DERMALOGICA MULTIVITAMIN HAND & NAIL TREATMENT (2006 FORMULATION)
last updated: 05/01/06 brand: Dermalogica by International Dermal Institute, Inc., The
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COMPANY POLICIES
Compact for Safe Cosmetics
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Animal Testing Policy |
Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.
Ingredients in this product are linked to: | |
 | Cancer |
| Developmental/reproductive toxicity |
| Violations, restrictions & warnings |
| Allergies/immunotoxicity |
| Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation, Organ system toxicity (non-reproductive), Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes |
Ingredients from packaging: WATER (AQUA), CYCLOPENTASILOXANE, GLYCERIN, C16-17 ALKYL BENZOATE, DI-C12-15 ALKYL FUMARATE, STEARIC ACID, DIMETHICONE, SODIUM DIHYDROXYCETYL PHOSPHATE, EXTRACTS OF: ROSA CENTIFOLIA FLOWER, ALGAE, GLYCYRRHIZA GLABRA (LICORICE) ROOT, GINKGO BILOBA LEAF, VITIS VINIFERA (GRAPE) SEED, LUPINUS ALBUS SEED, SPIRULINA MAXIMA; TOCOPHERYL ACETATE, ASCORBYL PALMITATE, RETINOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, PANTHENOL, ALLANTOIN, SODIUM PCA, SODIUM HYALURONATE, METHYLHEPTYL ISOSTEARATE, BUTYLENE GLYCOL, CARBOMER, TETRASODIUM EDTA, AMINOMETHYL PROPANOL, PHENOXYETHANOL, PROPYLPARABEN, METHYLPARABEN, LIMONENE, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL.
Directions from packaging: Apply to hands at least once a day with a light massaging motion. Use more frequently during dry or cold weather.
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ingredients
| score | data gap | concerns | |
| METHYLPARABEN | 8 | 65% | Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes |
| LIMONENE | 6 | 56% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs) |
| VITAMIN A RETINOL | 5 | 70% | Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Organ system toxicity (non-reproductive), Biochemical or cellular level changes |
| PROPYLPARABEN | 4 | 82% | Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive) |
| TOCOPHERYL ACETATE | 4 | 81% | Allergies/immunotoxicity, Contamination concerns (HYDROQUINONE) |
| TETRASODIUM EDTA | 1 | 80% | Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards |
| PHENOXYETHANOL | 4 | 66% | Violations, restrictions & warnings, Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Occupational hazards |
| CYCLOPENTASILOXANE | 2 | 79% | Persistence and bioaccumulation |
| DIMETHICONE | 2 | 74% | Violations, restrictions & warnings |
| STEARIC ACID | 2 | 72% | Neurotoxicity, Irritation (skin, eyes, or lungs) |
| AMINOMETHYL PROPANOL | 3 | 69% | Irritation (skin, eyes, or lungs), Contamination concerns (NITROSAMINES, OXAZOLIDINE) |
| PANTHENOL | 2 | 88% | Multiple, additive exposure sources |
| GLYCERIN | 2 | 74% | Organ system toxicity (non-reproductive), Occupational hazards |
| CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL | 2 | 73% | Violations, restrictions & warnings |
| SODIUM PCA | 2 | 71% | Contamination concerns (NITROSAMINES) |
| SODIUM DIHYDROXYCETYL PHOSPHATE | 1 | 97% | none identified |
| CAPRYLIC/ CAPRIC TRIGLYCERIDE | 0 | 94% | none identified |
| ASCORBYL PALMITATE (VITAMIN C PALMITATE) | 1 | 88% | none identified |
| SODIUM HYALURONATE | 1 | 83% | none identified |
| BUTYLENE GLYCOL | 1 | 79% | Irritation (skin, eyes, or lungs) |
| C16-17 ALKYL BENZOATE | 0 | 100% | none identified |
| DI-C12-15 ALKYL FUMARATE | 0 | 100% | none identified |
| GINKGO BILOBA (MAIDENHAIR TREE) GINKGO BILOBA LEAF | 0 | 100% | none identified |
| GLYCYRRHIZA GLABRA (LICORICE) ROOT | 0 | 100% | none identified |
| LUPINUS ALBUS (WHITE LUPIN) SEED EXTRACT LUPINUS ALBUS SEED | 0 | 100% | none identified |
| METHYLHEPTYL ISOSTEARATE | 0 | 100% | none identified |
| ROSA CENTIFOLIA (CABBAGE ROSE) ROSA CENTIFOLIA FLOWER | 0 | 100% | none identified |
| SPIRULINA MAXIMA (ALGAE) | 0 | 100% | none identified |
| ALGAE | 0 | 100% | none identified |
| VITIS VINIFERA (GRAPE) SEED POWDER | 0 | 100% | none identified |
| ALLANTOIN | 0 | 94% | none identified |
| CARBOMER | 0 | 93% | none identified |
| WATER | 0 | 0% | innocuous |
Cancer*
*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more in vitro tests non-mammalian cells show positive mutation results | PHENOXYETHANOL, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL | |
| One or more animal studies show tumor formation at moderate doses | CYCLOPENTASILOXANE | |
| One or more in vitro tests on mammalian cells show positive mutation results | TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN, GLYCERIN | |
| Cancer - limited evidence | VITAMIN A | |
| Not likely to be carcinogenic in humans | STEARIC ACID | |
| Cancer - not classifiable/not likely to be human carcinogen | LIMONENE |
Developmental/reproductive toxicity*
*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show reproductive effects at high doses | BUTYLENE GLYCOL, | |
| One or more animal studies show developmental effects at high doses | LIMONENE | |
| One or more animal studies show reproductive effects at moderate doses | SODIUM HYALURONATE, GLYCERIN | |
| One or more animal studies show reproductive effects at low doses | VITAMIN A, | |
| One or more animal studies show any effects at low doses | PROPYLPARABEN |
Violations, restrictions & warnings*
*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | SODIUM PCA, AMINOMETHYL PROPANOL | |
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel | DIMETHICONE, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, LIMONENE | |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics | VITAMIN A, PHENOXYETHANOL | |
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | METHYLPARABEN |
Neurotoxicity*
*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show brain and nervous system effects at high doses | VITAMIN A, GLYCERIN, BUTYLENE GLYCOL | |
| One or more animal studies show brain and nervous system effects at moderate doses | SODIUM HYALURONATE, PHENOXYETHANOL, METHYLPARABEN, AMINOMETHYL PROPANOL, | |
| One or more animal studies show any effects at moderate doses | CYCLOPENTASILOXANE | |
| One or more animal studies show brain and nervous system effects at very low doses | STEARIC ACID |
Endocrine disruption*
*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show endocrine system disruption at high doses | STEARIC ACID, SODIUM PCA, PHENOXYETHANOL, GLYCERIN, BUTYLENE GLYCOL, AMINOMETHYL PROPANOL | |
| One or more studies show weak endocrine disruption | METHYLPARABEN | |
| One or more animal studies show endocrine disruption at moderate doses | CYCLOPENTASILOXANE | |
| Limited evidence of any disruption | PROPYLPARABEN |
Allergies/immunotoxicity*
*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Limited evidence of skin and immune system toxicity | PHENOXYETHANOL | |
| Human skin toxicant - strong evidence | TOCOPHERYL ACETATE, PROPYLPARABEN, METHYLPARABEN | |
| Known human immune system toxicant | LIMONENE |
Persistence and bioaccumulation*
*This table includes all possible persistence and bioaccumulation concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Persistent, bioaccumulative in wildlife | CYCLOPENTASILOXANE |
Organ system toxicity (non-reproductive)*
*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show liver effects at high doses (low dose studies may be unavailable for this ingredient) | CYCLOPENTASILOXANE, STEARIC ACID, SODIUM PCA, PANTHENOL, LIMONENE, BUTYLENE GLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE), AMINOMETHYL PROPANOL | |
| One or more animal studies show kidney or renal system effects at moderate doses (low dose studies may be unavailable for this ingredient) | TETRASODIUM EDTA, PHENOXYETHANOL, TOCOPHERYL ACETATE, SODIUM HYALURONATE | |
| Limited evidence of skin toxicity | VITAMIN A, PROPYLPARABEN | |
| One or more animal studies show kidney or renal system effects at very low doses | GLYCERIN | |
| Known human any toxicant | METHYLPARABEN |
Multiple, additive exposure sources*
*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Designated as safe for general or specific, limited use in food | VITAMIN A, TOCOPHERYL ACETATE, TETRASODIUM EDTA, STEARIC ACID, PROPYLPARABEN, METHYLPARABEN, GLYCERIN, LIMONENE, DIMETHICONE, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, BUTYLENE GLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Used in food or as an additive with limited or no toxicity information available | PANTHENOL |
Ecotoxicology*
*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Wildlife and environmental toxicity | LIMONENE, AMINOMETHYL PROPANOL, PROPYLPARABEN |
Irritation (skin, eyes, or lungs)*
*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| One or more animal studies show skin irritation at moderate doses | VITAMIN A, SODIUM HYALURONATE, SODIUM DIHYDROXYCETYL PHOSPHATE, GLYCERIN, CYCLOPENTASILOXANE, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL | |
| One or more animal studies show skin irritation at low doses | TETRASODIUM EDTA, STEARIC ACID, METHYLPARABEN | |
| Human any irritant - strong evidence | products for use around the eyes, on the skin, or may be aerosolized (airborne) | BUTYLENE GLYCOL |
| Classified as irritant | PHENOXYETHANOL, LIMONENE, AMINOMETHYL PROPANOL |
Data gaps*
*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | TOCOPHERYL ACETATE, TETRASODIUM EDTA, STEARIC ACID, PROPYLPARABEN, PHENOXYETHANOL, PANTHENOL, METHYLPARABEN, DIMETHICONE, VITAMIN A, CARBOMER, BUTYLENE GLYCOL, ASCORBYL PALMITATE (VITAMIN C PALMITATE) | |
| Not assessed for safety in cosmetics by industry panel | SODIUM DIHYDROXYCETYL PHOSPHATE, SPIRULINA MAXIMA (ALGAE), ALGAE, VITIS VINIFERA (GRAPE) SEED POWDER, GLYCYRRHIZA GLABRA (LICORICE) ROOT, LUPINUS ALBUS (WHITE LUPIN) SEED EXTRACT, METHYLHEPTYL ISOSTEARATE, ROSA CENTIFOLIA (CABBAGE ROSE), DI-C12-15 ALKYL FUMARATE, LIMONENE, GINKGO BILOBA (MAIDENHAIR TREE), GLYCERIN, CYCLOPENTASILOXANE, CITRUS GRANDIS (GRAPEFRUIT) PEEL OIL, CAPRYLIC/ CAPRIC TRIGLYCERIDE, C16-17 ALKYL BENZOATE, ALLANTOIN |
Occupational hazards*
*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Allowed workplace exposures restricted to moderate doses | GLYCERIN | |
| Allowed workplace exposures restricted to low doses | TETRASODIUM EDTA, PHENOXYETHANOL |
Biochemical or cellular level changes*
*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.
| type of concern | product conditions | ingredient(s) |
| Interferes with gene expresion | METHYLPARABEN | |
| Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | VITAMIN A | |
| One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood | GLYCERIN, CYCLOPENTASILOXANE |
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