ALUMINUM SESQUICHLOROHYDREX PG
Antiperspirant Agent; Cosmetic Astringent; Deodorant Agent
Also listed as
ALUMINUM SESQUICHLOROHYDREX PROPYLENE GLYCOL COMPLEX
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
| Other moderate concerns for this ingredient: Neurotoxicity, Organ system toxicity (non-reproductive) |
 | Lesser or emerging concerns for this ingredient: Data gaps |
About ALUMINUM SESQUICHLOROHYDREX PG: Aluminum Sesquichlorohydrex PG is a coordination complex of AluminumSesquichlorohydrate (q.v.) and Propylene Glycol (q.v.) in which some of the water molecules normallycoordinated to the metal have been displaced by the propylene glycol. In t he United States, AluminumSesquichlorohydrex PG may be used as an active ingredient in OTC drug products. When used as anactive drug ingredient, the established name for Aluminum Sesquichlorohydrex PG is AluminumSesquichlorohydrex Propylene Glycol. See "Regulatory and Ingredient Use Information," regarding thelabeling names for U.S. OTC Drug Ingredients in Volume 1, Introduction, Part A.
Neurotoxicity
| type of concern | product conditions | reference |
| Strong evidence of human neurotoxicity | Chemicals known to be neurotoxic to humans |
Developmental/reproductive toxicity
| type of concern | product conditions | reference |
| Human nervous system toxicant - moderate evidence | Chemicals known to be neurotoxic to humans |
Organ system toxicity (non-reproductive)
| type of concern | product conditions | reference |
| Limited evidence of toxicity | products that may be aerosolized (airborne) | Klaassen, C |
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Chemicals known to be neurotoxic to humans | ALUMINUM COMPOUNDS | •Known to be neurotoxic to humans, suspected developmental neurotoxin |
| Klaassen, C | ALUMINUM COMPOUNDS | •Respiratory toxicity hazards: suspected |
references
| government/industry list/academic study | reference |
| Chemicals known to be neurotoxic to humans | Grandjean P and PJ Landrigan. 2006. Developmental neurotoxicity of industrial chemicals. Lancet. 2006 Dec 16;368(9553):2167-78. |
| Scorecard.org Toxicity Information | Klaassen, C., M. Amdur and J. Doull (eds.). Casarett and Doull |
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