SODIUM SACCHARIN
Flavoring Agent; Fragrance Ingredient; MASKING; ORAL CARE
Also listed as
1,2-BENZISOTHIAZOL-3 (2H) -ONE, 1,1-DIOXIDE, SODIUM SALT, DIHYDRATE; O-BENZOYLSULFIMIDE SODIUM SALT; CRYSTALLOSE; 1,1-DIOXIDE-1,2-BENZISOTHIAZOL-3 (2H) -ONE, SODIUM SALT, DIHYDRATE; SACCHARINE, SODIUM SALT; SACCHARIN SODIUM; SODUIM SA CCHARINE; DIHYDRATE 1,2-BENZISOTHIAZOL-3 (2H) -ONE, 1,1-DIOXIDE, SODIUM SALT; DIHYDRATE 1,1-DIOXIDE-1,2-BENZISOTHIAZOL-3 (2H) -ONE, SODIUM SALT; SODIUM SALT SACCHARINE; SODIUM SALT DIHYDRATE 1,2-BENZISOTHIAZOL-3 (2H) -ONE, 1,1-DIOXIDE
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
| Developmental/reproductive toxicity |
 | Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
 | Other moderate concerns for this ingredient: Neurotoxicity |
| Lesser or emerging concerns for this ingredient: Endocrine disruption, Organ system toxicity (non-reproductive), Data gaps |
|
See products containing SODIUM SACCHARIN | |
About SODIUM SACCHARIN: Sodium Saccharin is the organic compound.
SODIUM SACCHARIN has reported used in the following product types: toothpaste (503); tooth whitening (258); mouthwash (130); lip gloss (118); lip plumper (59); lipstick (55); lip balm (53); oral pain relief (46); sunscreen: lip balm (26); breath fresheners (17)
Neurotoxicity
| type of concern | product conditions | reference |
| One or more animal studies show brain and nervous system effects at very low doses | RTECS®- Journal of Pharmacology and Experimental Therapeutics 2002 | |
| show more | ||
Cancer
| type of concern | product conditions | reference |
| One or more in vitro tests on mammalian cells show positive mutation results | RTECS®- Mutation Research 1987 | |
| show more | ||
Endocrine disruption
| type of concern | product conditions | reference |
| One or more animal studies show endocrine system disruption at high doses | RTECS®- National Technical Information Service |
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| One or more animal studies show reproductive effects at high doses | RTECS®- Food and Chemical Toxicology 1988 | |
| show more | ||
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| One or more animal studies show broad systemic effects at high doses (low dose studies may be unavailable for this ingredient) | RTECS®- Food and Cosmetics Toxicology 1968 | |
| show more | ||
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 267 studies on toxicity in PubMed see search results -> | PubMed |
Ecotoxicology
| type of concern | product conditions | reference |
| Not suspected to be an environmental toxin | Environmental Canada Domestic Substance List |
Persistence and bioaccumulation
| type of concern | product conditions | reference |
| Not suspected to be persistent | Environmental Canada Domestic Substance List | |
| show more | ||
Multiple, additive exposure sources
| type of concern | product conditions | reference |
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status | |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| FDA Food Additive Status | SACCHARIN | • Food additive: non-nutritive sweetener • REG/ITEM • less than 12 milligram(s) /fl oz - In bevs and fruit juice drinks and bases or mixes - CFR180.37 • less than 20 mg/teaspoonful of sugar sweetening equivalency - In sugar substitutes for cooking or table use - CFR180.37 • less than 30 mg/serving - In processed foods -180.37 • refers to part number under Title 21 Code of Federal Regulations 145 |
| FDA Everything Added to Food | SACCHARIN, SODIUM SALT | • Fully up-to-date toxicology information has been sought. |
| Environmental Canada Domestic Substance List | 1,2-BENZISOTHIAZOL-3(2H)-ONE, 1,1-DIOXIDE, SODIUM SALT | •This chemical was NOT flagged by CEPA for further attention. |
| IFRA Fragrance Ingredient List | SACCHARINE, SODIUM SALT | •The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008. |
| RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale 1980 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Damage (mouse ipr) |
| RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale 1980 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Damage (mouse ipr) |
| RTECS®- British Journal of Cancer 1979 | SODIUM SACCHARIN | • kidney or renal system - Changes in blood vessels or in circulation of kidney (rat TD) • cancer - kidney or renal system tumor formations - equivocal (rat TD) |
| RTECS®- Bulletin of Environmental Contamination and Toxicology 1974 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse ipr) • mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse ipr) |
| RTECS®- Bulletin of Environmental Contamination and Toxicology 1974 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (mouse ipr) • mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse ipr) |
| RTECS®- Cancer Letters (Shannon, Ireland) 1986 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl) |
| RTECS®- Cancer Letters (Shannon, Ireland) 1986 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat orl) |
| RTECS®- Cancer Research 1977 | SODIUM SACCHARIN | • cancer - kidney or renal system neoplasms (rat TD) • mutagenic - skin neoplasms (rat TD) |
| RTECS®- Cancer Research 1980 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr) |
| RTECS®- Cancer Research 1980 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Unscheduled DNA Synthesis (rat lvr) |
| RTECS®- Chemico-Biological Interactions 1975 | SODIUM SACCHARIN | • cancer - kidney or renal system tumor formations - equivocal (rat TD) |
| RTECS®- Environmental Mutagenesis 1979 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Sister Chromatid Exchange ( human leu) |
| RTECS®- Food and Chemical Toxicology 1988 | SODIUM SACCHARIN | • reproductive - Growth statistics (rat TDLo) |
| RTECS®- Food and Chemical Toxicology 1991 | SODIUM SACCHARIN | • reproductive - Growth statistics (rat TDLo) |
| RTECS®- Food and Cosmetics Toxicology 1968 | SODIUM SACCHARIN | • broad systemic - Broad systemic toxicity (rat LD50) |
| RTECS®- Gann 1983 | SODIUM SACCHARIN | • cancer - kidney or renal system tumors (rat TDLo) |
| RTECS®- Hereditas (Lund, Sweden) 1972 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng) |
| RTECS®- Hereditas (Lund, Sweden) 1972 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster lng) |
| RTECS®- Indian Journal of Medical Research 1972 | SODIUM SACCHARIN | • reproductive - Fetal death (mouse TDLo) |
| RTECS®- Journal of Environmental Pathology and Toxicology 1979 | SODIUM SACCHARIN | • reproductive - Male fertility index (mouse TDLo) |
| RTECS®- Journal of Pharmacology and Experimental Therapeutics 2002 | SODIUM SACCHARIN | • brain and nervous system - Changes in psychophysiological tests (monkey TDLo) |
| RTECS®- Journal of Toxicological Sciences 1981 | SODIUM SACCHARIN | • metabolic - Weight loss or decreased weight gain (rat TDLo) • kidney or renal system - Other changes (rat TDLo) • kidney or renal system - Other changes in urine composition (rat TDLo) |
| RTECS®- Mutation Research 1987 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Inhibition ( human fbr) |
| RTECS®- Mutation Research 1988 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells ( human emb) |
| RTECS®- Mutation Research 1975 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: Cytogenetic Analysis ( human leu) • mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse orl) • mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Drosophila melanogaster par) • mutagenic - Positive mutation assay: sperm (mouse ipr) |
| RTECS®- Mutation Research 1977 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr) |
| RTECS®- Mutation Research 2002 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Damage (mouse orl) |
| RTECS®- Mutation Research 2004 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Morphological Transform (mouse oth) |
| RTECS®- Mutation Research 1979 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym) |
| RTECS®- Mutation Research 1979 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae ) |
| RTECS®- Mutation Research 1987 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Inhibition ( human fbr) |
| RTECS®- Mutation Research 1988 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Mammalian Somatic Cells ( human emb) |
| RTECS®- Mutation Research 1975 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium ) • mutagenic - Positive mutation assay: Cytogenetic Analysis ( human leu) • mutagenic - Positive mutation assay: Dominant Lethal Strain (mouse orl) • mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Drosophila melanogaster par) • mutagenic - Positive mutation assay: sperm (mouse ipr) |
| RTECS®- Mutation Research 1977 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Cytogenetic Analysis (hamster fbr) |
| RTECS®- Mutation Research 2002 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: DNA Damage (mouse orl) |
| RTECS®- Mutation Research 2004 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Morphological Transform (mouse oth) |
| RTECS®- Mutation Research 1979 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (mouse lym) |
| RTECS®- Mutation Research 1979 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Mutation in Micro-organism (Saccharomyces cerevisiae ) • mutagenic - Positive mutation assay: Gene Conversion and Mitotic Recombination (Saccharomyces cerevisiae ) |
| RTECS®- National Technical Information Service | SODIUM SACCHARIN | • reproductive - Behavioral (mouse TDLo) • endocrine system - Death in the "U" data type field (mouse TDLo) • reproductive - Live birth index (mouse TDLo) • brain and nervous system - Fluid intake (mouse TDLo) |
| RTECS®- Science of Biology Journal 1975 | SODIUM SACCHARIN | • mutagenic - Positive mutation assay: Sex Chromosome Loss and Nondisjunction (Drosophila melanogaster orl) |
| RTECS®- Science 1970 | SODIUM SACCHARIN | • cancer - kidney or renal system neoplasms (mouse TDLo) • cancer - Tumors at site of application (mouse TDLo) |
| RTECS®- Toxicology and Applied Pharmacology 1980 | SODIUM SACCHARIN | • cancer - kidney or renal system tumors (rat TD) |
| RTECS®- Toxicology Letters 1983 | SODIUM SACCHARIN | • reproductive - Male fertility index (mouse TDLo) |
| RTECS®- Toxicology Letters 1981 | SODIUM SACCHARIN | • immune system - Decrease in humoral immune response (rat TDLo) |
| RTECS®- United States Patent Document 9913 | SODIUM SACCHARIN | • broad systemic - Broad systemic toxicity (mouse LD50) |
| RTECS®- Yakkyoku 1981 | SODIUM SACCHARIN | • broad systemic - Broad systemic toxicity (rabbit LDLo) |
references
| government/industry list/academic study | reference |
| FDA Food Additive Status | FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environmental Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale 1980 | RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 56,2486,1980 |
| RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale 1980 | RTECS®- Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 1927- 56,2486,1980 |
| RTECS®- British Journal of Cancer 1979 | RTECS®- British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- 39,355,1979 |
| RTECS®- Bulletin of Environmental Contamination and Toxicology 1974 | RTECS®- Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- 12,186,1974 |
| RTECS®- Bulletin of Environmental Contamination and Toxicology 1974 | RTECS®- Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 12,186,1974 |
| RTECS®- Cancer Letters (Shannon, Ireland) 1986 | RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 33,119,1986 |
| RTECS®- Cancer Letters (Shannon, Ireland) 1986 | RTECS®- Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- 33,119,1986 |
| RTECS®- Cancer Research 1977 | RTECS®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- 37,2943,1977 |
| RTECS®- Cancer Research 1980 | RTECS®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- 40,4541,1980 |
| RTECS®- Cancer Research 1980 | RTECS®- Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 40,4541,1980 |
| RTECS®- Chemico-Biological Interactions 1975 | RTECS®- Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- 11,225,1975 |
| RTECS®- Environmental Mutagenesis 1979 | RTECS®- Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. 1,177,1979 |
| RTECS®- Food and Chemical Toxicology 1988 | RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 26,899,1988 |
| RTECS®- Food and Chemical Toxicology 1991 | RTECS®- Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- 29,657,1991 |
| RTECS®- Food and Cosmetics Toxicology 1968 | RTECS®- Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. 6,313,1968 |
| RTECS®- Gann 1983 | RTECS®- Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. 74,8,1983 |
| RTECS®- Hereditas (Lund, Sweden) 1972 | RTECS®- Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 1947- 70,271,1972 |
| RTECS®- Hereditas (Lund, Sweden) 1972 | RTECS®- Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 70,271,1972 |
| RTECS®- Indian Journal of Medical Research 1972 | RTECS®- Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- 60,599,1972 |
| RTECS®- Journal of Environmental Pathology and Toxicology 1979 | RTECS®- Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. 2(4),1047,1979 |
| RTECS®- Journal of Pharmacology and Experimental Therapeutics 2002 | RTECS®- Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- 301,993,2002 |
| RTECS®- Journal of Toxicological Sciences 1981 | RTECS®- Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- 6,246,1981 |
| RTECS®- Mutation Research 1987 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 183,89,1987 |
| RTECS®- Mutation Research 1988 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 209,13,1988 |
| RTECS®- Mutation Research 1975 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 32,81,1975 |
| RTECS®- Mutation Research 1977 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 48,337,1977 |
| RTECS®- Mutation Research 2002 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 519,103,2002 |
| RTECS®- Mutation Research 2004 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 557,191,2004 |
| RTECS®- Mutation Research 1979 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 59,61,1979 |
| RTECS®- Mutation Research 1979 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 67,215,1979 |
| RTECS®- Mutation Research 1987 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 183,89,1987 |
| RTECS®- Mutation Research 1988 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 209,13,1988 |
| RTECS®- Mutation Research 1975 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 32,81,1975 |
| RTECS®- Mutation Research 1977 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 48,337,1977 |
| RTECS®- Mutation Research 2002 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 519,103,2002 |
| RTECS®- Mutation Research 2004 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 557,191,2004 |
| RTECS®- Mutation Research 1979 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 59,61,1979 |
| RTECS®- Mutation Research 1979 | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 67,215,1979 |
| RTECS®- National Technical Information Service | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. #PB85188258/AS |
| RTECS®- Science of Biology Journal 1975 | RTECS®- Science of Biology Journal. (Springfield, IL) V.1-4, 1975-78(?). Discontinued. 1,77,1975 |
| RTECS®- Science 1970 | RTECS®- Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- 168,1238,1970 |
| RTECS®- Toxicology and Applied Pharmacology 1980 | RTECS®- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- 52,113,1980 |
| RTECS®- Toxicology Letters 1983 | RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 19,267,1983 |
| RTECS®- Toxicology Letters 1981 | RTECS®- Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- 8,1,1981 |
| RTECS®- United States Patent Document 9913 | RTECS®- United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) #4869913 |
| RTECS®- Yakkyoku 1981 | RTECS®- Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- 32,1367,1981 |
"RTECS®" is a United States trademark owned and licensed under authority of the U.S. Government, by and through MDL Information Systems, Inc.
Copyright © 2010 by Environmental Working Group
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