Creme of Nature Permanent Hair Color 8.3 Caramel Blonde || Skin Deep: Cosmetic Safety Reviews

CREME OF NATURE PERMANENT HAIR COLOR 8.3 CARAMEL BLONDE

last updated: 08/15/07 brand: Creme of Nature by Colomer Group

SCORE

high hazard (out of 10)

79%

data gap

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98% of hair color and bleachings have lower concerns

COMPANY POLICIES

Compact for Safe Cosmetics
Non-signer: This company has not signed the Compact.

Animal Testing Policy
This company's animal testing policy is unknown.

Given the incomplete information made available by companies and the government, EWG provides additional information on personal care product ingredients from the published scientific literature. The chart below indicates that research studies have found that exposure to one or more ingredients in this product -- not the product itself -- caused the indicated health effect(s) in the studies reviewed by Skin Deep researchers. Actual health risks, if any, will vary based on the level of exposure to the ingredient and individual susceptibility -- information not available in Skin Deep.

Ingredients in this product are linked to:
	Cancer
	Developmental/reproductive toxicity
	Violations, restrictions & warnings
	Allergies/immunotoxicity
	Other concerns for ingredients used in this product: Neurotoxicity, Endocrine disruption, Organ system toxicity (non-reproductive), Miscellaneous, Multiple, additive exposure sources, Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns, Occupational hazards, Biochemical or cellular level changes

Ingredients from packaging: Conditioning Shampoo: Water (Aqua); Trideceth-7 Carboxylic Acid; Decyl Glucoside; Glycol Stearate; Polyquaternium-10; Aloe Barbadensis Leaf Extract; Hydrolyzed Milk Protein; Honey (Mel); Citrus Medica Limonum (Lemon) Extract; Triticum Vulgare (Wheat) Germ Oil; Abies Balsamea (Balsam Canada) Resin; Pectin; Lecithin; Foeniculum Vulgare (Fennel) Fruit Extract; Barosma Betulina Leaf Extract; Commiphora Abyssinica Extract; Origanum Majorana Leaf Extract; Iris Florentina Root Extract; Sodium Hydroxide; Fragrance (Parfum); Disodium EDTA; Methylparaben; Propylparaben; Quaternium-15; Methylchloroisothiazolinone; Methylisothiazolinone; Red 4 (CI 14700); Yellow 5 (CI 19140); Red 33 (CI 17200); Blue 1 (CI 42090). Creme Developer: Water (Aqua); Hydrogen Peroxide; Cetearyl Alcohol; Amodimethicone; Cetrimonium Chloride; Trideceth-12; Ceteareth-60; Ceteareth-23; Acrylates/Steareth-20 Itaconate Copolymer; Pentasodium Pentetate; Methylparaben; Phosphoric Acid; Sodium Stannate. Conditioning Colorant: Water (Aqua); Propylene Glycol; Laureth-1; Isostearic Acid; Glyceryl Stearate SE; Ammonium Hydroxide; Ethanolamine; Cocamidopropyl Betaine; Ammonium Lauryl Sulfate; Steartrimonium Chloride; Polyquaternium-10; Polyquaternium-28; Hydrolyzed Wheat Protein; Hydrolyzed Collagen; Erythorbic Acid; Sodium Sulfite; Tetrasodium EDTA; Fragrance (Parfum); p-Phenylenediamine; Resorcinol; p-Aminophenol; 2-Methylresorcinol; o-Aminophenol; Hydroquinone

Warnings from packaging: THIS PRODUCT CONTAINS INGREDIENTS WHICH MAY CAUSE SKIN IRRITATION ON CERTAIN INDIVIDUALS AND A PRELIMINARY TEST ACCORDING TO ACCOMPANYING DIRECTIONS SHOULD FIRST BE MADE. THIS PRODUCT MUST NOT BE USED FOR DYEING EYELASHES OR EYEBROWS. TO DO SO MAY CAUSE BLINDNESS.

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ingredients

	score	data gap	concerns
RESORCINOL	8	55%	Cancer, Violations, restrictions & warnings, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROQUINONE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
P-PHENYLENEDIAMINE	10	52%	Cancer, Developmental/reproductive toxicity, Violations, restrictions & warnings, Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
CETEARETH-60	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
CETEARETH-23	5	71%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
ETHANOLAMINE	5	63%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
O-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
P-AMINOPHENOL	8	57%	Cancer, Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Occupational hazards
FRAGRANCE	8	100%	Neurotoxicity, Allergies/immunotoxicity, Miscellaneous
HYDROGEN PEROXIDE	3	65%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
METHYLPARABEN	8	65%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Biochemical or cellular level changes
PROPYLENE GLYCOL	4	58%	Allergies/immunotoxicity, Irritation (skin, eyes, or lungs), Enhanced skin absorption
LECITHIN	4	70%	Multiple, additive exposure sources, Enhanced skin absorption, Contamination concerns (NITROSAMINES)
QUATERNIUM-15	6	65%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive), Contamination concerns (FORMALDEHYDE)
METHYLCHLOROISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
METHYLISOTHIAZOLINONE	6	63%	Violations, restrictions & warnings, Allergies/immunotoxicity
COCAMIDOPROPYL BETAINE	5	63%	Allergies/immunotoxicity, Contamination concerns (NITROSAMINES)
LAURETH-1	4	95%	Contamination concerns (ETHYLENE OXIDE, 1,4-DIOXANE)
PROPYLPARABEN	4	82%	Developmental/reproductive toxicity, Endocrine disruption, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
TETRASODIUM EDTA	1	80%	Irritation (skin, eyes, or lungs), Enhanced skin absorption, Occupational hazards
D&C RED 33 RED 33 (CI 17200)	1	75%	none identified
FD&C RED 4 RED 4 (CI 14700)	1	73%	none identified
PECTIN	2	88%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
SODIUM SULFITE	3	84%	Neurotoxicity, Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
FD&C YELLOW 5 YELLOW 5 (CI 19140)	2	82%	Neurotoxicity, Organ system toxicity (non-reproductive)
AMMONIUM HYDROXIDE	1	78%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
DISODIUM EDTA	3	78%	Neurotoxicity, Organ system toxicity (non-reproductive), Enhanced skin absorption
SODIUM HYDROXIDE	3	77%	Neurotoxicity, Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
AMMONIUM LAURYL SULFATE	1	73%	Irritation (skin, eyes, or lungs)
CETRIMONIUM CHLORIDE	3	71%	Allergies/immunotoxicity
QUATERNIUM-10 STEARTRIMONIUM CHLORIDE	3	70%	Allergies/immunotoxicity, Organ system toxicity (non-reproductive)
2-METHYLRESORCINOL	2	84%	Allergies/immunotoxicity
FD&C BLUE 1 BLUE 1 (CI 42090)	1	83%	none identified
PHOSPHORIC ACID	2	80%	Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs), Occupational hazards
HYDROLYZED WHEAT PROTEIN	1	95%	Allergies/immunotoxicity
HYDROLYZED MILK PROTEIN	1	94%	Multiple, additive exposure sources
CETEARYL ALCOHOL	0	93%	none identified
ISOSTEARIC ACID	0	93%	none identified
TRITICUM VULGARE (WHEAT) GERM OIL	1	90%	none identified
HYDROLYZED COLLAGEN	0	88%	none identified
SODIUM STANNATE	1	88%	Occupational hazards
TRIDECETH-12	1	88%	none identified
ERYTHORBIC ACID	1	87%	none identified
GLYCOL STEARATE	1	87%	none identified
ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT ALOE BARBADENSIS LEAF EXTRACT	1	75%	none identified
PENTASODIUM PENTETATE	0	74%	none identified
ACRYLATES/ STEARETH-20 ITACONATE COPOLYMER	0	100%	none identified
CITRUS MEDICA LIMONUM (LEMON) EXTRACT	0	100%	none identified
DECYL GLUCOSIDE	0	100%	none identified
FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT	0	100%	none identified
ORRIS EXTRACT IRIS FLORENTINA ROOT EXTRACT	0	100%	none identified
POLYQUATERNIUM-28	0	100%	none identified
BAROSMA BETULINA LEAF EXTRACT	0	100%	none identified
COMMIPHORA ABYSSINICA EXTRACT	0	100%	none identified
ORIGANUM MAJORANA (SWEET MARJORAM) LEAF EXTRACT ORIGANUM MAJORANA LEAF EXTRACT	0	100%	none identified
AMODIMETHICONE	0	99%	none identified
ABIES BALSAMEA (BALSAM)	0	94%	none identified
TRIDECETH-7 CARBOXYLIC ACID	0	94%	none identified
GLYCERYL STEARATE SE	0	93%	none identified
POLYQUATERNIUM-10	0	93%	none identified
HONEY	0	0%	innocuous
WATER	0	0%	innocuous

Cancer*

*This table includes all possible cancer concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests non-mammalian cells show positive mutation results		TRITICUM VULGARE (WHEAT) GERM OIL, QUATERNIUM-15, METHYLCHLOROISOTHIAZOLINONE, D&C RED 33, AMMONIUM HYDROXIDE
One or more in vitro tests on mammalian cells show positive mutation results		SODIUM SULFITE, SODIUM HYDROXIDE, PROPYLPARABEN, PROPYLENE GLYCOL, METHYLPARABEN, LAURETH-1, FD&C YELLOW 5, ETHANOLAMINE, ERYTHORBIC ACID, DISODIUM EDTA, CETRIMONIUM CHLORIDE
Mutagen - limited evidence		P-AMINOPHENOL, O-AMINOPHENOL
Cancer - not classifiable/not likely to be human carcinogen		RESORCINOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, FD&C RED 4, FD&C BLUE 1
Limited evidence of carcinogenicity		HYDROQUINONE

Developmental/reproductive toxicity*

*This table includes all possible developmental/reproductive toxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show reproductive effects at high doses		DISODIUM EDTA, ETHANOLAMINE, QUATERNIUM-15, FD&C YELLOW 5
One or more animal studies show reproductive effects at moderate doses		PROPYLENE GLYCOL, P-AMINOPHENOL, O-AMINOPHENOL
Human nervous system toxicant - moderate evidence		HYDROQUINONE, P-PHENYLENEDIAMINE
One or more animal studies show any effects at low doses		PROPYLPARABEN

Violations, restrictions & warnings*

*This table includes all possible violations, restrictions & warnings concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications		CETEARETH-23, QUATERNIUM-10, PROPYLENE GLYCOL, LECITHIN, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, HYDROQUINONE, ETHANOLAMINE, COCAMIDOPROPYL BETAINE, CETRIMONIUM CHLORIDE, CETEARETH-60, D&C RED 33, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT, AMMONIUM LAURYL SULFATE, RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, HYDROQUINONE, O-AMINOPHENOL
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel		P-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics		P-PHENYLENEDIAMINE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, HYDROQUINONE, RESORCINOL, METHYLCHLOROISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE
Violation of government restrictions - Banned or found unsafe for use in cosmetics		METHYLPARABEN

Neurotoxicity*

*This table includes all possible neurotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more in vitro tests on mammalian cells demonstrate neurotoxicity		METHYLISOTHIAZOLINONE
One or more animal studies show brain and nervous system effects at high doses		QUATERNIUM-15, PROPYLENE GLYCOL, FD&C BLUE 1
One or more animal studies show brain and nervous system effects at moderate doses		CETEARETH-23, RESORCINOL, QUATERNIUM-10, PHOSPHORIC ACID, P-AMINOPHENOL, O-AMINOPHENOL, METHYLPARABEN, LECITHIN, ETHANOLAMINE, CETEARETH-60
One or more animal studies show brain and nervous system effects at low doses		SODIUM SULFITE, DISODIUM EDTA
One or more animal studies show brain and nervous system effects at very low doses		SODIUM HYDROXIDE, HYDROGEN PEROXIDE, FD&C YELLOW 5
Moderate evidence of human neurotoxicity		FRAGRANCE
Strong evidence of human neurotoxicity		P-PHENYLENEDIAMINE, HYDROQUINONE

Endocrine disruption*

*This table includes all possible endocrine disruption concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show endocrine system disruption at high doses		QUATERNIUM-15, PROPYLENE GLYCOL, P-PHENYLENEDIAMINE, HYDROGEN PEROXIDE, HYDROQUINONE, ETHANOLAMINE, DISODIUM EDTA
One or more studies show weak endocrine disruption		METHYLPARABEN
Limited evidence of endocrine disruption		RESORCINOL, PROPYLPARABEN

Allergies/immunotoxicity*

*This table includes all possible allergies/immunotoxicity concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more human case studies show possible skin allergy effects		HYDROLYZED WHEAT PROTEIN
Human immune system toxicant - moderate evidence		SODIUM SULFITE, PECTIN
Limited evidence of skin and immune system toxicity		PROPYLENE GLYCOL
Human skin toxicant - strong evidence		QUATERNIUM-10, PROPYLPARABEN, METHYLPARABEN, ETHANOLAMINE, CETRIMONIUM CHLORIDE, 2-METHYLRESORCINOL
Known human immune system toxicant		RESORCINOL, QUATERNIUM-15, P-PHENYLENEDIAMINE, P-AMINOPHENOL, O-AMINOPHENOL, METHYLISOTHIAZOLINONE, METHYLCHLOROISOTHIAZOLINONE, HYDROQUINONE, FRAGRANCE, COCAMIDOPROPYL BETAINE

Organ system toxicity (non-reproductive)*

*This table includes all possible organ system toxicity (non-reproductive) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show metabolic effects at high doses (low dose studies may be unavailable for this ingredient)		PROPYLENE GLYCOL, ERYTHORBIC ACID, TRIDECETH-12
One or more animal studies show liver effects at moderate doses (low dose studies may be unavailable for this ingredient)		CETEARETH-23, CETEARETH-60, TETRASODIUM EDTA,
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)		FD&C BLUE 1
One or more animal studies show broad systemic effects at moderate doses (low dose studies may be unavailable for this ingredient)		GLYCOL STEARATE, CETRIMONIUM CHLORIDE, 2-METHYLRESORCINOL
Limited evidence of sense organ toxicity		PROPYLPARABEN, PHOSPHORIC ACID
One or more animal studies show broad systemic effects at low doses		RESORCINOL, QUATERNIUM-15, QUATERNIUM-10, DISODIUM EDTA, AMMONIUM HYDROXIDE
One or more animal studies show musculoskeletal effects at very low doses		FD&C YELLOW 5, SODIUM HYDROXIDE, HYDROGEN PEROXIDE
Possible human immune system toxicant		SODIUM SULFITE, PECTIN, P-AMINOPHENOL, O-AMINOPHENOL, METHYLCHLOROISOTHIAZOLINONE, ETHANOLAMINE
Known human respiratory toxicant		P-PHENYLENEDIAMINE, HYDROQUINONE, METHYLPARABEN

Miscellaneous*

*This table includes all possible miscellaneous concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Occupational hazards related to handling		SODIUM HYDROXIDE, PHOSPHORIC ACID, HYDROGEN PEROXIDE, ETHANOLAMINE, AMMONIUM HYDROXIDE
Ingredient not fully labeled - identity unknown		FRAGRANCE

Multiple, additive exposure sources*

*This table includes all possible multiple, additive exposure sources concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Designated as safe for general or specific, limited use in food		TETRASODIUM EDTA, SODIUM SULFITE, SODIUM HYDROXIDE, RESORCINOL, PROPYLPARABEN, PROPYLENE GLYCOL, PHOSPHORIC ACID, PECTIN, METHYLPARABEN, LECITHIN, HYDROGEN PEROXIDE, GLYCERYL STEARATE SE, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, FD&C YELLOW 5, FD&C BLUE 1, ETHANOLAMINE, ERYTHORBIC ACID, DISODIUM EDTA, CITRUS MEDICA LIMONUM (LEMON) EXTRACT, AMMONIUM HYDROXIDE
Used in food or as an additive with limited or no toxicity information available		LECITHIN, HYDROLYZED MILK PROTEIN

Ecotoxicology*

*This table includes all possible ecotoxicology concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Wildlife and environmental toxicity		RESORCINOL, P-PHENYLENEDIAMINE, P-AMINOPHENOL, HYDROQUINONE, AMMONIUM HYDROXIDE, PROPYLPARABEN

Irritation (skin, eyes, or lungs)*

*This table includes all possible irritation (skin, eyes, or lungs) concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show skin irritation at high doses		SODIUM SULFITE
One or more animal studies show skin irritation at moderate doses		TRIDECETH-12, TRITICUM VULGARE (WHEAT) GERM OIL, QUATERNIUM-15, QUATERNIUM-10, P-AMINOPHENOL, GLYCOL STEARATE
One or more animal studies show skin irritation at low doses		CETEARETH-23, TETRASODIUM EDTA, METHYLPARABEN, CETEARETH-60
One or more animal studies show skin irritation at very low doses		SODIUM HYDROXIDE, HYDROQUINONE, AMMONIUM LAURYL SULFATE
Human skin irritant - moderate evidence		PHOSPHORIC ACID, HYDROGEN PEROXIDE, ETHANOLAMINE, AMMONIUM HYDROXIDE
Classified as irritant		RESORCINOL, PROPYLENE GLYCOL, P-PHENYLENEDIAMINE

Data gaps*

*This table includes all possible data gaps concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Insufficient data to determine safety		P-PHENYLENEDIAMINE
Safety assessment was based on related chemical		PENTASODIUM PENTETATE, AMODIMETHICONE, PROPYLENE GLYCOL
Insufficient data to determine safety		P-AMINOPHENOL, O-AMINOPHENOL
Missing safety data noted by cosmetic industry review		PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, O-AMINOPHENOL, P-AMINOPHENOL, ISOSTEARIC ACID, ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		TRITICUM VULGARE (WHEAT) GERM OIL, SODIUM SULFITE, RESORCINOL, TETRASODIUM EDTA, QUATERNIUM-15, PROPYLPARABEN, POLYQUATERNIUM-10, PENTASODIUM PENTETATE, P-PHENYLENEDIAMINE, P-AMINOPHENOL, O-AMINOPHENOL, METHYLPARABEN, ISOSTEARIC ACID, HYDROLYZED COLLAGEN, GLYCOL STEARATE, GLYCERYL STEARATE SE, ERYTHORBIC ACID, DISODIUM EDTA, CETEARYL ALCOHOL
Not assessed for safety in cosmetics by industry panel		TRIDECETH-12
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		2-METHYLRESORCINOL, AMODIMETHICONE
Not assessed for safety in cosmetics by industry panel		ORIGANUM MAJORANA (SWEET MARJORAM) LEAF EXTRACT, COMMIPHORA ABYSSINICA EXTRACT, BAROSMA BETULINA LEAF EXTRACT, TRIDECETH-7 CARBOXYLIC ACID, SODIUM STANNATE, SODIUM HYDROXIDE, POLYQUATERNIUM-28, PHOSPHORIC ACID, PECTIN, ORRIS EXTRACT, LAURETH-1, HYDROLYZED WHEAT PROTEIN, HYDROLYZED MILK PROTEIN, HYDROGEN PEROXIDE, FRAGRANCE, FOENICULUM VULGARE (FENNEL) FRUIT EXTRACT, DECYL GLUCOSIDE, CITRUS MEDICA LIMONUM (LEMON) EXTRACT, AMMONIUM HYDROXIDE, ACRYLATES/ STEARETH-20 ITACONATE COPOLYMER, ABIES BALSAMEA (BALSAM)

Occupational hazards*

*This table includes all possible occupational hazards concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
Allowed workplace exposures restricted to low doses		SODIUM STANNATE, PHOSPHORIC ACID, HYDROQUINONE,
Allowed workplace exposures restricted to low doses		TETRASODIUM EDTA, RESORCINOL, O-AMINOPHENOL, P-AMINOPHENOL, HYDROGEN PEROXIDE, ETHANOLAMINE
Allowed workplace exposures restricted to very low doses		P-PHENYLENEDIAMINE
No workplace limits set		SODIUM HYDROXIDE

Biochemical or cellular level changes*

*This table includes all possible biochemical or cellular level changes concerns for the ingredients used by this manufacturer. Some categorizations depend on how the product is used or formulated.

type of concern	product conditions	ingredient(s)
One or more animal studies show biochemical changes at moderate doses where the human health implications are not yet well understood		P-AMINOPHENOL
One or more animal studies show biochemical changes at high doses where the human health implications are not yet well understood		HYDROGEN PEROXIDE, PROPYLENE GLYCOL
Interferes with gene expresion		METHYLPARABEN

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