TALLOWTRIMONIUM CHLORIDE || Skin Deep: Cosmetic Safety Reviews

TALLOWTRIMONIUM CHLORIDE

Antistatic Agent; Hair Conditioning Agent; PRESERVATIVE; SURFACTANT

SCORE

	1	low hazard
	93%	data gap
(why scores have changed)

Also listed as

QUATERNARY AMMONIUM COMPOUNDS, TALLOW ALKYL TRIMETHYL, CHLORIDES; TALLOW TRIMETHYL AMMONIUM CHLORIDE; CHLORIDES QUATERNARY AMMONIUM COMPOUNDS, TALLOW ALKYL TRIMETHYL; TALLOW ALKYL TRIMETHYL CHLORIDES QUATERNARY AMMONIUM COMPOUNDS; N,N,N-TRIMETHYLTALLOWAMMONIUM CHLORIDE; QUATERNARY AMMONIUM COMPOUNDS, TRIMETHYLTALLOW ALKYL, CHLORIDES; TALLOWTRIMETHYLAMMONIUM CHLORIDE; TRIMETHYLTALLOWALKYLAMMONIUM CHLORIDE; TRIMETHYL (TALLOWALKYL) AMMONIUM CHLORIDE; (TALLOW) TRIMETHYLAMMONIUM CHLORIDE; ADOGEN 471; ARQUAD T; ARQUAD T-50

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Lesser or emerging concerns for this ingredient: Ecotoxicology, Data gaps
	See products containing TALLOWTRIMONIUM CHLORIDE

About TALLOWTRIMONIUM CHLORIDE: Tallowtrimonium Chloride is the quaternary ammonium salt that conforms generally to theformula: where R represents the alkyl groups derived from tallow.

This ingredient may be derived from animals. From PETA's Caring Consumer: Rendered beef fat. May cause eczema and blackheads. In wax paper, crayons, margarines, paints, rubber, lubricants, etc. In candles, soaps, lipsticks, shaving creams, other cosmetics. Chemicals (e.g., PCB) can be in animal tallow. Derivatives: Sodium Tallowate, Tallow Acid, Tallow Amide, Tallow Amine, Talloweth-6, Tallow Glycerides, Tallow Imidazoline. Alternatives: vegetable tallow, Japan tallow, paraffin and/or ceresin (see alternatives to Beeswax for all three). Paraffin is usually from petroleum, wood, coal, or shale oil.

TALLOWTRIMONIUM CHLORIDE has reported used in the following product types: conditioner (13); styling gel/lotion (3); shampoo (2); detangler (1); shaving cream (1); hair-loss treatment (1)

Cancer

type of concern	product conditions	reference
One or more in vitro tests non-mammalian cells show positive mutation results		RTECS^®- Bulletin of Environmental Contamination and Toxicology 1982

Ecotoxicology

type of concern	product conditions	reference
Suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

Classified as a low human health priority

Environmental Canada Domestic Substance List

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be bioaccumulative

Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
Environmental Canada Domestic Substance List	QUATERNARY AMMONIUM COMPOUNDS, TRIMETHYLTALLOW ALKYL, CHLORIDES	•This chemical was NOT flagged by CEPA for further attention. The chemical was flagged as a low human health priority and for suspected aquatic toxicity.
RTECS^®- Bulletin of Environmental Contamination and Toxicology 1982	TALLOWTRIMONIUM CHLORIDE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )
RTECS^®- Bulletin of Environmental Contamination and Toxicology 1982	TALLOWTRIMONIUM CHLORIDE	• mutagenic - Positive mutation assay: Mutation in Micro-organism (Salmonella typhimurium )

references

government/industry list/academic study	reference
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
RTECS^®- Bulletin of Environmental Contamination and Toxicology 1982	RTECS^®- Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- 28,33,1982
RTECS^®- Bulletin of Environmental Contamination and Toxicology 1982	RTECS^®- Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 28,33,1982

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