

Compact for Safe Cosmetics
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Animal Testing Policy |


Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
![]() | Cancer |
![]() | Developmental/reproductive toxicity |
![]() | Violations, restrictions & warnings |
![]() | Allergies/immunotoxicity |
![]() | Other concerns for ingredients used in this product: Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
Ingredients from packaging: WATER, CALCIUM CARBONATE, GLYCERIN, SMECTITE CLAY, ALCOHOL, CALENDULA OFFICINALIS FLOWER EXTRACT, COMMIPHORA MYRRHA EXTRACT, XANTHAN GUM, FOENICULUM VULGARE (FENNEL) OIL, AMMONIUM GLYCYRRHIZATE (FROM LICORICE ROOT).
Directions from packaging: Apply a small amount of Calendula Toothpaste to a dry toothbrush, and brush over the teeth and gums for a thorough cleaning.
| score | data gap | concerns | |
| ETHANOL ALCOHOL | 5 | 72% | Cancer, Developmental/reproductive toxicity, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| COMMIPHORA MYRRHA (MYRRH) EXTRACT COMMIPHORA MYRRHA EXTRACT | 1 | 100% | Multiple, additive exposure sources |
| CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT CALENDULA OFFICINALIS FLOWER EXTRACT | 1 | 91% | none identified |
| FOENICULUM VULGARE (FENNEL) OIL | 1 | 88% | Irritation (skin, eyes, or lungs) |
| CALCIUM CARBONATE | 1 | 87% | Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| CLAY | 0 | 100% | none identified |
| XANTHAN GUM | 0 | 94% | none identified |
| WATER | 0 | 0% | innocuous |
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | FOENICULUM VULGARE (FENNEL) OIL, CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT | |
| One or more in vitro tests on mammalian cells show positive mutation results | GLYCERIN | |
| Cancer - limited evidence | ETHANOL |
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at moderate doses | GLYCERIN | |
| Limited evidence of reproductive toxicity | ETHANOL |
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | ETHANOL | |
| One or more animal studies show brain and nervous system effects at high doses | GLYCERIN |
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | GLYCERIN, ETHANOL |
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | FOENICULUM VULGARE (FENNEL) OIL | |
| One or more animal studies show sense organ effects at very low doses | products for use around the eyes, mouth, or lips | CALCIUM CARBONATE, ETHANOL |
| One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient) | CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN |
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | XANTHAN GUM, GLYCERIN, FOENICULUM VULGARE (FENNEL) OIL, ETHANOL, CALCIUM CARBONATE | |
| Used in food or as an additive with limited or no toxicity information available | COMMIPHORA MYRRHA (MYRRH) EXTRACT, ETHANOL |
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | GLYCERIN | |
| One or more animal studies show skin irritation at low doses | ETHANOL, CALCIUM CARBONATE | |
| One or more animal studies show skin irritation at very low doses | FOENICULUM VULGARE (FENNEL) OIL |
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Not assessed for safety in cosmetics by industry panel | GLYCERIN, XANTHAN GUM | |
| Insufficient data to determine safety | CALENDULA OFFICINALIS (POT MARIGOLD) FLOWER EXTRACT | |
| Not assessed for safety in cosmetics by industry panel | FOENICULUM VULGARE (FENNEL) OIL, ETHANOL, COMMIPHORA MYRRHA (MYRRH) EXTRACT, CLAY, CALCIUM CARBONATE |
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to high doses | ETHANOL | |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN, CALCIUM CARBONATE |
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | ETHANOL, GLYCERIN |
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