FULLERENE (C60 HYDROXIDE)
ANTIMICROBIAL; SKIN CONDITIONING
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to this ingredient -- not the products containing it -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
| This ingredient: | |
 | Cancer |
 | Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Contamination concerns |
 | Other strong concerns for this ingredient: Enhanced skin absorption |
 | Other moderate concerns for this ingredient: Biochemical or cellular level changes |
| Lesser or emerging concerns for this ingredient: Data gaps |
|
See products containing FULLERENE (C60 HYDROXIDE) | |
FULLERENE (C60 HYDROXIDE) has reported used in the following product types: facial moisturizer/treatment (1); skin fading/lightener (1); anti-aging (1)
Cancer
| type of concern | product conditions | reference |
| One or more in vitro tests on mammalian cells show positive mutation results | Dhawan A, Taurozzi JS, Pandey AK, Shan W, Miller SM, Hashsham SA, Tarabara VV, 2006 |
Biochemical or cellular level changes
| type of concern | product conditions | reference |
| One or more animal studies show changes at low doses where the human health implications are not yet well understood | Oberdorster E, 2004 |
Data gaps
| type of concern | product conditions | reference |
| Not assessed for safety in cosmetics by industry panel | ||
| 316 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | PubMed |
Enhanced skin absorption
| type of concern | product conditions | reference |
| Nano-scale ingredients with potential to absorb into the skin | Nanomaterial Database |
Government, industry, academic studies and classifications
| government/industry list/academic study | appears on list as | classification(s) |
| Nanomaterial Database | PURE FULLERENES | •nano-scale ingredient |
| Nanomaterial Database | FULLERENE-MIXTURE | •nano-scale ingredient |
| Dhawan A, Taurozzi JS, Pandey AK, Shan W, Miller SM, Hashsham SA, Tarabara VV, 2006 | C60 FULLERENES | Assay demonstrated genotoxicity with a strong correlation between the genotoxic response and nC60 concentration |
| Oberdorster E, 2004 | C60 | Significant lipid peroxidation was found in brains of largemouth bass after 48 hr of exposure to 0.5 ppm uncoated nC60. |
references
| government/industry list/academic study | reference |
| Nanomaterial Database | NanoWerk. 2007. Nanomaterial Database. Available online: http://www.nanowerk.com/phpscripts/n_dbsearch.php |
| Open scientific literature | Dhawan A, Taurozzi JS, Pandey AK, Shan W, Miller SM, Hashsham SA, Tarabara VV, 2006. "Stable colloidal dispersions of C60 fullerenes in water: evidence for genotoxicity." Environ Sci Technol. 2006 Dec 1;40(23):7394-401. |
| Open scientific literature | Oberdorster E, 2004. "Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass." Environ Health Perspect. 2004 Jul;112(10):1058-62. |
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