

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: PURIFIED WATER, ACETAMIDE MEA, CETEARYL ALCOHOL, CETEARETH-20, CETYL ALCOHOL, SOLUBLE COLLAGEN, PROPYLENE GLYCOL, ISOSTEARYL ETHYLIMIDONIUM ETHOSULFATE, HENNA EXTRACT, PLACENTA EXTRACT, HEXYLENE GLYCOL, CITRIC ACID, IMIDAZOLIDINYL UREA, METHYLPARABEN, PROPYLPARABEN, FRAGRANCE, GLYCERINE, PHOSPHORIC ACID.
| score | data gap | concerns | |
| CETEARETH-20 | 5 | 71% | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE, ETHYLENE OXIDE, 1,4-DIOXANE) |
| FRAGRANCE | 8 | 100% | Neurotoxicity, Allergies/immunotoxicity, Miscellaneous |
| METHYLPARABEN | 8 | 65% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| PROPYLENE GLYCOL | 4 | 58% | Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption |
| PLACENTAL EXTRACT PLACENTA EXTRACT | 5 | 75% | Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Contamination concerns (PROGESTERONE, ESTROGEN, ESTRONE) |
| IMIDAZOLIDINYL UREA | 5 | 70% | Allergies/immunotoxicity, Contamination concerns (FORMALDEHYDE) |
| HEXYLENE GLYCOL | 4 | 67% | Allergies/immunotoxicity, Irritation (skin, eyes, or lungs) |
| PROPYLPARABEN | 4 | 82% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| CITRIC ACID | 4 | 72% | Violations, restrictions & warnings, Neurotoxicity, Organ system toxicity (non-reproductive) |
| PHOSPHORIC ACID | 2 | 80% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| ACETAMIDE MEA | 1 | 73% | Contamination concerns (ACETAMIDE MEA) |
| CETEARYL ALCOHOL | 0 | 93% | none identified |
| CETYL ALCOHOL | 1 | 87% | Irritation (skin, eyes, or lungs) |
| ISOSTEARYL ETHYLIMIDAZOLINIUM ETHOSULFATE ISOSTEARYL ETHYLIMIDONIUM ETHOSULFATE | 0 | 100% | none identified |
| LAWSONIA INERMIS (HENNA) EXTRACT | 0 | 100% | none identified |
| SOLUBLE COLLAGEN | 0 | 100% | none identified |
| WATER (PURIFIED) | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests on mammalian cells show positive mutation results | PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, GLYCERIN |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | PROPYLENE GLYCOL, GLYCERIN | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN |
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | PROPYLENE GLYCOL, CETEARETH-20, ACETAMIDE MEA | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | PLACENTAL EXTRACT, CITRIC ACID | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | HEXYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at high doses | PROPYLENE GLYCOL, GLYCERIN | |
| One or more animal studies show brain and nervous system effects at moderate doses | PHOSPHORIC ACID, METHYLPARABEN, CETEARETH-20 | |
| One or more animal studies show brain and nervous system effects at very low doses | CITRIC ACID | |
| Moderate evidence of human neurotoxicity | FRAGRANCE |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | PROPYLENE GLYCOL, HEXYLENE GLYCOL, GLYCERIN | |
| One or more studies show weak endocrine disruption | PLACENTAL EXTRACT, METHYLPARABEN | |
| Limited evidence of any disruption | PROPYLPARABEN |
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PROPYLENE GLYCOL | |
| Human skin toxicant - strong evidence | PROPYLPARABEN, METHYLPARABEN | |
| Known human immune system toxicant | IMIDAZOLIDINYL UREA, HEXYLENE GLYCOL, FRAGRANCE |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient) | PROPYLENE GLYCOL, HEXYLENE GLYCOL, IMIDAZOLIDINYL UREA, CETYL ALCOHOL, ACETAMIDE MEA | |
| One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient) | CETEARETH-20 | |
| Limited evidence of sense organ toxicity | PROPYLPARABEN, PHOSPHORIC ACID | |
| Potential risk of infectious disease - any | PLACENTAL EXTRACT | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN, CITRIC ACID | |
| Known human any toxicant | METHYLPARABEN |
*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Occupational hazards related to handling | PHOSPHORIC ACID | |
| Ingredient not fully labeled - identity unknown | FRAGRANCE |
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | PROPYLPARABEN |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | CITRIC ACID, GLYCERIN | |
| One or more animal studies show skin irritation at very low doses | CETYL ALCOHOL | |
| One or more animal studies show skin irritation at low doses | CETEARETH-20, METHYLPARABEN | |
| One or more animal studies show skin irritation at moderate doses | ACETAMIDE MEA | |
| Classified as irritant | HEXYLENE GLYCOL, PROPYLENE GLYCOL | |
| Human skin irritant - moderate evidence | PHOSPHORIC ACID |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | HEXYLENE GLYCOL, CETYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | SOLUBLE COLLAGEN | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | CETEARYL ALCOHOL | |
| Not assessed for safety in cosmetics by industry panel | GLYCERIN, ISOSTEARYL ETHYLIMIDAZOLINIUM ETHOSULFATE, LAWSONIA INERMIS (HENNA) EXTRACT, PHOSPHORIC ACID, CITRIC ACID, FRAGRANCE | |
| Safety assessment was based on related chemical | PROPYLENE GLYCOL | |
| Insufficient data to determine safety | PLACENTAL EXTRACT | |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | PROPYLPARABEN, METHYLPARABEN, IMIDAZOLIDINYL UREA |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN | |
| Allowed workplace exposures restricted to low doses | PHOSPHORIC ACID |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | CITRIC ACID, GLYCERIN, PROPYLENE GLYCOL | |
| Interferes with gene expresion | METHYLPARABEN |
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