PROPYLENE GLYCOL BUTYL ETHER || Skin Deep: Cosmetic Safety Reviews

PROPYLENE GLYCOL BUTYL ETHER

Fragrance Ingredient; Solvent; HUMECTANT; VISCOSITY CONTROLLING

SCORE

	1	low hazard
	86%	data gap
(why scores have changed)

Also listed as

BUTOXYISOPROPANOL; 3-BUTOXYPROPAN-2-OL; 2-PROPANOL, 1-BUTOXY-; PROPYLENE GLYCOL MONOBUTYL ETHER; 1-BUTOXY- 2-PROPANOL; 1-BUTOXY-2-PROPANOL; 1-BUTOXYPROPAN-2-OL; 2PROPANOL, 1BUTOXY2; 1-BUTOXY-2-PROPANOL; PROPASOL SOLVENT B; PROPYLENE GLYCOL N-BUTYL ETHER

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

This ingredient:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Contamination concerns
	Other strong concerns for this ingredient: Irritation (skin, eyes, or lungs)
	Lesser or emerging concerns for this ingredient: Organ system toxicity (non-reproductive), Data gaps

About PROPYLENE GLYCOL BUTYL ETHER: Propylene Glycol Butyl Ether is the propylene glycol ether of n-butyl alcohol that conforms tothe formula:

Irritation (skin, eyes, or lungs)

type of concern	product conditions	reference
Classified as irritant		European Union - Classification & Labelling

Organ system toxicity (non-reproductive)

type of concern

product conditions

reference

One or more animal studies show effects at moderate doses (low dose studies may be unavailable for this ingredient)

EPA Categorized List of Inert Pesticide Ingredients

Data gaps

type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel
6 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Ecotoxicology

type of concern	product conditions	reference
Not suspected to be an environmental toxin		Environmental Canada Domestic Substance List

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be bioaccumulative

Environmental Canada Domestic Substance List

Government, industry, academic studies and classifications

government/industry list/academic study	appears on list as	classification(s)
European Union - Classification & Labelling	3-BUTOXYPROPAN-2-OL	•Irritant (eyes, skin, or lungs) •Irritating to eyes and skin
Environmental Canada Domestic Substance List	2-PROPANOL, 1-BUTOXY-	•This chemical was NOT flagged by CEPA for further attention.
IFRA Fragrance Ingredient List	2-PROPANOL, 1-BUTOXY-	•The chemical has been reported as used in fragrance compounds by IFRA affiliated member companies in 2008.
EPA Categorized List of Inert Pesticide Ingredients	1- BUTOXY-2-PROPANOL	•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)
EPA Categorized List of Inert Pesticide Ingredients	PROPYLENE GLYCOL MONOBUTYL ETHER	•Pesticide inerts: potentially toxic, testing priority, according to EPA (Environmental Protection Agency)

references

government/industry list/academic study	reference
European Union - Classification & Labelling	CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Environmental Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient List	IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Categorized List of Inert Pesticide Ingredients	EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.

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