domestic Substance List	2-PROPANOL, 1-METHOXY-, ACETATE	•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged for as a low human health priority.
RTECS^®- Dow Chemical Company Reports 1582	PROPYLENE GLYCOL METHYL ETHER ACETATE	• broad systemic - Broad systemic toxicity (rat LD50)
RTECS^®- National Technical Information Service	PROPYLENE GLYCOL METHYL ETHER ACETATE	• broad systemic - Broad systemic toxicity (mouse LD50)

references

government/industry list/academic study	reference
European Union - Classification & Labelling	CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS^®- Dow Chemical Company Reports 1582	RTECS^®- Dow Chemical Company Reports. (Dow Chemical USA, Health and Environment Research, Toxicology Research Lab., Midland, MI 48640) MSD-1582
RTECS^®- National Technical Information Service	RTECS^®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. AD691-490

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