

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Occupational hazards |
Ingredients from packaging: ACTIVE INGREDIENTS: PER TUBE: SODIUM MONOFLUOROPHOSPHATE (.15%). INACTIVE INGREDIENTS: DICALCIUM PHOSPHATE DIHYDRATE, WATER, GLYCERIN, SORBITOL, SODIUM LAURYL SULFATE, CELLULOSE GUM, FLAVOR, TETRAPOTASSIUM PYROPHOSPHATE, SODIUM SACCHARIN.
Directions from packaging: Brush thoroughly at least twice a day, (best after meals), or as directed by a dentist or physician.For children between 2-6, use a pea sized amount and supervise child's brushing and rinsing to minimize swallowing.Children under 2, ask a dentist or physician.
Warnings from packaging: As with all fluoride toothpastes, keep out of the reach of children under 6 years of age. If you accidentally swallow more than used for brushing, seek professional assistance or contact a poison control center immediately.
| score | data gap | concerns | |
| SODIUM MONOFLUOROPHOSPHATE (Active Ingredient) | 6 | 69% | Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive), Occupational hazards |
| FLAVOR | 4 | 100% | Miscellaneous |
| SODIUM LAURYL SULFATE | 2 | 68% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs) |
| SODIUM SACCHARIN | 2 | 78% | Neurotoxicity |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| SORBITOL | 1 | 88% | none identified |
| TETRAPOTASSIUM PYROPHOSPHATE | 1 | 87% | none identified |
| CELLULOSE GUM | 1 | 80% | none identified |
| DICALCIUM PHOSPHATE DIHYDRATE | 0 | 100% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show tumor formation at high doses | CELLULOSE GUM | |
| One or more in vitro tests on mammalian cells show positive mutation results | SORBITOL, SODIUM SACCHARIN, SODIUM MONOFLUOROPHOSPHATE, SODIUM LAURYL SULFATE, GLYCERIN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | SODIUM SACCHARIN, SODIUM LAURYL SULFATE | |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN, CELLULOSE GUM | |
| Human nervous system toxicant - moderate evidence | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM LAURYL SULFATE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | TETRAPOTASSIUM PYROPHOSPHATE, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show brain and nervous system effects at very low doses | SODIUM SACCHARIN | |
| Strong evidence of human neurotoxicity | SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | SODIUM SACCHARIN, SODIUM LAURYL SULFATE, GLYCERIN |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show gastrointestinal effects at high doses (low dose studies may be unavailable for this ingredient) | TETRAPOTASSIUM PYROPHOSPHATE, SORBITOL, SODIUM SACCHARIN, CELLULOSE GUM | |
| One or more animal studies show broad systemic effects at low doses | SODIUM LAURYL SULFATE | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, SODIUM MONOFLUOROPHOSPHATE |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Ingredient not fully labeled - identity unknown | FLAVOR |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | GLYCERIN | |
| One or more animal studies show skin irritation at very low doses | SODIUM LAURYL SULFATE |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not assessed for safety in cosmetics by industry panel | TETRAPOTASSIUM PYROPHOSPHATE, FLAVOR | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CELLULOSE GUM | |
| Not assessed for safety in cosmetics by industry panel | SORBITOL, SODIUM SACCHARIN, SODIUM MONOFLUOROPHOSPHATE, GLYCERIN, DICALCIUM PHOSPHATE DIHYDRATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to low doses | SODIUM MONOFLUOROPHOSPHATE | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood | SODIUM LAURYL SULFATE | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CELLULOSE GUM, GLYCERIN |
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